logo
Julia Bradbury praises breast cancer study

Julia Bradbury praises breast cancer study

Yahoo24-05-2025

Television presenter Julia Bradbury has said a new study which concluded women with very dense breasts should be offered additional scans "could not come soon enough".
The 54-year-old, who was best known for presenting BBC One's Countryfile, was diagnosed with breast cancer in 2021 after a year and a half of tests.
A study led by the University of Cambridge said that other scans - not just traditional mammograms - could treble the number of cancers detected in these women.
"It is like looking for a snowball in a snowstorm, so this research could not come soon enough," Bradbury said.
Bradbury said she "found a lump" when she was travelling and got it checked.
After having a mammogram, Bradbury said she was "advised there was nothing to worry about".
"I was sitting in the chair about to leave the office with my consultant," she recalled.
"He said I am going to give you another ultrasound before you leave.
"Thank goodness I had that consultant."
Bradbury said a 6cm (2.4in) lump was found during the ultrasound, and she was sent for further tests.
"When I was having the biopsy I knew in my heart there was something seriously wrong, and those were the first tears I shed.
"I then had that horrible conversation of you have got cancer."
The trial, co-ordinated from Addenbrooke's Hospital in Cambridge, tested different scanning methods on women with very dense breasts who had only been given a mammogram and had originally been told they did not have cancer.
More than 9,000 women were involved in the study.
About one in 10 women have very dense breasts and have a higher risk of developing breast cancer.
Researchers said the cancers were harder to spot as they look whiter on the X-rays, the same colour as early-stage cancers.
"I did not think there was anything untoward about having dense breasts. However, there is a slight risk of breast cancer," added Bradbury, speaking to the BBC this week.
The Department of Health and Social Care said its screening advisory body had been looking at ways to improve detection rates in women with very dense breasts for a number of years.
It said it would be reviewing the findings of this trial, but it was determined to "fight cancer on all fronts" to improve survival rates.
A new national cancer plan for England is expected to be published later this year.
"This study has show that thousands of undetected cancers could be caught," Bradbury said.
"We have to try and be our own advocates and understand our body a little bit more."
Follow Cambridgeshire news on BBC Sounds, Facebook, Instagram and X.
Call for NHS to give women with dense breasts extra cancer scans
Permanent home approved for cancer support centre
Breast cancer survivors 'at risk' of second illness
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Orange background

Try Our AI Features

Explore what Daily8 AI can do for you:

Comments

No comments yet...

Related Articles

Why nightmares could make you age faster and die sooner
Why nightmares could make you age faster and die sooner

Yahoo

time2 hours ago

  • Yahoo

Why nightmares could make you age faster and die sooner

Frequent nightmares are linked to premature ageing and increase the risk of an early death, according to a new study. Adults who report weekly nightmares are more than three times likely to die before the age of 70 compared to those who rarely or never experience them, researchers found. The study found nightmares to be a 'stronger predictor of premature death' than smoking, obesity, poor diet, and low physical activity. The scientists warned the findings should be treated as a 'public health concern', but said people can reduce nightmares by managing stress. The team, led by Dr Abidemi Otaiku of the UK Dementia Research Institute, and Imperial College London, analysed data from 2,429 children aged eight to 10 and 183,012 adults aged 26 to 86 over a period of 19 years. The research, presented at the European Academy of Neurology (EAN) Congress this month, found that nightmares disrupt both sleep quality and duration, which impairs the body's overnight cellular restoration and repair ability. The combined impacts of chronic stress and disrupted sleep are likely to contribute to the accelerated ageing of our cells and bodies. Dr Otaiku said, 'Our sleeping brains cannot distinguish dreams from reality. That's why nightmares often wake us up sweating, gasping for breath, and with our hearts pounding – because our fight-or-flight response has been triggered. This stress reaction can be even more intense than anything we experience while awake.' He said: 'Nightmares lead to prolonged elevations of cortisol, a stress hormone closely linked to faster cellular ageing. For those who frequently experience nightmares, this cumulative stress may significantly impact the ageing process.' He added: 'Given how common and modifiable nightmares are, they should be taken far more seriously as a public health concern.' Researchers found that children and adults who had frequent nightmares also exhibited faster ageing. This accounted for approximately 40 per cent of those who had a higher risk of early death. Dr Otaiku said this was the first study to show nightmares can predict faster biological ageing and earlier mortality, even after accounting for other health issues. Even monthly nightmares were linked to faster ageing and increased mortality compared to those who had no nightmares. and the links were consistent across all ages, sexes, ethnicities, and mental health statuses. 'The good news is that nightmares can be prevented and treated,' said Dr Otaiku. Simple measures, such as maintaining good sleep hygiene, managing stress, seeking treatment for anxiety or depression and not watching scary films can be effective in reducing nightmares, he said.

Harbour BioMed Enters Global Strategic Collaboration with Otsuka to Advance BCMAxCD3 Bispecific T-Cell Engagers
Harbour BioMed Enters Global Strategic Collaboration with Otsuka to Advance BCMAxCD3 Bispecific T-Cell Engagers

Associated Press

time2 hours ago

  • Associated Press

Harbour BioMed Enters Global Strategic Collaboration with Otsuka to Advance BCMAxCD3 Bispecific T-Cell Engagers

CAMBRIDGE, Mass., ROTTERDAM, Netherlands and SHANGHAI, June 22, 2025 /PRNewswire/ -- Harbour BioMed (HKEX: 02142), a global biopharmaceutical company committed to the discovery and development of novel antibody therapeutics in immunology and oncology, today announced a global strategic collaboration with Otsuka Pharmaceutical Co., Ltd. ('Otsuka') to advance BCMAxCD3 bispecific T-cell engagers for the treatment of autoimmune diseases. Under the terms of the agreement, Otsuka is granted an exclusive license to develop, manufacture, and commercialize HBM7020, a BCMAxCD3 bispecific T-cell engager globally, excluding Greater China (Mainland China, Hong Kong, Macau and Taiwan). In return, Harbour BioMed will receive a total of $47 million in upfront and near-term payments. The company is also eligible for additional payments of up to $623 million upon the achievement of specified development and commercial milestones, as well as tiered royalties on future net sales. This strategic collaboration establishes a foundation for potential future partnerships between the two companies in the T-cell engager area. 'We are delighted to collaborate with Otsuka, a global healthcare leader renowned for its innovative approach to addressing unmet medical needs,' said Dr. Jingsong Wang, Founder, Chairman, and CEO of Harbour BioMed. 'This collaboration underscores the strength of Harbour BioMed's proprietary Harbour Mice® and HBICE® technology platforms, which enable the rapid development of fully human bispecific antibodies with optimized safety and efficacy profiles. By leveraging our unique capabilities, we are well-positioned to advance next-generation biotherapeutics that can make a meaningful difference in patients' lives worldwide.' Makoto Inoue, President and Representative Director of Otsuka Pharmaceutical, noted, 'Otsuka is expanding our development pipeline in the autoimmune disease field by leveraging the antibody drug platform of our subsidiary Visterra, and the small molecule drug discovery platform of our subsidiary Jnana. HBM7020 is expected to demonstrate efficacy in a broad range of autoimmune diseases in which B cells play a major role in disease pathogenesis, and we hope to contribute further to the field of specialized autoimmune diseases and thereby benefit patients.' About HBM7020 HBM7020 is a BCMAxCD3 bispecific antibody generated using Harbour BioMed's fully human HBICE® bispecific technology and Harbour Mice® platform. It is designed to crosslink target cells and T cells by binding to BCMA and CD3 on the cell surface, leading to potent T cell activation and targeted cell elimination. By incorporating dual anti-BCMA binding sites for enhanced cell targeting and monovalent-optimized CD3 activity to minimize cytokine release syndrome (CRS), HBM7020 has demonstrated potent cytotoxicity with broad therapeutic potential in both immunological and oncological diseases. In August 2023, HBM7020 obtained IND clearance from the National Medical Products Administration (NMPA) to commence a Phase I trial for cancer in China. About Harbour BioMed Harbour BioMed (HKEX: 02142) is a global biopharmaceutical company committed to the discovery and development of novel antibody therapeutics in immunology and oncology. The company is building a robust and differentiated pipeline through internal R&D capabilities, strategic global collaborations in co-discovery and co-development, and selective acquisitions. Harbour BioMed's proprietary antibody technology platform, Harbour Mice®, generates fully human monoclonal antibodies in both the conventional two heavy and two light chain (H2L2) format and the heavy chain-only (HCAb) format. Building upon HCAb antibodies, the HCAb-based immune cell engagers (HBICE®) bispecific antibody technology enables tumor-killing effects that traditional combination therapies cannot achieve. Additionally, the HCAb-based bispecific immune cell antagonist (HBICATM) technology empowers the development of innovative biologics for immunological and inflammatory diseases. By integrating Harbour Mice®, HBICE®, and HBICATM with a single B-cell cloning platform, Harbour BioMed has built a highly efficient and distinctive antibody discovery engine for developing next-generation therapeutic antibodies. For more information, please visit . About Otsuka Pharmaceutical Co., Ltd. Otsuka Pharmaceutical Co., Ltd. is a total healthcare company that focuses on each individual's potential to enhance their well-being. Our medical-related business provides treatments and diagnostics for both physical and mental health. Our nutraceutical business supports daily health maintenance and improvement. Otsuka's unique products and services are based on scientific evidence, under the guidance of our corporate philosophy: Otsuka-people creating new products for better health worldwide. For further information, please visit View original content to download multimedia: SOURCE Harbour BioMed

Mom of 8 with Stage 3 Breast Cancer Breaks Down in Tears After Unexpected Call From School Nurse (Exclusive)
Mom of 8 with Stage 3 Breast Cancer Breaks Down in Tears After Unexpected Call From School Nurse (Exclusive)

Yahoo

time3 hours ago

  • Yahoo

Mom of 8 with Stage 3 Breast Cancer Breaks Down in Tears After Unexpected Call From School Nurse (Exclusive)

Misty De La Cruz is a mother of eight who is battling an aggressive form of breast cancer Since her diagnosis in 2024, the 43-year-old has been open about her health struggles with her family, and especially with her children De La Cruz was heartbroken after she received an unexpected call from the elementary school nurse regarding her younger sonMisty De La Cruz was diagnosed with stage 3 triple-negative breast cancer in September 2024 after discovering a lump during one of her monthly self-exams. In May 2025, the Maryland-based mother of eight received an unexpected call from her son's elementary school. Over the phone, a nurse explained that the 10-year-old was frequently exhausted during school hours, telling the staff he's afraid to fall asleep most nights in fear that his mom might pass away overnight. De La Cruz filmed her emotional reaction to the heartbreaking phone call on TikTok, amassing over 3 million views. De La Cruz, who is battling the side effects of treatment while trying to maintain a stable family, says the emotional toll cancer takes extends far beyond the physical. For her, it's not just about surviving, it's about holding together a household deeply affected by fear and uncertainty. 'As a parent you try to be strong for your children, but they watch you slowly change into someone completely different,' De La Cruz tells PEOPLE exclusively. After her diagnosis, the 43-year-old sat down with her older children and was honest about what she was facing. It took a bit more time to have that conversation with her younger son. When she finally did, De La Cruz spoke with him one-on-one, gently explaining what cancer is and how it would impact both her health and their daily lives. 'He was crying, and the only thing he asked was if I was going to die,' she recalls. 'I tried to reassure him that the doctors were going to do the best that they could do to make sure that that didn't happen. But ultimately, there is never a promise from anyone, but I was gonna fight as hard as I could.' As months pass by, De La Cruz can no longer manage simple tasks she once took for granted. For example, standing in the kitchen to cook meals for her family is now a struggle. Chemotherapy has taken a serious toll on her body, and she often has negative reactions to the treatment and feels the side effects almost immediately. 'You lose all sense of humility or embarrassment because there are days when you can't even wash yourself and need assistance,' she explains. 'The debilitating pain from the neuropathy makes it impossible to even stand up at times. The bone and muscle pain from the injections made me need to use a walker at 42 years old because I couldn't even stand up on my own.' Working to cover basic expenses is also difficult, but even more heartbreaking is not being able to take care of her younger children when they're sick. She also has to miss her kids' activities because her weak immune system makes even a minor illness potentially life-threatening. 'You just feel helpless and useless and a burden all at the same time,' she candidly tells PEOPLE. While her children's schools were informed early on about her illness and have offered unwavering support, receiving a call from the elementary school nurse left her in tears. "It's one of those calls no parent wants to receive,' De La Cruz says. 'The feeling is gut-wrenching. It's almost like someone knocked the wind out of you, and you really don't know how to react to it. All I could do was cry.' When her son got home from school, she made sure they talked and decided that therapy was the best route for him. 'I allow my son to ask all of the questions he wants to ask, and I answer them honestly. I don't believe in tiptoeing around something or masking what the situation really is,' she reveals. 'We've had open discussions about my chances of survival as well as how it's going to change our lives on a daily basis.' Yet, no matter how sensitively she approaches the topic, De La Cruz still senses that her children worry about losing her. 'It doesn't take away the fear and a child's eyes as they watch the person who's always been the strongest in the household become the weakest,' she admits. De La Cruz has told each of her children that if they ever felt the need to talk to a professional, she would gladly arrange it. When it comes to creating small moments of normalcy around the house, De La Cruz says sticking to a routine helps a lot. 'No matter how sick I am, every Sunday our family has a Sunday dinner,' she reveals. 'Usually, I'm the one to do all the cooking, but we've had to improvise.' She's had to rely on her children more than ever, especially in the kitchen, as she can no longer stand for more than a few minutes at a time. Nevertheless, cooking together brings them joy. What she's learned through cancer is this: be honest with your children. Let them feel what they feel— anger, sadness, confusion. 'Everyone grieves differently,' she says, 'and this is a grieving process. You won't be the person you were before cancer.' Never miss a story — sign up for to stay up-to-date on the best of what PEOPLE has to offer​​, from celebrity news to compelling human interest stories. One of the hardest but most important lessons was learning to accept help. As someone deeply independent, leaning on others felt unnatural at first. But she came to understand that "it doesn't mean you're weak… It just means you're human – and even the strongest humans need help.' She wants others to know that the financial toll is real and often hidden. 'A lot of people fail to understand that just because you physically survive cancer, it doesn't mean that you emotionally mentally or financially survive it,' she emphasizes. 'I had to create a GoFundMe to attempt to not lose our home due to the unbelievable cost of trying to survive.' Her advice to others facing this journey is to speak openly, accept support, and don't be ashamed to ask for help. Survival isn't just about your body – it's about your whole life. And healing takes time. Read the original article on People

DOWNLOAD THE APP

Get Started Now: Download the App

Ready to dive into a world of global content with local flavor? Download Daily8 app today from your preferred app store and start exploring.
app-storeplay-store