Latest news with #Pixabay
Yahoo
2 hours ago
- Business
- Yahoo
Check Point Software Technologies Ltd (CHKP) Target Price Hiked at Mizuho to $240
Check Point Software Technologies Ltd. (NASDAQ:CHKP) is one of the 13 best software stocks to buy now. On June 16, analysts at Mizuho reiterated a 'Neutral' Rating on the stock but raised the price target to $240 from $230. The adjustment reflects the recent appreciation in the company's comparable multiples. Pixabay/Public Domain The company's head of investor relations, Kip Meintzer, has already noted that the company is yet to experience a negative impact from deteriorating macroeconomic conditions. Likewise, Meintzer expects Check Point Software's subscription revenue to grow significantly by the end of the year. On its part, Mizuho is confident that Checkpoint Software Technologies will benefit from healthy appliance refresh cycles throughout the year. Nevertheless, the research firm has stuck with the neutral rating, insisting the company has much to prove on reaccelerating the business. Mizuho's price target hike also comes on the heels of Checkpoint Software Technologies' announcement of the acquisition of Veriti Cybersecurity. The acquisition is poised to enhance its hybrid mesh security vision. Check Point Software Technologies Ltd. (NASDAQ:CHKP) develops, markets, and supports a range of products and services for IT security worldwide. It provides a multilevel security architecture that defends enterprises' cloud, network, mobile devices, endpoint information, and IOT solutions. While we acknowledge the potential of CHKP as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock. READ NEXT: 12 Best Healthcare Stocks to Buy Now and 10 Stocks Analysts Are Upgrading Today. Disclosure: None.
Edinburgh Reporter
4 hours ago
- Health
- Edinburgh Reporter
Turning Data into Decisions The Power of Clinical Data Management in Modern Trials
Every clinical trial, no matter how complex or straightforward, generates data. From laboratory results and electronic case report forms to adverse event reports and patient-reported outcomes, the flow of data is constant and massive. Yet, raw data alone is not useful — it must be structured, validated, and transformed into reliable evidence that supports regulatory approval and, ultimately, clinical decisions. This is where clinical research data management services play an indispensable role. Why Is Data Management So Critical in Clinical Trials? In today's clinical environment, the speed and success of a study are increasingly determined by how efficiently data is handled. Sponsors, regulators, and investigators depend on high-quality, timely information to make protocol adjustments, conduct safety reviews, and prepare submissions. Poor data management can delay a trial, increase costs, or even invalidate results. Good data management ensures: Integrity of the study database Compliance with global regulatory standards Real-time monitoring of trial progress Faster insights for interim and final analyses Improved collaboration across teams Modern clinical trials cannot afford to treat data handling as an afterthought. It must be embedded from day one. What Do Data Management Services Typically Include? Clinical research data management services encompass a wide range of responsibilities, technologies, and workflows — all aimed at ensuring clean, accurate, and compliant data throughout the trial lifecycle. Some of the core components include: Case Report Form (CRF) design : Structuring questions and data fields for clarity and completeness : Structuring questions and data fields for clarity and completeness Electronic Data Capture (EDC) systems : Platforms for collecting and storing data securely : Platforms for collecting and storing data securely Query management : Identifying and resolving discrepancies or missing data : Identifying and resolving discrepancies or missing data Database validation and cleaning : Regular checks for consistency, outliers, or protocol deviations : Regular checks for consistency, outliers, or protocol deviations Data coding : Standardizing medical terms (e.g., MedDRA, WHO-DD) for analysis : Standardizing medical terms (e.g., MedDRA, WHO-DD) for analysis Data transfer and locking: Secure sharing of final datasets with statisticians and regulatory teams A well-functioning data management team works quietly behind the scenes, but their impact is felt throughout the trial — especially when problems are avoided or quickly resolved. EDC platforms (e.g., Medidata, Veeva, REDCap) Clinical Trial Management Systems (CTMS) ePRO and eCOA tools for patient input Risk-based monitoring dashboards Validation scripts and automated edit checks Image by Konstantin Kolosov from Pixabay Challenges and Solutions in Managing Trial Data Despite advances in technology, data management is not without its hurdles. Trials are becoming more decentralized, data sources are more diverse, and expectations for real-time insights are growing. Managing this complexity requires both technical skill and strategic thinking. Let's explore some common challenges and how experienced data managers address them: Decentralized data collection With patients submitting data via mobile apps, wearables, or home diagnostics, data managers must integrate and validate new input formats without compromising consistency. With patients submitting data via mobile apps, wearables, or home diagnostics, data managers must integrate and validate new input formats without compromising consistency. Protocol amendments mid-trial When protocols change, CRFs and data pipelines must be updated immediately — without jeopardizing data already collected. Agile EDC systems and flexible coding structures are essential. When protocols change, CRFs and data pipelines must be updated immediately — without jeopardizing data already collected. Agile EDC systems and flexible coding structures are essential. Cross-system integration Studies often involve multiple software platforms. Data teams must ensure smooth integration and unified reporting, especially when working with third-party labs or imaging providers. Studies often involve multiple software platforms. Data teams must ensure smooth integration and unified reporting, especially when working with third-party labs or imaging providers. Global data privacy compliance Regulations like GDPR and HIPAA mandate strict controls over patient information. Data managers ensure anonymization, encryption, and secure access at every stage. Regulations like GDPR and HIPAA mandate strict controls over patient information. Data managers ensure anonymization, encryption, and secure access at every stage. Fast database lock expectations Sponsors want results quickly. Data teams must balance speed with quality, preparing for interim analyses or regulatory submissions without rushing validation. Experienced providers of clinical research data management services anticipate these issues. Their processes are built to handle complexity, mitigate risks, and deliver results — often under significant time pressure. Why Outsourcing Data Management Makes Sense Many sponsors — especially smaller biotech or device companies — don't have in-house capacity to manage trial data effectively. Partnering with an external data management provider offers: Access to specialized expertise and tools Scalable support across multiple studies Greater consistency in data standards and coding Seamless integration with biostatistics and regulatory teams Cost-efficiency through centralized infrastructure However, choosing the right partner is essential. Sponsors should evaluate potential providers not only on technology, but also on experience with specific therapeutic areas, audit history, and adaptability to evolving trial designs. From Numbers to Knowledge Ultimately, the true value of data management lies in its ability to turn chaos into clarity. Clean, structured, and timely data enables more than just trial completion — it fuels insights, accelerates innovation, and drives better health outcomes. Whether through centralized databases, AI-assisted cleaning tools, or dedicated query resolution teams, modern clinical data handling has become a cornerstone of successful studies. In a world where speed, safety, and transparency are non-negotiable, data management is no longer a back-office function — it's a front-line driver of progress. Like this: Like Related
Mint
10 hours ago
- Health
- Mint
Yoga Day special: 10 powerful yoga poses and their incredible benefits for a healthier life
Yoga Day special: 10 powerful yoga poses and their incredible benefits for a healthier life 10 Photos . Updated: 20 Jun 2025, 11:06 AM IST Share Via International Yoga Day is observed worldwide every year on June 21. This year's theme is 'Yoga for One Earth, One Health.' In celebration, here are some yoga poses that promote a healthier and more balanced life. 1/10The Tree pose may appear simple, but it is not a resting posture. Proper alignment is key—your back should be elongated, hips level, and weight evenly distributed on the standing leg. This pose challenges and enhances your balance while building strength and focus. (Pixabay ) 2/10The Chair yoga pose helps tone the leg muscles and strengthen the hip flexors, ankles, calves, and back. It also stretches the chest and shoulders, alleviates symptoms of flat feet, and stimulates the heart, diaphragm, and abdominal organs for improved overall function. (Pinterest ) 3/10The Four-Limbed Staff pose helps build strength in the arms, wrists, and core. It's also an excellent foundational pose to prepare the body for more advanced arm-balancing postures. (Pexels ) 4/10The Triangle pose offers a wide range of benefits for the body. It enhances spinal flexibility, supports proper shoulder alignment, and helps relieve back pain and neck stiffness. (Pexels ) 5/10The Warrior II yoga pose strengthens the legs and arms, opens the chest and shoulders, and engages the abdominal muscles. Regulating your breath and focusing on the extension of your arms can help cultivate patience. Maintain an elevated posture—avoid collapsing into your hips and resist the pull of gravity. Stay grounded and strong. (Pexels ) 6/10Warrior I is an ideal pose for unwinding after a stressful day, helping to relax both the body and mind. Its benefits are far-reaching: it builds strength in the knees and feet, stretches the shoulders and spine, and enhances concentration and focus. (Pexels ) 7/10The Easy Pose might appear simple, but it offers numerous benefits for the body. It serves as a gentle hip opener, promotes relaxation, reduces anxiety, and can help ease menstrual discomfort in women. When practising this pose, be sure to keep your spine straight for maximum effect. (Pexels ) 8/10Child's Pose is a gentle resting posture that helps relieve tension in the neck, back, and hips. While in this pose, focus on slow, steady breathing with arms extended, hips relaxed, and forehead resting on the mat. It's one of the most calming and restorative poses, making it a safe place to return to anytime during your practice. (Pexels ) 9/10The Downward Dog yoga pose helps lengthen and decompress the spine, stretches the hamstrings, strengthens the arms, boosts oxygen flow to the brain, and promotes a sense of mental calm. (Pexels)
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First Post
10 hours ago
- Politics
- First Post
How is uranium enrichment used to make nuclear bombs?
Israel targeted Iran's nuclear facilities at Natanz, Isfahan, and Fordow, killing several scientists. These sites are crucial for uranium enrichment, a process that is used to produce nuclear power but can be exploited to make nuclear weapons. How does it work? read more Natanz and Fordow are Iran's uranium enrichment sites, and Isfahan provides the raw materials, so any damage to these sites would limit Iran's ability to produce nuclear weapons. Image for Representation. Reuters Late last week, Israel targeted three of Iran's key nuclear facilities – Natanz, Isfahan and Fordow, killing several Iranian nuclear scientists. The facilities are heavily fortified and largely underground, and there are conflicting reports of how much damage has been done. Natanz and Fordow are Iran's uranium enrichment sites, and Isfahan provides the raw materials, so any damage to these sites would limit Iran's ability to produce nuclear weapons. But what exactly is uranium enrichment and why does it raise concerns? STORY CONTINUES BELOW THIS AD To understand what it means to 'enrich' uranium, you need to know a little about uranium isotopes and about splitting the atom in a nuclear fission reaction. What is an isotope? All matter is made of atoms, which in turn are made up of protons, neutrons and electrons. The number of protons is what gives atoms their chemical properties, setting apart the various chemical elements. Atoms have equal numbers of protons and electrons. Uranium has 92 protons, for example, while carbon has six. However, the same element can have different numbers of neutrons, forming versions of the element called isotopes. This hardly matters for chemical reactions, but their nuclear reactions can be wildly different. Uranium-238 vs Uranium-235 When we dig uranium out of the ground, 99.27 per cent of it is uranium-238, which has 92 protons and 146 neutrons. Only 0.72 per cent of it is uranium-235 with 92 protons and 143 neutrons (the remaining 0.01 per cent are other isotopes). For nuclear power reactors or weapons, we need to change the isotope proportions. That's because of the two main uranium isotopes, only uranium-235 can support a fission chain reaction: one neutron causes an atom to fission, which produces energy and some more neutrons, causing more fission, and so on. This chain reaction releases a tremendous amount of energy. In a nuclear weapon, the goal is to have this chain reaction occur in a fraction of a second, producing a nuclear explosion. A nuclear power plant. Image for Representation. Pixabay In a civilian nuclear power plant, the chain reaction is controlled. Nuclear power plants currently produce 9 per cent of the world's power. Another vital civilian use of nuclear reactions is for producing isotopes used in nuclear medicine for the diagnosis and treatment of various diseases. What is uranium enrichment? To 'enrich' uranium means taking the naturally found element and increasing the proportion of uranium-235 while removing uranium-238. There are a few ways to do this ( including new inventions from Australia), but commercially, enrichment is currently done with a centrifuge. This is also the case in Iran's facilities. STORY CONTINUES BELOW THIS AD Centrifuges exploit the fact that uranium-238 is about 1 per cent heavier than uranium-235. They take uranium (in gas form) and use rotors to spin it at 50,000 to 70,000 rotations per minute, with the outer walls of the centrifuges moving at 400 to 500 metres per second. Commercially, enrichment is currently done with a centrifuge. File image/ Reuters This works much like a salad spinner that throws water to the sides while the salad leaves stay in the centre. The heavier uranium-238 moves to the edges of the centrifuge, leaving the uranium-235 in the middle. This is only so effective, so the spinning process is done over and over again, building up the percentage of the uranium-235. Most civilian nuclear reactors use 'low enriched uranium' that's been enriched to between 3 per cent and 5 per cent. This means that 3–5% of the total uranium in the sample is now uranium-235. That's enough to sustain a chain reaction and make electricity. How does enrichment make nuclear weapons? To get an explosive chain reaction, uranium-235 needs to be concentrated significantly more than the levels we use in nuclear reactors for making power or medicines. Technically, a nuclear weapon can be made with as little as 20 per cent uranium-235 (known as 'highly enriched uranium'), but the more the uranium is enriched, the smaller and lighter the weapon can be. Countries with nuclear weapons tend to use about 90 per cent enriched, 'weapons-grade' uranium. STORY CONTINUES BELOW THIS AD According to the International Atomic Energy Agency (IAEA), Iran has enriched large quantities of uranium to 60 per cent. It's actually easier to go from an enrichment of 60 per cent to 90 per cent than it is to get to that initial 60 per cent. That's because there's less and less uranium-238 to get rid of. This is why Iran is considered to be at extreme risk of producing nuclear weapons, and why centrifuge technology for enrichment is kept secret. Ultimately, the exact same centrifuge technology that produces fuel for civilian reactors can be used to produce nuclear weapons. Inspectors from the IAEA monitor nuclear facilities worldwide to ensure countries are abiding by the rules set out in the global nuclear non-proliferation treaty. While Iran maintains it's only enriching uranium for 'peaceful purposes', late last week the IAEA board ruled Iran was in breach of its obligations under the treaty. Kaitlin Cook, DECRA Fellow, Department of Nuclear Physics and Accelerator Applications, Australian National University STORY CONTINUES BELOW THIS AD This article is republished from The Conversation under a Creative Commons license. Read the original article.
Time of India
10 hours ago
- Health
- Time of India
International Yoga Day quote 2025: 30+ wishes, messages, images, Instagram captions & WhatsApp status
International Yoga Day 2025 | Credit: Pixabay International Yoga Day wishes & quotes 2025: International Yoga Day 2025 will be celebrated on June 21 across the world, promoting the incredible benefits of yoga for both mind and body. This year marks the 11th anniversary of International Yoga Day, and the global theme for 2025 is 'Yoga for One Earth, One Health', echoing India's message during its G20 presidency. Why We Celebrate International Yoga Day International Yoga Day is more than just an occasion; it's a movement to raise awareness about the importance of practising yoga daily. Yoga helps improve physical health, boosts mental well-being, and strengthens emotional balance. In 2025, let's unite in celebrating yoga and its power to bring peace, strength, and harmony to our lives. People express their love for yoga by sharing International Yoga Day quotes, wishes, messages, images, Instagram captions, and WhatsApp status with their friends, family, and followers. International Yoga Day 2025 Wishes & Messages to Share Spread positivity with these International Yoga Day 2025 messages and wishes: Happy International Yoga Day 2025! May your body stay strong, your mind stay calm, and your spirit stay bright. On this special day, let yoga fill your life with health, happiness, and harmony. Let's celebrate the gift of yoga and the peace it brings into our lives. May your yoga journey bring you inner peace and balance. Happy Yoga Day! Embrace yoga for a healthier body, mind, and soul. Happy International Yoga Day! Take a breath, stretch your body, and feel the calm. Happy Yoga Day 2025! May yoga become a way of life for you. Wishing you peace and good health on International Yoga Day. Yoga is not just about flexibility, it's about balance and growth. Happy Yoga Day! Celebrate unity, mindfulness, and well-being through yoga. On this International Yoga Day, let's promise to live healthier, happier, and more mindful lives. Yoga is a journey of the self, through the self, to the self. Namaste. Wishing you a relaxing and rejuvenating International Yoga Day 2025. May your yoga practice help you stay grounded and grateful every day. Breathe deeply, stretch gently, and smile often. Happy International Yoga Day! Bring calm into your chaos. Let yoga guide your path. Unroll your mat and embrace stillness. Happy Yoga Day! This International Yoga Day, breathe out stress and breathe in peace. Let yoga be your daily dose of happiness and harmony. Yoga brings balance, yoga brings joy. Happy Yoga Day 2025! Celebrate the power of yoga to transform and heal. Best Quotes for International Yoga Day 2025 Here are some inspiring International Yoga Day quotes to share on social media or write in greeting cards: 'Yoga is the journey of the self, through the self, to the self.' – Bhagavad Gita 'Yoga is not about touching your toes, it's about what you learn on the way down.' – Jigar Gor 'Inhale the future, exhale the past.' – Unknown 'The body is your temple. Keep it pure and clean for the soul to reside in.' – B.K.S. Iyengar 'Yoga teaches us to cure what need not be endured and endure what cannot be cured.' – B.K.S. Iyengar 'Yoga is the art work of awareness on the canvas of body, mind, and soul.' – Amit Ray 'Yoga begins right where I am – not where I was yesterday.' – Linda Sparrowe 'Yoga is a light, which once lit, will never dim.' – B.K.S. Iyengar 'Yoga is a mirror to look at ourselves from within.' – Unknown 'Yoga is the fountain of youth. You're only as young as your spine is flexible.' – Bob Harper 'The attitude of gratitude is the highest yoga.' – Yogi Bhajan 'Yoga is the dance of every cell with the music of every breath.' – Debasish Mridha 'True yoga is not about the shape of your body, but the shape of your life.' – Aadil Palkhivala 'Yoga is the perfect opportunity to be curious about who you are.' – Jason Crandell 'Yoga does not just change the way we see things, it transforms the person who sees.' – B.K.S. Iyengar 'Let your practice be a celebration of life.' – Seido Lee deBarros 'Yoga is for every body, every age, and every soul.' – Unknown 'Yoga is the best therapy for mind and body.' – Unknown 'Start your day with yoga and see the magic unfold.' – Unknown 'Yoga adds years to your life and life to your years.' – Unknown Captions & Status for Instagram & WhatsApp on International Yoga Day 2025 Make your posts stand out with these Instagram captions and WhatsApp status ideas for International Yoga Day 2025: One pose at a time, one breath at a time. #InternationalYogaDay2025 Yoga is my happy place. 🌿🧘♀️ Stretch, breathe, grow. Happy Yoga Day! Let's roll out the mat and celebrate stillness. Yoga: The art of getting back to yourself. Yoga brings peace to the storm within. Mindful moves. Peaceful thoughts. #YogaDay Flexibility is just a bonus. Yoga is about the soul. Yoga is not just exercise; it's a way of life. Breathe deeply and move mindfully. #Yoga2025 Calm mind, healthy body, peaceful soul. A small step on the mat brings big changes in life. Share International Yoga Day 2025 Images On this International Yoga Day, don't forget to share beautiful images that promote yoga and well-being. Share motivational yoga pictures, illustrations of yoga poses, and spiritual graphics across WhatsApp, Instagram, and Facebook to inspire your loved ones. You can create your own or find HD-quality International Yoga Day 2025 images online that reflect the spirit of unity and health. International Yoga Day 2025 reminds us of the power of yoga to bring people together and promote a balanced, healthy lifestyle. Whether you're a beginner or a seasoned yogi, this day is perfect to restart your practice and inspire others. Share these heartwarming International Yoga Day quotes, wishes, images, captions, and status updates with your friends and family. Let's celebrate yoga for health, harmony, and happiness! For more informative articles on historical and upcoming events from around the world, please visit Indiatimes Events. First Published: Jun 20, 2025, 10:35 IST Bhupinder Singh serves as a Principal Executive in Content Management, specializing in SEO content related to trending financial news, net worth of celebrities, historic events, and art and culture. His passion for cricket shines through in his work and personal interests. In his free time, Bhupinder enjoys discussing cricket legends like MS Dhoni and Sachin Tendulkar, as well as following the IPL. Read More 20/6/2025 11:1:40
