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Dr explains: How to spot early Alzheimer's symptoms and why younger adults should care too
Alzheimer's disease isn't just a condition of old age. Subtle symptoms can appear earlier than expected and are often mistaken for routine forgetfulness. Firstpost spoke to an expert on how to recognise the red flags, distinguish the disease from normal ageing, and adopt preventive measures to protect brain health early. read more
Alzheimer's disease, often thought to be a condition of old age, can begin far earlier than most people realise and the signs aren't always as obvious as memory loss. With rising stress levels, lifestyle diseases, and increasing life expectancy, the burden of Alzheimer's in India is expected to climb sharply in the coming decades. Despite this, many people remain unaware of its early warning signs, confusing them with routine forgetfulness or age-related decline.
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Firstpost spoke to Dr Pooja Anand, Associate Consultant – Neurology at Paras Health (Gurugram) to shed light on how Alzheimer's differs from normal aging, the red flags to watch for and how prevention can start well before retirement age.
What exactly is Alzheimer's disease, and how is it typically identified in its early stages?
Alzheimer's disease is a progressive neurodegenerative disorder that primarily impairs memory and cognitive function. In its early stages, it often manifests as subtle memory lapses such as forgetting names or recent events—that gradually become more pronounced. These changes go beyond ordinary forgetfulness and begin to interfere with daily life and routine functioning. Diagnosis typically involves clinical evaluations, cognitive testing, brain imaging, and in some cases, biomarker testing.
How does Alzheimer's differ from normal age-related memory loss or forgetfulness?
It's important to distinguish Alzheimer's from normal aging. Occasional forgetfulness—like misplacing keys or struggling to recall a name but remembering it later—is common with age. However, Alzheimer's involves persistent memory loss, confusion, and difficulty with reasoning or problem-solving. People may get lost in familiar places or have trouble following conversations—warning signs that extend beyond normal aging.
At what age does the risk of developing Alzheimer's disease begin to significantly increase?
The risk of Alzheimer's rises significantly after the age of 65. That said, it's not exclusively a disease of old age. Early-onset Alzheimer's, though rare, can appear in individuals as young as their 40s or 50s. As age is the strongest risk factor, cases rise sharply among people in their 70s and 80s.
What are some early warning signs or red flags that people should look out for in Alzheimer's or other forms of dementia?
Early warning signs include memory loss that disrupts daily life, trouble completing familiar tasks, confusion about time or place, and difficulty understanding visual images or spatial relationships. Changes in mood, personality, or social withdrawal can also be indicators. Persistent or worsening symptoms should prompt further medical assessment.
What are some common myths or misconceptions surrounding Alzheimer's disease?
A common myth is that Alzheimer's is simply part of normal aging—which it is not. Another misconception is that only the elderly are affected, when in fact early-onset cases do exist. There's also a belief that nothing can be done after diagnosis. In reality, early intervention, appropriate support, and available treatments can help manage symptoms and improve quality of life.
How much of a concern is early-onset Alzheimer's, and how frequently does it occur compared to cases in older adults?
Early-onset Alzheimer's is relatively uncommon, accounting for 5–10% of all cases. However, it is particularly concerning as it strikes during an individual's working years and can be more difficult to diagnose due to its unexpected timing. In some cases, the disease also progresses more aggressively, making early detection and treatment crucial.
Does the treatment approach differ between early-onset and late-onset Alzheimer's patients?
Core treatment strategies—managing symptoms, slowing disease progression, and supporting patients and caregivers—are generally the same. However, early-onset patients often face additional challenges related to employment, finances, and parenting, requiring specialised psychosocial support and care planning tailored to their unique circumstances.
Is there evidence linking cardiovascular health—like heart disease or hypertension—to a higher risk of Alzheimer's, especially among younger adults in India?
Yes, growing evidence suggests a strong link between cardiovascular and brain health. Conditions like hypertension, diabetes, and obesity—which are increasingly common among younger adults in India—can raise the risk of cognitive decline. Poor cardiovascular health can reduce blood flow to the brain, which may contribute to Alzheimer's and other dementias over time.
What lifestyle habits or preventive measures can individuals adopt to reduce their risk of developing Alzheimer's disease later in life?
A brain-healthy lifestyle can play a major role in prevention. This includes regular physical exercise, a balanced diet rich in fruits, vegetables, and healthy fats (such as the Mediterranean diet), mental stimulation, good quality sleep, and social engagement. Managing stress, avoiding smoking, and controlling blood pressure and blood sugar are also key. In short, what benefits the heart also benefits the brain.

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Daily Olive Oil Intake May Cut Dementia Death Risk By 28 Per Cent: Study
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First Post
8 hours ago
- First Post
Dr explains: How to spot early Alzheimer's symptoms and why younger adults should care too
Alzheimer's disease isn't just a condition of old age. Subtle symptoms can appear earlier than expected and are often mistaken for routine forgetfulness. Firstpost spoke to an expert on how to recognise the red flags, distinguish the disease from normal ageing, and adopt preventive measures to protect brain health early. read more Alzheimer's disease, often thought to be a condition of old age, can begin far earlier than most people realise and the signs aren't always as obvious as memory loss. With rising stress levels, lifestyle diseases, and increasing life expectancy, the burden of Alzheimer's in India is expected to climb sharply in the coming decades. Despite this, many people remain unaware of its early warning signs, confusing them with routine forgetfulness or age-related decline. STORY CONTINUES BELOW THIS AD Firstpost spoke to Dr Pooja Anand, Associate Consultant – Neurology at Paras Health (Gurugram) to shed light on how Alzheimer's differs from normal aging, the red flags to watch for and how prevention can start well before retirement age. What exactly is Alzheimer's disease, and how is it typically identified in its early stages? Alzheimer's disease is a progressive neurodegenerative disorder that primarily impairs memory and cognitive function. In its early stages, it often manifests as subtle memory lapses such as forgetting names or recent events—that gradually become more pronounced. These changes go beyond ordinary forgetfulness and begin to interfere with daily life and routine functioning. Diagnosis typically involves clinical evaluations, cognitive testing, brain imaging, and in some cases, biomarker testing. How does Alzheimer's differ from normal age-related memory loss or forgetfulness? It's important to distinguish Alzheimer's from normal aging. Occasional forgetfulness—like misplacing keys or struggling to recall a name but remembering it later—is common with age. However, Alzheimer's involves persistent memory loss, confusion, and difficulty with reasoning or problem-solving. People may get lost in familiar places or have trouble following conversations—warning signs that extend beyond normal aging. At what age does the risk of developing Alzheimer's disease begin to significantly increase? The risk of Alzheimer's rises significantly after the age of 65. That said, it's not exclusively a disease of old age. Early-onset Alzheimer's, though rare, can appear in individuals as young as their 40s or 50s. As age is the strongest risk factor, cases rise sharply among people in their 70s and 80s. What are some early warning signs or red flags that people should look out for in Alzheimer's or other forms of dementia? Early warning signs include memory loss that disrupts daily life, trouble completing familiar tasks, confusion about time or place, and difficulty understanding visual images or spatial relationships. Changes in mood, personality, or social withdrawal can also be indicators. Persistent or worsening symptoms should prompt further medical assessment. What are some common myths or misconceptions surrounding Alzheimer's disease? A common myth is that Alzheimer's is simply part of normal aging—which it is not. Another misconception is that only the elderly are affected, when in fact early-onset cases do exist. There's also a belief that nothing can be done after diagnosis. In reality, early intervention, appropriate support, and available treatments can help manage symptoms and improve quality of life. How much of a concern is early-onset Alzheimer's, and how frequently does it occur compared to cases in older adults? Early-onset Alzheimer's is relatively uncommon, accounting for 5–10% of all cases. However, it is particularly concerning as it strikes during an individual's working years and can be more difficult to diagnose due to its unexpected timing. In some cases, the disease also progresses more aggressively, making early detection and treatment crucial. Does the treatment approach differ between early-onset and late-onset Alzheimer's patients? Core treatment strategies—managing symptoms, slowing disease progression, and supporting patients and caregivers—are generally the same. However, early-onset patients often face additional challenges related to employment, finances, and parenting, requiring specialised psychosocial support and care planning tailored to their unique circumstances. Is there evidence linking cardiovascular health—like heart disease or hypertension—to a higher risk of Alzheimer's, especially among younger adults in India? Yes, growing evidence suggests a strong link between cardiovascular and brain health. Conditions like hypertension, diabetes, and obesity—which are increasingly common among younger adults in India—can raise the risk of cognitive decline. Poor cardiovascular health can reduce blood flow to the brain, which may contribute to Alzheimer's and other dementias over time. What lifestyle habits or preventive measures can individuals adopt to reduce their risk of developing Alzheimer's disease later in life? A brain-healthy lifestyle can play a major role in prevention. This includes regular physical exercise, a balanced diet rich in fruits, vegetables, and healthy fats (such as the Mediterranean diet), mental stimulation, good quality sleep, and social engagement. Managing stress, avoiding smoking, and controlling blood pressure and blood sugar are also key. In short, what benefits the heart also benefits the brain.
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Fighting a genetic enemy: How sickle cell disease quietly impacts childhood in India
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Reliance Foundation Hospital; Dr. Gaurav Dixit, Associate Director, Haemato-oncology & Bone Marrow Transplant at Paras Health, Gurugram; and Dr. Atique Ahemad, Newborn & Child Specialist, Saifee Hospital, Mumbai to understand the complex burden of this disease and how parents and physicians can intervene early. STORY CONTINUES BELOW THIS AD How sickle cell affects the brain — often without warning According to Dr. Shweta Bansal, sickle cell disease significantly increases the risk of both overt and silent strokes in children. 'Due to the sickle-shaped red blood cells, the brain's blood vessels can get blocked, depriving areas of the brain of oxygen. About 10% of children with SCD experience a stroke by age 14,' she said. Yet the bigger threat may be silent strokes which occur in nearly 1 in 4 school-age children with SCD. These don't show immediate symptoms but can impair memory, learning, attention and behaviour. 'We use Transcranial Doppler (TCD) ultrasounds to measure blood flow in the brain. If the velocity is high, it indicates stroke risk and we start preventive therapy. MRIs also help identify silent strokes,' Dr. Bansal added. Early signs and complications in children Dr. Atique Ahemad said that while infants with SCD may remain asymptomatic in the first 6–7 months due to protective fetal haemoglobin, symptoms emerge soon after. These include pallor, delayed growth, hand-foot swelling (dactylitis), and frequent pain episodes. 'Children often cry excessively due to pain. These crises can start by the age of six and affect various body parts, arms, legs, back and chest leading to long-term damage,' he says. Pain crises, or vaso-occlusive crises (VOCs), are particularly harmful. Dr. Gaurav Dixit said that each episode deprives vital organs of oxygen, progressively damaging the kidneys, brain, lungs, liver and heart. 'Frequent VOCs significantly increase the risk of chronic organ dysfunction, stroke, pulmonary hypertension, and early mortality,' he warned. How pain and infections are managed Pain in SCD isn't just distressing — it's also diagnostically challenging. 'There is no scan to quantify pain. The patient's words are the only reliable indicator,' Dr. Ahemad said, emphasising the need for compassionate and responsive care. Dr. Bansal outlines a two-pronged strategy: preventing crises and managing acute attacks. Preventive measures include hydration, avoiding extreme temperatures, and reducing physical or emotional stress. For mild pain, paracetamol or ibuprofen suffices but severe cases may require hospital-based morphine treatment. Preventing infections is equally critical, as SCD weakens the spleen. Dr. Bansal advises routine handwashing, safe food hygiene, vaccinations (including annual flu and pneumococcal vaccines), and daily penicillin till age 5 for high-risk children. 'With regular check-ups and support, these children can lead full lives,' she says. Hydroxyurea: A gamechanger in disease management One of the most effective tools in managing SCD is hydroxyurea. Dr. Bansal explains: 'It helps produce more fetal haemoglobin, reducing red cell sickling. This means 50–70% fewer pain crises, fewer transfusions, better school attendance and significantly extended life expectancy, even in rural areas.' Importantly, she said that hydroxyurea is safe for long-term use, including in children older than 9 months. Bone Marrow Transplant: A potential cure — for a few While hydroxyurea helps manage symptoms, a bone marrow transplant (BMT) remains the only proven cure. However, it is only an option for a select group of patients. 'Children below 16 with a perfectly matched sibling donor and severe SCD complications — like stroke, lung disease, organ damage, or frequent crises — are considered eligible,' said Dr. Bansal. BMT carries risks and is generally reserved for the most severely affected cases. Research is ongoing into alternatives such as half-matched donors and gene therapies. STORY CONTINUES BELOW THIS AD Hidden organ damage and long-term risks Dr. Dixit reiterates the toll VOCs take on the body over time. 'Organ systems, kidneys, heart, lungs and brain deteriorate silently with each crisis. Chronic kidney disease, pulmonary hypertension, and heart failure are major causes of reduced life expectancy in adult SCD patients,' he said. Dr. Ahemad lists stroke, acute chest syndrome, retinal damage, and splenic or hepatic sequestration among the most severe complications seen in adults. 'Long-term pain, bone necrosis and arthritis are common too. Early management of VOCs is key to preserving organ health and improving life quality,' he advised.