
Measles 'out of control,' experts warn, as Alberta case counts surpass 1,000
Alberta's measles outbreaks have now eclipsed the 1,000-case mark and infectious disease specialists are warning the virus is "impossible to contain," given the current level of transmission.
The province reported another 24 cases on Friday, including 14 in the north zone, nine in the south and one in the Edmonton zone.
This brings the total confirmed cases since the outbreaks began in March to 1,020.
"It is a very grim milestone," said Dr. Karina Top, a pediatric infectious disease physician at the Stollery Children's Hospital in Edmonton, which has been treating children with measles.
"I'm very worried we're going to see more hospitalizations and some deaths soon because we know the death rate is about one to two per thousand. So it's likely that we're going to see that and that will be a very tragic day."
Measles is highly contagious and can lead to serious complications including pneumonia, brain inflammation — which can trigger seizures, deafness and brain damage — as well as premature delivery.
A premature baby who was born with measles died in Ontario recently. And another young child died of measles in that province last year.
Doctors warn there are severe long-term consequences as well, including immune system impacts and a degenerative neurological condition that occurs seven to ten years after an initial measles infection. It is rare but nearly always fatal.
'Out of control'
Alberta's case count has more than doubled in the last month. On May 20, a total of 486 cases had been confirmed.
"This is out of control," said Top.
The hardest hit areas are the south, central and north zones, where there are some very low vaccination rates among young children.
Case counts have been rising quickly in the north zone, which has now topped 200 cases. The south zone has confirmed 681 cases and the central zone has 105.
And health officials are warning the virus is more widespread in those areas than case counts reflect.
"Due to the number of people in these areas who may not be immune to measles, it's likely that some cases are going undetected or unreported," the Alberta government's measles web page states.
"I think we really need to be doing everything we can to engage with those communities that are affected and community leaders to see how best we can work with them to try to get people vaccinated to help contain this infection," said Top.
"And [we need to] get everyone else up to date so that if there are other cases introduced in Edmonton, Calgary or elsewhere in the province, it can be contained more quickly."
University of Calgary infectious disease physician Dr. Dan Gregson is also worried about Alberta's surging measles cases.
"This transmission is just out of the box. It's impossible to contain at the present time," he said.
"The risk, right now, of your child getting measles in Alberta if they're not immunized is pretty high."
Gregson is urging parents who have opted not to immunize their children to rethink that decision.
"If you had made a decision not to vaccinate because measles was not circulating, that's no longer true. We don't have herd immunity. There's measles circulating in the community. And the best way to prevent your child from having a complication would be to get them vaccinated," he said.
The vast majority of Alberta's measles cases are among the unimmunized.
The most recent data shows 85 Albertans have been hospitalized due to this year's outbreaks, including 14 who have ended up in intensive care.
"Most of these hospitalizations are due to patients having pneumonia — they're short of breath, they have to wear oxygen. Some of them are due to brain inflammation. [It's] not a pleasant thing for the parents or the child to have to go through," said Gregson.
In Edmonton, where the Stollery Children's Hospital is treating the sickest patients from northern Alberta, Top said the outbreaks are taking a toll.
"It is distressing as a pediatrician to see children that are sick from a disease that is completely vaccine preventable."
Hashtags

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles


CBC
2 hours ago
- CBC
Sask. NDP and ALS society calling on province to investigate Moose Jaw health centre
Social Sharing Saskatchewan's Opposition NDP and the province's ALS society are calling on Minister of Health Jeremy Cockrill to launch an investigation into the Dr. Goodenowe Restorative Health Center in Moose Jaw. Last week, the CBC reported that Dr. Dayan Goodenowe, who runs the centre, tells patients with ALS that his supplements can stop and reverse the progress of the disease. On his YouTube account, he says, "stopping the progression of ALS actually isn't that hard." He backs up his claim by pointing to some patients who say they feel better on his supplements. He also told CBC he's working on studies to verify their effectiveness. Goodenowe charges ALS clients $75,000 US for his three-month live-in treatment program. In CBC's story, some patients who took part said it did nothing to improve their condition. The NDP and the ALS Society say there's no published scientific evidence to back up Goodenowe's claims. They say all of the science indicates ALS is a death sentence. They said businesses should not be allowed to prey on vulnerable people. "We're talking about people with an incurable disease, who are desperate for hope, being misled with promises that are not backed in any scientific evidence. This is false hope being sold for profit," NDP rural and remote health critic Jared Clarke said at a news conference Friday. "We cannot allow unregulated facilities to target vulnerable people with misleading claims without any oversight or accountability. So today we are urging Minister Cockrill to act." Denis Simard, executive director of the ALS Society of Saskatchewan, echoed that call at the news conference, saying "we would invite the ministry to do a special investigation." Simard made a similar request months ago. In a Feb. 12 letter, he asked Cockrill to look into Goodenowe's business and "take appropriate action to prevent the dissemination of false medical information that could exploit those facing ALS." 'It is a private business' Cockrill refused CBC's request for an interview. In a written statement, he indicated there's nothing the provincial government can do because Goodenowe's centre, "has no ties to the Saskatchewan health care system." In interviews with CBC, Goodenowe regularly emphasized that he is not a medical doctor and his facility does not offer medical treatments or services. He has a Ph.D in Medical Sciences with an emphasis in psychiatry from the University of Alberta. "It is a private business, not a provincially regulated health centre or affiliate," Cockrill wrote. "The individual operating it is not a licensed medical doctor, so he does not fall under any established health regulatory body." Clarke said that if Cockrill is accurately describing the situation, that's an even stronger reason for him to do something. "To me that's why an investigation is important, to be able to assess whether there is a gap here [and] whether we need additional legislation," Clarke said. Simard agreed. "OK, we don't have an actual place in the law that allows us to investigate this. Let's create one," he said. "Let's find a way that's going to allow us to protect the most vulnerable in our province." In its research, CBC was directed to section 80 of Saskatchewan's Medical Profession Act, 1981, which seems to indicate that it is against the law in the province for someone who is not a registered medical professional to offer medical services. It says it's an offence in Saskatchewan if someone, "for hire, gain or hope of reward (i) engages in, professes to engage in or advertises to give advice in any aspect of practice; or (ii) furnishes any medicine or treats any disease or ailment by medicine, drugs or any form of treatment, influence or appliance." If found guilty of this offence, "and liable on summary conviction," the offender would be subject to a fine of up to $5,000. CBC asked the minister if this law might apply in this case. He didn't respond to the question. Goodenowe expanding operations In his written statement, the minister added that "we are not aware of any Saskatchewan residents living with ALS who have accessed Mr. Goodenowe's services." He didn't explain why he made that point. Simard noted that in CBC's story, the ALS patients were all from the United States. "These are all people that are being harmed by this process and I think we have a right to protect them," Simard said. He said this question is not going to go away for the provincial government, because Goodenowe is planning to expand his operations in Moose Jaw. In April, Goodenowe announced the Moose Jaw Vitality Project, which his website describes as "a $100 million community health initiative providing free access to cutting-edge health services and monitoring technologies for all residents of Moose Jaw, Saskatchewan." The project is planned to involve five facilities, including the restorative health centre, a cafe and a facility that will manufacture Goodenowe's supplements, which he has manufactured in the United States until now. Simard said Moose Jaw city council should be paying attention to this as well. "Let's make sure that this person has no approvals moving forward, so that until this is fully investigated, until we can fully validate what is being done by this individual, nothing should happen at any other level," he said. For his part, Simard said he has warned Saskatchewan's 73 ALS patients that they should have nothing to do with Goodenowe or his facility.


CBC
4 hours ago
- CBC
Are you living next to a toxic ‘forever chemical' hotspot?
You've probably heard about the health risks of toxic 'forever chemicals' — also known as per- and polyfluoroalkyl substances (PFAS). CBC News mapped out at least 80 sites across Canada where there could be risk of contamination.

CTV News
4 hours ago
- CTV News
Woman off insulin for Type 1 diabetes after a single dose of experimental manufactured stem cells
Amanda Smith celebrates the day, August 1, nearly two years ago, when she stopped taking insulin to manage her type one diabetes, just a few months after getting a dose of experimental stem cells as part of a study. 'I remember, like, being scared and excited, and it's history now,' she said. The 36-year-old nurse and mother is part of a small, but what some call 'milestone study,' of patients with Type 1 Diabetes using manufactured stem cells, designed to grow in the liver and become the full array of islet cells array of pancreatic islet cells that naturally control blood sugar levels. In a study published in the New England Journal of Medicine, researchers report that of the 12 patients who received a single dose of the stem cells, it eliminated the need for insulin in 10 for at least a year and stopped episodes of low blood sugar, or hypoglycemia, which can lead to dangerous complications, even death. For Amanda, the treatment has been a blessing. Diagnosed with late-onset juvenile diabetes when she was 25, she was plagued with sudden bouts of low blood sugar, or hypoglycemia that would leave her faint, despite close monitoring. The risk was a diabetic coma or worse. 'I get emotional because I'm free from those handcuffs ... I don't have that looming over me every day,' she said from her home in London, Ont. 'I took it as a death sentence,' she said. 'I knew, eventually, like the end is always some sort of complication with diabetes,' she said 'We've ... dealt with a lot of patients that have struggled with diabetes. And to be able to see such a transformational change in their life is just amazing,' said Dr. Trevor Reichman, the lead author and the Surgical Director of the Pancreas and Islet Cell Transplant Program at the University Health Network in Toronto. Dr. Trevor Reichman Dr. Trevor Reichman appears for an interview with CTV News. Reichman says it is the first time that scientists have seen this kind of response with implanted stem cell-derived islets. Vertex, a Boston-based biotech company that sponsored the study, derived the cells from embryonic tissue and then found a way to grow them stem cells in large quantities. Researchers, working at centers in the U.S. and at least three transplant hospitals in Canada, infused them into the patient's liver. Over the next four to six months, Reichman said they transformed into the array of hormone-producing cells found in a normal pancreas, and they were monitoring the patients' blood sugar levels in real time. 'In the liver, they're sensing a patient's blood glucose level, and they're secreting the appropriate hormone,' said Reichman. adding that these biological replacements appear to sense changes in 'seconds or milliseconds. Essentially, it's the same as your native islet cells would function.' 'I think the data is just so very exciting, so very, very powerful,' said Dr. Peter Senior, director of the Alberta Diabetes Institute at the University of Alberta. He was not part of this study. 'The primary objective of the study was just to show that the blood sugars were better and that people were not having severe hypoglycemia. They blew past that. Ten of the 12 people are off insulin,' said Senior. ' It's never been done before in history' said Dr. Michael Thompson, director of Vancouver General Diabetes Centre. 'It's first time they a have achieved a high enough levels of insulin in patients,'using a stem cell product 'It's a big advance' he added. But there's a tradeoff. The patients, however, require immune-suppressing drugs for life, so that the immune system doesn't destroy the cells. There are risks to these immunosuppressive medications, including a higher risk of some cancers, infections, and high blood pressure. Amanda says it is nothing like her constant terror that she might slip into a sudden diabetic coma. 'Taking a couple of pills three times a day is nothing. I take it with breakfast, lunch, and dinner. It's easy. No comparison, none,' she said. 'And I know it's a huge relief for my family, especially my husband, that's for sure.' The study also reports that two patients in the study died, one likely as a result of complications from that immunosuppression, which Dr. Reichman says underscores the need for patients to be closely monitored at experienced transplant centers. A second patient, according to the study, died of severe dementia. Off-the-shelf live cell therapy The idea of using cells implanted in the body to produce insulin, instead of insulin injections, began in Canada 25 years ago. Researchers in Alberta pioneered the Edmonton Protocol. It uses insulin-producing islet cells removed from diseased organ donors that are implanted into those with hard-to-manage Type 1 Diabetes. Some 2,500 patients have been treated around the world, according to the University of Alberta, which reports 80 per cent were able to stop taking insulin injections for a median time of 95 days. Stem cells pipettes (Image credit: Vertex) But the number of procedures is limited because there aren't enough organ donors to meet the demand, and patients also require long-term immune suppression. So, there have been some two dozen companies around the world looking at other ways of getting manufactured islet cells to regulate blood sugar as a replacement for insulin. The Vertex cells, originally called VX-880, have been renamed Zimislecel. The Boston-based pharmaceutical company (says it is ramping up production, as it 'These are fresh, brand-new cells – they're not 60-year-old cells that have already had a life, and we're repurposing them,' said Senior, who works in Edmonton. It pushes the boundary of therapy forward because there is the potential to create a renewable source of insulin-producing cells instead of waiting for cells from deceased donors,' he added. 'I think we've got a treatment for diabetes where we are no longer constrained by organ donors,' said Senior. 'We've got potentially a limitless source of cells that could be used, and that is a massively huge step forward in terms of a cell therapy becoming a reality.' The next step is for someone to produce stem cells that don't require immune suppression, by either genetically engineering the cells or encapsulating them to make them invisible to immune attack. Several pilot studies are underway. It's a welcome advance, according to Senior. While insulin therapy has been a lifesaver for many since its discovery in Toronto by Banting and Best in 1921, it's never been a cure. Stem Cells (Image credit: Vertex) 'I think people with diabetes deserve some of the transformative treatments we've seen in cancer and other diseases but we've been stuck essentially doing the same thing for 100 years,' said Senior. In Canada, there are some 300000 people with Type 1 diabetes. Thirty-two new cases are diagnosed each day. The number of new cases per year increased by 34 per cent between 2000 and 2022, according to Breakthrough TD1(formerly the Juvenile Diabetes Foundation of Canada). Unlike Type 2 diabetes, which is linked to environmental, dietary, and genetic factors, the exact cause of Type 1 diabetes is still unknown, but doctors say the immune system mistakenly attacks insulin-producing islet cells in the pancreas, resulting in a gradual decline in the availability of insulin to regulate blood sugar. Questions remain The study is being continued to include a total of 50 patients, in Vancouver, Edmonton, Toronto and the U.S., with Dr. Reichman's team actively recruiting candidates. There are still many questions. Dr. Reichman admits that no one knows how long these implanted cells will last. Amanda hasn't required any insulin inections for almost two years, the longest documented period so far. He adds there are no signs that the other nine, who also went off insulin, have gone back on the injections since their stem cell infusion. Unclear also is whether this therapy will reduce the longer-term and burdensome complications of diabetes, including heart problems, amputations, kidney failure, and vision loss. However, data from patients treated with the Edmonton protocol, using tissue from deceased donors, show signs of reduced complications, a promising sign for the newer therapy, according to Dr. Thompson. The other concern is that not all patients with severe hypoglycemia may want to make the same choice as Amanda, swapping the diabetes risks for those that come with the anti-rejection medications. 'Taking a couple of pills three times a day is nothing. It's easy. There's no comparison, none,' she said. Another question is that a single treatment therapy for this disease could come with a very high price tag. 'We'll have to wait and see,' said Reichman. Amanda Smith, meanwhile, tries to enjoy her freedom with her family and her work at a long-term care home, without thinking too far ahead. 'What happens if the cells stop working or something? You know, I just try and live right now, and I feel so blessed.' She debates the question - does she have diabetes anymore? 'I don't take any insulin anymore. I don't take medication for diabetes anymore. So, I feel like a regular person again without diabetes.'