
Scientists have found a breakthrough in cancer treatment, and it is deep within the ocean
Scientists at the University of Mississippi have made a significant discovery. They found a rare sugar in sea cucumbers. This sugar shows potential in stopping cancer spread. The compound blocks an enzyme cancer cells use to grow. Unlike other inhibitors, it does not affect blood clotting. Researchers are working to synthesize the compound for further testing.
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Safe for human use
Lack of abundance
A team of scientists led by the University of Mississippi has discovered a rare sugar in sea cucumbers that may help stop cancer from spreading, without the dangerous side effects of traditional treatments.The study published in the journal Glycobiology reveals that a compound called fucosylated chondroitin sulfate, found in the sea cucumber Holothuria floridana, blocks Sulf-2, an enzyme that cancer cells use to grow and metastasize. The compound could become a critical tool in future cancer therapies.'Marine life produces compounds with unique structures that are often rare or not found in terrestrial vertebrates,' said Marwa Farrag, a fourth-year doctoral student and lead author of the study. 'The sugar compounds in sea cucumbers are unique. They aren't commonly seen in other organisms. That's why they're worth studying.'Sulf-2 plays a key role in altering glycans, sugar molecules that coat the surface of all human cells and regulate communication and immune responses. When this enzyme modifies glycans, it helps cancer cells break away and spread. Blocking Sulf-2 may stop tumors from invading healthy tissues.'This sugar essentially stops the pruning of the cellular 'forest,'' said Dr. Vitor Pomin, associate professor of pharmacognosy. 'If we can inhibit that enzyme, we are fighting against the spread of cancer.'The research team, which also included scientists from Georgetown University, used lab testing and computer modeling to confirm the sugar's effect. Both methods produced consistent results.Unlike some Sulf-2 inhibitors already known, this sea cucumber sugar does not affect blood clotting, making it safer for use in humans. 'If a molecule interferes with blood coagulation, you risk life-threatening bleeding,' said Dr. Joshua Sharp, associate professor of pharmacology. 'This one doesn't.'The team now faces a new challenge: sea cucumbers aren't abundant enough to harvest for mass production. 'One of the problems in developing this as a drug would be the low yield,' said Dr. Pomin. 'So, we have to develop a chemical route.'The scientists are currently working to synthesize the compound in the lab so it can be tested in animal models.If successful, this breakthrough could pave the way for cleaner, safer, and more sustainable cancer treatments, originating not from synthetic chemicals or land animals, but from the ocean floor.
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Economic Times
9 hours ago
- Economic Times
Scientists have found a breakthrough in cancer treatment, and it is deep within the ocean
Scientists at the University of Mississippi have made a significant discovery. They found a rare sugar in sea cucumbers. This sugar shows potential in stopping cancer spread. The compound blocks an enzyme cancer cells use to grow. Unlike other inhibitors, it does not affect blood clotting. Researchers are working to synthesize the compound for further testing. Tired of too many ads? Remove Ads What does the discovery say? Tired of too many ads? Remove Ads Safe for human use Lack of abundance A team of scientists led by the University of Mississippi has discovered a rare sugar in sea cucumbers that may help stop cancer from spreading, without the dangerous side effects of traditional study published in the journal Glycobiology reveals that a compound called fucosylated chondroitin sulfate, found in the sea cucumber Holothuria floridana, blocks Sulf-2, an enzyme that cancer cells use to grow and metastasize. The compound could become a critical tool in future cancer therapies.'Marine life produces compounds with unique structures that are often rare or not found in terrestrial vertebrates,' said Marwa Farrag, a fourth-year doctoral student and lead author of the study. 'The sugar compounds in sea cucumbers are unique. They aren't commonly seen in other organisms. That's why they're worth studying.'Sulf-2 plays a key role in altering glycans, sugar molecules that coat the surface of all human cells and regulate communication and immune responses. When this enzyme modifies glycans, it helps cancer cells break away and spread. Blocking Sulf-2 may stop tumors from invading healthy tissues.'This sugar essentially stops the pruning of the cellular 'forest,'' said Dr. Vitor Pomin, associate professor of pharmacognosy. 'If we can inhibit that enzyme, we are fighting against the spread of cancer.'The research team, which also included scientists from Georgetown University, used lab testing and computer modeling to confirm the sugar's effect. Both methods produced consistent some Sulf-2 inhibitors already known, this sea cucumber sugar does not affect blood clotting, making it safer for use in humans. 'If a molecule interferes with blood coagulation, you risk life-threatening bleeding,' said Dr. Joshua Sharp, associate professor of pharmacology. 'This one doesn't.'The team now faces a new challenge: sea cucumbers aren't abundant enough to harvest for mass production. 'One of the problems in developing this as a drug would be the low yield,' said Dr. Pomin. 'So, we have to develop a chemical route.'The scientists are currently working to synthesize the compound in the lab so it can be tested in animal successful, this breakthrough could pave the way for cleaner, safer, and more sustainable cancer treatments, originating not from synthetic chemicals or land animals, but from the ocean floor.


Time of India
14 hours ago
- Time of India
Scientists have found a breakthrough in cancer treatment, and it is deep within the ocean
A team of scientists led by the University of Mississippi has discovered a rare sugar in sea cucumbers that may help stop cancer from spreading, without the dangerous side effects of traditional treatments. What does the discovery say? The study published in the journal Glycobiology reveals that a compound called fucosylated chondroitin sulfate, found in the sea cucumber Holothuria floridana, blocks Sulf-2, an enzyme that cancer cells use to grow and metastasize. The compound could become a critical tool in future cancer therapies. Play Video Pause Skip Backward Skip Forward Unmute Current Time 0:00 / Duration 0:00 Loaded : 0% 0:00 Stream Type LIVE Seek to live, currently behind live LIVE Remaining Time - 0:00 1x Playback Rate Chapters Chapters Descriptions descriptions off , selected Captions captions settings , opens captions settings dialog captions off , selected Audio Track default , selected Picture-in-Picture Fullscreen This is a modal window. Beginning of dialog window. Escape will cancel and close the window. Text Color White Black Red Green Blue Yellow Magenta Cyan Opacity Opaque Semi-Transparent Text Background Color Black White Red Green Blue Yellow Magenta Cyan Opacity Opaque Semi-Transparent Transparent Caption Area Background Color Black White Red Green Blue Yellow Magenta Cyan Opacity Transparent Semi-Transparent Opaque Font Size 50% 75% 100% 125% 150% 175% 200% 300% 400% Text Edge Style None Raised Depressed Uniform Drop shadow Font Family Proportional Sans-Serif Monospace Sans-Serif Proportional Serif Monospace Serif Casual Script Small Caps Reset restore all settings to the default values Done Close Modal Dialog End of dialog window. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Play War Thunder now for free War Thunder Play Now Undo 'Marine life produces compounds with unique structures that are often rare or not found in terrestrial vertebrates,' said Marwa Farrag, a fourth-year doctoral student and lead author of the study. 'The sugar compounds in sea cucumbers are unique. They aren't commonly seen in other organisms. That's why they're worth studying.' Sulf-2 plays a key role in altering glycans, sugar molecules that coat the surface of all human cells and regulate communication and immune responses. When this enzyme modifies glycans, it helps cancer cells break away and spread. Blocking Sulf-2 may stop tumors from invading healthy tissues. Live Events 'This sugar essentially stops the pruning of the cellular 'forest,'' said Dr. Vitor Pomin, associate professor of pharmacognosy. 'If we can inhibit that enzyme, we are fighting against the spread of cancer.' The research team, which also included scientists from Georgetown University, used lab testing and computer modeling to confirm the sugar's effect. Both methods produced consistent results. Safe for human use Unlike some Sulf-2 inhibitors already known, this sea cucumber sugar does not affect blood clotting, making it safer for use in humans. 'If a molecule interferes with blood coagulation, you risk life-threatening bleeding,' said Dr. Joshua Sharp, associate professor of pharmacology. 'This one doesn't.' Lack of abundance The team now faces a new challenge: sea cucumbers aren't abundant enough to harvest for mass production. 'One of the problems in developing this as a drug would be the low yield,' said Dr. Pomin. 'So, we have to develop a chemical route.' The scientists are currently working to synthesize the compound in the lab so it can be tested in animal models. If successful, this breakthrough could pave the way for cleaner, safer, and more sustainable cancer treatments, originating not from synthetic chemicals or land animals, but from the ocean floor.


Business Standard
05-06-2025
- Business Standard
The Black Patch Phenomenon: How People Release Up To 13 Pounds of 'Toxic Weight' in 30 Days
India PR Distribution New Delhi [India], June 5: Tired? Stressed? Fatigued? You are not alone - our lifestyles are extremely taxing on our bodies and minds alike. Headaches, bad sleep and stress are the unfortunate hallmarks of fast-moving modern life. Active ingredients that are found in the Nuubu foot patch are known for their ability to remove accumulating harmful elements from your body, which can greatly improve your sense of wellbeing! * Traditional Medicine gets Modern Upgrade According to Japanese traditional knowledge, the human body has over 360 acupuncture points, with more than 60 points found on the soles of the foot. Nuubu combines tried-and-true Asian techniques with a sleek and modern approach - attach the herbal-remedy based patches to your feet and wait a few hours for the toxin removal through your sweat glands. It has never been that easy! One of our top editors, Dennis, seemed to have it all - Georgetown University graduate, successful career, perfect relationship. But behind closed doors, he was fighting a battle that nearly destroyed his life. "I was gaining weight despite eating healthy, my back pain was unbearable, and I looked 10 years older than my actual age," Dennis recalls. "The worst part? Not a single doctor could tell me why." The Invisible Enemy At The Root Cause What Dennis didn't know was that his body had been quietly accumulating what leading Japanese researchers have identified as "metabolic waste" - hardened deposits of environmental toxins and cellular debris that studies suggest can contribute to up to 25-30 pounds of stubborn weight gain and may be linked to widespread inflammation throughout the body. "By age 45, the average person's body has potentially accumulated enough toxins to fill a small jar," explains renowned detoxification expert Dr. Tanaka Hiroshi, whose groundbreaking research would eventually transform Dennis's life. "These toxins aren't merely passive substances - research indicates they can actively interfere with cellular metabolism, potentially trigger systemic inflammation, and are believed to accelerate the visible signs of aging by up to 1.5x the normal rate." In The Past This Was Considered Magical It was something that's still used to this day. Just like your grandmother may have had miraculously effective natural cold remedies, people in Japanese villages still trust in ancient ways that work. People used to think it's magic... Now we know exactly how it works. A breakthrough fusion of advanced tourmaline crystal and centuries-old Japanese botanical wisdom that studies suggest can begin transforming your health in as little as 6 hours. Here's What Studies On These Ingredients Reveal Laboratory-grade tourmaline crystals generate an impressive 2000+ negative ions per second, creating a specialized electromagnetic field that research indicates may help dissolve and break down toxic accumulations in your bloodstream. Premium-grade Japanese bamboo vinegar, harvested at peak potency, is known to create a powerful osmotic effect that studies suggest can draw out up to 82% more heavy metals and environmental pollutants compared to standard detox methods. Houttuynia Cordata, a treasured medicinal herb in traditional Japanese medicine, is believed to enhance lymphatic drainage by up to 89%, while strategic placement over 60+ vital acupressure points creates what researchers call the "Cascade Effect" - potentially enhancing overall wellness by up to 73% Clinical studies show this unique combination can: -Reduce chronic pain by up to 67% in just 7 days - Release up to 13 pounds of toxic weight within the first month - Improve sleep quality by 82% - Reduce visible signs of aging by targeting inflammation at the cellular level The Transformation Begins After just one night using these revolutionary patches, Dennis was left speechless at his bathroom mirror. "The transformation of the patches was unlike anything I'd ever seen - they had changed from pristine white to pitch black. But what happened next left me truly stunned," he recalls. "When I stepped on the scale the next morning, not only did I feel lighter and more energized, but the numbers confirmed it - I was already 1,5 pounds lighter. The patches had turned black with toxins, and those toxins were no longer weighing me down." The Nuubu Difference: A Three-Phase Miracle The process begins the moment you apply the patches. During the first two hours, tourmaline crystals generate a powerful ionic field that penetrates deep into your tissue, breaking down hardened toxin clusters and awakening your body's natural detox pathways. This is why many users report feeling a gentle, warming sensation almost immediately. As you enter the deep extraction phase, which occurs between hours two and six, the Japanese herbs create what scientists call an "osmotic pull effect." This is when the real magic happens - toxins are drawn out through your newly activated foot pores, while fat cells begin releasing their stored toxins. Users often report waking up feeling lighter and more energized, even before completing the full eight-hour treatment. The final phase, cellular regeneration, is perhaps the most crucial. During these last two hours, your body enters an enhanced healing state. The captured toxins are neutralized, cells begin their natural repair processes, and energy pathways are cleared and optimized. This is why many users report looking in the mirror the next morning and seeing a noticeably younger reflection.