National Advertising Division Recommends Oral Essentials Discontinue 'Microbiome Safe' Claim for Lumineux Mouthwash

New York, NY , April 30, 2025 (GLOBE NEWSWIRE) — In a Fast-Track SWIFT challenge brought by competitor GuruNanda, LLC, BBB National Programs' National Advertising Division recommended that Oral Essentials, Inc. discontinue the claim that its Lumineux mouthwash products are 'Microbiome Safe.'
Fast-Track SWIFT is an expedited challenge process designed for single-issue advertising cases brought to the National Advertising Division (NAD).
To back its 'microbiome safe' claim, Oral Essentials submitted an in vitro study examining the effect of four mouthwash variants on five prominent species of bacteria linked to plaque, gingivitis, and cavities. The study reported the use of mouthwash did not decrease the population of any of the five strains of bacteria.
NAD found the in vitro study was not a good fit to support the challenged claim. In this study, only five out of the numerous species of bacteria in the mouth were tested, which is insufficient to support a claim that the product is safe for the entire microbiome.
NAD also questioned the in vitro study's real-world relevance to consumer use and noted that although the study concluded that there was '[n]o decrease' for every strain of bacteria tested, the numbers reveal that some strains did see a decrease in population.
NAD therefore concluded that Oral Essentials has not met its burden of providing a reasonable basis for the claim that its mouthwash products are 'Microbiome Safe' and recommended the challenged claim be discontinued.
In its advertiser statement, Oral Essentials stated, 'As a strong supporter of NAD, Oral Essentials will follow NAD's recommendations.'
All BBB National Programs case decision summaries can be found in the case decision library. For the full text of NAD, NARB, and CARU decisions, subscribe to the online archive. Per NAD/NARB Procedures, this release may not be used for promotional purposes.
About BBB National Programs: BBB National Programs, a non-profit organization, is the home of U.S. independent industry self-regulation, currently operating more than 20 globally recognized programs that have been helping enhance consumer trust in business for more than 50 years. These programs provide third-party accountability and dispute resolution services that address existing and emerging industry issues, create fair competition for businesses, and a better experience for consumers. BBB National Programs continues to evolve its work and grow its impact by providing business guidance and fostering best practices in arenas such as advertising, child-and-teen-directed marketing, data privacy, dispute resolution, automobile warranty, technology, and emerging areas. To learn more, visit bbbprograms.org.
About the National Advertising Division: The National Advertising Division (NAD) of BBB National Programs provides independent self-regulation and dispute resolution services, guiding the truthfulness of advertising across the U.S. NAD reviews national advertising in all media and its decisions set consistent standards for advertising truth and accuracy, delivering meaningful protection to consumers and promoting fair competition for business.
Disclaimer: The above press release comes to you under an arrangement with GlobeNewswire. Business Upturn takes no editorial responsibility for the same.

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• Yahoo

Hydration Room Expands to Rancho Cucamonga with New Wellness Clinic Focused on Proactive, Personalized Care

RANCHO CUCAMONGA, Calif., June 13, 2025 /PRNewswire/ -- Hydration Room, a leader in medically guided IV therapy and proactive wellness treatments, proudly announces the opening of its newest clinic at Victoria Gardens in Rancho Cucamonga marking its first location in San Bernardino County. This opening marks the next step in Hydration Room's statewide expansion, with multiple Bay Area clinics launching later this summer. "Rancho Cucamonga is a vibrant, growing community — the perfect place for Hydration Room to bring its wellness-first philosophy," said Michelle Mendoza, CEO of Hydration Room. "We're thrilled to support new patients in feeling their best and building sustainable, healthy routines." Far more than a hangover cure, Hydration Room offers IV and injection therapies designed to support energy, immunity, sleep, mood, fitness recovery, skin health, stress relief, and more. It's a personalized, medical-grade approach to feeling your best starting from the cellular level up. The clinic will also offer Hydration Room's newly launched NAD+ Membership, a monthly program designed to support long-term energy, mental clarity, and cellular health through consistent NAD+ therapy. "We're excited to bring our wellness-first model to Rancho Cucamonga," said Dr. Brett Florie, board-certified anesthesiologist and Founder of Hydration Room. "Our goal is to help patients take control of their health with personalized treatment plans, whether they're focused on recovery, longevity, or preventing burnout." Each patient begins with a complimentary consultation from a licensed Nurse Practitioner, who guides patients through tailored treatment plans based on their lifestyle and wellness goals. Whether you're rehydrating after travel, recovering from stress or illness, or investing in long-term vitality, Hydration Room offers a full menu of supportive therapies. To celebrate, a Grand Opening Celebration will be held on Saturday, June 28, 2025, and is open to the community. Guests will enjoy: Free B-12 shots Light bites Exclusive event-only offers RSVP to save your spot with the medical team for a B-12 shot. Founding Memberships are available now for the first 100 members, offering VIP access and 20% off monthly pricing. New patients can also enjoy 50% off their first treatment with promo code TRY50. The new clinic joins over 35 locations across Southern California, many of which feature private treatment rooms and a calming, physician-designed setting. To learn more or become a Founding Member, visit About Hydration RoomFounded in 2014 by board-certified anesthesiologist Dr. Brett Florie, Hydration Room is redefining modern wellness with personalized, physician-designed IV and injection therapy. With over 30 clinics across Southern California, Hydration Room blends medical expertise with a high-touch patient experience to deliver fast, effective treatments that support energy, immunity, recovery, longevity, and overall wellness. From NAD+ therapy to custom treatment plans guided by licensed medical professionals, Hydration Room empowers patients to take control of their health—starting at the cellular level. Media ContactTina McClellandVP View original content to download multimedia: SOURCE Hydration Room Sign in to access your portfolio

Associated Press

09-06-2025

• Associated Press

Niagen Bioscience Announces First-Ever Peer-Reviewed Study Highlighting the Potential of Nicotinamide Riboside (NR) for Werner Syndrome, a Rare Genetic Disorder

LOS ANGELES--(BUSINESS WIRE)--Jun 9, 2025-- Niagen Bioscience, Inc. (NASDAQ: NAGE) (formerly ChromaDex Corp.), the global authority on NAD+ (nicotinamide adenine dinucleotide) with a focus on the science of healthy aging, shares positive results from a clinical study published in the peer-reviewed journal Aging Cell, by a team led by Masaya Koshizaka, M.D., Ph.D., Associate Professor, and Koutaro Yokote, M.D., Ph.D., MBA, President of Chiba University, both of the Center for Preventive Medical Sciences, Chiba University, and the Department of Diabetes, Metabolism and Endocrinology, Chiba University Hospital, Japan. This is the first study to demonstrate the safety and efficacy of Niagen Bioscience's patented nicotinamide riboside (NR) ingredient, Niagen ®, in individuals with Werner syndrome (WS), a rare genetic disorder marked by rapid aging and premature mortality. 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In Ataxia Telangiectasia (AT), Niagen has shown improvements in neurological function, coordination, and immune markers, including in pediatric populations. Rob Fried, CEO of Niagen Bioscience, stated, 'Rare disease research is a priority for Niagen Bioscience, particularly those indications associated with accelerated aging, mitochondrial dysfunction, or NAD+ deficiency.' The U.S. Food and Drug Administration (FDA) previously granted Orphan Drug Designation (ODD) and Rare Pediatric Disease (RPD) Designation to NR for the treatment of AT. These designations underscore the urgent unmet need and potential therapeutic value of Niagen in rare disease populations. 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All forward-looking statements are qualified in their entirety by this cautionary statement and Niagen Bioscience undertakes no obligation to revise or update this release to reflect events or circumstances after the date hereof. View source version on CONTACT: Niagen Bioscience Media Contact: Kendall Knysch, Senior Director of Media Relations & Partnerships 310.405.5227 [email protected] Bioscience Investor Relations Contact: ICR, LLC Reed Anderson (646) 277-1260 Stephanie Carrington (646) 277-1282 [email protected] KEYWORD: NORTH AMERICA UNITED STATES ASIA PACIFIC EUROPE JAPAN CALIFORNIA INDUSTRY KEYWORD: RESEARCH VITAMINS/SUPPLEMENTS GENETICS CLINICAL TRIALS BIOTECHNOLOGY ALTERNATIVE MEDICINE HEALTH PHARMACEUTICAL SCIENCE SOURCE: Niagen Bioscience, Inc Copyright Business Wire 2025. PUB: 06/09/2025 08:32 AM/DISC: 06/09/2025 08:31 AM

Vogue

08-06-2025

• Vogue

A Longevity Expert's Guide to the Best NAD+ Supplements

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In This Article: Best Overall NAD+ Supplement: Tru Niagen Age Better NAD+ Tru Niagen Age Better NAD+ Supplement $49 AMAZON Why We Love It: Dr. Kahn recommends Tru Niagen for oral NAD+ supplementation because it is 'well-studied, third-party tested, and trusted for purity.' This supplement contains a patented ingredient called Niagen—which includes nicotinamide riboside (NR), a unique form of vitamin B3 and precursor to NAD+. NR is an efficient way to elevate NAD+ levels because it can penetrate the cell membrane directly. True Niagen's patented ingredient Niagen is also clinically studied for its safety and efficacy in over 35 peer-reviewed published research papers (which it conveniently lists out on its website). It partners with the best-in-class institutions like Mayo Clinic, Harvard, and more, and 90% of its studies are independently researched—meaning they're conducted or funded by a third-party. Dr. Kahn recommends Tru Niagen for oral NAD+ supplementation because it is 'well-studied, third-party tested, and trusted for purity.' This supplement contains a patented ingredient called Niagen—which includes nicotinamide riboside (NR), a unique form of vitamin B3 and precursor to NAD+. NR is an efficient way to elevate NAD+ levels because it can penetrate the cell membrane directly. True Niagen's patented ingredient Niagen is also clinically studied for its safety and efficacy in over 35 peer-reviewed published research papers (which it conveniently lists out on its website). It partners with the best-in-class institutions like Mayo Clinic, Harvard, and more, and 90% of its studies are independently researched—meaning they're conducted or funded by a third-party. Type: NR NR Dose: 2 capsules Best Vegan NAD+ Supplement: Pure Encapsulations NR Longevity Pure Encapsulations NR Longevity Supplement $60 AMAZON Why We Love It: Another favorite of Dr. Kahn, Pure Encapsulations uses the same patented NR complex (Niagen) developed by Tru Niagen. While more research needs to be done, some early trials showed initial evidence that supplementation with NR was safe in humans and could effectively boost NAD levels. It can be a powerful tool to support the health of your cells, heart, muscles, and more. Hypoallergenic, non-GMO, and gluten-free, this vegan capsule also contains broccoli sprout concentrate and trans-resveratrol to supercharge your supplement routine. Another favorite of Dr. Kahn, Pure Encapsulations uses the same patented NR complex (Niagen) developed by Tru Niagen. While more research needs to be done, some early trials showed initial evidence that supplementation with NR was safe in humans and could effectively boost NAD levels. It can be a powerful tool to support the health of your cells, heart, muscles, and more. Hypoallergenic, non-GMO, and gluten-free, this vegan capsule also contains broccoli sprout concentrate and trans-resveratrol to supercharge your supplement routine. Type: Nicotinamide riboside chloride Nicotinamide riboside chloride Dose: 2 capsules Best NAD+ Supplement for Performance: THORNE NiaCel 400 Why We Love It: Thorne is one of the most reputable brands known in the supplement industry. Powered by a unique form of NR that's exclusive to Thorne, it's a great choice for athletes or those looking for more robust NAD+ support, because every batch is NSF Certified for Sport and made without ingredients banned by many major athletic organizations. One dose is only one capsule, so it's also incredibly easy to work into your supplement routine. Thorne is one of the most reputable brands known in the supplement industry. Powered by a unique form of NR that's exclusive to Thorne, it's a great choice for athletes or those looking for more robust NAD+ support, because every batch is NSF Certified for Sport and made without ingredients banned by many major athletic organizations. One dose is only one capsule, so it's also incredibly easy to work into your supplement routine. Type: NR NR Dose: 1 capsule Best NAD+ Supplement With Polyphenols: Elysium Basis NAD Plus Supplement Elysium Basis NAD Plus Supplement $60 AMAZON Why We Love It: With both NAD+ precursor nicotinamide riboside and pterostilbene (PT), a powerful plant polyphenol, this supplement helps boost your cellular energy to protect your cells from the wear and tear we experience from modern life. 'Alcohol, smoking, overeating, stress, environmental toxins are some things that can speed up the decline of NAD+,' says Hamdan. 'There are ways to rebuild those levels both naturally and with a little help.' Polyphenols are also said to help restore NAD+ levels, so we love that this capsule packs a two-for-one punch. The brand also offers a 30-day risk-free trial, so you can try the supplement and if you don't love it, you can get a full refund. With both NAD+ precursor nicotinamide riboside and pterostilbene (PT), a powerful plant polyphenol, this supplement helps boost your cellular energy to protect your cells from the wear and tear we experience from modern life. 'Alcohol, smoking, overeating, stress, environmental toxins are some things that can speed up the decline of NAD+,' says Hamdan. 'There are ways to rebuild those levels both naturally and with a little help.' Polyphenols are also said to help restore NAD+ levels, so we love that this capsule packs a two-for-one punch. The brand also offers a 30-day risk-free trial, so you can try the supplement and if you don't love it, you can get a full refund. Type: NR NR Dose: 2 capsules Best NADH NAD+ Supplement: ProHealth Longevity NADH Pro ProHealth Longevity Longevity NADH Pro Supplement $39 $37 AMAZON Why We Love It: For mood, memory, energy, and focus support, these lozenges taste like lemon and easily dissolve under your tongue. It uses NADH—NAD+ is an oxidized form of nicotinamide adenine whereas NADH is a reduced form of nicotinamide adenine, meaning it gains the electron lost by NAD+— which is able to enter the cell via the membrane. Early research found that there is promise with oral NADH for treating chronic fatigue syndrome, with more clinical trials underway. For mood, memory, energy, and focus support, these lozenges taste like lemon and easily dissolve under your tongue. It uses NADH—NAD+ is an oxidized form of nicotinamide adenine whereas NADH is a reduced form of nicotinamide adenine, meaning it gains the electron lost by NAD+— which is able to enter the cell via the membrane. Early research found that there is promise with oral NADH for treating chronic fatigue syndrome, with more clinical trials underway. Type: NADH NADH Dose: 1 lozenge Best NAD+ Supplement With Resveratrol: Omre Nicotinamide Riboside + Resveratrol NAD Supplement Omre Nicotinamide Riboside + Resveratrol NAD Supplement $60 AMAZON Why We Love It: Not only does this capsule help boost NAD+ production in cells, the secret molecule to your best skin ever, by using precursor NR, it adds even more benefits with resveratrol. Resveratrol is a powerful antioxidant—found in grapes—best known for its research-backed health benefits (and the root of what we know as the 'French paradox.') 'I like NAD+ boosters stacked with other ingredients as I find that gives you the best results,' says Hamdan. The brilliance of the formula is not just what it's made with, but what it's made without—there are no fillers, artificial additives, or preservatives. Not only does this capsule help boost NAD+ production in cells, the secret molecule to your best skin ever, by using precursor NR, it adds even more benefits with resveratrol. Resveratrol is a powerful antioxidant—found in grapes—best known for its research-backed health benefits (and the root of what we know as the 'French paradox.') 'I like NAD+ boosters stacked with other ingredients as I find that gives you the best results,' says Hamdan. The brilliance of the formula is not just what it's made with, but what it's made without—there are no fillers, artificial additives, or preservatives. Type: NR NR Dose: 2 capsules Best Sublingual NAD+ Supplement: Renue by Science Nicotinamide Riboside Powder Renue by Science Nicotinamide Riboside Powder $109 $79 AMAZON Why We Love It: Not only is this powder manufactured in a GMP-compliant facility, the brand also puts every supplement through stringent third-party testing for quality assurance. It's great for those who are wary of taking pills and prefer to customize their supplement routine. It comes in a powder format, so you can put the zesty, citrus-flavored dust directly under your tongue, mix it in water, or blend it with your favorite beverage. The brand also prominently lists their certificate of analysis on their website, a major bonus for users who appreciate transparency. Not only is this powder manufactured in a GMP-compliant facility, the brand also puts every supplement through stringent third-party testing for quality assurance. It's great for those who are wary of taking pills and prefer to customize their supplement routine. It comes in a powder format, so you can put the zesty, citrus-flavored dust directly under your tongue, mix it in water, or blend it with your favorite beverage. The brand also prominently lists their certificate of analysis on their website, a major bonus for users who appreciate transparency. Type: NRC NRC Dose: 2 scoops Best Liposomal NAD+ Supplement: Rho Nutrition Liposomal NAD+ Rho Nutrition Liposomal NAD+ Supplement $56 AMAZON Why We Love It: Rho's liquid NAD+ is the ingestible answer to those who want a vitamin B3 boost without getting an expensive IV drip. With a tangy lemon flavor and a vegan, sugar-free, keto-friendly, non-GMO, gluten, dairy-free, and soy-free formulation, customers reported loving the ability to customize their daily dosage and beat the afternoon slump. Rho's liquid NAD+ is the ingestible answer to those who want a vitamin B3 boost without getting an expensive IV drip. With a tangy lemon flavor and a vegan, sugar-free, keto-friendly, non-GMO, gluten, dairy-free, and soy-free formulation, customers reported loving the ability to customize their daily dosage and beat the afternoon slump. Type: NAD NAD Dose: 4 milliliters Best Powder NAD+ Supplement: Timebeam Beauty Bounce Mode Healthy Pixie Timebeam Beauty Bounce Mode Healthy Pixie Supplement $49 TIMEBEAM BEAUTY Why We Love It: While NAD+ is the ingredient everyone is obsessing over, the truth is that NAD+ does not work by itself. Hamdan formulated this powder with NAD+ 'friends' like vitamin C, ribose, and rhodiola. 'This helps increase the efficacy and bioavailability of the NAD+,' says Hamdan. Hamdan also sought out an incredibly powerful and innovative NAD+ booster for this formula (we found it's a trademarked complex called RiaGev-WS), which she says is superior to NMN and NR. 'It's a direct source of NAD+, meaning it boosts not only NAD+ but two other longevity molecules in the cells called ATP and glutathione, while also decreasing cortisol levels,' says Hamdan. 'It's also easily absorbed by your body—remember if you don't absorb it, you can't use it.' The sprinkle-able, fast-melting powder melts right onto your tongue or can be mixed into hot or cold drinks which makes it one of the easiest ways to get your daily boost of NAD+. While NAD+ is the ingredient everyone is obsessing over, the truth is that NAD+ does not work by itself. Hamdan formulated this powder with NAD+ 'friends' like vitamin C, ribose, and rhodiola. 'This helps increase the efficacy and bioavailability of the NAD+,' says Hamdan. Hamdan also sought out an incredibly powerful and innovative NAD+ booster for this formula (we found it's a trademarked complex called RiaGev-WS), which she says is superior to NMN and NR. 'It's a direct source of NAD+, meaning it boosts not only NAD+ but two other longevity molecules in the cells called ATP and glutathione, while also decreasing cortisol levels,' says Hamdan. 'It's also easily absorbed by your body—remember if you don't absorb it, you can't use it.' The sprinkle-able, fast-melting powder melts right onto your tongue or can be mixed into hot or cold drinks which makes it one of the easiest ways to get your daily boost of NAD+. Type: RiaGev-WS RiaGev-WS Dose: 1 packet Best NMN NAD+ Supplement: Wonderfeel Youngr NMN Wonderfeel Youngr NMN Supplement $88 WONDERFEEL Why We Love It: With a patented blend of NMN, vitamin D, resveratrol, and olive antioxidant super ingredient hydroxytyrosol, this NAD+ supplement is ranked among the best of the best according to longevity experts. 'Oral precursors like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), are more easily absorbed and efficiently converted to NAD+ within cells,' says Kahn. There's also promising pre-clinical research that NMN has beneficial effects on cognitive function. The brand has an impressive list of medical advisors and scientific experts on board, including Harvard-, Yale-, and Columbia-trained Dr. Andrew Salzman, MD, who helped develop the formula. With a patented blend of NMN, vitamin D, resveratrol, and olive antioxidant super ingredient hydroxytyrosol, this NAD+ supplement is ranked among the best of the best according to longevity experts. 'Oral precursors like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), are more easily absorbed and efficiently converted to NAD+ within cells,' says Kahn. There's also promising pre-clinical research that NMN has beneficial effects on cognitive function. The brand has an impressive list of medical advisors and scientific experts on board, including Harvard-, Yale-, and Columbia-trained Dr. Andrew Salzman, MD, who helped develop the formula. Type: NMN NMN Dose: 2 capsules Everything You Need to Know