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AstraZeneca signs AI research deal with China's CSPC for chronic diseases

AstraZeneca signs AI research deal with China's CSPC for chronic diseases

Economic Times13-06-2025

AstraZeneca has signed an AI-led research agreement with China's CSPC Pharmaceutical Group worth up to $5.3 billion, which would help the Anglo-Swedish drugmaker develop therapies for chronic conditions, it said on Friday. The deal marks the latest effort by AstraZeneca to revive its business in China, its second-biggest market, where it has faced several challenges including the arrest of its China president last year and potential fines related to imports. Under Friday's agreement, the two companies will collaborate to discover and develop pre-clinical candidates, including a small molecule oral therapy for immunological diseases, with CSPC conducting AI-driven research in Shijiazhuang City.
"This strategic research collaboration underscores our commitment to innovation to tackle chronic diseases which impact over two billion people globally," AstraZeneca executive Sharon Barr said in a statement.
Friday's agreement follows AstraZeneca's announcement in March that it will invest $2.5 billion in a R&D hub in Beijing, and it also marks further investment in AI following collaborations with Immunai, Qure.ai and Tempus AI.
AstraZeneca will pay CSPC an upfront fee of $110 million. The Hong Kong-listed firm is also eligible to receive up to $1.62 billion for reaching development milestones and $3.6 billion linked to sales-related milestones, the groups said in separate statements.
They signed a licensing deal last October in which AstraZeneca agreed to pay up to $1.92 billion to CSPC to develop a candidate which would boost its cardiovascular pipeline. AstraZeneca and CSPC both have wide-ranging pipeline portfolios, including cancer treatments and those targeting cardiovascular diseases. However, about 80% of CSPC's total revenue comes from its finished drug segment, according Morningstar analysts. The Chinese group said last month it was in negotiations with third parties on new licensing and collaboration. Friday's agreement also gives AstraZeneca the rights to exercise options for exclusive licenses for candidates identified as part of the collaboration.

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Ringfencing India? After Pakistan and Afghanistan, now China holds a tri‑nation meet with Bangladesh. What it means
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Time of India

time35 minutes ago

  • Time of India

Ringfencing India? After Pakistan and Afghanistan, now China holds a tri‑nation meet with Bangladesh. What it means

China recently hosted Bangladesh and Pakistan for talks in Kunming. The meeting aimed to boost cooperation in trade and connectivity. A working group will explore joint projects. This follows a similar China-Pakistan-Afghanistan meeting. India is concerned about China's growing influence in the region. Security ties between Bangladesh, Pakistan, and China are also under scrutiny. Tired of too many ads? Remove Ads Why China, Bangladesh, Pak meeting matters for New Delhi What Pakistan, China, Bangladesh agreed in the meet Focus area Planned cooperation Economy & trade Joint projects in industry, digital economy and maritime logistics Connectivity Exploration of Belt and Road links—potentially an eastward spur of CPEC People's welfare Agriculture, climate action, health, education and youth exchanges Follow‑up A working group to translate the Kunming understandings into pilot projects Bangladesh's quiet pivot towards Pak, China Former Bangladesh military intelligence chief end 12-day China trip Tired of too many ads? Remove Ads Meeting comes after China, Afghanistan, Pakistan meet last month China on Thursday brought Bangladesh and Pakistan together for an inaugural trilateral dialogue in Kunming, barely a month after hosting a similar meeting with Pakistan and Afghanistan. The closed‑door talks, led by Chinese Vice‑Foreign Minister Sun Weidong, agreed to set up a working group for 'good‑neighbourly, equal and mutually trusted' cooperation, signalling Beijing's intent to knit India's neighbours more tightly into its strategic India, the move feeds a long‑running concern that China is cultivating a ring of friendly states along the subcontinent's periphery. New Delhi already objects to the China‑Pakistan Economic Corridor running through Pakistan‑occupied Kashmir. Now, with Bangladesh's interim leadership warming to Beijing—and exploring closer ties with Islamabad—the prospect of a three‑way framework on trade, infrastructure and security raises fresh questions about India's strategic Acting Foreign Secretary Ruhul Alam Siddique joined Sun at Kunming, while Foreign Secretary‑designate Amna Baloch represented Pakistan via video. The gathering came soon after Dhaka's Chief Adviser Muhammad Yunus publicly asked Beijing for economic help and discreetly revived contact with Islamabad—moves that have already drawn attention in New another development that has raised red flags within India's security establishment, Major General (Retd) Rezzakul Haider Chowdhury, former Bangladesh military intelligence chief and a convicted figure in the 2004 Chittagong arms smuggling case, reportedly concluded a 12-day trip to Guangzhou, China, on June 18. His visit coincided with that of Bangladesh's interim National Security Adviser Dr Khalilur Rahman, who reportedly sought Beijing's help to arrange a backchannel meeting with Pakistan's ISI chief. Indian agencies view this synchronised movement of high-level security actors—linked to past anti-India plots—as a signal of a deeper and potentially coordinated security alignment between Beijing, Islamabad, and follows a May meeting in which China, Pakistan and Afghanistan agreed to extend CPEC into Afghan territory. India had protested that any third‑country role in CPEC infringes on its sovereignty. The new Bangladesh‑Pakistan‑China line‑up suggests Beijing is applying the same template to India's eastern Thursday's statements highlighted 'true multilateralism' and insisted the talks were 'not directed at any third party', the meeting comes at a time of heightened tensions in South Asia:India's May strikes on terror camps in Pakistan and PoK, which prompted Beijing's vocal support for Islamabad.82 per cent of Islamabad's defence imports already come from agencies are probing reports that Dhaka's interim National Security Adviser has sought a Beijing‑brokered meeting with Pakistan's ISI chief.

AI didn't take the job. It changed what the job is.
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Mint

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AI didn't take the job. It changed what the job is.

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The work still exists, but it doesn't look like it used to. Doctors don't just rely on training—they rely on machines to catch what their fatigue might miss. Factory workers aren't lifting metal—they're supervising systems. Engineers aren't writing code—they're managing what the agents spit out. In some places, people are being lifted. In others, pushed out. This isn't about replacement. It's about redefinition. And not everyone is getting the chance to adapt. *** In Parbhani, Dr. Chaitanya isn't trying to be some AI-era pathologist. He just doesn't want to miss a sign of cancer again. He bought the scanner not because anyone sold him a pitch-deck future, but because he was tired. Because late at night, after hours of non-stop samples, the eyes slip. And he knows what that costs. The machine doesn't replace his judgment – it just doesn't lose focus when he does. In Jaipur, Wipro didn't automate Chandni out. They built the floor to fit her. 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ICICI Bank once wanted to acquire HDFC, Deepak Parekh spills the secret
ICICI Bank once wanted to acquire HDFC, Deepak Parekh spills the secret

Time of India

time2 hours ago

  • Time of India

ICICI Bank once wanted to acquire HDFC, Deepak Parekh spills the secret

Deepak Parekh revealed Chanda Kochhar's merger proposal between ICICI and HDFC, predating HDFC's reverse merger. Parekh cited regulatory pressure from the RBI as the primary driver for the HDFC-HDFC Bank merger, emphasizing the need for larger Indian banks. Post-merger, ICICI Bank has outperformed HDFC Bank in key metrics like profit growth and net interest margin. Tired of too many ads? Remove Ads Tired of too many ads? Remove Ads Tired of too many ads? Remove Ads Former HDFC chairman Deepak Parekh has revealed that former ICICI Bank chief Chanda Kochhar once proposed a merger between ICICI and HDFC, well before HDFC's reverse merger with its own banking a conversation with Kochhar on her YouTube channel, Parekh recounted, "I remember you talking to me once. I remember it very clearly. It's never been talked about in public, but I'm willing to share it now. You said that ICICI started HDFC. 'Why don't you come back home?' That was your offer."Parekh said he declined the offer at the time, saying it "won't be fair" or "proper with our name and the bank and all."Parekh described the eventual HDFC-HDFC Bank merger, completed in July 2023, as a move driven by regulatory compulsions rather than business ambition. The Reserve Bank of India had classified large NBFCs like HDFC, which then held assets exceeding ₹5 lakh crore, as systemically important — well above the ₹50,000-crore threshold."RBI supported us and they pushed us into it to some extent and they helped us," Parekh said. However, he added that there were "no concessions, no relief, no time, nothing."Parekh also said the deal had been executed with extreme confidentiality. 'It was kept a secret. No one knew about it—when it hit the press in the morning, that's when everyone found out. The government was aware because RBI was in touch with them, and we kept it so close—just lawyers, due diligence, accountants,' he on the conclusion of the merger, Parekh called it "a sad day and a happy day." He added, "It's good for the institution. It's good for the country to have large banks. Look at how large Chinese banks are. We have to be bigger, larger in India."On April 4, 2022, HDFC Bank announced its plan to acquire mortgage lender HDFC in a deal valued at about $40 billion, creating one of the largest financial institutions in Indian history. The merger gave rise to a banking entity worth $172 billion, affecting tens of millions of customers and shareholders across both companies, along with their group insurance and asset management said Indian banks must grow through acquisitions in order to become stronger in the also listed key concerns for chief executives, including continuing uncertainty in supply chains, trade policies, and export the insurance front, Parekh described it as the "least understood product" and criticised "mis-selling by banks" which, he said, was driven by the lure of high upfront HDFC Bank , in April this year, crossed the ₹15 lakh crore market capitalisation mark — an elite milestone — a quieter shift has been unfolding in the private banking space. ICICI Bank has steadily pulled ahead of HDFC Bank on several key performance Bank is now seen as a frontrunner among private sector lenders in India. HDFC Bank, meanwhile, has been navigating the after-effects of the 2023 merger, which have affected its growth FY25, ICICI Bank recorded profit growth of 15%, while HDFC Bank's profits rose by 11%. Both banks registered similar net interest income (NII) growth, but ICICI had a stronger net interest margin (NIM) of 4.41% compared with HDFC Bank's NIM of 3.65%.ICICI Bank also reported 14% growth in both advances and deposits for FY25. HDFC Bank, however, saw its advances grow at nearly half the pace of its merger added a substantial loan portfolio to HDFC Bank but did not bring in a matching level of deposits. This resulted in a spike in the loan-to-deposit ratio (LDR) to over 100% post-merger. Although HDFC Bank reduced this figure to 96.5% by the end of FY25, it still faces pressure to either increase deposits or slow down contrast, ICICI Bank's LDR stood at a healthier 82.4% as of March to the elevated LDR, HDFC Bank deliberately slowed down its credit expansion during FY25 to maintain balance. The bank's management believes that improving systemic liquidity will help raise deposits going forward.A high LDR suggests a bank is lending a large proportion of its deposits, which can become a risk if too many depositors withdraw funds at once and liquidity tightens.

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