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How We Chose the 2025 TIME100 Most Influential People in Health

How We Chose the 2025 TIME100 Most Influential People in Health

Yahoo08-05-2025

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A surprising sentence post-2020: This year is unlike any other in the history of global health. With the confirmation of anti-establishment leaders Robert F. Kennedy Jr., Dr. Marty Makary, and Dr. Jay Bhattacharya to the U.S.'s top health positions, President Donald Trump's withdrawal from the World Health Organization (WHO) and the defunding of USAID, health professionals are scrambling to understand whether their work can continue, and, if not, what will happen to patients. In a year of such upheaval, the TIME100 Health—100 people who are most influential in the world of health right now—looks a bit different.
A lot is happening.
To select these 100 individuals, our team of health correspondents and editors, led by Emma Barker Bonomo and Mandy Oaklander and with guidance of Dr. David Agus and Arianna Huffington, spent months consulting sources and experts around the world. The result is a community of leaders—scientists, doctors, advocates, educators, and policy-makers, among others—who are changing the health of the world.
There are pioneers, like Australian Prime Minister Anthony Albanese, who, stricken by the alarming statistics of the teen mental-health crisis, took on Big Tech to ban kids under 16 from social media in his country. And there are innovators, like Tomas Cihlar and Wesley Sundquist, who came up with Gilead's lenacapavir, a new way to treat HIV with only two shots per year.
Dr. Peter Lurie is a leader who, as president of the Center for Science in the Public Interest, has been lobbying to get cancer-linked synthetic food dyes out of our diets for decades, and, in January, finally succeeded with the banning of Red Dye No. 3 in U.S. foods. Princess Kate Middleton catalyzed a powerful conversation about rising cancer rates in young adults when she spoke out about her own diagnosis at age 42.
Then there are the titans, like World Health Organization (WHO) Director-General Tedros Adhanom Ghebreyesus, on the cover of this issue. Faced with losing its largest funder and most powerful member when the U.S. withdrew from the organization in January, Ghebreyesus is pivoting to make a more nimble WHO focused on establishing health independence in developing nations, while holding out hope for talks with President Trump. TIME spent time with Ghebreyesus at WHO headquarters in Geneva, where he spoke candidly about past mistakes and the path forward for global health.
Whether the individuals on this list are familiar or entirely new to you, the work they're doing is changing the lives of people in your community and around the globe. Later in May, TIME will gather the TIME100 Health members in New York City for an exchange of ideas about how to make a healthier world.
Contact us at letters@time.com.

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Administration to phase out NIH support of HIV clinical guidelines
Administration to phase out NIH support of HIV clinical guidelines

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Administration to phase out NIH support of HIV clinical guidelines

The National Institutes of Health's support for federal guidelines that steer the treatment of more than a million HIV patients in the United States will be phased out by next June, according to the agency's Office of AIDS Research, a move that troubled some doctors and raised questions about whether the guidelines themselves will change. It is unclear whether Health and Human Services Secretary Robert F. Kennedy Jr. plans to bring the guidance in line with his own controversial views about an infectious disease that 30 years ago was the leading cause of death for people 25 to 44 years old. The Office of AIDS Research, which is part of the National Institutes of Health, informed members of the panels responsible for the guidelines in a letter that, 'in the climate of budget decreases and revised priorities, OAR is beginning to explore options to transfer management of the guidelines to another agency within' HHS. 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Guidelines for HIV are divided into a half-dozen categories, including sets for adults/adolescents, pediatric patients, pregnant women and HIV patients who are displaced by natural disasters. The webpage listing the guidelines now says they are 'being updated to comply with Executive Orders,' raising the question of whether sections dealing with care for transgender people with HIV may be changed or eliminated. The letter sent to panel members did not say specifically if or how the clinical practice guidelines might change, only that 'Together, we now have an opportunity to develop a proactive, careful transition plan for each Panel.' The letter noted that 'a special session on guidelines sustainability planning' has been scheduled for Thursday with panel leadership and the Office of AIDS Research Advisory Council. Officials at NIH referred questions to the Department of Health and Human Services, which did not respond to emails requesting clarification of the letter. Kennedy has long espoused controversial views about HIV, suggesting that contrary to widely held medical belief, the virus was not the cause of AIDS. In a video posted on Twitter in 2023, Kennedy tells an audience, 'A hundred percent of the people who died at first, the first thousand who had AIDS, were people who were addicted to [a class of drugs called] poppers. … They were people who were part of a gay lifestyle. They were burning the candle at both ends, and they were taking a lot of injectable drugs.' Under Kennedy, HHS has terminated hundreds of millions of dollars in HIV-related research grants. The department closed its Office of Infectious Diseases & HIV Policy that coordinated the federal response to the virus. At the same time, the Centers for Disease Control and Prevention lost staff in its HIV prevention division who conducted studies and surveillance, ran health campaigns and supported local prevention programs. 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RFK Jr. dismissing experts creates deadly vaccine hesitancy
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RFK Jr. dismissing experts creates deadly vaccine hesitancy

Kennedy has long planted the seeds of vaccine hesitancy, despite evidence that contradicts his falsehoods. Now we are once again seeing more children succumb to vaccine-preventable diseases. Since 1964, pediatricians have looked to the Advisory Committee on Immunization Practices to provide evidence-based recommendations regarding childhood vaccines. We represent more than 80 years of experience as pediatricians in Nashville and have benefitted from ACIP throughout our careers. On June 9, our clinic days were disrupted by the news that Health and Human Services Secretary Robert F. Kennedy Jr. had dismissed all 17 ACIP members. These members are academic clinicians, epidemiologists, immunologists and infectious disease experts. Their service was driven not by money or fame, but by a commitment to the collective health of Americans. ACIP meetings were transparent, being broadcast live and then archived on YouTube, while agendas were posted well in advance of each meeting. The public could request to ask questions at meetings as well as review slide decks that were presented. ACIP worked to avoid member conflicts of interest Kennedy's implication that he was reconstructing the committee to prevent conflicts of interest is far from the truth. In order to preserve objectivity and limit corporate influence on their recommendations, ACIP members already disclose any potential conflict of interest in advance. If a member has a potential conflict, they are not permitted to participate in vaccine discussions, or to vote on that vaccine or any vaccine that a company might bring before ACIP – even if that member didn't work on that specific vaccine. Opinion: As a doctor, I know it will take more than dietary changes to Make America Healthy Again Kennedy also implied that ACIP only ever adds vaccines to the schedule, acting as a rubber stamp for industry. But ACIP recommendations came after analyzing evidence and weighing the benefits and risks. The 1972 decision to stop vaccinating for smallpox was a significant and very well-informed move, reflecting an in-depth understanding of both the science and the broader public health context. The 2016 recommendation to reduce the number of doses for the HPV vaccine also shows that ACIP actively engaged in fine-tuning vaccination schedules based on the latest research, rather than to increase industry profits. It's crucial for these bodies to make decisions based on science, not external pressures or adherence to a certain ideology. Kennedy creates vaccine hesitancy that lead to childhood diseases As pediatricians, we have seen patients die from vaccine-preventable diseases. Our pediatric forefathers cared for children in iron lungs due to paralytic polio. Opinion: Please stop letting RFK Jr. make vaccine policies. His new COVID plan is deadly. Kennedy has planted the seeds of the anti-vaccination movement for more than two decades, despite evidence that contradicts his falsehoods. Due to the vaccine hesitancy and refusal he promotes, we are once again seeing more children succumb to vaccine-preventable diseases in America. So far in 2025, we have had pediatric deaths from measles and whooping cough, not to mention more than 200 deaths from influenza. Those numbers will only escalate in the future. Kennedy's decision to eliminate trustworthy members of the ACIP fundamentally changes the nature of this committee. Institutional memory and the trust of physicians were obliterated in one fell swoop. We hold little hope that HHS can put a new trusted committee together in time for the next scheduled ACIP meeting Jun 25-26, given Kennedy's preference for conspiracy theorists and other unqualified people. Through our careers as community pediatricians, we have been blessed by the opportunity to partner with wonderful families who desire what is best for their children. We fervently hope this relationship will be the most important factor when families make decisions regarding vaccinating their children. We call on our elected officials to reinstate the ACIP members Kennedy dismissed and to empower them to continue their work to limit damage from infectious diseases. Doing so will actually help make Americans healthier. James Keffer, MD; Chetan R Mukundan, MD; Jill Obremsky, MD; Elizabeth Triggs, MD; and David Wyckoff, MD, are local pediatricians practicing in different settings around Nashville. This column originally appeared in The Tennessean.

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