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This Surprising Exercise May Be Better for Your Brain Than Walking, New Study Suggests

This Surprising Exercise May Be Better for Your Brain Than Walking, New Study Suggests

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Reviewed by Dietitian Annie Nguyen, M.A., RDCycling was linked to a 19% lower dementia risk and 22% lower Alzheimer's risk.
Active travel may boost gray matter in memory-related brain regions, like the hippocampus.
Benefits of active travel persist regardless of genetics, especially for Alzheimer's risk.Dementia is a condition that disrupts memory, cognitive abilities and the ability to perform daily tasks, and its prevalence continues to rise globally, particularly among older adults. The good news? Staying physically active in middle age may be a powerful way to lower the risk of developing dementia. Research consistently highlights the protective benefits of regular movement, though many adults still fall short of meeting recommended activity levels.
One effective method to boost physical activity is what is referred to as 'active travel,' which includes walking or cycling for transportation. In other words, the simple act of skipping the car, bus or train and traveling by foot or bike may have a profound impact on brain health. Active travel not only promotes general health but has also been linked to a decreased risk of conditions like diabetes and potentially dementia.
But participating in active travel won't be a magic bullet to living a dementia-free life. The interplay between lifestyle habits and genetic predisposition of developing dementia adds another layer of complexity. While active travel presents health advantages for most individuals, the extent of those benefits may differ depending on a person's genetic risk for dementia.
To explore this relationship further, researchers in the UK conducted a study to determine how various modes of travel influence dementia risk, including Alzheimer's disease, alongside changes in brain structure, and their results were published in JAMA Network Open.
To conduct this study, researchers used data from the UK Biobank cohort. These participants came from different regions across England, Scotland and Wales. The study gathered extensive information about their demographics, lifestyles, health conditions and more through surveys and exams.
For this research, some participants were excluded, such as those already diagnosed with dementia at the start or shortly after (within 2 years), those who couldn't walk, and those missing travel-related data. The study looked at two groups of dementia cases: those who developed dementia before age 65 (younger onset dementia) and those diagnosed at 65 or older (later onset dementia). The researchers ultimately evaluated 479,723 participants with over 13 years of follow-up.
To gather information about travel habits, participants were asked to fill out a questionnaire that included questions about transportation choices that they used. Based on their answers, the researchers grouped travel modes into four categories: nonactive (using cars, motor vehicles, or public transport), walking, mixed-walking (a mix of walking and nonactive modes) and cycling and mixed-cycling (cycling combined with other modes).
To identify individuals with dementia, they relied on detailed health records using standardized codes for medical diagnoses.
They also used information from magnetic resonance imaging (MRI) scans of the brain, heart and abdomen. The research also looked at genetic factors related to dementia, focusing on the APOE gene, which is known to play a key role in dementia risk. Specifically, two genetic markers (called single-nucleotide polymorphisms) were used to determine whether a participant had a higher genetic risk. Participants were then grouped based on whether or not they carried the APOE ε4 gene variant.
Over a follow-up period of about 13 years, researchers found that out of all participants, 1.8% were diagnosed with dementia, including a very small group who developed it at a younger age (0.2%). The study compared different types of travel, like walking, cycling, or a mix of the two, with nonactive travel modes like driving. The results showed that people who cycled, or combined cycling with other modes, had a notably lower risk of developing dementia overall, particularly later-life dementia.
For instance, using a mix of walking reduced overall dementia risk by 6%, while cycling or combining cycling with other methods lowered the risk by 19%. Even for younger onset dementia specifically, cycling or mixed-cycling appeared to cut the risk by 40%. On the other hand, walking alone seemed to slightly increase the risk of Alzheimer's disease by 14%, but cycling or mixed-cycling helped reduce its risk by 22%.
When researchers studied brain scans , they found that cycling and combining cycling with other methods of travel were linked to slight increases in gray matter volume (GMV) in certain parts of the brain, including the hippocampus, which is important for memory. Walking and combining walking with other travel modes, however, were linked to slightly smaller volumes of gray and white matter in some areas. Importantly, these changes don't suggest a higher risk of dementia but highlight how different activities may affect the brain. Nonactive travel, like driving, didn't show any significant impact on brain structure in this study.
Interestingly, the researchers found that genetic risk didn't change the link between travel mode and early-onset dementia or Alzheimer's disease. However, for all dementia types and late-onset dementia, genetics did play a role. People who didn't have a specific genetic marker (APOE ε4) seemed to benefit more from cycling, showing lower dementia risks compared to those with the marker.
While these results are interesting and compelling, it is worth noting some limitations to this study. First, because younger onset dementia is relatively rare, the researchers couldn't break down the different types of cycling, making it hard to draw a firm conclusion. To improve this, future studies need more participants with younger onset dementia and longer follow-up periods. Second, they relied on people reporting their own travel habits, which might not always be accurate. Third, the researchers didn't track how travel habits changed over time, making it challenging to best understand these patterns. Finally, the study group lacked racial and ethnic diversity, as most participants were of European ancestry, so the results may not apply to all groups equally.
Understanding how active travel impacts dementia risk can ignite meaningful changes in your daily life, especially if you are focused on supporting your cognitive health. Imagine replacing those quick car rides with a refreshing walk or bike ride! Not only do you help the environment by cutting down on emissions when you do this, but you also take a proactive step toward protecting your brain health. Whether it's walking to the corner store, cycling to work or enjoying a peaceful stroll in the park, these simple shifts can deliver long-term benefits. The great thing is that incorporating more movement into your routine is achievable for most people and it may also support your brain health to boot.
Not all communities make it easy to bike or walk to work or while running errands. But if you can find time to go for a ride around the neighborhood or lengthen your parking lot walks at the grocery store, those little moments of extra activity could be helpful to your longterm health.
But active travel is just one piece of the bigger picture. Brain health thrives on a combination of regular exercise, a balanced diet, staying socially connected and getting quality sleep. While we can't control genetic factors, adopting healthy habits like active travel empowers us to take charge of what we can. The key is to tailor these efforts to your environment—whether that's walking more in pedestrian-friendly cities or cycling in bike-supportive areas. Small, consistent actions add up, and over time, they may help support not only your cognitive health but your overall health as well.
This study published in JAMA Network Open suggests that cycling may be linked to a 19% lower risk of developing dementia and a 22% lower risk of Alzheimer's disease. Researchers found that cycling may increase gray matter volume in the hippocampus, which plays a critical role in memory. Conversely, nonactive modes of travel like driving did not show meaningful effects on brain health. While genetic factors can influence these outcomes, the study suggests that physical activity through active travel offers protective benefits regardless of genetic predispositions, especially for those without high-risk genetic markers.
Whether through cycling, walking or other forms of active travel, making intentional choices about how we move through the world can yield profound health benefits. While active travel is not a one-size-fits-all solution, it can be a practical and rewarding way to support both brain and body. By combining movement with other healthy lifestyle choices, like eating a nutrient-rich diet, getting quality sleep and staying socially connected, you can take meaningful steps toward a healthier future.
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Structure Therapeutics Announces Two Late-Breaking Poster Presentations at the American Diabetes Association 85th Scientific Sessions Including New Preclinical Data for Oral Small Molecule Amylin Agonist, ACCG-2671
Structure Therapeutics Announces Two Late-Breaking Poster Presentations at the American Diabetes Association 85th Scientific Sessions Including New Preclinical Data for Oral Small Molecule Amylin Agonist, ACCG-2671

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Structure Therapeutics Announces Two Late-Breaking Poster Presentations at the American Diabetes Association 85th Scientific Sessions Including New Preclinical Data for Oral Small Molecule Amylin Agonist, ACCG-2671

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"It's The Trifecta Of Bad": Dentists Are Sharing The Things They Would Avoid Doing To Their Teeth At All Costs
"It's The Trifecta Of Bad": Dentists Are Sharing The Things They Would Avoid Doing To Their Teeth At All Costs

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"It's The Trifecta Of Bad": Dentists Are Sharing The Things They Would Avoid Doing To Their Teeth At All Costs

Brushing, flossing and visiting the dentist regularly — we all know the pillars of good dental hygiene. But knowing them and maintaining them are two different things. Nearly 50% of people above 30 have signs of gum disease and 26% of adults have untreated cavities, according to the Centers for Disease Control and Prevention. It's not uncommon to have issues with your teeth or gums, and dentists say certain lifestyle factors may be behind some of your oral health issues. In fact, common behaviors can negate the benefits of good oral hygiene — and you're probably guilty of some of them. Below, we spoke with dentists about the tooth-damaging habits and behaviors that they advise against and would never, ever do themselves: 1. They don't chew ice. 'The first thing that came to mind for me was chewing ice,' said Dr. Natalie Peterson, a clinical associate professor of dentistry at the University of Minnesota. 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Everything You Should Know About Hormonal Imbalance
Everything You Should Know About Hormonal Imbalance

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Everything You Should Know About Hormonal Imbalance

A hormonal imbalance can have a wide range of symptoms, from weight gain to fatigue. Treatment can help resolve many of the underlying causes. Hormones are your body's chemical messengers. Produced in the endocrine glands, these powerful chemicals travel around your bloodstream, telling tissues and organs what to do. They help control many of your body's major processes, including metabolism and reproduction. When you have a hormonal imbalance, you have too much or too little of a certain hormone. Even tiny changes can have profound effects throughout your body. Some hormone levels fluctuate throughout your lifetime and may result from natural aging. However, other changes occur when your endocrine glands produce too much or not enough of certain hormones. Read on to learn more about hormonal imbalances and how they might affect your health. Symptoms of hormonal imbalance Your hormones play an integral role in your overall health. Specific symptoms could indicate a hormonal imbalance. However, the symptoms you might experience depend on which hormones or glands are responsible. Common hormonal conditions that could cause imbalances may result in symptoms such as: Keep in mind that these symptoms are nonspecific. Having one or a few of them doesn't necessarily mean that you have a hormonal imbalance. Some of these symptoms may also reflect other chronic conditions. So, if you notice any notable changes in your body or energy levels, it's a good idea to talk with your doctor. Symptoms in people who were assigned female at birth (AFAB) In people with ovaries, the most common consequence of hormonal imbalance is polycystic ovary syndrome (PCOS). Your hormonal cycle also changes naturally during these stages: Symptoms of a hormonal imbalance specific to AFAB people include: heavy or irregular periods, including missed periods, stopped periods, or frequent periods hirsutism, or excessive hair on the face, chin, or other parts of the body acne on the face, chest, or upper back hair loss hyperpigmentation (darker patches on the skin), especially along neck creases, in the groin, and underneath the breasts skin tags vaginal dryness vaginal atrophy pain during sex night sweats headaches It's important to note that many of these issues, including hirsutism, can affect people of other sexes, too. Symptoms in people who were assigned male at birth (AMAB) Testosterone plays a vital role in development. If you aren't producing enough testosterone, it can cause a variety of symptoms. Symptoms of hormonal imbalance in AMAB people include: gynecomastia, or enlarged breast tissue breast tenderness erectile dysfunction (ED) decrease in beard growth and body hair growth loss of muscle mass loss of bone mass, otherwise known as osteoporosis difficulty concentrating hot flashes It's important to note that AFAB folks can also experience testosterone imbalances. Symptoms in children Children start producing sex hormones during puberty. Many children with delayed puberty will go on to experience typical puberty, but some have a condition called hypogonadism. Individuals with hypogonadism may experience: lack of development of muscle mass a voice that doesn't deepen body hair that grows sparsely impaired penis and testicular growth excessive growth of the arms and legs in relation to the trunk of the body gynecomastia menstruation that doesn't begin breast tissue that isn't developing the growth rate doesn't increase Causes of a hormonal imbalance A hormonal imbalance has many possible causes. They can differ depending on which hormones or glands are affected. Common causes of hormonal imbalance include: hormone therapy medications cancer treatments such as chemotherapy tumors, whether cancerous or benign pituitary tumors eating disorders chronic stress injury or trauma insulin resistance While hormonal imbalances may initially cause some of the conditions below, having these conditions can also lead to further hormonal imbalances: type 1 and type 2 diabetes diabetes insipidus hypothyroidism, or an underactive thyroid hyperthyroidism, or an overactive thyroid hyperfunctioning thyroid nodules thyroiditis hypogonadism Cushing syndrome, or high levels of cortisol congenital adrenal hyperplasia, which causes low levels of cortisol and aldosterone Addison's disease Causes unique to AFAB people Many causes of hormonal imbalance in AFAB people are related to reproductive hormones. Common causes include: menopause primary ovarian insufficiency, which is also known as premature menopause pregnancy breastfeeding PCOS hormone medications, such as birth control pills Tests for hormonal imbalance There's no single test available to help doctors diagnose a hormonal imbalance. Begin by making an appointment with your doctor for a physical exam. Be prepared to describe your symptoms and the timeline along which they've occurred. Include all medications, vitamins, and supplements you're currently taking. Your doctor may ask you questions such as: How often are you experiencing symptoms? Does anything help relieve your symptoms? Have you lost or gained weight recently? Are you more stressed than usual? When was your last period? Are you planning to get pregnant? Do you have trouble getting or maintaining an erection? Do you have vaginal dryness or pain during sex? Your doctor may suggest one or more diagnostic tests depending on your symptoms. You can also request that your doctor perform these tests. A healthcare professional can request a blood test to check your thyroid and estrogen, testosterone, and cortisol levels. Pelvic exam If you have a uterus, a doctor may perform an internal exam to feel for any unusual lumps, cysts, or tumors. If you have testicles, a doctor may check your testicles and scrotum for any lumps or abnormalities. Ultrasound An ultrasound machine uses sound waves to look inside your body. Doctors may request an ultrasound to get images of the: uterus ovaries testicles thyroid pituitary gland Additional tests Sometimes, more advanced tests are required. These can include: biopsy MRI X-ray thyroid scan sperm count test (semen analysis) At-home tests If you're experiencing symptoms of a hormonal imbalance, you may also consider using a home testing kit. These kits are available for a variety of conditions. However, while still best to talk with a doctor as they may recommend additional testing to determine the cause of a hormone imbalance, at-home tests can provide a starting point. Home testing kits for menopause measure follicle-stimulating hormone (FSH) in your urine. FSH levels increase when you enter menopause. Levels also rise and fall during a typical menstrual cycle. Other factors, such as the use of hormonal birth control, can also affect your FSH levels. Note that these kits can indicate that menopause may have started, but they can't tell you conclusively. A healthcare professional's confirmation may be necessary. Other home testing kits typically use saliva or blood from the fingertip to measure your cortisol levels, key thyroid hormones, and sex hormones such as progesterone and testosterone. Some tests may require a urine sample. These kits require you to send the sample off to a lab. Your test results are usually available online within 5 to 9 business days. The company LetsGetChecked provides at-home tests that have been approved by the Food and Drug Administration (FDA). However, many at-home tests have not received FDA approval. Regardless of which at-home test you choose, it is important to discuss your test results with your healthcare professional. Let them know if you're concerned about certain symptoms or a possible diagnosis. Treatment options for a hormonal imbalance Treatment for a hormonal imbalance will depend on what's causing it. Some common treatment options include: Estrogen therapy Be sure to discuss the risks and benefits of hormone replacement therapy (HRT) with your doctor. If you don't already have one, you can browse doctors in your area through the Healthline FindCare tool. Vaginal estrogen If you're experiencing vaginal dryness or pain during sex, a doctor may also recommend an estrogen cream, tablet, or ring. This local therapy helps eliminate many of the risks associated with systemic estrogen, or estrogen that travels throughout the bloodstream to the appropriate organ. Hormonal birth control Hormonal birth control can help regulate your menstrual cycles. Types of hormonal birth control include the: birth control pill birth control patch birth control shot vaginal ring intrauterine device (IUD) Some types of hormonal birth control may also help improve acne on the face and body. Anti-androgen medications Androgens are male sex hormones that are present in people of all genders. High androgen levels can be treated with medication that blocks the effects of androgens. These effects include: hair loss facial hair growth acne One androgen closely tied to hair growth and loss is testosterone. A 2020 study found that when not enough testosterone is produced, hair loss and lack of growth are common. Testosterone therapy Testosterone supplements can reduce the symptoms of low testosterone. In adolescents with delayed puberty, it stimulates the start of puberty. It's available in many forms, including injections, a patch, and gel. Testosterone replacement therapy (TRT) has risks, including to your cardiovascular system. Thyroid hormone therapy If you have hypothyroidism, the synthetic thyroid hormone levothyroxine (Levoxyl, Synthroid, Unithroid) can bring hormone levels back into balance. Metformin Metformin is a type 2 diabetes medication that may help some individuals with PCOS symptoms. The FDA has not approved it to treat PCOS, but it might help lower androgen levels and encourage ovulation. It is often prescribed off-label for this purpose. Flibanserin (Addyi) and bremelanotide (Vyleesi) Flibanserin (Addyi) and bremelanotide (Vyleesi) are the only medications that are FDA-approved for the treatment of low sexual desire in premenopausal people. Addyi is a pill, and Vyleesi is a self-administered injectable medication. These drugs may come with some serious side effects, such as severe nausea and changes in blood pressure. Talk with your doctor to see if either one could be right for you. Eflornithine (Vaniqa) This prescription cream is designed specifically for excessive facial hair. Applied topically to the skin, it helps slow new hair growth but does not eliminate existing hair. Natural remedies and supplements Many nutritional supplements on the market claim to treat menopause and hormonal imbalance. However, few of them are backed by scientific evidence. Many of these supplements contain plant-derived hormones, which are sometimes called 'bioidentical' hormones because they chemically resemble the body's natural hormones. However, there's no evidence to suggest that they work better than regular hormone therapy. They are also not regulated by the FDA to the same degree as prescription hormone medications. Some people find that yoga helps ease symptoms of hormonal imbalance. Yoga is excellent for your strength, flexibility, and balance. It may also aid in weight loss, which can further help regulate your hormones. You can also make the following lifestyle changes: Lose weight: If your doctor has recommended it, a reduction in body weight may help regulate menstrual cycles and increase the chances of getting pregnant. Weight loss may also help improve erectile function. Eat well: A balanced diet is an important part of overall health. Decrease vaginal discomfort: Use lubes or moisturizers free of parabens, glycerin, and petroleum. Avoid hot flash triggers when possible: Identify things that commonly trigger your hot flashes, such as warm temperatures, spicy foods, or hot beverages. Remove unwanted hair: If you have excess facial or body hair, you can use hair removal cream, laser hair removal, or electrolysis. Hormonal imbalance and acne The primary cause of acne is excess oil production, which leads to clogged pores. Acne is most common in areas with many oil glands, including the: face chest upper back shoulders Acne is often associated with the hormonal changes of puberty. But there's a lifelong relationship between acne and hormones. Acne and menstruation The menstrual cycle is one of the most common acne triggers. For many individuals, acne develops the week before they get their period and then clears up. Dermatologists recommend hormonal testing for people who have acne in combination with other symptoms, such as irregular periods and excess facial or body hair. Acne and androgens Androgens contribute to acne by overstimulating the oil glands. Children of all genders have high levels of androgens during puberty, which is why acne is so common at that time. Androgen levels typically settle down in a person's early 20s. Hormonal imbalance and weight gain Hormones play an integral role in metabolism and your body's ability to use energy. The only way to treat weight gain from a hormone disorder is to treat the underlying condition. Some hormone conditions, such as Cushing syndrome, can increase the risk of becoming overweight or developing obesity. Cushing syndrome causes high levels of cortisol in the blood. This leads to an increase in appetite and fat storage. Hypothyroidism, if the condition is severe, can also lead to weight gain. Slight hormone imbalances can happen during menopause. During this transition, many people gain weight because their metabolisms slow down. You may find that you still gain weight even though you're eating and exercising like usual. Hormonal imbalance and pregnancy During a typical pregnancy, your body experiences major hormonal changes, which are different from a hormonal imbalance. Pregnancy and PCOS Hormonal imbalances such as PCOS are among the leading causes of infertility. With PCOS, the hormonal imbalance interferes with ovulation. While you can't become pregnant if you're not ovulating, irregular ovulation in PCOS can still result in pregnancy. If you're trying to become pregnant and have PCOS, your doctor may recommend methods to improve your fertility. This may include losing weight, if a doctor recommends it. Prescription medications are also available that can stimulate ovulation and increase your chances of becoming pregnant. In vitro fertilization (IVF) is also an option if medication doesn't work. As a last resort, surgery can temporarily restore ovulation. PCOS can cause issues during pregnancy for both you and your baby. There are higher rates of: gestational diabetes miscarriage preeclampsia cesarean delivery (C-section) high birth weight admission to and time spent in the neonatal intensive care unit Becoming pregnant while living with PCOS does not mean an individual will experience any of the above problems. Talking with your doctor and following their advice is the best way to have a safe pregnancy and delivery. Pregnancy and hypothyroidism Babies born to parents with untreated hypothyroidism are more likely to have developmental issues. This includes intellectual and developmental disabilities. Managing your hypothyroidism along with your doctor's advice can help lessen these risks. Hormonal imbalance and hair loss Most hair loss, such as male pattern baldness, is hereditary but may be influenced by a hormone imbalance. Hormonal changes and imbalances can also sometimes cause temporary hair loss. In AFAB folks, this is often related to: pregnancy childbirth the onset of menopause An overproduction or underproduction of thyroid hormones can also cause hair loss. Other complications Hormone imbalances are associated with many chronic, or long term, health conditions. Without proper treatment, you could be at risk for several serious medical conditions, including: type 1 and type 2 diabetes diabetes insipidus high blood pressure high cholesterol heart disease neuropathy obesity sleep apnea kidney damage depression and anxiety endometrial cancer breast cancer osteoporosis loss of muscle mass urinary incontinence infertility sexual dysfunction goiter

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