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Baby Archie showed 'no signs of heart failure'

Baby Archie showed 'no signs of heart failure'

BBC News22-05-2025

A senior doctor has told an inquest said that a baby "had no clinical signs of heart failure" a month before he died at a Kent hospital. Archie Squire died of a rare heart condition just days after his first birthday in November 2023, following repeated visits to Queen Elizabeth the Queen Mother (QEQM) Hospital in Margate.Dr Emma Price, a consultant paediatrician with the East Kent Hospitals University NHS Foundation Trust (EKHUFT), told the inquest into his death that when she saw Archie in October 2023 "he didn't have any signs of heart disease" or "heart failure"."In all honesty it was a surprise" to find "Archie had a cardiac issue", she said.
Archie died in the early hours of 23 November 2023 following two cardiac arrests.His parents had made repeated visits to hospital over his short life, concerned about Archie's breathing as well as constipation and vomiting.A report by EKHUFT found that during Archie's treatment opportunities to diagnose him appropriately, which could have prevented his death, were "missed".The trust said it offered its "heartfelt condolences to Archie's family"."We will work with the coroner to give the family answers," it added.
'Period of reflection'
The inquest, held at North East Kent Coroner's Court in Maidstone, heard Archie had been admitted to the children's ward at the QEQM on 5 October 2023 suffering from breathing issues and constipation. Dr Price told the coroner, Sarah Clarke, that staff considered it a "working likelihood" that Archie's poor health "was related to his breathing".Under cross examination by the family's barrister, Emily Raynor, Dr Price said: "The thing that was really worrying me was his effort of breathing."Listening to his heart there was no indication of a murmur," she said. In later questioning Dr Price was asked if Archie's case had led to any changes in the way she practiced. "Of course it has changed the way I practice," Dr Price replied."We learn from every child. It makes us go through a significant period of reflection."
The inquest started on Monday and is set to last nine days.

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Are YOU eligible for free fat jabs on the NHS? As GPs start dishing out Mounjaro – all you need to know
Are YOU eligible for free fat jabs on the NHS? As GPs start dishing out Mounjaro – all you need to know

The Sun

time28 minutes ago

  • The Sun

Are YOU eligible for free fat jabs on the NHS? As GPs start dishing out Mounjaro – all you need to know

THEY are arguably the biggest medical breakthrough of recent times. And from Monday, so-called ' fat jab s' will be made available to many more Brits on the NHS. In what marks the dawn of a new era, GPs will begin prescribing the weight-loss jab Mounjaro in the first anti- obesity rollout of its kind. More than three million people are thought to be eligible for tirzepatide - the active drug in Mounjaro - the strongest jab on the market. Health chiefs hope it will turn the tide on England's obesity crisis which has seen rates double since the 1990s. Injections including Ozempic and Wegovy have previously only been available for type 2 diabetes or through specialist slimming clinics. Family doctors will now be encouraged to prescribe them in a bid to get more people on the meds. Experts hope widespread use will slash work sick days and boost the economy, while reducing rates of cancer, heart disease and dementia. But demand for the drugs is already huge and NHS clinics cannot dish them out fast enough. Here is everything you need to know as the rollout begins: What is Mounjaro and what has it been used for so far? 5 FOR anyone who has missed the frenzy, Mounjaro, aka tirzepatide, is the newest weight loss injection used on the NHS. It has been around since 2022 and triggers fullness hormones in the gut to prevent hunger and over-eating. This works the same as older jabs Wegovy and Ozempic, all known as GLP-1 agonists, but a recent trial showed it is more effective. A head-to-head study in the New England Journal of Medicine found Mounjaro caused 20 per cent weight loss over 18 months, while semaglutide – the active ingredient in Wegovy and Ozempic – led to 14 per cent. All the jabs were originally invented to treat type 2 diabetes but trials found they could also cause major weight loss. Pharma firms have cashed in on the discovery and UK prescriptions have skyrocketed. NHS prescriptions of Mounjaro in England surged from just 3,300 in 2023 to 1.1million last year, and more than a million people are estimated to be buying it online. Weight Loss Jabs - Pros vs Cons Who will be eligible in the new rollout? THE new rollout starting on Monday will allow GPs to prescribe tirzepatide for weight loss, starting with those patients whose weight places them at greatest health risk. Top of the list will be those with a body mass index (BMI) of 40 or higher and four weight-related health conditions. A BMI of 40 is roughly equal to weighing 16st (102kg) for an average height 5'3' woman, or 19st 6lbs (123kg) for an average 5'9' man. Weight-related conditions include high cholesterol, high blood pressure, prediabetes, type 2 diabetes, obstructive sleep apnoea and heart disease. Patients will likely be expected to have tried diet and exercise first before being offered a jab. Many are likely to miss out, as some 13.5million adults in England are obese but only 3.4million are estimated to be eligible in the rollout. How will the rollout be run and what is new? 5 WHAT'S new is that the rollout will be the first run by NHS primary care, led by GP surgeries. In theory this should make life easier for patients – but GPs will not be able to meet the huge demand. NHS bosses have admitted it will take a staggering 12 years to treat everyone who is eligible. Just 220,000 extra people are likely to get Mounjaro by 2028. Private prescriptions, costing about £100-£150 per month, already vastly outnumber that and are rising. Health Secretary Wes Streeting wants a faster rollout and more widespread use of the drugs but patients must also receive regular check-ups and lifestyle help. Officials are investigating whether they can dish them out through pharmacies or the NHS app to take a load off GPs. Professor Jason Halford, of the European Association for the Study of Obesity, said: 'These drugs have the potential to help millions. 'If the government and NHS are serious about prevention they need to reconsider their position on the speed of the rollout of these drugs.' Professor John Deanfield, a heart doctor at University College London, added: 'These drugs provide a real opportunity to delay many diseases of ageing all at the same time and potentially transform society. 'I hope it won't take 10 years to do something that is so needed.' What if my GP says no? MANY people are expected to miss out and some surgeries are already pouring cold water on patients' hopes. Fairhill Medical Practice in Kingston upon Thames said: 'Once we are able to prescribe weight loss injections they will be offered to those with the highest medical need only, which may mean that a lot of patients will be disappointed.' Millions who meet the prescription criteria will simply have to be denied the drugs because doctors are so busy. On top of everything else England's 6,300 doctors' surgeries have to deal with, they do not have the capacity to offer the necessary long-term supervision for millions more people at once. Experts reckon private prescriptions will rocket even more as frustrated patients give up waiting. If you are eligible but your GP denies you a prescription, you may be able to ask for a referral to specialist weight management services. Known as tier 2 and tier 3 weight management services, they may prescribe the jabs after other weight loss attempts. Many people are expected to find it easier to go private, with the injections widely available from high street pharmacies like Boots, Superdrug, and even Asda. Olivier Picard, of the National Pharmacy Association, said: 'NHS provision won't meet demand straight away, so we fully expect that many people will continue seeking it privately.' Advice for people buying them privately BUYING the drugs online might seem like the faster fix – but buyer beware. Slimming success stories are everywhere but so, too, are tales of horror. Many patients have been duped by dodgy sellers, suffered severe side effects or even died after taking jabs they bought online. Bargain prices, easy tick-box applications, or prescriptions with no follow-up, should all be red flags to online shoppers. Many pharmacies have been rapped for giving them away to people who do not meet the obesity criteria, potentially putting their health at risk. Dose strength is partly based on size and pretending you are fatter than you are could mean you end up with a medication too strong for your body, raising the risk of serious side effects. The most common side effects from the injections include feeling sick, vomiting, diarrhoea or other gut troubles. If not treated properly people can suffer more serious impacts like dehydration, gallstones, pancreatitis or allergic reactions – and more than 100 deaths in the UK have so far been linked to the jabs. The General Pharmaceutical Council issued new rules in February to say that all pharmacies must verify a patient's height and weight, and conduct at least a video call – if not face-to-face appointment – before prescribing weight loss injections. Dr Emily Pegg, associate vice president at Lilly, which makes Mounjaro, said: 'This is still a prescription-only medicine, should only be prescribed by a registered healthcare professional and needs to be dispensed by a registered pharmacy. 'It is not something that people should be able to buy by just going out and going on to a social media site and clicking a button and it gets delivered to them. 'That is not appropriate and is probably illegal. 'Patient safety is a high priority.' Everything you need to know about fat jabs Weight loss jabs are all the rage as studies and patient stories reveal they help people shed flab at almost unbelievable rates, as well as appearing to reduce the risk of serious diseases. Wegovy – a modified version of type 2 diabetes drug Ozempic – and Mounjaro are the leading weight loss injections used in the UK. Wegovy, real name semaglutide, has been used on the NHS for years while Mounjaro (tirzepatide) is a newer and more powerful addition to the market. Mounjaro accounts for most private prescriptions for weight loss and is set to join Wegovy as an NHS staple this year. How do they work? The jabs work by suppressing your appetite, making you eat less so your body burns fat for energy instead and you lose weight. They do this my mimicking a hormone called GLP-1, which signals to the brain when the stomach is full, so the drugs are officially called GLP-1 receptor agonists. They slow down digestion and increase insulin production, lowering blood sugar, which is why they were first developed to treat type 2 diabetes in which patients' sugar levels are too high. Can I get them? NHS prescriptions of weight loss drugs, mainly Wegovy and an older version called Saxenda (chemical name liraglutide), are controlled through specialist weight loss clinics. Typically a patient will have to have a body mass index (BMI) of 30 or higher, classifying them as medically obese, and also have a weight-related health condition such as high blood pressure. GPs generally do not prescribe the drugs for weight loss. Private prescribers offer the jabs, most commonly Mounjaro, to anyone who is obese (BMI of 30+) or overweight (BMI 25-30) with a weight-related health risk. Private pharmacies have been rapped for handing them out too easily and video calls or face-to-face appointments are now mandatory to check a patient is being truthful about their size and health. Are there any risks? Yes – side effects are common but most are relatively mild. Around half of people taking the drug experience gut issues, including sickness, bloating, acid reflux, constipation and diarrhoea. Dr Sarah Jarvis, GP and clinical consultant at said: 'One of the more uncommon side effects is severe acute pancreatitis, which is extremely painful and happens to one in 500 people.' Other uncommon side effects include altered taste, kidney problems, allergic reactions, gallbladder problems and hypoglycemia. Evidence has so far been inconclusive about whether the injections are damaging to patients' mental health. Figures obtained by The Sun show that, up to January 2025, 85 patient deaths in the UK were suspected to be linked to the medicines. Future of fat jabs WHILE the Mounjaro rollout is expected to kick off with a whimper and not a bang, it is hoped it will mark the beginning of a new era in weight loss medicine. Brits have been getting gradually fatter for decades and no medication or government policy has managed to beat the bulge. The drugs appear super-effective, reasonably priced and relatively safe, and could help millions slim down after failed diets. They are expected to reduce the risks of type 2 diabetes, cancer and dementia. And studies increasingly show they improve health in other ways on top of weight loss, too, reducing the risk of heart attacks and strokes. NHS medical director, Professor Sir Stephen Powis, believes they could one day be as transformative as cholesterol-lowering statins, which have slashed heart attacks since they were rolled out decades ago. Prof Powis said: 'I think over time it's highly likely that these drugs will become more widespread. 'I think there will be a combination of increased evidence of positive outcomes and costs dropping, and we will learn better how to deploy them. 'This is very exciting – we're in the foothills of learning how to use them.'

The 'game-changing' £21 item that sells every two minutes has shoppers floored with incredible results: 'This is brilliant - no more shaving'
The 'game-changing' £21 item that sells every two minutes has shoppers floored with incredible results: 'This is brilliant - no more shaving'

Daily Mail​

time36 minutes ago

  • Daily Mail​

The 'game-changing' £21 item that sells every two minutes has shoppers floored with incredible results: 'This is brilliant - no more shaving'

MailOnline readers can enjoy an extra 10 per cent off ANSWR's viral Exfoliating Hair Removal Drop, a bestselling alternative to shaving this summer. The Exfoliating Hair Removal Drop is proving to be a hugely popular method for getting rid of unwanted hair, with users saying they'll 'never go back' to shaving their legs. ANSWR Exfoliating Hair Removal Drop The ANSWR Exfoliating Hair Removal Drop is a game-changing hair removal tool, using a glass surface to gently slough away both hair and exfoliate the skin for soft, silky legs and arms. Best used on large areas of skin, the tool also targets dull skin and KP, also known as strawberry skin, for legs that are always holiday-ready. Now 20 per cent off in the brand's sitewide sale, readers can get an additional 10 per cent off with the code discount by using the code SUMMERSKIN10 at checkout. Act fast, as this special offer ends on June 26 2025. £20.81 (save £2.31) Shop Working with a circular rubbing motion on the skin, it promises to remove hair from the surface of the skin while also removing dead skin leaving the skin feeling baby-like. Perhaps best known for their viral At-Home Keratin Treatment, the ANSWR Exfoliating Hair Removal Drop is about to earn its keep in your beauty drawer this summer, too. Currently on sale for 20 per cent off thanks to the brand's storewide Summer sale, MailOnline readers can get an additional 10 per cent off with the code SUMMERSKIN10. The unique device has already converted scores of shoppers from razors and waxing, helping them say goodbye to painful nicks and 'strawberry' legs thanks to the use of friction to help remove hair from the surface of the skin while also removing dead skin. Highly rated by customers, the incredibly easy to use 'drop' has been designed with exfoliation in mind for smooth, soft and silky legs that you won't be able to stop touching. When used in circular motions, the glass surface gently sloughs away both hair and skin for soft, silky legs and arms. When used in circular motions, the glass surface gently sloughs away both hair and skin for soft, silky legs and arms. And while it is a gentler alternative to shaving or waxing it's also proved a winner with those with Keratosis Pilaris (KP), dryness, or strawberry skin, as with regular use it can improve the appearance and softness of the skin. For the best results, the ANSWR Hair Removal Drop should be used on dry skin. Simply buff the drop onto the desired area and you'll be able to watch in awe as hair and dead skin cells fall off in a matter of seconds. Currently on sale for £23.12, MailOnline readers can get an a further 10 per cent off with the code SUMMERSKIN10 taking the cost down to £20.81. Lasting up to six months, it's a cost-effective form of hair removal while also providing a sustainable alternative to traditional razors by replacing an average of 12 razors. 'This is brilliant- no more shaving - instant smooth and feels fabulous. Already recommended to several people. I love it and I'll never go back to shaving my legs again!'. Another agreed, adding: 'My legs are so smooth and no red raised marks anywhere! I braved shorts for the first time in years! Definitely highly recommend. Thank you again for a superb life changing product.' A third penned: 'A fantastic product that leaves legs hair-free and feeling like silk. So much better than shaving or waxing, it's so quick and easy and completely pain free. Love it!'. With one sold every two minutes, it's a great time to see what the hype is about for the hair removing device. Don't miss out on an extra 10 per cent off the ANSWR Exfoliating Hair Removal Drop with the code SUMMERSKIN10.

Can't sleep in the heat? Scientists reveal simple sock hack that's guaranteed to help you doze off
Can't sleep in the heat? Scientists reveal simple sock hack that's guaranteed to help you doze off

Daily Mail​

timean hour ago

  • Daily Mail​

Can't sleep in the heat? Scientists reveal simple sock hack that's guaranteed to help you doze off

With the UK in the grips of 2025's first heatwave, many of us will be struggling to doze off amid the tropical heat. If you can't sleep in the heat, scientists may have a counterintuitive solution. Although it might seem bizarre, putting on a pair of socks before you head to bed could be the key to drifting off peacefully. Studies have shown that this simple hack can help you fall asleep faster, stay asleep longer, and get a better night of rest. Wearing socks has even been proven to be effective at bedroom temperatures up to 23°C - hotter than nighttime temperatures in many places across the country this weekend. This strange trick works because our bodies' sleep and temperature regulation systems are deeply linked. Professor Eus van Someren, head of the Department of Sleep and Cognition at the Netherlands Institute for Neuroscience, told MailOnline: 'The brain not only regulates body temperature, but also reads out skin temperature. 'It may interpret warm feet as the right moment to fall asleep.' Why should you wear socks to bed? Our core body temperature has a day-night rhythm, starting to drop in the evening to reach its lowest point around four in the morning. That means the best time to sleep is when the core body temperature is on its way down. Normally, your body would cool itself close to bedtime by sending blood to the skin in a process called distal vasodilation, which makes the skin hot. Professor van Someren says this is like 'opening the radiator in the heating system in your home.' When you put on socks, this increases the temperature of your skin and creates signals that your brain mistakes for the warming caused by vasodilation. Your brain will then believe that it is time to fall asleep, and you will find it easier to drift off. But wearing socks also helps you get to sleep in a more counterintuitive way. When our skin becomes hot, the brain's temperature control system sends a signal to the body telling it to start venting heat by sending hot blood into veins near the surface. This causes an increase in vasodilation, sending blood rushing to the skin and dropping the core body temperature down to safe levels. Dr Michael Gradisar, head of sleep science and clinical psychologist and Sleep Cycle, says that wearing socks can trick the body into triggering vasodilation. This, in turn, causes the core body temperature to drop and helps you drift off to sleep. Dr Gradisar says: 'For people who need extra help warming their feet to assist their natural thermoregulation, socks can be helpful.' That might be especially useful if you suffer from Raynaud's phenomenon, poor circulation, or other conditions that interfere with blood flow to the extremities. A study published in 2018 by researchers from Seoul National University found that wearing bed socks significantly improved sleep even when the room was a toasty 23°C. Those who wore socks to bed fell asleep 7.5 minutes faster on average and woke up more than seven times less frequently during the night. How can you get the most out of this trick? To make this trick work for you, it's important that you maximise the amount your core body temperature falls before bed. Studies of skin heating techniques show that the best results were achieved when the feet were warmed about one hour before bedtime. That means you should put on socks before you get into bed to trigger the core cooling process early. Wearing the right material can also make a big difference, as you don't want anything that will trap too much heat or moisture. Dr Gradisar says that 'natural fibres like wool help' since these offer the best balance of breathability and warmth. Likewise, a study of sleepers conducted at 30°C and relative humidity of 50 per cent found that those wearing Merino wool sleepwear got a better night's rest than those wearing cotton. Additionally, if you can find a way of cooling down your body while your feet stay hot, that will ensure the best temperature gradient for sleep. Dr Gradisar recommends using a fan or other means to try and keep the bedroom as cool as possible. However, with temperatures over 30°C forecast this weekend, it is also important to avoid making your feet too hot during the night. Professor Bill Wisden, an expert on the neuroscience of sleep from Imperial College London, told MailOnline: 'Heat is like any intrusive stimulus such as pain, or noise or vibration. It wakes you up. 'Even if the socks help you go to sleep, having hot feet in summer will wake you up!' So, if you do find yourself getting too hot as you doze, simply kick the socks off before falling asleep. The increased vasodilation will linger for a while afterwards, and exposing your feet to the air could produce an even greater drop in core temperature, helping you fall asleep faster and stay asleep all night. What if you find socks uncomfortable? Many people may find the idea of wearing socks to bed an extremely unpleasant thought. Luckily, if you are one of those people who like to let their feet breathe, there is another way to get the same effects. Anything you can do to raise the temperature of your skin before getting ready for bed will trigger the same vasodilation effects as putting on a pair of socks. Professor Wisden says: 'I recommend just before bedtime, take a hot shower or warm bath, even on a warm evening. 'At the end of the day, this raises the probability that you will drift off to sleep.' You don't even need to have a full bath or shower if that seems like too much effort. Studies have shown that simply bathing the feet up to the ankle in 40°C water for about 20 minutes, one to two hours before bed, helps people fall asleep about 10 minutes faster on average. So, although it might sound odd, if you want to beat the heat this weekend, the best thing to do is to get as hot as possible before bed.

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