Latest news with #trials
ABC News
a day ago
- ABC News
Downing Centre to remain closed for four weeks due to flooding, some part-heard trials aborted
The busiest courthouse in New South Wales will be closed for at least one month, and some part-heard trials aborted, due to flood damage from earlier this week. The Downing Centre on Tuesday was shut down due to a burst water main on Castlereagh Street in Sydney's CBD. Electricity in the courthouse complex went out just before 10am, in the middle of court sittings, and the building was evacuated, with other neighbouring buildings also impacted. The court's media team said "extensive damage" was caused to the infrastructure of the building, the electricity, IT systems and other equipment. It is believed the building still has no power or water. "As a result, the Downing Centre will be closed for at least four weeks … it is clear that extensive repairs will be required which will take a lengthy period of time," a spokesperson said. Further updates from the Department of Communities and Justice are expected in the coming weeks as repairs commence to ensure the building is safe and fully operational prior to its reopening. "Judicial officers and court staff are making every effort to ensure matters are able to proceed wherever possible," the spokesperson said. The NSW Bar Association said it had received notice from the Chief Judge of the District Court, noting the likelihood of some trials being terminated due to the flooding situation. "The District Court's present focus is to complete trials that are part-heard, particularly those where the proceedings are of some age and where the accused is in custody," a statement read. The statement said arrangements were being made to source courtrooms elsewhere within the metropolitan area. Those with matters scheduled in the Downing Centre Local Court or District Court were advised to check the online court, relevant websites or get in touch with Downing Centre advisors. People with matters scheduled in the Drug Court were advised to contact the registry or their Community Corrections Officer. Jurors currently empanelled in criminal trials in the Downing Centre were told they will be contacted by the NSW Sheriff's Office with further updates. "I would ask that legal practitioners prepare parties and witnesses for the fact that over the next few weeks matters listed before the District Court in Sydney may not proceed as originally anticipated," a spokesperson for the Chief Judge of the District Court said. "I assure you that we are doing all we can to ameliorate the significant disruption the Court is facing."
Bloomberg
11-06-2025
- Business
- Bloomberg
Moderna Seeks Outside Investors to Fund Select Vaccine Trials
Moderna Inc. is in discussions with large drugmakers and financial firms to get funding for some late-stage vaccine trials as it works to develop its product portfolio while cutting costs. 'We are very actively talking to potential partners right now,' Chief Executive Officer Stephane Bancel said Wednesday at the Goldman Sachs Annual Global Healthcare Conference. The discussions are with pharmaceutical companies and other types of financial partners, he said.
Medscape
11-06-2025
- Health
- Medscape
Nonsurgical Options Show Modest Benefit in Chronic Back Pain
In people with nonspecific chronic low back pain, nonsurgical interventions like cognitive-behavioral therapy and mindfulness possibly showed small-to-moderate long-term benefits in reducing pain intensity and disability. However, the evidence was mostly of low-to-moderate certainty. METHODOLOGY: Researchers conducted a systematic review and meta-analysis of 75 randomized or cluster randomized controlled trials involving 15,395 participants aged 16 years or older (mean age, 45.7 years; median percentage of women, 61%) with chronic low back pain lasting at least 12 weeks. They assessed the effectiveness of nonsurgical interventions for chronic low back pain (including 91% trials on nonspecific chronic low back pain) with a focus on long-term (1-2 years) and very long-term (≥ 2 years) outcomes. Psychological, physical, and combination nonsurgical interventions, including cognitive-behavioral therapy, mindfulness, and multidisciplinary care, were assessed, with exercise being the most frequently assessed intervention. Interventions were compared with placebo or sham, adjuvant interventions, no intervention, or usual care. Pain intensity and disability were assessed using scales like the Numerical Pain Rating Scale and Oswestry Disability Index, respectively, along with other measures, and the certainty of evidence was assessed. TAKEAWAY: At long-term follow-up, small-to-moderate reductions in pain intensity and disability were possibly seen with cognitive-behavioral therapy (mean differences, -7.2 and -5.7, respectively) and mindfulness (mean differences, -10.0 and -9.3, respectively) in individuals with nonspecific chronic low back pain. The evidence was of moderate certainty. Goal setting and needling interventions probably resulted in small reductions in disability, with mean differences of -8.3 and -4.8, respectively. Multicomponent biopsychosocial care and behavioral therapy might have led to moderate and small reductions, respectively, in pain intensity in those with nonspecific chronic low back pain (mean differences, -10.2 and -7.4, respectively; low-certainty evidence). Multidisciplinary care could have led to small reductions in disability (mean difference, -8.3). At very long-term follow-up, multidisciplinary care may have led to a moderate reduction in pain intensity (mean difference, -10.1), whereas exercise may have resulted in a moderate decrease in disability (mean difference, -10.2) in those with nonspecific chronic low back pain. The evidence was mostly of low certainty. IN PRACTICE: 'Although we identified some interventions with long-term effects for people with chronic low back pain, the clinical importance of the effects is uncertain,' the study authors wrote. 'Greater attention is needed on developing and testing interventions with long-term effects for chronic low back pain.' SOURCE: The study was led by Hazel J. Jenkins, PhD, Macquarie University, Sydney, Australia. It was published online on May 28, 2025, in The Lancet Rheumatology . LIMITATIONS: The certainty of the evidence was reduced for most comparisons because of the quality of the studies and inconsistencies in the results. DISCLOSURES: The study reported receiving no specific funding. Some authors reported receiving grants, support for attending meetings, research fellowships, and serving as members of the executive board of the network and/or as members of associations outside the submitted work.
RNZ News
11-06-2025
- Automotive
- RNZ News
Auckland electric ferry hits water for first time
Auckland Transport's new electric ferry has hit the water for the first time. Workers began the slow process of bringing the vessel from the factory floor into the Tamaki River in Mt Wellington where it will undergo trials. It is hoped the New Zealand designed and made ferries will make ripples worldwide. Victor Waters reports. Tags: To embed this content on your own webpage, cut and paste the following: See terms of use.
CBC
10-06-2025
- Sport
- CBC
Bell Canadian Swimming Trials: Day 5
Watch the preliminaries from day five of the Bell Canadian Swimming Trials at Saanich Commonwealth Place in Victoria, B.C.
