
ICMR-NIV Pune inaugurates high performance computing facility
PUNE The Indian Council of Medical Research (ICMR) launched its first High Performance Computing (HPC) facility at the ICMR–National Institute of Virology (NIV) Pune on Saturday. The advanced system, named NAKSHATRA, was inaugurated by Dr Rajiv Bahl, secretary of the department of health research and director general of ICMR.
The facility has been developed under the Pradhan Mantri Ayushman Bharat Health Infrastructure Mission (PM-ABHIM) as part of a new project called 'High Performance Computing Next Generation Sequencing (NGS) Hub'. It is designed to boost the country's ability to process large volumes of genomic and bioinformatics data—an area that faced challenges during the Covid-19 pandemic due to limited computing resources.
Speaking at the inauguration, Dr Bahl praised the institute for its timely and strategic step towards 'Viksit Bharat 2047' vision by strengthening the country's genomic surveillance and data analysis capacity. He highlighted how enhanced computing resources are crucial in preparing for technology driven pandemic preparedness and future public health emergencies.
Dr Naveen Kumar, director, ICMR-NIV, emphasized the critical role the HPC cluster will play in supporting rapid, data-driven responses to outbreaks.
The newly commissioned HPC cluster features twelve compute nodes, offering a total of 700 cores and 1 petabyte of storage. The infrastructure is tailored to support complex bioinformatics workflows including next-generation sequencing (NGS), transcriptomics, phylogenetics, metagenomics, and structural bioinformatics. Initially, the facility will serve five ICMR institutes across the country, acting as a central repository for sequencing data and extending support to Viral Research and Diagnostic Laboratories (VRDLs) in the near future. This makes the Pune-based institute a critical hub for outbreak investigations and pandemic preparedness, with the potential to accelerate AI-driven drug and vaccine discovery.
Hashtags

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles


India Gazette
an hour ago
- India Gazette
Home grown less than 50 rupees' test aiding fight against Sickle Cell Disease
New Delhi [India], June 21 (ANI): Sickle Cell Disease, a genetic blood disorder, leads to severe health complications such as anaemia, frequent pain episodes and other debilitating symptoms, affecting millions worldwide, especially in India and Africa. According to Dr Prabhakar Kedar, Scientist F, ICMR- CRMCH, Chandrapur India has indigenous validated 35 company kits and 23 kits with 100 % accuracy and low cost for Sickle Cell Anaemia detection, 'we have validated so far 35 company kits and 23 have shown 100 per cent sensitivity and 12 kits 95 per cent sensitivity.' The sample collection is done from a finger prick mixed with buffer solution, and results are obtained in a few minutes. 'A drop of capillary blood (usually from a finger prick) is collected. 2. The blood is mixed with buffer solution and placed on the test strip or cassette, 3. Reaction: The test uses antibodies to detect different haemoglobin variants (HbA, HbS and control band).' He explained 'Colored lines appear on the strip within 10 minutes to indicate the presence of normal haemoglobin (HbA), sickle haemoglobin (HbS), and control band.' He said. On utilisation of these kits, he said 2 kits per month are used, and for each kit we use 50 Sickle homozygous blood samples, 50 heterozygous and 50 normal blood samples.' 'We used blood samples, which were first confirmed by the HPLC method, which is the gold standard for diagnosing sickle cell anaemia, ' he said. To support the fight against Sickle Cell Disease (SCD), two centres- ICMR-NIIH in Mumbai and CRMCH in Chandrapur, have been officially chosen by the government to test and approve new diagnostic kits. 'ICMR NIRRCH, along with PGI Chandigarh and ICMR-NIIH, conducted a comprehensive assessment and determined that point-of-care tests for Sickle Cell Disease/Trait among the high-risk population in India would be cost-effective if procured at INR 100 per test or below. Following the HTA recommendation, the National Health Mission instructed state health departments to procure the diagnostic kits at a maximum price of INR 100 per test. Through public tendering, the competitive procurement process drove the price of the kits down to INR 82 per test, significantly below the initial quote, resulting in a saving of Rs 1,857 crores. Subsequently, ICMR-NIIH has validated new kits, and further to it, the manufacturer has agreed to sell the kits at INR 50 per test,' states ICMR-CRMCH. These efforts are a big boost for the National Sickle Cell Elimination Mission, which aims to eliminate the disease from India by 2047. (ANI)


India Today
5 hours ago
- India Today
High on enamel spirits Maulana Azad Institute of Dental Sciences, New Delhi
The Maulana Azad Institute of Dental Sciences combines top-tier training, next-gen research and real-world outreach to shape some of the finest dental professionals in India (Photo: Chandradeep Kumar) No. 1: MAULANA AZAD INSTITUTE OF DENTAL SCIENCES 5 REASONS WHY IT IS THE BEST Whether it is public health dentistry, oral radiology, oral microbiology or preventive dentistry, the Maulana Azad Institute of Dental Sciences (MAIDS)—located in the heart of Central Delhi—has dedicated faculty across all major and emerging fields of dentistry. Declared a 'Centre of Excellence' by the Delhi government, MAIDS boasts best-in-class infrastructure. From dental chairs to digital units, every facility is state-of-the-art and fully operational. Its advanced tissue bank ranks among the best in India, producing graft materials to global standards. With just 50 BDS seats, the institute attracts top-ranking students through both national and state quotas. A strong culture of discipline, clinical precision and academic excellence defines the student community. MAIDS is also a hub for innovation. It is the only dental college in North India to host a DST- and ICMR-funded research and dental technology innovation hub, offering students hands-on access to cutting-edge projects with full institutional support. The institute's reach extends beyond its campus. Through six mobile dental vans under the National Health Mission, students provide care in rural and underserved areas, gaining invaluable real-world experience.
&w=3840&q=100)

Business Standard
7 hours ago
- Business Standard
ICMR-NIIH launches India's first national rare blood donor registry
In a first, the National Institute of Immunohaematology (NIIH) in Mumbai, operating under the Indian Council of Medical Research (ICMR), has launched a national registry for rare blood donors. This initiative aims to help patients with uncommon blood types — especially those with conditions like thalassemia and sickle cell disease — who often need repeated blood transfusions. Dr Manisha Madkaikar, Director of the ICMR-Centre for Research Management and Control of Haemoglobinopathies (CRHCM) in Nagpur, told PTI that the ICMR-NIIH is currently in discussions with the Director General of Health Services (DGHS) to link this rare donor registry with *e-Raktakosh*, the government's existing blood availability portal. This integration will make it easier for people with rare blood groups to locate matching donors and blood banks, while also helping blood banks manage their donor records and supplies more efficiently. High demand for blood in India According to the Central Drug Standard Control Organisation (CDSCO), India has over 4,000 licensed blood banks for its population of more than 142 crore. Dr Madkaikar pointed out that India has a significant need for blood transfusions due to a higher occurrence of blood disorders and pregnancy-related complications. 'Thalassemia itself contributes to 100,000 to 150,000 patients who require recurrent transfusions,' she said. She also highlighted the large-scale need for blood due to accidents and medical procedures. 'With more than 1,200 road accidents occurring every day in India, and with every year 60 million surgeries, 240 million major operations, 331 million cancer-related procedures, and 10 million pregnancy complications, a serious call for blood transfusion is recognised,' she added. Why minor blood group antigens matter? Most blood banks in India only match ABO and RhD antigens when issuing red blood cell components. But the International Society of Blood Transfusion (ISBT) has recognised over 360 antigens across 47 blood group systems. These lesser-known antigens are not routinely tested in India, Dr Madkaikar said. 'As a result, a mismatch of minor antigens between donor and patient blood group (BG) profiles can lead to red cell alloimmunisation (1–3 per cent in the general population, 8–18 per cent in thalassaemic patients). About 25 per cent of all immunised patients have been reported to receive unsatisfactory transfusion support due to presence of multiple antibodies or antibodies to high frequency antigens (HFA),' she explained. What counts as a rare blood group? Rare blood groups are typically those that lack high frequency antigens (seen in 1 in 1,000 people or less), are negative for common antigen combinations, or show a null phenotype. 'Meeting a demand for rare blood supply is challenging and time consuming for such patients. The need of a patient for rare blood can be the start of a series of events that may extend beyond the local blood centre and become a national or even an international search,' Dr Madkaikar said. To address this, a well-maintained database of rare and extensively typed blood donors is essential. Dr Madkaikar noted that 27 countries already have national rare donor registries. Until recently, India was not one of them. Earlier in 2019, ICMR-NIIH received approval for a Centre of Excellence project aimed at screening 4,000 regular 'O' group blood donors from four regions of India. This was done using advanced molecular techniques in partnership with major hospitals — KEM Hospital in Mumbai, PGIMER Chandigarh, MCH Kolkata, and JIPMER Puducherry. 'More than 600 donors negative for combination of antigens were identified along with 250 very rare blood group donors. The registry also includes 170 Bombay blood group donors, which is the commonly required rare blood type in India (approx 120–150 units/year). To access this inventory (ICMR-Rare Donor Registry of India (RDRI)), a web-based portal has been developed for systematic requisition and provision of blood to patients on time,' Dr Madkaikar said. She added, 'There is a plan to integrate this rare donor registry with e-Raktakosh of DGHS so that all the blood banks can contribute their rare donors and help in expansion of the registry. Last month we held a meeting with the DGHS.' India's first diabetes biobank In another landmark step last year, ICMR had established the country's first diabetes biobank in Chennai, in collaboration with the Madras Diabetes Research Foundation (MDRF). This facility collects, processes, and stores biological samples to support scientific research into diabetes and related disorders. The biobank aims to enhance understanding of the Indian forms of diabetes and contributes to ongoing studies, with appropriate permissions from ICMR.