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How a plague of 'mutating' super rats are taking over Sydney and becoming resistant to poison: 'Impossible to kill'

How a plague of 'mutating' super rats are taking over Sydney and becoming resistant to poison: 'Impossible to kill'

Daily Mail​11-06-2025

Black rats in Australia's biggest cities have developed a genetic mutation that increases their resistance to one of the most widely used poisons.
New research led by Edith Cowan University PhD student and environmental toxicologist Alicia Gorbould found the mutation in over half the rats tested in Brisbane, Melbourne, Perth and Sydney between 2021 and 2024.
The mutation suggests the rats have developed a resistance to second-generation anticoagulant rodenticides, also known as SGARs, but other animals continue to be inadvertently killed by these types of rat poison.
SGARs are deadly to secondary predators, such as tawny frogmouths, Australian boobooks and eastern barn owls, that feed on rodents.
Black rats are the most common introduced rat in Australia and experts warn their increase in resistance to poison could pose a serious risk to the country's wildlife.
Ms Gorbould also expressed fears of a public health crisis as Australians may be using larger quantities of poison in an attempt to rid rats from their home.
However, instead of working effectively, this would serve to introduce more poison into the food chain, and into waterways.
Animals that consume the poison, which prevents blood clotting, die from internal bleeding.
Research carried out by Ms Gorbould and her team found genetic mutation Tyr25Phe, which is associated with resistance to anticoagulant rodenticides, in 53.7 per cent of the rats they tested.
The tests were carried out on the tails of 191 rails caught in Australia's fourth most populated cities.
Alarmingly, the gene was found in over 80 per cent of black rats tested in Perth, over 45 per cent in Sydney, 39 per cent in Melbourne.
Tyr25Phe was found in none of the 10 rats tested in Brisbane.
'If you're using one of the baits that don't work … people will probably try to use more, and more, and more,' she told Daily Mail Australia.
'And so it's feeding back into that cycle of increasing the rates of resistance in the population, increasing those non-targeted poisonings, and then we're ending up essentially with a public health issue because we've got these rats that can't be controlled.'
Second-generation rodenticides are so potent they are banned in the United States, Canada and the European Union.
The poison makes it way up the food chain and kills other animals in a huge risk to Australia's biodiversity.
Scientists at Deakin University previously found rat poison was to blame for killing powerful owls.
In 2022, in a study looking at the prey of powerful owls, the team dissected 160 possums.
They found rat poison in 91 per cent of brushtail possums and 40 per cent of ringtail possums tested.
Ms Gorbould urged Australians to consider against using rat poisons and instead look to non-poison alternatives.
She suggested snap traps and electrocution traps while pointing out that 'prevention is better than cure'.
The scientist advised the best thing people can do is make sure they don't have places for rodents to live by removing waste from their yards.

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