
Regulators Approve a Twice-Yearly Shot to Prevent H.I.V. Infection
The Food and Drug Administration on Wednesday approved a twice-yearly injection that provided a near-perfect shield against H.I.V. infection in clinical trials.
The approval is among the most anticipated developments in the prevention of H.I.V. But it arrives during deep cuts to global health programs that were expected to purchase and distribute the drug in low-income countries.
To what extent the drug, called lenacapavir, can now be rolled out is uncertain.
'We're on the precipice of now being able to deliver the greatest prevention option we've had in 44 years of this epidemic,' said Mitchell Warren, executive director of the international H.I.V. prevention organization AVAC.
'And it's as if that opportunity is being snatched out of our hands by the policies of the last five months,' he said.
With much less money available, governments abroad may instead choose to prioritize treatment of the infected.
'We were so excited about the possibilities,' said Dr. Linda-Gail Bekker, who led a clinical trial of the drug. 'I don't think any of us envisaged this year going quite the way it has.'
Want all of The Times? Subscribe.
Hashtags

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Yahoo
an hour ago
- Yahoo
Ben Askren: New Update Reveals Emotional Details on UFC Veteran's Ongoing Health Battle
Ben Askren: New Update Reveals Emotional Details on UFC Veteran's Ongoing Health Battle originally appeared on Athlon Sports. Health battles in combat sports don't always end when the final bell rings. For some fighters, the toughest rounds come long after the crowds have quieted and the lights have dimmed. These are the moments that reveal what heart truly looks like. In a sport defined by grit and resilience, fans recently received a heartfelt reminder that the most meaningful fights often take place far from the spotlight. And now, one veteran's family has offered a sobering update on an ongoing battle that continues behind the scenes. Advertisement On June 7, both the MMA and wrestling worlds were shaken by reports that Ben Askren, known for his wrestling dominance and outspoken personality, was in critical condition due to severe pneumonia. Ben AskrenGetty News of his situation spread rapidly, with fans and former fighters flooding social media in a show of unified support. Today, a deeply personal update was shared via his wife Amy's Instagram story, revealing the latest developments in his recovery. 'Ben has been in limbo for a while… Ben is still on a ventilator and ECMO to support him while he heals. There are good days and bad, and on the good days, they've been able to wean his sedation enough for him to open his eyes and squeeze hands… I'm still praying for a miracle with his current lungs, but they are currently starting the evaluation process for lung transplant… Please pray for his continued healing, and if transplant is the solution, that he can get on the list quickly and easily… Give your loved ones a hug today and make sure you're prepared for situations like this. Ben is the healthiest guy I know and I never could have expected this.' The veteran remains in critical condition, with signs of response but no full awakening. As transplant evaluations begin, the outpouring of support has not wavered. The wrestling and UFC communities continue to rally behind him—holding onto hope, offering strength, and standing united for one of their own. Advertisement Related: Team Makhachev Reveals UFC's Power Play to Elevate Ilia Topuria Related: UFC Champion Shares Hard Truth About Jon Jones: 'It's a Responsibility' This story was originally reported by Athlon Sports on Jun 17, 2025, where it first appeared.
Yahoo
an hour ago
- Yahoo
DHS Secretary Kristi Noem Released from Hospital After Allergic Reaction
DHS Secretary Kristi Noem Released from Hospital After Allergic Reaction originally appeared on L.A. Mag. Secretary of the U.S. Department of Homeland Security Kristi Noem was hospitalized Tuesday in Washington D.C. following an allergic reaction, and released later that to Department of Homeland Security spokeswoman Tricia McLaughlin Noem is 'alert and recovering' after receiving treatment for the reaction. Noem was transported to the hospital by ambulance from Joint Base Anacostia-Bolling in Washington according to a DHS official. Noem, who assumed leadership of the DHS in January, oversees a workforce of roughly 260,000 employees tasked with responsibilities ranging from immigration enforcement and airport security to disaster response. Since taking office, she has maintained a high profile presence in her role amid backlash against recent immigration enforcement actions, and has frequently taken part in immigration enforcement last week, Noem held a press conference that drew national attention when U.S. Senator Alex Padilla was forcibly removed and flanked by federal agents. This story was originally reported by L.A. Mag on Jun 19, 2025, where it first appeared.


Health Line
an hour ago
- Health Line
The Progression of Hepatitis C: What Are the Stages?
Key takeaways Every case of hepatitis C begins as an acute infection. Infections that last more than 6 months are considered chronic. Many people with hepatitis C end up with chronic hepatitis C that can last a lifetime. The consequences of long-term infection include liver damage, liver cancer, and even death. Early detection and treatment are key for stopping the progression of hepatitis C and avoiding major complications. Hepatitis C is an infection caused by the hepatitis C virus (HCV) that leads to liver inflammation. Symptoms can be mild for many years, even while liver damage is taking place. Many people with hepatitis C end up with chronic hepatitis C that can last a lifetime. The consequences of long-term infection include liver damage, liver cancer, and even death. Early detection and treatment are key for stopping the progression of hepatitis C and avoiding major complications. How HCV is transmitted HCV is a bloodborne pathogen. That means the virus is transmitted through contact with blood that contains HCV. To reduce your risk of exposure: Avoid sharing razors, nail clippers, toothbrushes, and other personal hygiene items. Avoid sharing needles, syringes, and other sharps. Disinfect wounds and surfaces touched by blood and other bodily fluids as soon as possible. Patronize tattoo and body piercing studios that practice proper sterilization practices. HCV usually isn't transmitted through sexual contact, but it's possible. Using condoms, gloves, and other barrier methods during sexual activity can help reduce your risk. Birthing parents with HCV can also transmit the virus during childbirth, but not through nursing. Early warning signs In most cases, there are no early warning signs. Most people are symptom-free and remain unaware of the infection. Others experience mild symptoms, such as fatigue and loss of appetite, which tend to resolve independently. According to the World Health Organization (WHO), around 30% of people clear the infection within 6 months of exposure without medical intervention. Acute hepatitis C The acute phase of hepatitis C is the first 6 months after contracting HCV. Early symptoms may include: fever fatigue loss of appetite nausea and vomiting In most cases, symptoms clear up within a few weeks. If your immune system doesn't fight the infection on its own, it enters the chronic phase. Given the vague nature of the symptoms, hepatitis C may go unnoticed for years. It's often discovered during a blood test that's being done for other reasons. Chronic hepatitis C Approximately 70% of people will go on to develop chronic hepatitis C. However, even in the chronic phase, it may take years for symptoms to show. The progression begins with inflammation of the liver, followed by the death of liver cells. This causes scarring and hardening of liver tissue. Roughly 15–30% of people with chronic hepatitis C go on to develop cirrhosis of the liver within 20 years. Cirrhosis of the liver When permanent scar tissue replaces healthy liver cells, and your liver loses the ability to function, it's called cirrhosis. In this condition, your liver can no longer heal itself. This can cause fluid to build up in your abdomen and the veins in your esophagus to bleed. When the liver fails to filter toxins, they can build up in your bloodstream and impair brain function. Cirrhosis of the liver can sometimes develop into liver cancer. This risk is greater in people who drink excess alcohol. Treatment of cirrhosis depends on the progression of the condition. End-stage hepatitis C Chronic hepatitis C can cause serious long-term health consequences when it leads to liver scarring. End-stage hepatitis C occurs when the liver is severely damaged and can no longer function properly. Symptoms may include: fatigue nausea and vomiting loss of appetite abdominal swelling yellowing of the skin and eyes (jaundice) muddled thinking People with cirrhosis may also experience bleeding in the esophagus, as well as brain and nervous system damage. A liver transplant is the only treatment for end-stage liver disease. Factors that affect the progression Because alcohol is processed in the liver, consumption of excess alcohol can hasten liver damage, so it's important not to drink it. Damage also progresses faster in people with weakened immune systems, such as those with HIV. People who also have hepatitis B are at an increased risk of developing liver cancer. Males who have cirrhosis tend to experience faster disease progression than females. People over 40 with cirrhosis also experience faster disease progression than younger people. If you suspect that you have hepatitis C, consult with a healthcare professional as soon as possible. Early detection and treatment are the best ways to prevent and treat any serious complications or progression. Frequently asked questions What is the life expectancy of a person with hepatitis C? Many people live for years after receiving a hepatitis C diagnosis. Your outlook ultimately depends on the stage at diagnosis, whether liver damage has occurred, and your overall health. How many people experience long-term complications of hepatitis C? According to the Centers for Disease Control and Prevention, approximately 5–25 out of every 100 people who have hepatitis C develop cirrhosis within 10–20 years. People who develop cirrhosis have a 3–6% annual risk of hepatic decompensation or 'decompensated' cirrhosis. This occurs when your liver function decreases and may be a sign of end-stage hepatitis C. People who develop cirrhosis also have a 1–4% annual risk of developing hepatocellular carcinoma, which is the most common type of primary liver cancer. What are the chances of dying from hepatitis C? Hepatitis C alone typically isn't fatal, but complications from untreated or advanced hepatitis C can be. People who develop decompensated cirrhosis, for example, have a 15–20% risk of death within a year of diagnosis. If you have questions about your outlook, talk with your healthcare professional. They're the only person with direct insight into your diagnosis and medical history.