Conference MDAngle: ASCO 2025 Endometrial and Related Cancer
Preconference Considerations
ASCO 2025: A Preview of Advancements in Endometrial Cancer
Dr Matulonis previews key updates in gynecologic cancers, with a focus on endometrial cancer. She notes promising data from a phase 2 trial of benmelstobart plus chemotherapy, as well as results from the DUO-E and FRUSICA-1 studies. Dr Matulonis also looks forward to phase 3 results in ovarian and cervical cancers, including the KEYNOTE-A18 and ROSELLA studies. Quick Clinical Takeaways
Coming soon: Dr Matulonis highlights new data and progress regarding endometrial and related cancers immediately following ASCO. How Will My Patients Benefit?
Coming soon: Reflections from Dr Matulonis on how new data from ASCO will affect her patients with endometrial and related cancers. Lead image: Medscape
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CBS News
26 minutes ago
- CBS News
Pandemic-era puppies, kittens now filling San Francisco shelters beyond capacity
The COVID-19 pandemic is still having a deadly effect on the pet population. The number of unwanted animals is straining San Francisco's shelter capacity to the breaking point, sometimes with tragic results. Just about every animal shelter in the state is jammed these days and it all points back to the pandemic when shelters were empty and it was hard to find any animal to adopt, as people tried to cope with COVID isolation. But also at that time, spaying and neutering were suspended or drastically reduced. And now those generations of puppies and kittens are filling the shelters. "So, not just in San Francisco, but in California and nationwide, we are like two million spay/neuters behind. So, that just leads to more and more accidental breeding," said Virginia Donohue, Executive Director of San Francisco's Animal Care and Control. "Pre-pandemic, we were full a couple times a year. Now we're full a couple times a month. It is a constant problem. It's no longer an occasional problem." And it can have heartbreaking consequences. SF Animal Care and Control works to find unwanted pets a home, but when none is available, they must turn to euthanasia to make room. "We try very hard to euthanize just for medical and behavior issues," said Donohue. "But there are points when an animal is here too long and nobody is coming for it, we don't have a place for it to go and its behavior is deteriorating. Then we're going to euthanasia." One of the reasons the city's public animal shelter is so full is because its major adoption partner, the San Francisco SPCA, is taking a lot fewer dogs and cats than it used to. The SF SPCA, which is a private entity, has joined forces with the Stockton SPCA and is now rescuing a lot more unwanted pets from the Central Valley. "Historically, they've taken as many as 600 dogs," said SF's Donohue. "Currently, it's under 200. So, obviously, that's a pain point." It's also a reason why Animal Care and Control is having to turn to euthanasia. Another is that the shelter has a "custody" program that holds dogs up to two weeks for people who go to jail or the hospital or who die. That all takes space from those pets looking to be adopted. On Saturday, a dog owner named Ethan said he sometimes wonders where they're all coming from. "To see the amount of people out there that have dogs that aren't taking care of them, like, I don't really understand how they got these dogs in the first place," he said. The dogs are out there, many in desperate need of a caring home. But there is only so much space in the shelters and reducing the population is now more than just a humane thing to do. It's becoming a matter of life and death. "I mean, don't get a dog if you weren't intending to get a dog," Donohue said. "But if you want a dog, just look at your local shelter first. Even if you don't find the dog of your dreams there, just look and see what's available."
Yahoo
an hour ago
- Yahoo
How to cook with canned chicken, according to a dietitian who was 'very pleasantly surprised' when she gave the budget-friendly meat a chance
Canned chicken wasn't something Nicole Addison grew up eating, but the registered dietitian and recipe developer knows a workhorse ingredient when she sees it: "I don't really know why, but it was just never in our staples. And then I kind of just started seeing more people talking about it online, and then I was like, 'You know what? I should try it for research purposes and then also to see if it works in some of my recipes,'" she tells Yahoo Canada by phone from Toronto. "When I am testing recipes, I want to make sure that different options work. And then I was like, 'Wow, this is actually good.' I feel like it can sometimes have a bad connotation with it, like people are like, 'Ew, canned chicken. That's not something I want to try.' But then when you actually give it a chance, I was very pleasantly surprised." I feel like I eat canned tuna all the time. So really, what's the difference between canned tuna and canned chicken?Nicole Addison So, it makes sense that when Addison recently spotted a $22 package of chicken breasts at a grocery store, it made her think of even more ways that canned chicken could help folks eat well while staying budget-friendly: "I think everybody's looking for quick and easy protein options right now, just because I feel like no one really has any time. The thing that draws me to it is convenience. You don't have to cook it, and it's great in recipes where you're adding other ingredients to it." Here, we share Addison's top tips for incorporating this affordable protein into your diet. Plus, discover below a five-ingredient chicken salad recipe that's easy for anyone to recreate. View this post on Instagram A post shared by Nicole Addison, RD, MHSc (@nourishedbynic) Addison mentions affordability is a key reason behind considering canned chicken, alongside convenience since canned chicken is precooked. But that's not the only reason it feels like a kitchen shortcut: "There's really not a lot of mess, and you don't have to clean anything, which is awesome," Addison adds. "I feel like a good summer too, you don't want to turn on the oven, you don't want to have to do the dishes," making a shortcut ingredient like this one an easy win. The Canadian dietitian, who aims to empower people to eat healthier, says the minimal cleanup and prep can remove significant barriers for folks who are time-starved. It can also benefit anyone simply looking to get a meal on the table quickly, and with the right canned chicken recipe, taste won't be sacrificed. Sodium is one ingredient that should be top-of-mind if you're shopping for canned chicken. While fresh chicken breast typically has nothing added to it, canned versions may include ingredients that help preserve its shelf-stable quality. "That is one thing I always want people to be mindful [of], especially as a dietitian. People typically are eating more sodium than they need to, so just being mindful of that and looking for lower-sodium options is always a great option," Addison explains. For example, a can of Maple Leaf flakes of chicken includes 350 mg of sodium per serving. For Costco's Kirkland brand of canned chicken breast, there's 190 mg of sodium per quarter cup. A President's Choice Blue Menu can of seasoned chicken breast may be low in fat, but each serving has 200 mg of sodium. Addison adds that when following a recipe and subbing canned chicken for other forms of protein, it's likely safe to not add as much salt as you usually might: "There's already going to be some of that salt in the chicken already," she shares. "Otherwise, the only difference [compared to regular chicken is] canned chicken is cooked already, so you don't need to do any of that prep time, or it's cooking time," she adds, saying the nutritional values of both products are nearly identical (again, save that potential bump in sodium in canned chicken). Try using canned chicken in cold recipes, like sandwiches or salad Chicken salad recipes are some of Addison's most popular recipes Cooking with canned chicken can be as easy as adding it to a bowl and mixing other ingredients in "I wouldn't recommend using it in recipes calling for a whole chicken breast as one piece, just because it usually won't equate," Addison suggests when asked how canned chicken can be used. "It's very versatile, so it can be used in pretty much every recipe that is cold, I would say. It's great in sandwiches, it's great in wraps, it's great in chicken salad, it's great on top of a salad." Addison adds one of the most popular recipes on her website is a shredded chicken salad recipe that she's used canned chicken in to great success. While the recipe was originally developed with chicken breasts, canned chicken would be a quicker, more wallet-friendly spin on the simple meal. "I would always say, my most popular recipes are definitely my chicken salad recipes. I feel like people are always looking for a very quick lunch option, and those would be the perfect recipes to try canned chicken in, just because I call for shredded chicken in the recipe," she says. "You can easily cook a chicken breast if you want to. But canned chicken is a great option because all you have to do is open the can, add it directly into the bowl and then add in whatever other ingredients." View this post on Instagram A post shared by Nicole Addison, RD, MHSc (@nourishedbynic) Use a can of low-sodium chicken Add your barbecue sauce of choice Include Greek yogurt or mayonnaise Throw in some bagged coleslaw mix Sprinkle some salt and pepper In a large mixing bowl, combine the canned chicken and coleslaw with a few tablespoons of barbecue sauce and Greek yogurt, adding more sauce if needed for your desired consistency. It should be creamy and saucy like a typical chicken salad. Addison says the above mixture is perfect as a sandwich filling, a dip for crackers or stuffed in a wrap. "You kind of just mix it all together and it makes such an easy, versatile protein option," she says. View this post on Instagram A post shared by Nicole Addison, RD, MHSc (@nourishedbynic) As Addison prepares to test more ways to make meals starring canned chicken, she reflects on what keeps her excited about finding new uses for affordable ingredients. "I am a registered dietitian, so I feel like that's kind of where most of my inspiration has come, just being able to see so many different people struggling with healthy eating in general. I feel like social media is a great place, but it can also be a very overwhelming place — especially for people looking for reliable information relating to healthy eating," she shares. "I feel like everybody kind of has a take on what they think is best and what works for them. And not everybody has credentials." She says her mom — a person who doesn't love cooking but wants her family to eat well — is a constant inspiration when it comes to her creating simple, straightforward meals. "Because I don't think healthy eating should be something that needs to be as complicated as it's become."
Yahoo
an hour ago
- Yahoo
WNP Launches All-in-One Hyaluronic Acid Skincare Set, Pioneering a "3-Step Scientific Skincare Method"
Culver City, California--(Newsfile Corp. - June 22, 2025) - Skincare brand WNP officially launched the "All-in-One Hyaluronic Acid Skincare Set" on its website, introducing its original "Three-Step Scientific Skincare Method." The set integrates five key skincare steps - cleansing, hydration, repair, brightening, and early-stage anti-aging - into a comprehensive skincare system based on four core innovations: nano-delivery, HTAC thermal water dynamics, 4D hyaluronic acid, and microencapsulation technology. This set offers a streamlined solution for everyday skincare needs. From cleanse to anti-aging - the complete, science-backed routine for hydrated, balanced, glowing skin. To view an enhanced version of this graphic, please visit: Four Key Innovations Nano-Liposome Delivery WNP utilizes nano-liposome technology to reduce Ceramide NP particle size to below 100 nm, enabling targeted delivery to the basal layer of the stratum corneum. Lab tests show it helps fill intercellular lipid gaps and reduce transepidermal water loss, offering industry-leading repair benefits for sensitive and barrier-damaged skin. HTAC Thermal Decomposition Water Dynamics WNP's toner features Italian patented HTAC technology, which protects red algae and recombinant collagen activity. Tests show it boosts natural hyaluronic acid production by 124% and cellular mitochondrial activity by 229%. 4D Hyaluronic Acid Multi-Layer Hydration Based on Bloomage Biotech's 4D hyaluronic acid formulation, four molecular weights of hyaluronic acid penetrate from the epidermis to the dermis. Combined with a water-in-oil lamellar emulsion structure, this provides deep, lasting hydration. Microencapsulated Time-Release Salicylic Acid Salicylic acid is microencapsulated for sustained release of active ingredients, delivering gentle exfoliation while minimizing irritation. Ideal for daily use on sensitive or combination-oily skin. Five Steps, One Streamlined Routine Gentle Cleansing: A non-soap amino acid cleanser with pH 5.5-6, refined through 45℃ natural crystallization to remove excess emulsifiers. Fine foam gently purifies without residue. Soothing & Hydration: A serum-texture toner that forms a water film on contact. Functions as both mist and toner for instant moisture. Targeted Hydration: 3% Hyaluronic Acid Capsules, a TikTok bestseller, delivers precise hydration without pilling. Brighten & Even: A matrix of niacinamide, SymWhite®377, and vitamin C derivatives to block melanin transfer and fade oxidized spots. Early Anti-Aging: Patented recombinant collagen, triple peptides, and multiple ceramides to rebuild elasticity and visibly firm skin within 28 days. Brand Vision "With this launch, WNP merges cutting-edge nano-delivery with a multi-dimensional hyaluronic hydration system to redefine what 'minimalist skincare' can mean," said WNP's Chief Product Spokesperson-Dr. Emily. "We believe skincare is shifting from ingredient stacking to true tech-enabled performance-and this launch is the clearest expression of that evolution." About WNP WNP (Wake Nature Perfection) is a science-driven skincare brand based in Asia, rooted in the philosophy of precision skincare. It integrates top-tier dermatological research with global innovations in active ingredients. As an industry innovator, WNP has introduced multiple "first-of-its-kind" technologies in both domestic and international markets, committed to delivering safe, effective, and targeted skincare solutions. For more information, please visit Source: WNPContact: MattDepartment: Brand TeamEmail: matt@ To view the source version of this press release, please visit
