
Opinion In a black-and-white world, colour me olo
In 1856, an 18-year-old was trying to find the cure for malaria. Instead, he found a way to create the colour purple. William Henry Perkin, a student at London's Royal College of Chemistry, dipped a piece of cloth into his mixture of coal aniline and chromic acid. The cure for malaria was still about a century away, but what Perkin did discover was a way to create the first colour in synthetic form. Researchers from UC Berkeley and the University of Washington this week made a similar discovery. They had laser pulses fired into their eyes and claimed to have found 'olo', an 'incredibly saturated' blue-green, a colour 'never seen before by the human eye'.
The discovery was made using a device called the Oz Vision System, named after Emerald City in L Frank Baum's The Wonderful Wizard of Oz. The colour cannot be seen by the naked eye without laser stimulation. The scientists used the Oz to stimulate only the M (medium) cone cells in the eye, allowing them to view the colour. It was named 'olo' to denote the binary 010, indicating that of the three cone cells in the eye — L (long), M and S (short) — only one, the M, is stimulated.
Scientists have argued that the discovery will be helpful in better understanding colour blindness and how the human brain visualises colour. But it has also been contested because of its limited value. After all, what is a new colour when only a few people can see it? If not material or scientific value, olo certainly seems to add philosophical value to the understanding of the world. In a world given to viewing the Other in strict binaries of black and white, olo, with its blue-green timbre and contested existence, shows that there is always room for ambiguity. It also comes with a simple lesson: There is value in looking at things through someone else's eyes. You may just discover something new.
Hashtags

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles


NDTV
10-06-2025
- NDTV
Study Reveals Food Items That Can Slow Down Ageing Process
People say age is just a number, stay young at heart and enjoy life, but despite an optimistic approach, no one can stop the process of ageing. However, it can be slowed down with exercise and a balanced diet. Scientists have also investigated to understand how food can influence epigenetic ageing. Ageing is the process of becoming older, characterised by physical, biological and psychological changes that occur over time. Ageing can affect various aspects of life, including wrinkling, greying of hair, decreased strength and reduced mobility. Growing old also causes cellular ageing, DNA damage and hormonal shifts. What is epigenetic ageing? Epigenetic ageing refers to changes in gene expression that occur as we age, without altering the underlying DNA sequence. These changes can influence how our genes are turned on or off, impacting ageing and age-related diseases. Researchers led by first author Jamie L Villanueva from the University of Washington and the National University of Natural Medicine established a connection between epigenetic ageing and food. Ryan Bradley, corresponding author from the National University of Natural Medicine and the University of California, also contributed to the study, published in the journal Aging-US. The researchers have found that some plant-based foods with compounds called methyl adaptogens might lead to a decrease in epigenetic age. To conduct the study, the researchers analysed healthy men aged 50 to 72 years. They had previously completed an eight-week programme featuring a plant-based, nutrient-rich diet. They were also guided on exercise, sleep and stress management. Food items that are rich in methyl adaptogen Green tea, oolong tea, turmeric, rosemary, garlic and berries are rich in methyl adaptogen. Researchers found that those who ate higher amounts of such food experienced greater reductions in epigenetic age.


Time of India
08-06-2025
- Time of India
#48: The science-backed diet-and-fasting blueprint for a longer, healthier life
Dr. Nickhil Jakatdar has been working at the cutting edge of preventive health and longevity over the last 10 years with the 3 D's – data, doctors, and dietitians – to go from being diagnosed with heart disease at the age of 41, to now having all his blood markers and body measurements in the green and his epigenetic biological age at 41 while his chronological age is 51. With a Ph.D. in Electrical Engineering and Computer Science from UC Berkeley and more than 60 patents to his name, Dr. Jakatdar has always believed in a scientific, data driven and practical approach to solving problems. He has founded or run 5 startups in the areas of semiconductors, consumer mobile video and molecular diagnostics and serves on the Advisory Boards of the South Asian Heart Center in California, the Center for Information Technology Research in the Interest of Society (CITRIS), has been a TEDx speaker and has been the youngest recipient of the esteemed UC Berkeley Distinguished Alumni Award. LESS ... MORE 'What's the most effective diet and fasting framework that helps improve both lifespan and health span?' This is a question I get asked a lot, and one that I have spent many years trying to research and experiment with. With so many diets and fasting strategies out there, it's hard to separate trends from what's actually backed by science. In today's post #48, I provide my conclusions and recommendations, along with the clinical evidence supporting them. As always, while each of our bodies react differently and therefore need to be optimized for accordingly, the Evidence Based Medicine (EBM) studies I quote have been done across large populations. For those that want the conclusion without reading further, here they are: a) base your meals on Mediterranean principles, b) eat in a 10 AM–7 PM window, c) add in a once or twice a month 24 hour fast, and d) avoid extremes. A Quick Note on Evidence Based Medicine (EBM) Evidence-Based Medicine or EBM—the practice of making health decisions based on the best available scientific research out there. But not all the millions of studies published are equal, so scientists rank them by strength. Sort A = High-quality evidence (large, consistent clinical trials or meta-analyses). Most trustworthy. Sort B = Moderate-quality evidence (some good studies, but with mixed results or smaller scale). Sort C = Low-quality evidence (based on expert opinion, early trials, or animal studies). There is also a metric called I² (I-squared), which tells us how much the results vary across the numerous studies in a meta-analysis. I² < 25% means the different studies mostly agree = reliable evidence. I² > 50% means the different studies had different results = use with caution. Together, Sort level and I² help us separate what's truly proven from what's still speculative. This combination—EBM Sort A with I² < 25%—is what I consider the gold standard. When evidence meets that bar, it makes my short list. The clear winner: Mediterranean diet EBM Sort A, I² = 9% If there's one eating pattern that consistently wins across cultures and decades of studies, it's the Mediterranean diet. In a meta-analysis of over 1.5 million people, those who followed this diet saw a 9% reduction in all-cause mortality. The PREDIMED trial, one of the most robust dietary studies ever conducted, showed a 30% drop in cardiovascular events in participants eating a Mediterranean-style diet enriched with olive oil or nuts. The key ingredients of a Mediterranean diet include vegetables, legumes, olive oil, fish, nuts, whole grains—and very little sugar or processed food. It's sustainable, flavorful, and deeply rooted in how some of the world's healthiest populations eat. For those interested in the Indian version of the classic Mediterranean diet, check out the video interview I did with renowned clinical nutritionist, Dr. Geeta Dharmatti, on the Longevity Lab Community video meet series. If you want to watch snippets from the talk, you can do it here or join the Longevity Lab Community to watch the interview or to review the summary show notes Coupled with intermittent fasting (10am to 7pm eating window) EBM Sort A, I² = 22% Now let's talk about when you eat. I personally follow intermittent fasting (IF) with a 10 AM to 7 PM eating window, giving my body ~15 hours of fasting each night. This schedule fits my lifestyle while tapping into powerful metabolic benefits. In a 2020 meta-analysis with I² = 22%, IF was shown to significantly reduce fasting glucose, insulin, body weight, and inflammation—even without reducing calorie intake. That's a big deal. IF works not just because you eat less, but because you give your body time to rest, repair, and rebalance. IF activates AMPK (your cell's energy regulator) and suppresses mTOR (your body's growth and aging switch), while enhancing autophagy, the process of cleaning out damaged cellular parts. These pathways are at the core of what we know about aging and healthspan. If these words sound too scientific, don't worry about it. I'll be doing a post on explaining these in simple terms because an understanding of these mechanisms help with understanding how our bodies behave during fasting vs. when we are well fed, and both have important roles to play in longevity and healthspan. And/or calorie restriction (without malnutrition) EBM sort A, I² < 20% (CALERIE Trial) Calorie restriction (CR)—eating about 10%–15% fewer calories than your body burns—has been shown to extend lifespan in every species studied. In humans, the CALERIE trial found that two years of mild CR improved insulin sensitivity, lowered inflammation, and improved cardiovascular biomarkers—even among healthy, non-obese individuals. But it comes with caveats: reduced energy, muscle loss, and risk of nutrient deficiencies if you're not careful. For those of us over 50, it's essential to prioritize protein and strength training if exploring this strategy. Alternatively, intermittent fasting can deliver many of the same benefits without constant calorie counting. Diets with weak or mixed evidence Some popular diets just don't hold up under rigorous scientific review. I cover them as well so as to provide the rationale behind why they don't make the cut. Here's how they rank: 1. Ketogenic diet EBM sort B, I² = 38% Keto has proven benefits for epilepsy and can improve insulin resistance and weight loss in type 2 diabetes. But for healthy individuals focused on longevity, the evidence is thin. No long-term studies show a reduction in mortality or aging-related decline. High saturated fat intake, low fiber, and nutrient gaps are concerns. In short: therapeutic, but not necessarily longevity-enhancing for most reasonably healthy individuals. 2. Paleo/ carnivore diets EBM Sort B, I² > 40% These diets cut out processed food, which is good—but they also eliminate fiber-rich, longevity-promoting foods like legumes and whole grains. Most studies are short-term and observational. No strong Randomized Controlled Trials or RCTs support these diets for long-term healthspan. 3. Ultra-processed vegan diets EBM sort B, I² = 35%–50% Whole-food plant-based diets are associated with lower mortality and disease risk—when done right. But highly processed vegan diets (mock meats, sugary snacks) don't offer the same benefits. Quality matters more than the label. If you are on a vegan diet, make sure you keep a close eye on the quality of your carbs. My summarized recommendations: Here's what I follow—and recommend—if health span and longevity are your goals: Base your meals on Mediterranean principles: veggies, legumes, olive oil, fish, whole grains, and nuts. I don't eat much fish but I do have chicken (grilled usually) and some amount of unflavored, unsweetened yogurt. Eat in a 10am–7pm window to give your body time to repair overnight. While I follow a 15 hour fasting window, even a 12-14 hour window is fine. Make sure it's practical to fit within your lifestyle, but avoid eating too much after sunset, since our circadian rhythm is a big driver of hormone balance. Add in a once-a-month or twice-a-month 24 hour fast to trigger deeper autophagy and mitochondrial rejuvenation. It is critical to not overdo it to ensure no muscle mass loss, and to avoid thyroid dysregulation. Avoid extremes. Diets that exclude major food groups often don't stand up to long-term evidence. Final thought Longevity is about combining the best of what modern science and ancestral wisdom agree on—and doing it consistently. Eat well. Eat smart. Give your body time to recover. And build strength—this will stand you in good stead for decades to come. Facebook Twitter Linkedin Email Disclaimer Views expressed above are the author's own.


Time of India
29-05-2025
- Time of India
Study reveals six foods that are proven to reverse ageing
Image credits: Getty Images Age reversing is currently the north star of the health industry. Every health or age-conscious person, influencer and brand is working towards the goal in one way or another that they make sure to promote if deemed beneficial. The concept of reverse ageing is related to your biological age, which is the age of the body on a physical and cellular level and not on the basis of the years you have been alive. These two ages- chronological and biological, can be different and the less your biological age is the more healthy your body is and the more lifespan you have. Thus, people are always configuring ways to reduce their biological age and stay healthy. The interest in the concept has led to the popularity of influencers such as Bryan Johnson and Mel Robbins who claim to have perfected the esteemed process. Now, a study published in the Aging journal by researchers from the University of Washington and other institutions has suggested that a diet rich in plant-based foods containing natural substances called methyl adaptogens can potentially slow biological ageing. What foods aid reverse ageing? Image credits: Getty Images The team wanted to investigate how dietary choices influenced DNA methylation, a process that regulates gene activity without affecting the DNA sequence itself. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like 5 Books Warren Buffett Wants You to Read In 2025 Blinkist: Warren Buffett's Reading List Undo The more the DNA methylation in specific sites in the genome, the higher a person's biological age is. In the study, the authors followed 43, healthy middle-aged men from Portland, Oregon who had finished an 8-week program that focused on a plant-based nutrient-rich diet along with exercise, sleep and stress reduction. The results showcased that those who consumed food with more polyphenols which have antioxidants and anti-inflammatory properties helped decrease the biological age by interfering with enzymes involved in DNA methylation. The authors recommended the daily consumption of dark leafy greens, cruciferous vegetables like broccoli, cauliflower, cabbage, colourful vegetables, pumpkin and sunflower seeds, beets, lean meats, low-glycemic fruits like apples, grapefruit and cherries and a serving or more from the methyl adaptogen group. They also suggested avoiding dairy, grains, legumes and alcohol. 6 foods that reverse age The study mentioned six foods that the participants consumed that had powerful impacts on declining their biological age. These include: Berries Image credits: Getty Images A half a cup of berries consumed daily can go a long way in reversing your biological age. According to a study published in the National Library of Medicine, berries contain polyphenolic compounds that lower oxidative stress and inflammation and alter the signalling involved in neuronal communication. This helps prevent age-related deficits in cognitive and motor function. Rosemary Image credits: Getty Images The effects of rosemary on hair health and growth have come to major limelight in recent times with doctors and influencers recommending using the herb in oils and waters to treat damaged hair. Now, researchers recommend consuming half a teaspoon of rosemary every day to aid in reversing biological ageing. In a study published in the National Library of Medicine, it was stated that rosemary extracts increased lifespan extension, and AMPK activation and improved cognitive function. Turmeric Image credits: Getty Images Turmeric is called the golden spice for a reason. The condiment has healing properties which have been known for years. But now, researchers recommend eating half a teaspoon of turmeric daily as the main active substance inside it, curcumin has anti-ageing properties as it changes the levels of proteins involved in the ageing process such as sirtuins and AMPK and inhibits pro-aging proteins such as NF-κB and mTOR, as mentioned in a National Library of Medicine study . Garlic Image credits: Getty Images Eating 2 cloves of garlic daily is said to be beneficial in reverse ageing. The antioxidant properties in the herb help it to prevent cerebral ageing, inhibit platelet aggregation, and improve blood circulation and energy levels, as cited in a study published in the National Library of Medicine. Green Tea Image credits: Getty Images Two cups of green tea daily is advised to be consumed by the study authors. It is able to delay collagen ageing with the help of its antioxidant mechanism. Additionally, it suppresses melanin production too which makes it a popular anti-ageing remedy, as mentioned in the National Library of Medicine. Oolong Tea Image credits: Getty Images If you are one of those rare people who do not like green tea, then study authors recommend swapping it with Oolong tea. You can also drink both. 3 cups of oolong tea daily is advisable to drink. Oolong tea is made from the leaves of the camellia sinensis plant and is partially oxidised. One step to a healthier you—join Times Health+ Yoga and feel the change