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Amazon is poised to win in health care, says AllTrails co-founder Jeremy Cotter

Amazon is poised to win in health care, says AllTrails co-founder Jeremy Cotter

CNBC4 days ago

Jeremy Cotter, AllTrails co-founder and early Facebook employee, joins 'Closing Bell' to discuss YouRise Health, AI's impact on health care and much more.

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Transgene completes initial screening in Phase II part of TG4050 vaccine trial
Transgene completes initial screening in Phase II part of TG4050 vaccine trial

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Transgene completes initial screening in Phase II part of TG4050 vaccine trial

Transgene has completed the initial subject screening for the Phase II segment of its Phase I/II trial of individualised neoantigen therapeutic vaccine, TG4050, as a monotherapy in the adjuvant treatment of human papillomavirus (HPV)-negative squamous head and neck cancers. The vaccine is based on the myvac platform powered by its partner NEC's AI to enhance antigen selection. During the Phase I portion of the trial, all subjects treated with the vaccine remained disease-free post a minimum follow-up of two years, demonstrating clinical proof of principle. Translational data indicated that these subjects showed sustained T cell responses at 24 months. Meeting all trial endpoints, the findings were shared at the American Society of Clinical Oncology (ASCO 2025) annual meeting. The company anticipates completing the randomisation of all subjects in the Phase II part by the end of this year, after a second screening carried out post-surgery and adjuvant radiotherapy. Around 80 subjects who have completely responded to adjuvant therapy are expected to be enrolled and randomised in the Phase I/II trial. The first immunogenicity data from the Phase II part are projected to be available in the second half of 2026, with preliminary efficacy data anticipated in the second half of 2027. The trial is assessing the treatment benefits of the vaccine in individuals at risk of relapse. So far, 32 evaluable patients have been included in the Phase I part, with the Phase II continuing globally. Transgene chief medical officer Dr Emmanuelle Dochy said: 'Timely completion of first patient screening of the Phase II part of our Phase I/II trial is an important milestone for Transgene and brings us one step closer to providing a new treatment option for patients living with operable squamous head and neck cancer. 'With meaningful data readouts expected over the next two years, we are preparing to deliver important data for TG4050 and, at the same time, explore its wider potential. We are grateful to the patients, their families, investigators, and clinical staff whose commitment made this achievement possible.' "Transgene completes initial screening in Phase II part of TG4050 vaccine trial" was originally created and published by Clinical Trials Arena, a GlobalData owned brand. The information on this site has been included in good faith for general informational purposes only. It is not intended to amount to advice on which you should rely, and we give no representation, warranty or guarantee, whether express or implied as to its accuracy or completeness. You must obtain professional or specialist advice before taking, or refraining from, any action on the basis of the content on our site. Sign in to access your portfolio

The Low-Hanging Fruit That Can Transform Healthcare Today
The Low-Hanging Fruit That Can Transform Healthcare Today

Forbes

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The Low-Hanging Fruit That Can Transform Healthcare Today

Kamal Anand, chief product officer of TeleVox and Mosaicx, part of West Technology Group. In conversations across the healthcare industry, I see many healthcare leaders rightly focused on AI's long-term potential. But in doing so, they may overlook high-impact automation and digital engagement tools that can improve efficiency, reduce administrative burden and enhance patient experience and outcomes right now. I believe in the power of automation and AI as augmentation tools. The most effective technologies currently in healthcare aren't designed to take over for humans; they're built to support them. They help care teams focus on what they do best while offloading the repetitive, routine and administrative work that weighs them down. As a pragmatic product leader, I've seen firsthand that incremental improvements, particularly those powered by responsible AI and automation, can drive real, measurable impact. 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Cheetah Mobile First Quarter 2025 Earnings: CN¥1.10 loss per share (vs CN¥2.68 loss in 1Q 2024)
Cheetah Mobile First Quarter 2025 Earnings: CN¥1.10 loss per share (vs CN¥2.68 loss in 1Q 2024)

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timean hour ago

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Cheetah Mobile First Quarter 2025 Earnings: CN¥1.10 loss per share (vs CN¥2.68 loss in 1Q 2024)

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