Australia unleashes twin AI supercomputers in push to lead medical, climate research
Australia's AI supercomputing ambitions are hitting top gear, with two major launches unveiled this week that aim to supercharge research in medicine, climate science, and more.In Melbourne, La Trobe University has switched on the country's first AI supercomputer of its kind—a NVIDIA DGX H200 system—dedicated to transforming medical research.Located at NEXTDC's data centre in Tullamarine, the supercomputer is backed by $10 million from the Allan Labor Government.Minister for Economic Growth and Jobs Danny Pearson, who visited the site, said: 'Victoria is proud to be home to this supercomputer that will deliver more medical breakthroughs and improve healthcare for Victorians and people around the world.'
The system will enable the Australian Centre for Artificial Intelligence in Medical Innovation (ACAMI) to analyse large volumes of health data and complex 3D imaging in hours, drastically reducing research time for projects such as clinical trials, precision oncology, immunotherapy, and cardiovascular risk prediction.'The potential of AI in medical and biotech research is huge,' said La Trobe Vice-Chancellor Professor Theo Farrell.'The DGX H200 enables faster translation of research into clinical trials and personalised therapies.'The supercomputer will also support innovations in digital pathology and cancer relapse-risk prediction, with early projects including a partnership with The Florey Institute on rare neurological diseases such as Niemann-Pick type C.'The super processing performance of NVIDIA DGX H200 systems will help us explore more options and get results faster,' said Dr Ya Hui Hung from The Florey.Meanwhile, Monash University has announced its own major push into AI computing with MAVERIC—short for Monash AdVanced Environment for Research and Intelligent Computing.Backed by a AU$60 million (US$39 million) investment, the system will be built over the next two years, with activation expected in 2026.
According to the university, MAVERIC will 'fill a critical gap in Australia's high-performance computing infrastructure,' and position the institution as a 'leader in AI-driven research within the international higher education and research sector.'The platform will initially be used for early cancer detection, managing chronic diseases, empowering clinical trials, and accelerating drug discovery. It will also power climate change and planetary health research, analysing complex datasets related to air quality, Antarctic ecosystems, and the effects of heat on populations.'Investment in world-leading AI is a crucial step in supercharging our sovereign research capabilities,' said Monash Vice-Chancellor Sharon Pickering.'Monash is a well-established ecosystem of world-class researchers, health networks and partners with large-scale data and pre-identified massive research questions ready to be solved… Until now, the missing link has been the necessary compute infrastructure to fully maximise this opportunity,' she added.The university said MAVERIC will be powered entirely by renewable energy, aligning with its net-zero targets. It also plans to use the platform for training students in ethical, human-centred AI development across undergraduate and postgraduate levels.Monash already operates high-performance systems like M3 and MonARCH, comprising thousands of CPU cores and multiple GPU nodes.
Hashtags

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Yahoo
2 days ago
- Yahoo
Draig secures $140m for neuropsychiatric disorder therapies
Draig Therapeutics has secured £107m ($140m) in an oversubscribed Series A financing round to advance its portfolio of next-generation therapies to treat major neuropsychiatric disorders. The investment was led by Access Biotechnology and saw contributions from Canaan Partners, SR One, Schroders Capital and Sanofi Ventures. The round also included SV Health Investors as seed investors and intermediate capital group. The investment will be used to advance the company's lead candidate, DT-101, into Phase II trials for major depressive disorder (MDD). DT-101 was developed to facilitate alpha-amino-3-hydroxy-5-methyl-4-isooxazole-propionic acid (AMPA) receptor modulation while ensuring that safety is not compromised. This was evidenced by data from a Phase Ia programme involving more than 60 subjects, which showed target engagement through the magnetoencephalography technique. Draig was established through a partnership between Cardiff University's Medicines Discovery Institute and SV Health Investors. Access Biotechnology head Liam Ratcliffe stated: 'Despite numerous treatments available for neuropsychiatric disorders, a significant unmet need remains with many patients continuing to experience inadequate symptom relief and high rates of relapse. 'Draig's differentiated approach, which targets core mechanisms underlying these complex conditions, has the potential to deliver a real breakthrough for patients.' As well as advancing DT-101, the new capital injection will also support the progression of two gamma-aminobutyric acid type A (GABAA) receptor modulators towards clinical trials in 2026. These compounds have the potential for addressing a spectrum of neuropsychiatric disorders that currently lack adequate treatment options. Draig co-founder and executive chair and SV Health Investors operating partner Ruth McKernan stated: 'Making the best molecules to rebalance brain networks has been John and Simon's life work. It has been a professional highlight for me to be part of creating this hugely promising company too.' "Draig secures $140m for neuropsychiatric disorder therapies" was originally created and published by Pharmaceutical Technology, a GlobalData owned brand. The information on this site has been included in good faith for general informational purposes only. It is not intended to amount to advice on which you should rely, and we give no representation, warranty or guarantee, whether express or implied as to its accuracy or completeness. You must obtain professional or specialist advice before taking, or refraining from, any action on the basis of the content on our site.
Yahoo
3 days ago
- Yahoo
Rafael Holdings Announces Continuation of its Phase 3 Study for the Treatment of Niemann-Pick Disease Type C1 (NPC1) Following Independent Data Monitoring Committee (DMC) Review of Prespecified 48-Week Interim Data
Phase 3 TransportNPC study to continue based on the independent DMC review of safety and efficacy data at prespecified 48-week interim analysis Data on the investigational candidate Trappsol® Cyclo™ (hydroxypropyl-beta-cyclodextrin), indicates that it is well-tolerated and has a safety profile consistent with the previously completed phase 1 and 2 studies and ongoing phase 1 open-label extension study NEWARK, N.J., June 18, 2025 (GLOBE NEWSWIRE) -- Rafael Holdings, Inc. (NYSE: RFL; NYSE American: RFL-WT) announced today that its subsidiary Cyclo Therapeutics' 96-week pivotal phase 3 TransportNPC study evaluating intravenous (IV) Trappsol® Cyclo™ for the potential treatment of Niemann-Pick Disease Type C1 (NPC1) will continue based on the independent Data Monitoring Committee (DMC) review of safety and efficacy data at the prespecified 48-week interim analysis. Additionally, the Food and Drug Administration (FDA) has accepted the statistical analysis plan for the TransportNPC study. These developments underscore the company's continuing commitment to advancing its lead investigational candidate through late-stage clinical development to support global regulatory and commercial readiness. 'NPC is a rare, fatal, and progressive genetic disease, and there is a need for safe and effective treatment that addresses its root cause,' said Howard S. Jonas, CEO of Rafael Holdings. 'The recommendation made by the independent DMC to continue the study to 96 weeks, boosts our determination to the continued clinical evaluation of the potential of TrappsolCyclo as a systemic and neurological treatment option for people living with NPC1. We recently enhanced our financial position with the closing of a $25 million rights offering earlier this month which will support our strategic objectives.' 'It is a privilege to lead and continue the TransportNPC study, the most comprehensive, controlled pivotal study of an investigational therapy for NPC ever conducted in terms of patient size, global footprint, duration, and clinical outcomes,' commented N. Scott Fine, Chief Executive Officer of Cyclo Therapeutics. 'We are grateful to the study participants, their families, investigators, and clinical trial sites who are dedicated to this important research.' About Trappsol® Cyclo™ (hydroxypropyl-beta-cyclodextrin) Trappsol® Cyclo™ (hydroxypropyl-beta-cyclodextrin) is a first-in-class propriety cyclodextrin formulation administered intravenously (IV) that mobilizes lysosomal cholesterol. TrappsolCyclo is designed to directly impact the root cause of Niemann-Pick Disease Type C1 (NPC1) by mobilizing cholesterol from late-stage endosomes and lysosomes. TrappsolCyclo has also been shown to cross the blood-brain barrier after IV administration, suggesting that therapeutic concentrations are reached in the central nervous system over the infusion time window. The potential clinical significance of those concentrations will be evaluated based upon the results of the phase 3 TransportNPC study. About the TrappsolCylco Study Program The phase 3 TransportNPC study is a prospective, randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of TrappsolCyclo (hydroxypropyl-beta-cyclodextrin) administered intravenously (2000 mg/kg dose every 2 weeks) in patients aged 3 years and older with confirmed diagnosis of Niemann-Pick Disease Type C1 (NPC1) (CTD-TCNPC-301; NCT04860960). The TransportNPC study enrolled 94 patients in over 25 sites across 13 countries. The study duration is 96 weeks, an unblinded interim analysis was reviewed by an independent DMC when all patients reached 48 weeks and recommended to continue the study for the full 96 weeks. A phase 3 open-label extension study of up to 96 weeks follows the interventional study. The primary endpoints of the phase 3 TransportNPC study are the mean change in the 4-domain NPC Clinical Severity Scale (4D-NPC-CSS) score in the United States and the 5-domain NPC Clinical Severity Scale (5D-NPC-CSS) score in Europe. The 4D-NPC-CSS score (inclusive of ambulation, fine motor, speech, and swallow) and 5D-NPC-CSS score (inclusive of ambulation, fine motor, speech, swallow, and cognition) are measures of NPC disease progression that look at items that patients with NPC and their caregivers and physicians have identified as most relevant. Important secondary and exploratory endpoints will also be assessed across measures of disease activity. As part of the phase 3 study, a phase 3 open-label sub-study is being conducted in NPC1 patients from birth to 3 years of age outside of the United States. Ten patients have been recruited and are continuing in the study. Outcomes for the sub-study include safety, clinical, and caregiver impression of the disease. Cyclo Therapeutics has completed 2 studies, including a phase 1 study (CTD-TCNPC-101; NCT02912793) and a phase 2 study (CTD-TCNPC-201; NCT02912793). Patients who completed the phase 1 study continue to receive TrappsolCyclo treatment in the ongoing phase 1 open-label extension study (CTD-TCNPC-102; NCT03893071). About Niemann-Pick Disease Type C1 (NPC1) Niemann-Pick Disease Type C1 (NPC1) is a rare genetic disease that affects approximately 1 in 100,000 live births globally and often leads to premature death. NPC1 is characterized by an inability for cells to transport and process cholesterol, resulting in excessive amounts of cholesterol accumulating and damaging affected organs, including the liver, spleen, and brain. The disease can be life-limiting, with symptoms including progressive intellectual decline, loss of motor skills, seizures, and dementia. Approximately 95% of individuals with NPC have mutations in the NPC1 gene, and 5% have mutations in the NPC2 gene. About Rafael Holdings, Inc. Rafael Holdings, Inc. is a biotechnology company with interests in clinical and early-stage pharmaceutical companies including a 100% interest in Cyclo Therapeutics, LLC, a biotechnology company dedicated to developing Rafael's lead clinical candidate, Trappsol® Cyclo™ (hydroxypropyl-beta-cyclodextrin), which is being evaluated in clinical trials, including an ongoing phase 3 trial for the potential treatment of Niemann-Pick Disease Type C1 (NPC1), a rare, fatal, and progressive genetic disorder. Rafael also holds a majority interest in LipoMedix Pharmaceuticals Ltd., a clinical stage pharmaceutical company, Barer Institute Inc., a wholly owned preclinical cancer metabolism research operation, a majority interest in Cornerstone Pharmaceuticals, Inc., formerly known as Rafael Pharmaceuticals Inc., a cancer metabolism-based therapeutics company, a majority interest in Rafael Medical Devices, LLC, an orthopedic-focused medical device company developing instruments to advance minimally invasive surgeries, and a majority interest in Day Three Labs, Inc., a company which empowers third-party manufacturers to reimagine their existing cannabis offerings, enabling them to bring to market better, cleaner, more precise and predictable versions by utilizing Day Three's technology and innovation like Unlokt™. About Cyclo Therapeutics, LLC Cyclo Therapeutics, LLC ('Cyclo') is a wholly owned subsidiary of Rafael Holdings, Inc. (NYSE: RFL). Cyclo is a clinical-stage biotechnology company dedicated to developing life-changing medicines through science and innovation for patients and families living with rare and neurodegenerative diseases. The company's investigational drug Trappsol® Cyclo™ (hydroxypropyl-beta-cyclodextrin), an orphan drug designated product in the United States and Europe, is the subject of 4 formal clinical trials for Niemann-Pick Disease Type C1, a rare and fatal genetic disease, ( NCT02939547, NCT02912793, NCT03893071 and NCT04860960). Cyclo is also conducting a phase 2b clinical trial using TrappsolCyclo intravenously in early Alzheimer's disease (NCT05607615) based on encouraging data from an Expanded Access program for Alzheimer's disease (NCT03624842). Forward-Looking Statements This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this press release that do not relate to matters of historical fact should be considered forward-looking statements, including without limitation statements regarding our expectations surrounding the potential safety, efficacy, and regulatory and clinical progress of our product candidates; plans regarding the further evaluation of clinical data; and the potential of our pipeline, including our internal cancer metabolism research programs. These statements are neither promises nor guarantees, but involve known and unknown risks, uncertainties and other important factors that may cause our actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements, including, but not limited to, those disclosed under the caption 'Risk Factors' in our Annual Report on Form 10-K for the year ended July 31, 2024, and our other filings with the SEC. These factors could cause actual results to differ materially from those indicated by the forward-looking statements made in this press release. Any such forward-looking statements represent management's estimates as of the date of this press release. While we may elect to update such forward-looking statements at some point in the future, we disclaim any obligation to do so, even if subsequent events cause our views to change. Contact:Barbara 274-2825Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
5 days ago
- Yahoo
Raymond James Resumes Coverage on Disc Medicine (IRON) With a Strong Buy Rating
Disc Medicine, Inc. (NASDAQ:IRON) is one of the 10 Best Small-Cap Growth Stocks to Buy According to Analysts. On June 11, analysts from Raymond James resumed coverage of Disc Medicine, Inc. (NASDAQ:IRON) with a strong Buy rating and a price target of $89. The resumed coverage comes as the company released its research note on Biotech names. The firm highlighted a favorable risk/reward profile in the biotech sector. It noted that while companies with a high probability of success for lead assets inspire higher conviction, investments in less de-risked assets like Disc Medicine, Inc. (NASDAQ:IRON) could yield the most outsized returns. The firm sees more than $1 billion potential for the company's drug bitopertin, with an expected market penetration of about 30%-35%, owing to its disease-modifying agent capabilities X-linked protoporphyria. A scientist in a laboratory setting examining a sample of blood with a microscope. Disc Medicine, Inc. (NASDAQ:IRON) is a clinical-stage biopharmaceutical company focused on discovering therapies for serious hematologic diseases. Its pipeline includes drug candidates like bitopertin for erythropoietic porphyrias and Diamond-Blackfan Anemia, DISC-0974 for anemia related to myelofibrosis and chronic kidney disease, and DISC-3405 for polycythemia vera and other blood disorders. While we acknowledge the potential of IRON as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock. READ NEXT: The Best and Worst Dow Stocks for the Next 12 Months and 10 Unstoppable Stocks That Could Double Your Money. Disclosure: None. Sign in to access your portfolio