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Increased Movement Of People Making Dengue Outbreaks More Common, Says Mosquito Expert

Increased Movement Of People Making Dengue Outbreaks More Common, Says Mosquito Expert

Scoop09-06-2025

Greg Devine said mosquitos that carry the virus 'hitchhike around the world' and the increased movement of people is increasing those infected by dengue. Caleb Fotheringham, RNZ Pacific Journalist
Dengue fever outbreaks have been surging in recent decades but new initiatives like infecting mosquitos with bacteria or genetic modification could dramatically slow the spread.
According to the World Health Organization there was just over 500,0000 reported cases in 2000 – ballooning to 5.2 million in 2019.
Last year, there were 14 million dengue cases – a record number dwarfing the previous 2023 high of 6.5 million.
This year, there's been 2.5 million.
Samoa, Fiji, Tonga and the Cook Islands have all declared dengue outbreaks. Samoa, Fiji and Tonga have each had at least one death from the viral infection.
Greg Devine from the World Mosquito Program said increased globalisation is making outbreaks more common.
Devine said mosquitos that carry the virus 'hitchhike around the world' and the increased movement of people is increasing those infected by dengue.
Devine said a lot of people also don't have immunity.
'They don't have any protection against it because they've never been exposed to it before,' he said.
'Dengue comes in four different serotypes, so just because you've had one doesn't mean you can't get another.'
He said climate change was having an increasing impact.
'We are hotter and wetter than we've ever been before and that's great for mosquitoes. It also means that the virus in mosquitoes is replicating more rapidly.'
The aedes aegypti mosquito – which carries dengue – is considered a tropical or subtropical mosquito, but Devine said warmer weather would also increase the mosquitoes' range of where it inhabits.
In the Pacific, health ministries are trying to stamp out mosquito breeding grounds and are spraying insecticides outside.
But Devine said doing so has had limited success in reducing the spread.
He said the aedes aegypti mosquito is 'completely reliant upon humans for its blood meals' which meant it liked to stay indoors, not outdoors where the majority of the spraying happens.
'Outdoor use of insecticides, it's perhaps better than nothing and the truth is that the community wants to see something happening.
'That's a very visible intervention but the reality is, there's a very limited evidence base for its impact.'
Mosquitoes continually exposed to insecticides would also evolve resistance, Devine said.
The World Mosquito Programme infects mosquitos with a naturally occurring bacteria called Wolbachia, which stops viruses like dengue growing in the mosquitoes' bodies.
'It's been trialled in New Caledonia, where it's been extremely successful,' Devine said.
'In the years since, the mosquito releases have been made by the World Mosquito Program, there's been no dengue epidemics where once they were extremely common.'
He said genetically modified mosquitoes were also being looked at as a solution.
'That's a different kind of strategy, where you release large numbers of mosquitoes which have been modified in a way which means when those males interact with the local mosquito female population, the resulting offspring are not viable, and so that can crash the entire population.'
When asked if that could collapse the entire aedes aegypti mosquito population, Devine said he wouldn't be 'particularly worried about decimating numbers'.
'People often refer to it as the kind of cockroach of the mosquito world.
'It's very, very closely adapted to the human population in most parts of its range. The species evolved in Africa and has since, spread throughout the world. It's not a particularly important mosquito for many ecosystems.'

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Dr Prapti Gilada calls for raising awareness, health and treatment literacy among the masses so that eligible boys and men and girls and women can access HPV vaccination, HPV screening and management of pre-cancerous lesions and other health issues. She also hopes governments will make HPV vaccination available to all those eligible of all genders, as well as screening and appropriate management. Dr Prapti Gilada cites a study published in The Lancet in 2023 which showed that almost 1 in 3 men over the age of 15 were infected with at least one genital HPV genotype, and 1 in 5 men were infected with one or more of high risk (or oncogenic) HPV genotypes. It is high time all eligible boys and men too are included in HPV responses globally Agrees Vijay Nair who is the Chairperson of Udaan Trust and a prominent community rights activist from India: 'With no HPV vaccination and screening facilities for males, there are people who have even probably died with undiagnosed HPV-related anal cancers or other health issues. Some may be getting services for piles or anal fissures or fistula as there is hardly any HPV screening facilities for anal HPV. We need to screen high-risk men for HPV and HPV related health conditions including pre-cancerous lesions or anal cancers. Also, we need to include males too for vaccination against HPV.' Vijay was speaking at the India's National Dialogue and Stakeholder Consultation held last month in preventing cancers and addressing ageing among people living with HIV. It was organised by National Coalition of People Living with HIV in India (NCPI Plus). Colposcopy and anoscopy: Do we have enough facilities? Those with persistent HPV infection may need a specialised follow up medical examination with colposcopy (medical experts examine with an equipment for any HPV-related changes or abnormalities in vulva, vagina or cervix of women) or anoscopy (medical experts examine with an equipment for any HPV-related changes or abnormalities in anus or rectum). If any changes or abnormalities, further appropriate medical treatment is required. 'We need more medical centres for anoscopy,' said Dr Prapti Gilada whose study participants may require further follow up. Her centre is continuing to follow up with all the study participants, one of whom has become HPV negative during the study. Dr Smita Joshi is a widely recognised colposcopy trainer too. 'We have screened over 40,000 women for HPV and cervical cancer and managed them appropriately as per the WHO latest guidelines.' 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Achieving that goal rests on 3 key pillars and their corresponding targets to be achieved by 2030 so that countries are on track towards eliminating cervical cancer by end of the century. – vaccination: 90% of all eligible young people must be fully vaccinated with the HPV vaccine by the age of 15 – screening: 70% of women should be screened using a high-performance test by the age of 35, and again by the age of 45 – treatment: 90% of women with pre-cancer treated and 90% of women with invasive cancer managed. Cervical cancer is preventable as vaccines exist since almost two decades now. HPV screening and DNA tests exist. Medical management of pre-cancerous lesions can save lives and avert cancers. Is not a goal to eliminate cervical cancer by turn of this century, lacking ambition? 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The study involved leading Indian government's research institutes, including All India Institute of Medical Sciences (AIIMS) Delhi, ICMR National Institute for Cancer Prevention and Research (NICPR) Noida, and ICMR National Institute for Research in Reproductive and Child Health (NIRRCH) Mumbai, in collaboration with WHO's International Agency for Research on Cancer (IARC). However, Truenat HPV-HR DNA molecular test has been around for over 2 years now to screen people for 4 high-risk genotypes. Follow the science: Vaccinate and screen all eligible people for HPV and related cancers Dr Smita Joshi led several researchers in her distinguished career over two decades. She was part of a multi-centric study of WHO's IARC on HPV vaccine which was initiated in 2009 onwards. This study was to evaluate efficacy of HPV vaccine (2 doses vs 3 doses at 0, 2 and 6 months). However, due to government's order to stop HPV vaccination in studies (owing to adverse outcomes in a PATH study), Dr Joshi's study also had to stop vaccination abruptly in April 2009. 'Because of that suspension of HPV vaccinatio, instead of two versus three doses, this study resulted in a cohort of girls that had received only a single dose, two doses (at 0 and 2 months), two doses (at 0 and 6 months) and three doses (at 0, 2 and 6 months). So, the long-term follow-up of these vaccinated girls is still being carried out since then,' said Dr Joshi. 'We have now completed 15 years of the study and of immunogenicity data.' Dr Joshi's study majorly impacted and contributed to informing vaccine dosage in many countries as well as to WHO's recommendation of single dose HP vaccination in the young girls. She was also part of the HPV vaccine study (for India's indigenously developed HPV vaccine Ceravac). She wonders when HPV vaccine would become a part of Indian government's public vaccination programme. Some Indian states (like Sikkim, Delhi, Punjab) had introduced HPV vaccination using a foreign-made vaccine) but latest information on status of these programmes is not with us. Dr Prapti Gilada and Udaan's Vijay Nair too call for including HPV vaccination for those eligible from all genders in the government's programme at the earliest – as well as HPV screening and management of all related health conditions especially pre-cancerous lesions and cancers. Dr Smita Joshi adds that when government of India includes indigenously developed HPV vaccine in its programme, then 'one good thing about Ceravac of Serum Institute of India is that it is also approved for boys. Appeal to world leaders who will meet at UNHLM on NCDs Next High Level Meeting on Non-Communicable Diseases (UNHLM on NCDs) will happen in September 2025 at the United Nations General Assembly. Although HPV is an infection, yet it causes one of the top cancers worldwide. We appeal to world leaders to commit to scale up HPV vaccination for all those eligible (regardless of genders), and screen all eligible people (regardless of gender) for HPV and related pre-cancerous and cancerous conditions. Developing vaccine or point-of-care diagnostics is not enough but deploying them at point-of-need in the Global South is critical pathway towards increasing access to lifesaving services and improving HPV-related responses on the ground. Shobha Shukla – CNS (Citizen News Service) (Shobha Shukla is the award-winning founding Managing Editor and Executive Director of CNS (Citizen News Service) and is a feminist, health and development justice advocate. She is a former senior Physics faculty of prestigious Loreto Convent College and current Coordinator of Asia Pacific Regional Media Alliance for Health and Development (APCAT Media) and Chairperson of Global AMR Media Alliance (GAMA received AMR One Health Emerging Leaders and Outstanding Talents Award 2024). She also coordinates SHE & Rights initiative (Sexual health with equity & rights). Follow her on Twitter @shobha1shukla or read her writings here

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