Latest news with #inflammation

Health Line

4 hours ago

Health
Health Line

Stages of Crohn's Disease

Key takeaways Crohn's disease symptoms can be mild, moderate, or severe. It's a progressive disease, but its stages are hard to determine because each person's condition progresses differently. The earlier you treat and manage Crohn's, the more likely you are to reduce your chance of developing more severe symptoms. There's no cure for Crohn's disease, but medications and lifestyle changes can help manage the condition. This is why it's crucial to identify the disease when symptoms are still mild. Crohn's disease is a type of inflammatory bowel disease (IBD). It's considered a chronic condition, which means that you'll have it for your entire life. The exact cause of Crohn's is unknown. It most often develops in your late teens or 20s. Crohn's disease is marked by inflammation of the gastrointestinal (GI) tract. The inflammation can appear anywhere in the GI tract, from the mouth to the anus. What are the stages of Crohn's disease? Crohn's is a progressive disease that starts with mild symptoms and gradually gets worse. With mild to moderate Crohn's, you may experience diarrhea or abdominal pain, but you won't experience other symptoms or complications. You're able to move, eat, and drink as normal, and the disease has a minimal impact on your quality of life. In some cases, you won't even require treatment. If you have moderate to severe Crohn's disease, you may experience diarrhea or abdominal pain, as well as additional symptoms and complications, such as fever or anemia. If your Crohn's is severe, you might be in constant pain and discomfort, and you may need to use the bathroom frequently. That said, it's difficult to classify Crohn's disease into stages because people tend to experience ups and downs in symptoms. What progression looks like can be different for each person, and treatment can affect your outlook. How quickly does Crohn's disease progress? Over time, Crohn's can cause damage to the intestines and lead to potential complications such as strictures, fistulas, and abscesses. Stricture means that a portion of the intestine becomes narrower due to scar tissue on its wall. While there's no time frame for how long it would take for such complications to develop, there are risk factors that may speed up progression. These include: being under 30 years old having a history of smoking having ulcers found in a colonoscopy having the long bowel segments affected by the disease having anal inflammation having symptoms that go beyond the intestinal system, such as in the eyes, skin, liver, or joints having a history of bowel resections At diagnosis, 10% of people already have strictures, and an additional 15% to 20% will develop them within the next 10 to 20 years. Five types of Crohn's disease Progression may also depend on the type of Crohn's disease you have. These are: ileocolitis ileitis gastroduodenal Crohn's disease diffuse jejunoileitis Crohn's colitis Crohn's disease progression patterns The patterns by which Crohn's might progress are: Chronic relapsing: With this progression type, you typically experience at least 12 months of remission before experiencing a flare. Common symptoms of a Crohn's disease flare-up may include diarrhea, abdominal pain, weight loss, blood in stool, and fatigue. Remission: Remission means that your symptoms improve or disappear completely. Various studies show most people will relapse within 8 years of diagnosis, with a 43% to 45% remission rate after 10 years. But if you stay in remission for a year, there's an 80% chance remission will continue for the next year. Improved and stable: This is when your condition has progressed to having no symptoms and has remained this way, though signs of the disease might still show up on tests. Chronic refractory: This means you continue to show symptoms without any breaks or remission. About 10% to 15% of people with Crohn's experience a chronic refractory disease course. That said, even different people living with the same Crohn's pattern might progress differently. Genetics, type of treatment, and surgery are also factors that may affect which disease course you follow. The earlier you treat and manage Crohn's, the more likely you are to reduce your chance of developing more severe symptoms. What is the life expectancy of someone with Crohn's disease? There's no cure for Crohn's disease, though many people can live fulfilling lives with long periods of remission. That said, although there's been an increase in life expectancy for people living with inflammatory bowel diseases (IBDs), the life expectancy of Crohn's is still lower compared to those without IBDs for both males and females. When Crohn's causes complications, it can, in rare cases, lead to death. Common causes of death include cancer, heart disease, and infection. What are the early symptoms of Crohn's disease? In Crohn's disease, healthy cells in the GI tract attack themselves, causing inflammation. As a result, you'll likely experience a range of symptoms. Early signs of Crohn's disease include: frequent cramps ongoing abdominal pain frequent diarrhea bloody stools unintentional weight loss As the disease progresses, you may start feeling fatigued and even develop anemia. You may also experience nausea from constant irritation of the GI tract. In addition, you may start experiencing symptoms outside of the GI tract. These symptoms include: eye pain fever joint inflammation and pain red skin rashes and bumps mouth sores Early diagnosis is important to help prevent damage to the intestines. If you experience these symptoms and have a family history of Crohn's, you should ask your doctor for testing. How is Crohn's disease treated and managed? Medications can treat inflammation and stop your body from attacking its own cells. As your symptoms progress, your gastroenterologist may also recommend occasional bowel rest. However, not all doctors agree with this measure. A bowel rest involves a strict diet of only liquids for a few days. The purpose is to let the GI tract heal from inflammation and essentially take a break. To prevent malnutrition, you may need an IV. Talk with your doctor before switching to a liquid diet. Following this, your doctor may follow a special Crohn's diet and take supplements. You also may need to take pain medication. Avoid nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin), as these can make Crohn's worse. Instead, ask your doctor if you can safely take acetaminophen (Tylenol). You may need surgery if your symptoms become life threatening. Around 67% to 75% of all people with Crohn's will eventually need surgery, according to the Crohn's & Colitis Foundation. Surgery can't cure the disease, but it may help repair severely damaged tissues and remove blockages.

SlimJaro Advanced Weight Loss Supplement in 2025: Can Targeting Inflammation Extra Body Fat, Read Slim Jaro Benefits & Side Effects

Yahoo

5 hours ago

Health
Yahoo

SlimJaro Advanced Weight Loss Supplement in 2025: Can Targeting Inflammation Extra Body Fat, Read Slim Jaro Benefits & Side Effects

SlimJaro Supplement Focused Approach to Fat Burn and Weight Management in 2025 Slimjaro New York City, NY, June 20, 2025 (GLOBE NEWSWIRE) --In 2025, weight loss has become more complicated than simply cutting calories or hitting the gym. Many people around the world are following standard health advice yet still struggle with slow or stagnant results. A growing group of health researchers believe the answer may lie deeper — in inflammation. At the center of this shift is SlimJaro, a new inflammation-focused supplement that aims to help the body naturally release stored fat by targeting internal blockages rather than relying on extreme diets or stimulants. While traditional 'eat less, move more' advice still holds merit, new insights suggest that the body's ability to burn fat is not just about math — it's also about biology. Inflamed fat cells, hormone imbalances, chronic stress, and poor digestion may all play a role in keeping fat 'locked' in place, even when lifestyle changes are made. Why Weight Loss in 2025 Is Harder Than Ever Despite more awareness around healthy eating and exercise, obesity rates remain high across all age groups. Part of the reason is that weight loss has historically focused on symptoms (like appetite or cravings) rather than causes. But new science is revealing some hidden factors:Chronic Inflammation: When fat cells become inflamed — often due to stress, poor diet, environmental toxins, or metabolic syndrome — they can become 'resistant' to fat-burning signals. Cortisol and Insulin Spikes: High stress raises cortisol, which encourages fat storage, especially around the belly. Meanwhile, insulin spikes from processed food can prevent fat breakdown. Poor Digestion and Gut Health: An unbalanced gut microbiome, frequent bloating, or sluggish digestion may impair nutrient absorption and keep metabolism slow. Sleep and Hormones: Lack of sleep and irregular routines disrupt hormonal rhythms that govern hunger and fat storage. This complexity has led many to explore new types of support tools — not to replace diet and exercise, but to work with the body's deeper processes. What Is SlimJaro? According to the official product website (https::// SlimJaro is a U.S.- made, non-GMO dietary supplement designed to support weight management by calming inflammation in the body, particularly in fat tissue. Unlike fat burners loaded with caffeine or synthetic ingredients, SlimJaro relies on plant-based extracts that support metabolism, digestion, and hormone than acting as a quick fix, it aims to act gently over time — restoring balance to systems that are often overlooked in conventional weight loss Makes SlimJaro Different? SlimJaro's approach is unique for a few reasons:Targets Inflammation in Fat Cells: Uses anti-inflammatory compounds like Boswellia, MSM, and Reishi Mushroom to calm fat tissue and support fat release. Mild Thermogenic Effect: Ingredients like Ginger Root gently boost metabolic rate without causing anxiety or heart racing. Digestive Support: Aloe Vera and other plant compounds support gut function, helping reduce bloating and promote regularity. • Stress & Hormonal Balance: Adaptogens like Reishi Mushroom may help regulate cortisol levels, which are often elevated in those who experience stubborn ingredient was selected based on its potential to work with the body rather than against it — aiming to reduce the biological resistance many people face when trying to lose Ingredients and Their Functions Ingredient Primary Role MSM (Methylsulfonylmethane) Anti-inflammatory, supports detox and cell health. Helps release fat stored in inflamed cells. Ginger Root Powder Boosts mild thermogenesis, helps regulate appetite and digestion. Boswellia Serrata Reduces systemic inflammation and supports gut and joint health. Ganoderma Lucidum (Reishi) Modulates stress hormones like cortisol, improves immune balance. Aloe Vera Extract Supports digestion, eases bloating, promotes a healthy gut lining. Arnica Montana Enhances circulation, may support nutrient delivery and tissue recovery. Magnesium (from Epsom Salt) Supports nerve and muscle function, sleep, and blood sugar control. This formulation is manufactured in a GMP-certified and FDA-registered facility in the U.S., with third-party testing to ensure quality and safety. What the Science Suggests Emerging research supports the connection between inflammation and obesity. A 2024 review published in Frontiers in Endocrinology noted that 'chronic low-grade inflammation in adipose tissue plays a key role in obesity-related metabolic dysfunction.' When fat cells are inflamed, they hold onto stored lipids, making it harder to lose weight even with caloric claims to address this root cause. While more peer-reviewed studies are needed on the specific formulation, the individual ingredients have shown promise in early Real Users Are Saying Early adopters of SlimJaro report a mix of outcomes:Many users say they noticed less bloating, steadier appetite, and improved energy within the first 2–3 weeks. A few report modest fat loss, especially around the midsection, without changing their diet significantly. Others did not experience noticeable changes and suggest it works better when paired with healthy SlimJaro has earned attention for its lack of stimulant side effects — no racing heart, nausea, or insomnia, which are common with traditional fat Might Benefit from SlimJaro? SlimJaro Supplement may be worth exploring for individuals who:Struggle with weight loss despite eating healthy and exercising Have signs of chronic inflammation (joint pain, bloating, fatigue) Experience stress-related eating or cortisol imbalance Prefer a gentle, stimulant-free supplement that supports long-term healthOf course, it's always recommended to consult with a healthcare provider before starting any new supplement. Visit SlimJaro Official Website To Read More.. Final Thoughts on Slim Jaro Supplement: A New Path in Weight Management? While SlimJaro is not a miracle pill, its inflammation-centered approach represents a promising shift in how we think about body weight, metabolism, and wellness in 2025. As research continues to uncover the connections between inflammation, gut health, hormones, and fat storage, supplements like SlimJaro may serve as part of a more personalized and effective path to long-term weight and Contact InformationContact: Slimjaro Website: https::// Address: PO Box 90129, Lakeland, FL 33804, USA Phone: +1.833.746.6887 or +1.833.746.5587 Email: support@ -------- Contact Us for Advertising: rajneesh08verma@ Attachment Slimjaro CONTACT: Contact: Slimjaro Website: https::// Address: PO Box 90129, Lakeland, FL 33804, USA Phone: +1.833.746.6887 or +1.833.746.5587 Email: support@

‘My adult acne dictated my life for a decade – until I realised it was caused by stress'

Telegraph

a day ago

Health
Telegraph

‘My adult acne dictated my life for a decade – until I realised it was caused by stress'

The medical explanation for how how stress impacts skin This link between psychological stress and skin health is now well supported by science, says Dr Ahmed. Stress alters the immune response in the skin, increases inflammation, and disrupts the skin barrier – making it more reactive to heat, fragrance, pollution, even sweat. 'When you're stressed, the hypothalamic-pituitary-adrenal (HPA) axis is activated, flooding the body with cortisol, a hormone that slows down wound healing, reduces immunity, and increases inflammation,' Dr Ahmed explains. 'Even the microbiome on your skin changes under stress,' she adds. 'Because the skin itself contains its own stress response system – meaning that even over-cleansing or exposure to pollution can cause visible flare-ups. So stress is really not just in your head, it's in your actual cells. What's more, people don't realise, or perhaps forget, that your skin is a sensory organ, so it reflects how safe, or unsafe, your body feels.' Dr Ahmed believes several factors lie behind the rise in her patient numbers: burnout, increased screen time, poor sleep, dietary shifts, and the pressure of constant self-surveillance through social media. 'We're living in high-alert mode, and our skin is reflecting it,' she says. Taking a deeper, holistic approach In Kiara's case, it wasn't until she began working with a nutritionist that things started to shift. 'I'd dismissed nutrition as irrelevant,' she admits. 'But once we looked at my gut health, inflammation, and hormones – and yes, stress! – it all made so much more sense. Kiara also radically simplified her skincare routine – ditching aggressive acids and focusing on calming, barrier-supporting products instead. But, even more importantly, says Kiara, was shifting her mindset. 'It wasn't just about skin. I had to sort out the decade-long relationship I had with my self-esteem that was the very thing causing the stress and anxiety.' The emotional scars that last longer than the spots Interestingly, even when symptoms improve, patients often take far longer to recover emotionally, says Dr Ahmed. 'There's something we call 'psycho-lag,' where the skin clears before the person feels safe or confident again. They've lived with fear, shame, trauma. It doesn't vanish overnight. But it can be worked on.' For Kiara, the final turning point came when she began speaking openly about her experience. 'I started an Instagram account, initially anonymously, no face, just words. And the messages came flooding in from other sufferers: 'Me too', and 'I thought I was the only one.' That's when I realised this isn't just about skin – it's about connection, confidence, and finally being seen. That's instant stress relief.' Today, Kiara's confidence – and her complexion – is so vastly improved she's changed careers. After qualifying as a master NLP practitioner, the psychology graduate now works as a skin confidence coach, helping people with the mental and emotional scars of acne. 'Looking back, the most damaging part of my experience wasn't the spots themselves, but the lonely silence around them. No one talked about how spots made you feel, so I thought I was the only one dealing with it as an adult. I want to get the message out that talking helps relieve stress, and stress relief can only be a good thing for your skin.' How to support stressed skin Dr Alia Ahmed's evidence-based tips for protecting your skin during times of stress Sleep matters – as does timing Sleep deprivation elevates cortisol and delays healing. The skin regenerates overnight. Aim for seven to nine hours, starting before midnight, because your circadian rhythm matters, so eight hours starting at 2am is not the same as sleeping from 10pm. Your cortisol needs to drop for proper healing. Stay hydrated Aim for 1.5–2 litres of water daily. Not just for 'plump' skin, but for gut health, detoxification, and microbiome balance. I also recommend good fats (like omega-3s), probiotics, and vitamin D, especially in darker-skinned individuals, or during UK winters. Feed your skin from the inside There's actually no strong scientific evidence that chocolate or dairy directly cause skin conditions. But we do know high-glycaemic foods can trigger acne in some people. So if someone cuts something out and sees a difference – great. Just make sure they're replacing nutrients properly, and willing to reintroduce them if there's no improvement. Prioritise healthy fats (like omega-3s from fish or flax), fibre-rich vegetables, and probiotics or fermented foods to reduce inflammation Watch alcohol intake I don't say 'never drink, 'just be realistic. If you're flaring up, don't stack back-to-back nights out and then wonder why your face is inflamed. Alcohol is a clear trigger for rosacea and psoriasis, and it dehydrates the skin. But I'm no killjoy, live your life as you want to, just understand the consequences. Keep it simple Avoid aggressive acids or actives when your skin is inflamed. Stick to a gentle cleanser, barrier-repairing moisturiser, and daily SPF (sun protection factor). For Kiara, I advised Tolpa Sebio CICA night cream. Laser treatments More people are asking about these. AviClear is an FDA-approved treatment for acne which is available in the UK, and evidence has shown it can effective when used on its own, or alongside oral and topical treatments. I don't use it in clinic currently, although am looking into it. At-home red light treatments don't have as much research behind them yet, and can be expensive, so discuss with a professional before investing. Rethink how you relax You might think it's too 'woo woo,' but I do recommend journaling, breathwork, walking, or even ten minutes of solitude on your commute, because these things all help regulate the nervous system. Not everyone needs to meditate if they don't fancy it; but everyone needs to decompress. Ask the right questions If your skin condition is affecting your mental health, raise it with your GP. You can request integrated support or referral to psychodermatology services, where available. Don't suffer alone.

Woman 'with no Botox and fillers' shows rubbing frozen cucumber on face brightens skin: Does it really and is it safe?

Hindustan Times

2 days ago

Health
Hindustan Times

Woman 'with no Botox and fillers' shows rubbing frozen cucumber on face brightens skin: Does it really and is it safe?

Chances are you might have heard of the frozen cucumber skincare hack, a trending hack. Beauty influencer Amal K has tried it and shared the benefits in a May 15 Instagram video titled, 'I am 37 with no Botox (Botulinum toxin — often referred to by the brand name Botox) or fillers: Frozen cucumber edition.' Also read | Woman shows rubbing banana peel on face works like Botox for brightening skin: But does it? In the accompanying video, Amal demonstrated how using a frozen cucumber provides a natural, cooling sensation, leaving skin feeling refreshed. The cold temperature also reduces puffiness, soothes inflammation, and tightens pores, she added. She said, 'I am 37 years old, and I have never had Botox or fillers. One thing I do daily is an ice facial; but today, we are going to use a frozen cucumber. Before you start, make sure your face is nice and clean.' Amal added, 'Cucumber contains vitamin K, so it is just going to help curb the appearance of dark circle, help the lymphatic around your eyes and reduce the appearance of puffiness. We all love that, right? It also helps blood circulation, brightens your skin, minimises pores. After you are done, don't throw the whole cucumber, just cut the top little piece off and throw it in the freezer (For use again).' In her caption, she wrote: 'Frozen cucumber in the am.' A post shared by Amal K (@amalkzad) But does this frozen cucumber skincare hack actually work? In an interview with HT Lifestyle, Dr DM Mahajan, senior consultant, dermatology, Indraprastha Apollo Hospitals, said that 'frozen cucumber massage can offer some temporary benefits to the skin, but it's not a miracle solution'. He said, 'Cucumbers are rich in water, antioxidants, and vitamins like C and K, which can help soothe the skin and reduce puffiness especially when chilled or frozen. When applied cold, they help constrict blood vessels, which can reduce under-eye bags, calm inflammation, and make the skin feel tighter and fresher.' Dr Mahajan added, 'Massaging the face with frozen cucumber may give your skin an instant glow by improving blood circulation. The cooling effect also helps close pores and reduce redness, making your skin look smoother and more even-toned. Plus, the act of massaging whether with cucumber or a cold roller stimulates lymphatic drainage and reduces puffiness.' However, from a clinical point of view, Dr Mahajan said 'the effect is temporary'. 'Frozen cucumber does not treat deeper skin concerns like acne, pigmentation, or wrinkles. Also, if used directly on very sensitive or dry skin, the extreme cold may irritate or damage the skin barrier. Dermatologists recommend wrapping the frozen cucumber in a thin cloth before using it or letting it thaw slightly to avoid cold burns.' According to Dr Mahajan, 'frozen cucumber massage is safe for most people and can refresh the skin temporarily'. It's a nice home remedy for quick results before an event or to start your day, but it shouldn't replace your regular skincare routine, Dr Mahajan said and added, 'For long-term skin health and beauty, consistent cleansing, hydration, sun protection, and dermatologist-approved products are more effective. So yes, enjoy that chilled cucumber rub now and then, but don't expect it to replace your sunscreen or anti-ageing cream.' Note to readers: This article is for informational purposes only and not a substitute for professional medical advice. Always seek the advice of your doctor with any questions about a medical condition.

EXCLUSIVE Colon cancer has mysteriously exploded among young Americans. Now doctors have made a huge breakthrough

Daily Mail