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[Bio USA] GI Innovation unveils next-gen immunotherapy pipeline
[Bio USA] GI Innovation unveils next-gen immunotherapy pipeline

Korea Herald

time2 days ago

  • Business
  • Korea Herald

[Bio USA] GI Innovation unveils next-gen immunotherapy pipeline

BOSTON -- Korean biotech company GI Innovation showcased its next-generation growth strategy at Bio USA 2025 in Boston on Tuesday. Leading the presentation was Yun Nari, head of GI Innovation's clinical strategy, who introduced the company's new drug development pipeline and global business roadmap. A licensed pharmacist, Yun joined the company's board of directors in March and is expected to play a pivotal role in accelerating clinical decision-making, an essential function in GI Innovation's core business of clinical-stage drug development. A key highlight was the unveiling of GI-128, a novel immuno-oncology candidate that leverages macrophage engagement, an emerging target in next-generation cancer therapies. The company also spotlighted its trispecific antibody pipeline, designed to surpass the current generation of aPD-(L)1/VEGF bispecific antibodies, which are gaining significant traction in the global oncology space. 'This year's Bio USA is a premier platform that brings together leading global investors and pharmaceutical companies,' said Jang Myoung-ho, CEO and founder of GI Innovation. 'It presented the perfect opportunity to demonstrate the competitiveness of our pipeline and global expansion strategy. We plan to actively explore a variety of partnership opportunities, including technology licensing, co-development deals and strategic investments.' Meanwhile, the growing interest in aPD-(L)1/VEGF bispecific antibodies in the immuno-oncology sector has led to a surge in high-value deals. Bristol Myers Squibb recently entered into a licensing agreement with German biotech firm BioNTech, paying an upfront sum of approximately $1.5 billion, with the total deal valued at around $11.1 billion. Likewise, Merck & Co. signed a deal last year with China-based LaNova Medicines, worth $588 million upfront and up to $2.7 billion in milestone payments. Building on this trend, GI Innovation's trispecific antibody platform integrates the company's proprietary aPD-L1 antibody, a VEGF antibody and a macrophage engager into a single molecule. The design aims to overcome the therapeutic limitations of bispecific antibodies by stimulating a more robust immune response within the tumor microenvironment, the company explained.

AI-Powered Retail Media Platform PulseAd Enters $280B US Market with Seattle Operations
AI-Powered Retail Media Platform PulseAd Enters $280B US Market with Seattle Operations

Malaysian Reserve

time13-06-2025

  • Business
  • Malaysian Reserve

AI-Powered Retail Media Platform PulseAd Enters $280B US Market with Seattle Operations

Amazon Verified Partner Delivers 99% Customer Growth for Retail Brands, Including Global Electronics Giant and Leading K-Beauty Companies SEOUL, South Korea and SEATTLE, June 12, 2025 /PRNewswire/ — PulseAd, the AI-powered retail media platform, today announced its US market entry with Seattle operations. The move targets the rapidly growing $280 billion retail advertising market, where PulseAd's technology has already delivered 99% increases in new customer acquisition for retail brands. Strategic Market Entry Targets Retail Media Boom Founded in March 2024, PulseAd has established its US headquarters in Seattle to capitalize on the retail media explosion reshaping digital advertising. With retail media generating over $150 billion in 2024 and projected to reach $280 billion by 2027, PulseAd's timing addresses the critical need for sophisticated campaign optimization tools. 'We're entering the North American market with technology that has demonstrated measurable results during the most competitive shopping periods,' said David Yun, CEO of PulseAd. 'Our Seattle presence enables us to work directly with US retailers as retail media becomes the third major wave in digital advertising, following search and social.' Proven Results Challenge Industry Giants PulseAd's clients, including a global electronics giant and prominent K-Beauty brands expanding into North American markets, have achieved performance improvements that exceed industry benchmarks: 99% increase in new customer acquisition 61% increase in repeat customer purchases 1,500% increase in sales during Amazon Prime Day through strategic traffic acquisition and keyword optimization 23% increase in overall brand repurchase rates These results position PulseAd's AI-first approach as a direct challenge to billion-dollar US AdTech giants retrofitting AI capabilities into legacy platforms. AI-First Platform Disrupts Traditional AdTech PulseAd differentiates itself through a comprehensive managed service approach that redesigns campaign management from the ground up. Unlike traditional agencies managing campaigns manually or existing platforms requiring extensive in-house expertise, PulseAd directly manages campaigns using AI-driven processes built specifically for retail media optimization. 'Most US players are either traditional agencies without technology depth or legacy platforms adding AI features to existing infrastructure,' explained Yun. 'We've architected our entire platform around AI from day one, similar to how Tesla built electric vehicles from scratch rather than converting combustion engines.' The platform integrates Amazon, Google, Meta, and TikTok, allowing retailers to manage and compare performance across all channels in one unified dashboard—critical as brands increasingly use external media to drive marketplace sales. Leadership Team and Technology Expansion PulseAd's leadership combines proven e-commerce and advertising technology expertise. CEO David Yun previously managed $1.3 billion in annual GMV at a major e-commerce platform(Kakao) and served as APAC Sales Director for a Silicon Valley advertising platform. CTO Kyle Choi brings engineering expertise in scalable data infrastructure, while COO Jay Kim contributes advertising operations experience from Google and other major AdTech companies. Building on existing integrations, PulseAd plans to add support for major US platforms including Walmart, Target, and Instacart during the second half of 2025. The company is also developing 'Pulsy', an AI assistant tool for campaign optimization and performance analysis. Capturing Massive Market Opportunity The US e-commerce advertising market represents unprecedented opportunity, with retail media as the fastest-growing segment. Amazon alone generates over $50 billion in annual advertising revenue, while platforms including Walmart and Target rapidly scale their advertising offerings with double-digit growth rates. 'Retail media provides superior attribution and ROI measurement compared to traditional digital channels,' said Yun. 'Brands are shifting significant budgets from search and social to retail media because they can directly measure sales impact rather than just engagement metrics.' PulseAd's expansion follows a systematic approach: the company will connect with major North American platforms beginning during the second half of 2025, focusing on maximizing advertising performance through AI-driven optimization and transforming marketer workflow efficiency. About PulseAd PulseAd provides AI-powered e-commerce advertising solutions as a retail media platform. As an Amazon Verified Partner and the first Korean company to achieve this status, PulseAd helps retailers optimize advertising performance across multiple platforms, serving brands in beauty, electronics, lifestyle, and consumer goods categories. For more information, visit

AI-Powered Retail Media Platform PulseAd Enters $280B US Market with Seattle Operations
AI-Powered Retail Media Platform PulseAd Enters $280B US Market with Seattle Operations

Korea Herald

time12-06-2025

  • Business
  • Korea Herald

AI-Powered Retail Media Platform PulseAd Enters $280B US Market with Seattle Operations

Amazon Verified Partner Delivers 99% Customer Growth for Retail Brands, Including Global Electronics Giant and Leading K-Beauty Companies SEOUL, South Korea and SEATTLE, June 13, 2025 /PRNewswire/ -- PulseAd, the AI-powered retail media platform, today announced its US market entry with Seattle operations. The move targets the rapidly growing $280 billion retail advertising market, where PulseAd's technology has already delivered 99% increases in new customer acquisition for retail brands. Strategic Market Entry Targets Retail Media Boom Founded in March 2024, PulseAd has established its US headquarters in Seattle to capitalize on the retail media explosion reshaping digital advertising. With retail media generating over $150 billion in 2024 and projected to reach $280 billion by 2027, PulseAd's timing addresses the critical need for sophisticated campaign optimization tools. "We're entering the North American market with technology that has demonstrated measurable results during the most competitive shopping periods," said David Yun, CEO of PulseAd. "Our Seattle presence enables us to work directly with US retailers as retail media becomes the third major wave in digital advertising, following search and social." Proven Results Challenge Industry Giants PulseAd's clients, including a global electronics giant and prominent K-Beauty brands expanding into North American markets, have achieved performance improvements that exceed industry benchmarks: These results position PulseAd's AI-first approach as a direct challenge to billion-dollar US AdTech giants retrofitting AI capabilities into legacy platforms. AI-First Platform Disrupts Traditional AdTech PulseAd differentiates itself through a comprehensive managed service approach that redesigns campaign management from the ground up. Unlike traditional agencies managing campaigns manually or existing platforms requiring extensive in-house expertise, PulseAd directly manages campaigns using AI-driven processes built specifically for retail media optimization. "Most US players are either traditional agencies without technology depth or legacy platforms adding AI features to existing infrastructure," explained Yun. "We've architected our entire platform around AI from day one, similar to how Tesla built electric vehicles from scratch rather than converting combustion engines." The platform integrates Amazon, Google, Meta, and TikTok, allowing retailers to manage and compare performance across all channels in one unified dashboard—critical as brands increasingly use external media to drive marketplace sales. Leadership Team and Technology Expansion PulseAd's leadership combines proven e-commerce and advertising technology expertise. CEO David Yun previously managed $1.3 billion in annual GMV at a major e-commerce platform(Kakao) and served as APAC Sales Director for a Silicon Valley advertising platform. CTO Kyle Choi brings engineering expertise in scalable data infrastructure, while COO Jay Kim contributes advertising operations experience from Google and other major AdTech companies. Building on existing integrations, PulseAd plans to add support for major US platforms including Walmart, Target, and Instacart during the second half of 2025. The company is also developing "Pulsy", an AI assistant tool for campaign optimization and performance analysis. Capturing Massive Market Opportunity The US e-commerce advertising market represents unprecedented opportunity, with retail media as the fastest-growing segment. Amazon alone generates over $50 billion in annual advertising revenue, while platforms including Walmart and Target rapidly scale their advertising offerings with double-digit growth rates. "Retail media provides superior attribution and ROI measurement compared to traditional digital channels," said Yun. "Brands are shifting significant budgets from search and social to retail media because they can directly measure sales impact rather than just engagement metrics." PulseAd's expansion follows a systematic approach: the company will connect with major North American platforms beginning during the second half of 2025, focusing on maximizing advertising performance through AI-driven optimization and transforming marketer workflow efficiency. About PulseAd PulseAd provides AI-powered e-commerce advertising solutions as a retail media platform. As an Amazon Verified Partner and the first Korean company to achieve this status, PulseAd helps retailers optimize advertising performance across multiple platforms, serving brands in beauty, electronics, lifestyle, and consumer goods categories.

Macquarie Keeps Their Buy Rating on Pilbara Minerals (PILBF)
Macquarie Keeps Their Buy Rating on Pilbara Minerals (PILBF)

Business Insider

time12-06-2025

  • Business
  • Business Insider

Macquarie Keeps Their Buy Rating on Pilbara Minerals (PILBF)

In a report released today, Austin Yun from Macquarie maintained a Buy rating on Pilbara Minerals (PILBF – Research Report), with a price target of A$2.40. The company's shares closed yesterday at $0.92. Confident Investing Starts Here: According to TipRanks, Yun is an analyst with an average return of -13.0% and a 45.00% success rate. Yun covers the Basic Materials sector, focusing on stocks such as Pilbara Minerals , Lynas Rare Earths , and Sayona Mining. In addition to Macquarie, Pilbara Minerals also received a Buy from Morgan Stanley's Rahul Anand in a report issued today. However, on May 30, UBS downgraded Pilbara Minerals (Other OTC: PILBF) to a Sell. Based on Pilbara Minerals 's latest earnings release for the quarter ending December 31, the company reported a quarterly revenue of $425.68 million and a GAAP net loss of $69.37 million. In comparison, last year the company earned a revenue of $757.23 million and had a net profit of $220.15 million

How Korea's next leader should set foreign policy compass
How Korea's next leader should set foreign policy compass

Korea Herald

time30-05-2025

  • Politics
  • Korea Herald

How Korea's next leader should set foreign policy compass

JEJU ISLAND -- The crux of the new Korean government's foreign and security strategy, former foreign ministers said, must be adapting to a shifting, more inward-looking US -- one demanding greater burden-sharing from its allies under President Trump's 'America First' doctrine -- while keeping the alliance at the core of its foreign policy at this critical crossroads. Facing a wave of increasingly interconnected global crises and a more inward-looking Washington, the former top diplomats urged Seoul's next leadership to move beyond the conventional US-centric approach and adopt a more holistic, big-picture foreign policy suited to the shifting global order. 'What's most important as Korea's new government takes office is that we are facing not just one or two challenges, but a complex web of simultaneous crises. We all know that these issues are unfolding on multiple fronts at once,' former Foreign Minister Yun Byung-se, who served under the former conservative Park Geun-hye administration, said during Thursday's session at the Jeju Forum held on the southern island of Jeju. 'Therefore, the new administration should not approach strategy solely through the lens of relations with the US, but should instead adopt a broader, more comprehensive perspective,' Yun said during a session on South Korea's diplomatic and security strategy ahead of the early presidential election on June 3. With no transition period before taking office, the new South Korean leadership will also need to quickly find its footing as it responds to growing US calls for greater responsibility in national and regional defense, as well as increased demands across the board within the bilateral alliance framework, Yun said. He also noted that, unlike in the past when North Korea's provocations were the main concern for an incoming administration, this time will be different: "the new government will need to prioritize how quickly it can formulate its own position in response to US priorities." 'Ultimately, it comes down to two main points: the role of US Forces Korea and South Korea's own regional role,' Yun explained. In Seoul, concerns are growing that the operational scope of US Forces Korea could extend beyond the Korean Peninsula and expand to regional defense, including being repurposed for a potential Taiwan contingency. 'In 2003, some units from US Forces Korea were redeployed to Iraq. Now, if they are redeployed -- not to Iraq, but to areas near Taiwan -- that could present a whole new set of challenges, and it's something we need to think about very carefully,' Yun said. 'From what I see, neither (presidential election) camp is fully prepared to address this issue yet.' Both the classified 'Interim National Defense Guidance,' as reported by The Washington Post, and Secretary of Defense Pete Hegseth's statement on the development of the 2025 National Defense Strategy make clear that US forces will prioritize deterring China as the sole pacing threat. Another key point is that allies should shoulder more responsibility for defending against other regional threats -- for South Korea, this means threats posed by North Korea. Former Foreign Minister Song Min-soon underscored that 'Korea needs to transform its current alliance system -- which is now overly dependent on the US -- into a more autonomous alliance, while still faithfully upholding the Korea-US alliance.' "This is something the US also wants," Song said. "However, in Korea, there is a fear that moving toward a more self-reliant alliance could lead to isolation from the US, and how to overcome that fear is the challenge." Song, who served in the former liberal Roh Moo-hyun administration, also called for the next South Korean government to 'more actively explore ways to achieve a nuclear balance between the two Koreas,' instead of merely relying on US extended deterrence. Extended deterrence refers to Washington's commitment to deter or respond to coercion and external attacks on its allies and partners with the full range of its military capabilities, including nuclear weapons. 'However, it doesn't necessarily mean that we need immediate nuclear armament,' Song continued. Former Foreign Minister Kim Sung-hwan, however, said the next government should continue to focus on diplomacy with the United States and ensure that US extended deterrence is well maintained, opposing the idea of South Korea independently seeking a nuclear balance against North Korea. On the diplomatic front, Kim emphasized that the key challenge is how to navigate between the Korea-US alliance and China amid the shifting global order. "From the perspective of our diplomatic and security interests, regardless of who becomes the next president, the most important point is what stance South Korea should take between the US, our ally, and China, given our geopolitical realities," Kim said. "This remains our greatest diplomatic challenge." But Kim also pointed out that the US is no longer willing to unilaterally provide public goods as it did in the past, as it needs to focus its limited capacity on addressing mounting domestic challenges. Kim, who served under former conservative President Lee Myung-bak, expressed his concerns over a potential return to what's known as the 'Kindleberger Trap,' highlighting this as a key factor for South Korea to consider in devising its foreign policy. The trap refers to the failure of the international system due to the under-provision of global public goods and the dangers inherent in a shifting balance of power. "Looking at the current global order, if the US stops providing public goods, who will take on that role? Is Europe economically strong enough to take on that responsibility?" Kim said. "These are the kinds of questions we need to seriously consider in the context of international affairs."

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