Latest news with #Trazodone
Miami Herald
a day ago
- Entertainment
- Miami Herald
Goofy dog kept returning to shelter for being ‘too playful.' Then came good news
A goofy dog kept returning to a North Carolina shelter for being 'too playful' — then came good news. The 1-year-old pup, known for his love of splashing in the pool, has now been adopted into a new home. 'We are hopeful that this time's the one for him,' Samantha Ranlet, a spokesperson for the Society for the Prevention of Cruelty to Animals (SPCA) of Wake County, told McClatchy News in a June 20 email. 'They've renamed him Nova.' The dog — originally named DJ — first landed at the SPCA after he was transferred from another facility. Although the Raleigh-area shelter doesn't know much about his background, he was anxious upon arrival. 'We've discovered that he's much happier on a medication called Trazodone,' the shelter wrote in a Facebook post. 'These meds help him go from a frightened fella that hunches and startles at the sound of a door opening to a lively, playful pup.' DJ was adopted twice, but the situations didn't work out. Both times, his playful nature was too much for the other animals in his homes. 'He wants to be friends sooooo badly, but unfortunately his high energy, goofy antics, and in-your-face play style haven't meshed well with calmer companions,' the SPCA wrote after his latest return on June 17. 'He's a spirited dork which isn't the right fit for everyone, we get it! Now he's back here with us and we are on a mission — to find him a forever home and a dork-tastic animal friend who can keep up with his little-legged zoomies!' At the shelter, DJ became known as a mixed-breed dog who enjoys snuggling. He also has a more 'fun-loving' side that shows up when he's outdoors, according to an online adoption profile and a video shared on Facebook. 'He's the type of dog that's always smiling with his tongue hanging out,' Ranlet wrote. 'He's friends with everybody, and he's the first to greet new people and soak up some attention. He absolutely loves water. Our staff takes him out for play time in the kiddie pool, and he loses his mind — gator rolling, jumping and splashing around, with just the biggest smile on his face.' Then, two days after DJ came back to the shelter, he was adopted for a third time. McClatchy News has asked for more details about the latest adoption and is awaiting a response.
Daily Record
13-06-2025
- Daily Record
'Lazy' girlfriend caught by horror mistake after strangling and decapitating ex
Taylor Schadbusiness was already known to police but no one could predict the sickening act she would comment. An evil mum brutally murdered and decapitated her ex-boyfriend whilst her drug-dealing husband served time behind bars. Taylor Schadbusiness was already known to police but no one could predict the sickening act she would comment. The mum to a two-year-old boy lived in Green Bay, Wisconsin, and was married to husband Warren. The pair had been together since 2017, but by 2022 Warren was serving time in prison for distributing drugs. Whilst Warren was in prison, Schabusiness spiralled out of control developing a drug habit. She'd been in trouble for evading the police and was on probation, The Mirror reports. Shad who was a kind and compassionate man, reportedly became swept along by Schadbusiness' strong character. On the evening of February 21, 2022, Schadbusiness picked up Shad from his mum's house, where he lived. The pair then headed off to a friend's house party. Two days later on February 23 Shad's mum, Tara Pakanich, made a horrifying discovery. She had assumed that her son and Schadbusiness were still in the basement where her son slept. However, that morning, she heard a door slam and the sound of a vehicle driving away. Tara went down to check on Shad but she couldn't see him. Then, at the bottom of the basement stairs, she made a gruesome discovery - her son's severed head in a bucket. After a hysterical 911 call, the police arrived at the house just after 3am. They found the plastic bucket covered with a towel. When the towel was lifted, there was Shad's head along with his dismembered penis. Officers made more gruesome discoveries as they searched the basement. There was blood on a mattress, more body parts and organs stuffed in plastic bags and boxes. Shad's torso was in a tote bag with one of his feet - and a carving knife. It was clear that Shad had been murdered in the basement and dismembered. Schabusiness was the last person to be seen with Shad and investigators hunted her down to the minivan where she was living. Her clothes were covered in blood, and she had scratches and a cut on her thumb that had been caused by a knife. In the van were more of Shad's body parts, including his leg. Schabusiness was arrested and taken for questioning. At first, she said she'd blacked out while partying with Shad. When she was asked about Shad's head in the bucket, she responded, "That is pretty f***ed up." Schabusiness was then recorded making a shocking confession. She said that after smoking cannabis with friends, she'd gone with Shad back to his mum's house where she claimed they'd smoked methamphetamine. She also said she had injected herself and Shad with the sedative Trazodone. In the basement, the couple started to have sex. She said they'd previously engaged in erotic asphyxiation, so Shad was allegedly a willing participant when Schabusiness put a chain around his neck and tightened it. She told the police that Shad started to cough up blood, but that she could feel his heart beating so she"kept pulling and choking him harder". She continued strangling Shad for three to five minutes until he was dead. She admitted she had "liked it" and asked officers if they "knew what it was like to love something so much that you kill it". Hiding his organs Instead of calling the police, or fleeing the scene, Schabusiness continued to perform oral sex on Shad, and use sex toys on his body for several hours. The next morning, she found knives in the house and used them to dismember Shad's body. She said a bread knife was best due to the serrated blade. Schabusiness described how she'd positioned his body on the mattress and beheaded him over the bucket. She poured blood down a shower drain and removed organs. She admitted enjoying beheading Shad, but went on to say she'd "got lazy" as she had intended to take his body parts to her minivan. She was calm as she described the killing. At one point she said, "Damn the head. I can't believe I left the head, though." Then she laughed as she said the police were "going to have fun trying to find all of the organs". Schabusiness would eventually plead not guilty by reason of insanity, but a judge ruled that she was competent to stand trial. At one of her hearings, she attacked her lawyer. At the trial this year, defence lawyers argued that Schabusiness had suffered from years of drug abuse and trauma, including the death of her mother when she was young, and imprisonment of her dad for sexual assault on a minor. They said her mental illness meant she wasn't capable of understanding her actions. But the prosecution told the court about the cold-blooded killing. How she'd sexually abused Shad's corpse then mutilated him. In the lead up to the killing, Schabusiness had researched the Wisconsin serial killer Jeffrey Dahmer and had admitted to a psychologist that she "had a thing" for him. She even had pictures of him on her phone. In July, Schabusiness, now 25, was found guilty of murder, third-degree sexual abuse and mutilating a corpse. Two months later, she was sentenced. Join the Daily Record WhatsApp community! Get the latest news sent straight to your messages by joining our WhatsApp community today. You'll receive daily updates on breaking news as well as the top headlines across Scotland. No one will be able to see who is signed up and no one can send messages except the Daily Record team. All you have to do is click here if you're on mobile, select 'Join Community' and you're in! If you're on a desktop, simply scan the QR code above with your phone and click 'Join Community'. We also treat our community members to special offers, promotions, and adverts from us and our partners. If you don't like our community, you can check out any time you like. To leave our community click on the name at the top of your screen and choose 'exit group'. If you're curious, you can read our Privacy Notice. A risk to the public Shad's uncle Kelly Thyrion insisted there should be no chance of parole. "I will pray that you meet the same fate as your idealistic Jeffrey Dahmer," he said, referring to his murder by another inmate behind bars. Incredibly, Shad's dad Michael said that Schabusiness should be given a chance. "I forgive you..." he said. "It does no good to hate you." Schabusiness was given life in prison without the chance of parole for the murder and an additional 10 and a half years for mutilation of a corpse and sexual assault. She appeared to smile and pull faces from beneath a large white mask, known as a spit hood to prevent spitting or biting. The judge said Schabusiness was a risk to the public. "This crime offends human decency, it offends human dignity, and it offends the human community." From prison, Schabusiness' husband Warren made a statement saying he was imprisoned because he'd been framed - and added that he'll stand by his wife "forever". Schabusiness is behind bars and Shad's murder has become a series of shocking headlines. A young man lost his life in the most senseless and brutal way, while his killer continues to show no remorse.
Daily Mirror
13-06-2025
- Daily Mirror
Monstrous woman continued to have sex with ex-boyfriend's butchered body
Taylor Schabusiness killed her lover while they were having sex - but what she did to him next defies belief Taylor Schabusiness had already crossed paths with the police, but no one could have predicted the gruesome act she would commit. Schabusiness lived in Green Bay, Wisconsin, and was married to husband Warren. They'd been together since 2017, but by 2022, Warren was serving time in prison for distributing drugs. The couple had a two-year-old son, who was living with family in Texas, and Schabusiness had developed a drug habit. She'd been in trouble for evading the police and was on probation. But while her husband was behind bars, she was partying and having sex with her ex-boyfriend, Shad Thyrion, 24. READ MORE: Daughter, 19, who bludgeoned mum to death with frying pan was hiding huge secret Shad was a kind, compassionate man who loved camping and spending time with family. He was swept along by Schabusiness' strong character. Gruesome discoveries On the evening of 21 February, 2022, Schabusiness picked up Shad from the house he lived in with his mum, and the pair went round to a friend's house to party. Shad's mum, Tara Pakanich, spent the next day out with her boyfriend and didn't see her son when she returned, as he slept in the basement. She assumed he'd spent the day with Schabusiness as her minivan was parked outside. But in the early hours of 23 February, she heard a door slam and the sound of a vehicle driving away. Tara went down to check on Shad but couldn't see him. Then, at the bottom of the basement stairs, she made a horrifying discovery - her son's severed head in a bucket. After a hysterical 911 call, the police arrived at the house just after 3am. They found the plastic bucket covered with a towel. When the towel was lifted, there was Shad's head along with his dismembered penis. Officers made more gruesome discoveries as they searched the basement. There was blood on a mattress, more body parts and organs stuffed in plastic bags and boxes. Shad's torso was in a tote bag with one of his feet - and a carving knife. It was clear that Shad had been murdered in the basement and dismembered. Schabusiness was the last person to be seen with Shad and investigators hunted her down to the minivan where she was living. Her clothes were covered in blood, and she had scratches and a cut on her thumb that had been caused by a knife. In the van were more of Shad's body parts, including his leg. Schabusiness was arrested and taken for questioning. At first, she said she'd blacked out while partying with Shad. When she was asked about Shad's head in the bucket, she responded, "That is pretty f***ed up." Schabusiness was then recorded making a shocking confession. She said that after smoking cannabis with friends, she'd gone with Shad back to his mum's house where she claimed they'd smoked methamphetamine. She also said she had injected herself and Shad with the sedative Trazodone. In the basement, the couple started to have sex. She said they'd previously engaged in erotic asphyxiation, so Shad was allegedly a willing participant when Schabusiness put a chain around his neck and tightened it. She told the police that Shad started to cough up blood, but that she could feel his heart beating so she "kept pulling and choking him harder". She continued strangling Shad for three to five minutes until he was dead. She admitted she had "liked it" and asked officers if they "knew what it was like to love something so much that you kill it". hiding his organs Instead of calling the police, or fleeing the scene, Schabusiness continued to perform oral sex on Shad, and use sex toys on his body for several hours. The next morning, she found knives in the house and used them to dismember Shad's body. She said a bread knife was best due to the serrated blade. Schabusiness described how she'd positioned his body on the mattress and beheaded him over the bucket. She poured blood down a shower drain and removed organs. She admitted enjoying beheading Shad, but went on to say she'd "got lazy" as she had intended to take his body parts to her minivan. She was calm as she described the killing. At one point she said, "Damn the head. I can't believe I left the head, though." Then she laughed as she said the police were "going to have fun trying to find all of the organs". Schabusiness would eventually plead not guilty by reason of insanity, but a judge ruled that she was competent to stand trial. At one of her hearings, she attacked her lawyer. At the trial this year, defence lawyers argued that Schabusiness had suffered from years of drug abuse and trauma, including the death of her mother when she was young, and imprisonment of her dad for sexual assault on a minor. They said her mental illness meant she wasn't capable of understanding her actions. But the prosecution told the court about the cold-blooded killing. How she'd sexually abused Shad's corpse then mutilated him. In the lead up to the killing, Schabusiness had researched the Wisconsin serial killer Jeffrey Dahmer and had admitted to a psychologist that she "had a thing" for him. She even had pictures of him on her phone. In July, Schabusiness, now 25, was found guilty of murder, third-degree sexual abuse and mutilating a corpse. Two months later, she was sentenced. A risk to the public Shad's uncle Kelly Thyrion insisted there should be no chance of parole. "I will pray that you meet the same fate as your idealistic Jeffrey Dahmer," he said, referring to his murder by another inmate behind bars. Incredibly, Shad's dad Michael said that Schabusiness should be given a chance. "I forgive you..." he said. "It does no good to hate you." Schabusiness was given life in prison without the chance of parole for the murder and an additional 10 and a half years for mutilation of a corpse and sexual assault. She appeared to smile and pull faces from beneath a large white mask, known as a spit hood to prevent spitting or biting. The judge said Schabusiness was a risk to the public. "This crime offends human decency, it offends human dignity, and it offends the human community." From prison, Schabusiness' husband Warren made a statement saying he was imprisoned because he'd been framed - and added that he'll stand by his wife "forever". Schabusiness is behind bars and Shad's murder has become a series of shocking headlines. A young man lost his life in the most senseless and brutal way, while his killer continues to show no remorse.
Epoch Times
22-04-2025
- Health
- Epoch Times
Common Medications May Disrupt Brain Development
Many people don't think twice when their physician prescribes antidepressants or other medications—after all, mental health is just as important as physical well-being. However, new research suggests that some of these drugs may quietly interfere with brain development in unborn children, raising urgent safety concerns during pregnancy. A February The researchers analyzed how these medications disrupt sterol biosynthesis, particularly affecting the DHCR7 enzyme, which helps regulate cholesterol levels. Their findings highlight potential risks and raise concerns about drug safety, especially during pregnancy and early childhood, when brain cholesterol synthesis is crucial for development. Brain Development Cholesterol is essential for brain development and function. It helps build cell membranes, protects nerve fibers with myelin, and supports connections between neurons. Cholesterol also plays a key role in neuron growth, movement, and communication. Once the blood-brain barrier forms during early development, cholesterol from the body can't enter the brain. As a result, the brain must produce its own cholesterol. The blood-brain barrier is a protective filter that controls what enters the brain from the bloodstream, keeping harmful substances out while allowing essential nutrients in. 'Disrupting cholesterol biosynthesis, particularly during early development, can have profound consequences, including impaired neuronal connectivity, reduced myelination, and altered neurotransmitter function,' said Dustin Hines, a neuroscientist, researcher, and psychology professor at the University of Nevada, Las Vegas, who was not involved in the study, in an email to The Epoch Times. Related Stories 2/17/2024 3/25/2024 'These disruptions may lead to deficits in cognition, sensory processing, and motor coordination,' he said. Cholesterol also plays an important role in making steroid hormones and bile acids essential for various body functions. Maintaining balanced cholesterol levels is important for brain health during development and adulthood. The review highlights findings from previous studies showing that higher brain cholesterol is linked to better memory in aging, while lower levels may increase the risk of depression, as well as aggression, impulsivity, and violence. Moreover, disruptions in cholesterol production or metabolism have been Drug Culprits The review indicates that some widely prescribed medications cross the blood-brain barrier, raising concerns about long-term effects on brain health. Pregnant women and unborn babies are especially at risk because the brain needs cholesterol to develop properly during pregnancy and early childhood. Some of the medications include: Cariprazine—used for mental health conditions Trazodone—antidepressant Aripiprazole—antipsychotic Haloperidol—antipsychotic Sertraline—antidepressant Metoprolol—heart medication Lead study author Dr. Karoly Mirnics, a professor of psychiatry, biochemistry, and molecular biology at the University of Nebraska Medical Center, emphasized how widely these medications are used. 'Approved medications that can interfere with normal sterol biosynthesis during development belong to various classes. These medications are commonly used for cardiology and hypertension treatment, some of which are routinely prescribed to pregnant women,' he told The Epoch Times in an email. Examples of such drugs include statins and ACE inhibitors, which are used to treat high cholesterol and hypertension. Sterols are fat-like molecules essential for making cholesterol in the body. They act as building blocks in the cholesterol production process. Because the brain cannot absorb cholesterol from the blood, it relies on sterol biosynthesis to make its own. 'These medications are generally safe and lifesaving for most people, especially adults. However, during pregnancy, their effects—when combined with certain genetic factors, the use of multiple sterol-inhibiting medications, underlying health conditions, or lifestyle factors—could become harmful to the unborn child,' said Mirnics. The Biochemical Link The medications listed above can block the DHCR7 enzyme, preventing the proper conversion of 7-DHC (7-dehydrocholesterol) into cholesterol. This leads to a buildup of 7-DHC, which is highly reactive and forms harmful byproducts called oxysterols, which can damage neurons, disrupt brain function, and potentially increase the risk of neurodevelopmental disorders. The review suggests that medication-induced sterol disruption may create a biochemical state similar to Smith-Lemli-Opitz syndrome, a genetic condition in which 7-DHC accumulates due to a defective DHCR7 enzyme, leading to developmental and cognitive impairments. Mirnics' previous research supports the current study's findings. His Researchers treated mice with these drugs for 21 days and found that both accumulated in different tissues, altering sterol metabolism. Female mice also showed higher cholesterol clearance in the brain, suggesting their bodies metabolized and removed aripiprazole more quickly than male mice. People at Potential Risk The review also highlights that about 3 percent of the population may be more vulnerable due to genetic differences in sterol processing, and taking multiple medications can further worsen disruption. That means people with one faulty DHCR7 gene are usually healthy and make up about 1 percent to 3 percent of the population. 'However, when exposed to certain medications, their ability to process sterols is significantly impaired, much like a pulled muscle—fine at rest but struggling under stress,' said Mirnics. Another Among these, 43 samples contained medications that block the DHCR7 enzyme, preventing 7-DHC from converting into cholesterol. Moreover, the study notes that taking DHCR7-inhibiting drugs during the first trimester may be harmful to the baby and could increase the risk of birth defects. 'If such medications are essential, it may be beneficial to monitor neurodevelopmental milestones closely, supplement with supportive nutrients, and consider alternative treatments when possible. Parents should also be aware of early warning signs of cognitive or behavioral changes and seek neurodevelopmental assessments if concerns arise,' said Hines. Implications for Patient Care Given cholesterol's essential role in brain development, health care providers should carefully weigh the risks and benefits before prescribing cholesterol-lowering drugs or other sterol-inhibiting medications to pregnant women, infants, and young children. Parents and patients should have open discussions with health care providers about the need for medications that impact cholesterol metabolism. While some medications are necessary during pregnancy, selecting one without DHCR7-inhibiting effects may lower the risk of complications and support better health outcomes for the baby. 'During pregnancy, especially if the unborn child or future mother has a potentially vulnerable genotype, I would suggest replacing the medication with one without the unwanted sterol-inhibiting side effect,' said Mirnics. 'Usually there are plenty of good options, and the majority of medications in all different classes do not interfere with sterol biosynthesis,' he said. While the study suggests that health care providers should assess current and future medications for their potential to affect sterol biosynthesis during development, Mirnics noted the need for larger studies to confirm these findings. 'Animal and cultured cell studies raise concerns, but they are not the same as comprehensive human studies. There is still so much we don't understand, and we should be cautious about drawing premature conclusions,' he said. Patients should not stop taking medications without consulting a doctor. Health care providers should consider the potential effects on sterol biosynthesis when prescribing multiple drugs, including those commonly used to treat heart and psychiatric diseases. If these drugs are necessary, genetic testing for both the mother and unborn child could help assess risks and guide treatment decisions.
Yahoo
28-03-2025
- Yahoo
Charges: Motorist hit woman, 72, at 40 mph as she crossed White Bear Township road
A motorist was nearly two times the legal limit to drive and did not slow down when he hit a 72-year-old woman at 40 mph Thursday afternoon in a White Bear Township crosswalk, according to charges filed Friday. Christopher Ronald Olson, 46, left the scene — telling police that he panicked — but turned himself in to White Bear Lake police about 20 minutes after the incident, which happened around 4:22 p.m. at the intersection of White Bear Parkway and Birch Lake Boulevard at the township's border with White Bear Lake. Olson, of White Bear Lake, is scheduled to go before a Ramsey County judge on Friday on three counts of criminal vehicular homicide — one each for operating a motor vehicle in a negligent manner while intoxicated, having an alcohol concentration 0.08 or more within two hours of driving and causing an accident and then leaving the scene. Olson was convicted of DWI in 2009 and 2012, both out of Ramsey County, court records show. According to the criminal complaint, witnesses told authorities other vehicles had stopped for the woman as she was making her way across White Bear Parkway in a marked crosswalk. She made it halfway across the road when the driver of a Kia Telluride SUV hit her without slowing down or braking, and then fled. The woman flew 30 yards in the air and hit the pavement, rolling several times on her side, witnesses said. She died at the scene. About 20 minutes later, Olson arrived at the White Bear Lake Police Department with his mother and admitted that he had struck a pedestrian. Olson smelled of alcohol and slurred his words. He performed poorly on field-sobriety tests, showing poor balance throughout them. During the one-leg-stand test, he said, 'I'm sorry, I can't do that' and added, 'I've had something to drink, I've admitted it,' the complaint states. Olson registered a 0.14 BAC on a preliminary breath test. The legal limit to drive in Minnesota is 0.08. Later, in an interview with investigators, Olson admitted to drinking four 'shooter' bottles of vodka after work, the complaint says. He said he was driving northbound on White Bear Parkway with his cruise control at 40 mph, which is the posted speed limit in the area. He said he was not paying attention and he hit a person crossing the road. Olson said he left the scene because he panicked and drove to his mother's house. She convinced him to go to the police station. Olson acknowledged that he is prescribed Trazodone, an anti-depressant, and Clonazepam for anxiety. He also admitted to taking 'a gummy or two' before bed. He said he does not combine the medications with alcohol. A judge granted a search warrant to draw Olson's blood for testing. The samples were drawn at about 7:30 p.m., and the analysis is pending. Officers found a loaded handgun in the glove box of Olson's SUV. He does have a permit to carry. At 8:20 p.m., four hours after the crash, he submitted to a second breath test, related to his gun permit. His BAC was 0.08, the complaint says. School bus driver fatally hits man on bike in St. Francis Woman, 72, fatally struck by drunken driver while crossing White Bear Township road, sheriff's office says Turkish student at Tufts University is latest Palestinian supporter swept up in US crackdown 350-pound teacher accused of stepping on sixth-grader's back during lockdown drill in northwestern Minnesota 3rd gunman sentenced in St. Paul murder that led to funeral shooting
