Latest news with #PFS
New York Post
a day ago
- Health
- New York Post
Breakthrough cure for baldness: 100% of male mice regrew fur with new treatment
It's the bald truth. Researchers at San Carlos Clinical Hospital in Madrid have developed a cure for androgenetic alopecia, commonly known as pattern hair loss. An estimated 80 million Americans — 50 million men and 30 million women — experience some form of alopecia, although it affects women differently than men. Advertisement Researchers at San Carlos Clinical Hospital in Madrid have developed a cure for androgenetic alopecia — commonly known as pattern hair loss. Phimchanok – Men usually go through a receding hairline and bald spots, whereas women get thinner at the part line but rarely go fully bald. In the study — published in the journal Stem Cell Research and Therapy — researchers used a combo of fat‑tissue-derived stem cells and the energy molecule ATP to reverse hair loss in mice, with shocking results. Advertisement All of the male mice grew back their coats. Half had full regrowth, while the other half had intensive regrowth. Among females, a whopping 90% saw intense or complete hair revival. Eduardo López Bran, head of the Dermatology Department at the Hospital Clínico San Carlos, explained that their special method 'stimulates hair regeneration by combining the regenerative capacity of the former with the energy provided by the latter. This synergy favors the recovery of the hair follicle, promoting hair growth.' While the findings will need to be replicated in human trials, the results pave a promising way forward in the fight against hair loss. Advertisement All of the male mice grew back their coats. Among females, a whopping 90% saw intense or complete hair revival. Javier – 'In the future, we will be able to offer new solutions that allow us to meet patients' expectations, allowing them access to new treatments that prioritize their well-being,' Eduardo López Bran said. It's an exciting development in an area where there's plenty of room for growth. Advertisement While hair transplant surgery is on the rise, many people don't realize that it actually often takes several procedures to achieve the desired result. 'An alarming trend is patients who now go to perform a hair transplant by a physician who does not consult the patient about his or her hair loss nor is he actively involved in the surgery,' Texas facial plastic surgeon and hair restoration expert Dr. Samuel Lam previously told The Post. He noted that this troubling practice is 'most rampant' in Turkey — where hair transplant surgery has exploded due to its relative affordability — but it is 'also extremely prevalent in the US, unfortunately.' Meanwhile, some men have been vocal about how post-finasteride syndrome (PFS) — a condition in which someone experiences severe side effects after they stop using finasteride — has completely upended their lives. One woman even recently chronicled how PFS destroyed her husband's sex drive — and ended their marriage. Researchers are racing to find new, safer and more affordable hair loss treatments, inventing non-hormonal pills and gummies and repurposing older drugs to find a sustainable solution.
Business Wire
3 days ago
- Business
- Business Wire
Spanish Mountain Gold Concludes Diamond Drill Program with 300 m Step-out Hole Intersecting 0.49 g/t over 100.49 meters in the K-Zone
VANCOUVER, British Columbia--(BUSINESS WIRE)--Spanish Mountain Gold Ltd. (the "Company" or "Spanish Mountain Gold") (TSX-V: SPA) (FSE: S3Y) (OTCQB: SPAUF) is pleased to report final drill results from the recently completed 10,000 m winter drilling program. The results include a strategic step-out hole located approximately 300 m to the northwest of the K-Zone high-grade intercept from hole 25-DH-1286 (refer to press release dated April 24, 2025). Highlights: •Hole 25-DH-1290 intercepted broad mineralization over 100.49 m grading 0.49 g/t Au, from 300 m, including 15.00 m grading 1.29 g/t Au, and 1.00 m grading 12.13 g/t Au, which displayed visible gold. Hole 25-DH-1290 is approximately 300.00 m northwest of hole 25-DH-1286. • Hole 25-DH-1290 also discovered a new cataclastic argillite unit at 240.00 m vertical depth, displaying consistent grades that potentially extend the depth of mineralization in a southwesterly direction, outside the 2021 Prefeasibility Study ('PFS'), open-pit constrained, mineral resource estimate (refer to press release dated May 11, 2021). • Holes 25-DH-1288 and 25-DH-1291 were collared 35.00 m northeast of hole 25-DH-1286 and encountered multiple quartz veins with encouraging gold values. 25-DH-1288 intercepted 46.00 m grading 0.22 g/t Au from 162.00 m, including 8.00 m grading 0.39 g/t Au and 2.00 m grading 1.06 g/t Au. 25-DH-1291 had 5.33 m grading 0.34 g/t Au. Julian Manco, Spanish Mountain Gold's Director of Exploration, commented, 'Overall, we are very pleased with this year's diamond drill campaign, having revealed several significant extensions to gold mineralization at the Phoenix, Outcropping Tuff, and K-Zone targets. These results have grown the mineral endowment potential strike length to 3 km. It is a very exciting time for the project's growth prospects.' The evolving geological and structural interpretation of the Spanish Mountain Gold project area continues to unlock new mineral potential in adjacent structural domains southwest of the 2021 PFS, open pit constrained, mineral resource estimate (refer to press release dated May 11, 2021). Recent drilling results support the hypothesis for a new prospective target area within the mafic tuff unit (Figure 2). Intense hydrothermal alteration was observed within the mafic tuff unit near this fault suggesting possible intrusive characteristics along the south fault that may have also served to transport mineralizing fluids. The gold in soil anomalies observed near the confluence of the major fault structures such as the North Fault, South Fault, Fault 1 and Fault 2 (see Figure 1), continues to demonstrate that these structural intersections represent compelling exploration targets that can be used to explore on a broader project scale. Table 1: 2025 Winter Drill Program – Summarized Gold Assay Results Drillhole ID From To Width(m) Gold Grade (g/t Au) 25-DH-1288 19.00 23.00 4.00 0.23 25-DH-1288 51.00 71.00 20.00 0.24 including 67.92 69.00 1.08 1.25 25-DH-1288 162.00 208.00 46.00 0.22 including 162.00 170.00 8.00 0.39 including 206.00 208.00 2.00 1.06 25-DH-1289 308.00 312.00 4.00 0.33 25-DH-1290 300.00 399.00 100.49 0.49 including 338.00 346.00 8.00 1.84 including 341.00 342.00 1.00 12.13 including 384.00 399.00 15.00 1.29 including 386.00 397.00 11.00 1.62 including 393.00 397.00 4.00 2.56 25-DH-1291 171.67 177.00 5.33 0.34 Expand Notes: Reported intersections are calculated using a 0.15 g/t Au cut-off grade. The complete assay table is available on the Company's website True thickness of mineralization is unknown Table 2: Drill Hole Collar Summary Abbreviations: metres = m, grams per tonne = g/t, gold = Au, visible gold = VG, quality control-quality assurance = QAQC, Prefeasibility Study = PFS, Professional Geologist = Drill Core Processing, Data Verification and Quality Assurance – Quality Control Program (QAQC) Once received from the drill and processed, all drill core samples were sawn in half, labeled, and bagged. The remaining half of the drill core was securely stored on-site. Numbered security tags were applied to sample shipments to ensure chain of custody compliance. The Company inserts quality control (QC) samples at regular intervals, including blanks and reference materials, for all sample shipments to monitor laboratory performance. Standards and blanks account for a minimum of 15% of the samples in addition to the laboratory's internal quality assurance programs. The QAQC program was overseen by the Company's Qualified Person, Julian Manco, Director of Exploration (as described below). Drill core samples were submitted to MSALABS' analytical facility in Prince George, British Columbia, for sample preparation and PhotonAssay TM analysis. The MSALABS facilities are accredited to the International Standards ISO/IEC 17025 and ISO 9001 standard for gold and multi-element assays, with all analytical methods incorporating quality control materials at defined frequencies and established data acceptance criteria. MSALABS Inc. is independent of the Company. PhotonAssay TM The PhotonAssay TM method utilizes gamma ray analysis for gold detection using the Chrysos PhotonAssay TM instrument (PA1408X). This non-destructive, fully automated technique offers high accuracy for analyzing ores and pulps. Sample preparation begins with drying and crushing up to 1 kg of material to achieve at least 70% passing through a 2-millimetre (mm) sieve. The sample is then riffle split to obtain a suitable aliquot for 2 testing cycles (MSALABS Method CPA-Au1). The PhotonAssay TM instrument bombards 400 - 600 gram samples contained in sealed containers with gamma rays. These containers remain sealed throughout the process, preserving the sample for potential further testing. The analysis is performed robotically, with results that integrate into existing laboratory management systems. Each sample is accompanied by a reference disc traceable to a Certified Reference Material (CRM). Both the sample and reference disc undergo gamma ray exposure, with signals detected and analyzed to ensure accurate and reliable results. The method offers a gold detection range from 0.015 parts per million (ppm - lower limit) to 10,000 ppm (upper limit). Quality control includes the use of reference materials and blanks, with all results reviewed by a competent person before reporting. Spanish Mountain Gold implemented two QAQC methodologies to validate the accuracy of PhotonAssay TM results, both demonstrating good comparability: 1) comparative analysis of diverse mineralization styles using Total Au screen metallic methods with both FAS-415 (gravimetric finish) and FAS-211 (AAS finish), and 2) comprehensive testing of both sample aliquots and rejects using FAS-211 (AAS finish). QAQC Testing typically can include the following spot checks: 1) Pulverizing tests to evaluate variability in sample preparation, 2) Cross-analysis at external laboratories using screen metallic method, and 3) Four-cycle radiation testing to identify and calibrate potential variability in gold results with variable radiation intensity. To effectively manage the nugget effect gold samples MSALABS tested samples to "extinction" (CPA-Au1E method). This approach divides samples into multiple splits, analyzes each separately using PhotonAssay TM, and then calculates a weighted average of the results. By testing various portions of the sample independently and combining their values proportionally, this method provides significantly more representative gold values than traditional single-split analysis for samples with a large nugget effect. Multi-Elemental Analysis For the 2025 drilling campaign Spanish Mountain Gold used IMS-230 method to provide multi-element determination using a four-acid digestion followed by ICP-OES and ICP-MS analysis. Key Process Steps: Sample Preparation: Samples are dried and ground to specific criteria (85% passing 75 microns (μm) for rocks and drill core; 180μm for soils and sediments). A homogeneous 10-gram sample is required. Digestion: Samples undergo sequential digestion with nitric, perchloric, hydrofluoric, and hydrochloric acids, followed by dilution with deionized water. Analysis: The solution is analyzed via ICP-OES and ICP-MS for multi-element quantification. Quality Control: The process includes reference materials, blanks, and duplicates, with corrections for spectral interferences and thorough review before final reporting. Julian Manco, has verified the data disclosed in this news release. The data verification process involved a multi-step approach to ensure accuracy and integrity. This included a detailed quality control (QC) analysis of the data, which was performed using both internal and external platforms, such as the MxDeposit™ software. These QC checks involved the analysis of certified reference materials (CRMs), blanks, and duplicates to confirm the reliability of the assay results. In addition, Mr. Manco, conducted a field inspection of the specific drill intervals mentioned in this release to directly observe the geological features and verified the nature of the results presented. Qualified Person Julian Manco, Director of Exploration with Spanish Mountain Gold, is the Qualified Person as defined under National Instrument 43-101 who has reviewed and has approved the contents of this news release. About Spanish Mountain Gold Ltd. Spanish Mountain Gold Ltd. is focused on advancing its 100%-owned Spanish Mountain Gold Project (Project) towards construction of the next gold mine in the Cariboo Gold Corridor, British Columbia. The Company expects to release at the end of Q2, 2025, the results for the Project's newly de-risked and optimized Preliminary Economic Assessment (PEA) with an updated Mineral Resource Estimate (MRE). Upon receipt of the new PEA and updated MRE, the company will decide the next steps to advance the Project to position the company to make a construction decision in or before 2027. We are striving to be a leader in community and Indigenous relations by leveraging technology and innovation to build the 'greenest' gold mine in Canada. The Relentless Pursuit for Better Gold means seeking new ways to achieve optimal financial outcomes that are safer, minimize environmental impact and create meaningful sustainability for communities. Details of the Company are available on and on the Company's website: On Behalf of the Board, 'Peter Mah' President, Chief Executive Officer and Director Spanish Mountain Gold Ltd. Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release. FORWARD-LOOKING INFORMATION: Certain of the statements and information in this press release constitute "forward-looking information". Any statements or information that express or involve discussions with respect to predictions, expectations, beliefs, plans, projections, objectives, assumptions or future events or performance (often, but not always, using words or phrases such as "expects", "anticipates", "believes", "plans", "estimates", "intends", "targets", "goals", "forecasts", "objectives", "potential" or variations thereof or stating that certain actions, events or results "may", "could", "would", "might" or "will" be taken, occur or be achieved, or the negative of any of these terms and similar expressions) are not statements of historical fact and may be considered forward-looking information. The Company's forward-looking information is based on the assumptions, beliefs, expectations and opinions of management as of the date of this press release and include but are not limited to information with respect to, the potential to extend mineralization within the near-surface environment; the potential to expand resources and to find higher-grade mineralization at depth; the timing, size and budget of a winter drill program, and the results thereof; and the delivery of a maiden resource for the Phoenix Target, and the timing and results thereof. Other than as required by applicable securities laws, the Company does not assume any obligation to update forward-looking information if circumstances or management's assumptions, beliefs, expectations or opinions should change, or changes in any other events affecting such statements or information. For the reasons set forth above, investors should not place undue reliance on forward-looking information.
Business Insider
7 days ago
- Business
- Business Insider
Provident Financial exec chairman Martin sells 55,668 common shares
In a regulatory filing, Provident Financial (PFS) executive chairman Christopher Martin disclosed the sale of 55,668 common shares of the company on June 11 at a price of $17.065 per share. Confident Investing Starts Here: Easily unpack a company's performance with TipRanks' new KPI Data for smart investment decisions Receive undervalued, market resilient stocks right to your inbox with TipRanks' Smart Value Newsletter Published first on TheFly – the ultimate source for real-time, market-moving breaking financial news. Try Now>>
Yahoo
10-06-2025
- Business
- Yahoo
EDM Resources secures $58m gypsum offtake deal
Canadian exploration and mining company EDM Resources has signed a definitive gypsum offtake supply agreement valued at $58m (C$79.39m) with a Canadian gypsum producer and wallboard manufacturer for gypsum produced from the Scotia Mine in Nova Scotia, Canada. The agreement, signed on 3 June 2025, will see the gypsum offtaker make an advance payment of $250,000 for a five-year exclusivity on gypsum produced at the Scotia Mine. This payment is unsecured and non-refundable if production does not commence before 31 December 2026. The offtake represents half of the total mineral reserve and is based on projected volumes over a ten-year period. The Scotia Mine has a defined NI 43-101 mineral reserve of 5.1 million tonnes (mt) of gypsum, comprising 1,530,000 tonnes (t) of proven mineral reserves with a gypsum grade of 92.8%. The probable mineral reserves are estimated at 3.65mt with a grade of 91.4%, as per the 2021 pre-feasibility study (PFS). The PFS indicated an expected gypsum revenue of $43.9m based on 2021 prices of $8.6/t. Gypsum is widely used in the construction and agricultural industries, among others. The average price for crude gypsum was $13/t in 2024, with an expected increase due to rising demand in North America. The gypsum offtaker will pay for gypsum delivered free-on-board trucks at the Scotia Mine on a take-or-pay contract basis. EDM Resources president and CEO Mark Haywood said: 'We are very pleased to secure the third revenue stream opportunity for our Scotia Mine, which is in addition to the forecast zinc and lead revenue streams. 'With the execution of the new gypsum offtake agreement, the Scotia Mine secures market rate payments for at least 2.5mt of gypsum.' EDM Resources is currently in the exploration and evaluation stage and has not generated revenue from operations. The company's ability to execute its objectives depends on its capacity to secure additional financing. Proceeds from the sale of gypsum under the offtake agreement are contingent upon the commencement of production at the Scotia Mine, with various risks and uncertainties. "EDM Resources secures $58m gypsum offtake deal" was originally created and published by Mining Technology, a GlobalData owned brand. The information on this site has been included in good faith for general informational purposes only. It is not intended to amount to advice on which you should rely, and we give no representation, warranty or guarantee, whether express or implied as to its accuracy or completeness. You must obtain professional or specialist advice before taking, or refraining from, any action on the basis of the content on our site. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
10-06-2025
- Business
- Yahoo
GXO Introduces Enhanced GXO Direct Solution in the U.S.
GXO Introduces Enhanced GXO Direct Solution in the U.S. Service platform from PFS acquisition integrated into a unified, scalable fulfillment offering for midsize companies & growing brands GREENWICH, Conn. , June 10, 2025 (GLOBE NEWSWIRE) -- GXO Logistics, Inc. (NYSE: GXO), the world's largest pure-play contract logistics provider, announced today the launch of an enhanced offering for growing midsize companies in the United States by unifying the premier services platform it acquired through its acquisition of PFSweb (PFS) with GXO Direct, its industry-leading multi-tenant warehousing solution. 'We are excited to expand our offering for growing midsize companies by bringing together the capabilities of GXO Direct and PFS with our extensive cross-vertical expertise,' said Jorge Guanter, President of Americas and Asia Pacific for GXO. 'One of the biggest challenges businesses face as they grow is finding a partner that can address their needs across the entire logistics value chain. With our expertise, scale and breadth of services, we believe there is meaningful opportunity to be the go-to, long-term partner for high growth, mid-size brands today and their dedicated, enterprise solutions provider as they scale and grow.' With fast onboarding, flexible space, cutting edge technology and a nationwide network of strategically located fulfillment centers, GXO Direct has been a go-to, cost-effective solution for omnichannel retail and ecommerce customers for several years. Now, GXO is integrating the key service capabilities it gained from its acquisition of PFS, including high touch contact center services, secure payments and fraud protection and distributed order orchestration systems, into a new unified solution. The enhanced GXO Direct U.S. product offers: Direct to consumer fulfillment: Custom scalable order fulfillment for all online channels and ecommerce marketplaces; Multi-tenant warehousing: A nationwide network of multi-tenant sites that offer shared infrastructure, overhead, equipment and workforce solutions; Business-to-business and retail: Solutions engineered specifically for the evolving challenges of B2B retail operations; Short-term storage & distribution: Immediate access to premium space for pop-up fulfillment, overflow storage or one-time projects; Value-added services: Personalized experiences that inspire brand loyalty, including personalization, gift box and gift wrapping, kitting and more; Transportation: A range of transport solutions, including negotiated parcel rates, dedicated fleet and freight brokerage, that leverage GXO's scale to reduce costs and enhance service levels; and Commerce Services: Complementary services native to the PFS platform, including contact center services, order management, fraud & chargeback dispute services. Zach Thomann, COO of GXO in the Americas and Asia Pacific, and Jamie Saucedo, SVP of Operations, both industry veterans from PFS, lead GXO Direct in the U.S. 'Growing brands today are looking for a cost effective, quick solution to supplement their fulfillment offering with a global provider that can bring innovation and agility to accelerate their growth trajectory, and we are uniquely positioned to deliver in an outsized way. With our enhanced GXO Direct product, we can enable one day delivery for brands anywhere nationwide, that offers fast start-up, lower fixed costs, flexible contract terms and an array of value-added services,' added Thomann. About GXO GXO Logistics, Inc. (NYSE: GXO) is the world's largest pure-play contract logistics provider and is benefiting from the rapid growth of ecommerce, automation and outsourcing. GXO is committed to providing an inclusive, world-class workplace for more than 150,000 team members across more than 1,000 facilities totaling approximately 200 million square feet. The company partners with the world's leading blue-chip companies to solve complex logistics challenges with technologically advanced supply chain and ecommerce solutions, at scale and with speed. GXO corporate headquarters is in Greenwich, Connecticut, USA. Visit for more information and connect with GXO on LinkedIn, X, Facebook, Instagram and YouTube. Media contacts Matthew Schmidt +1 203-307-2809 Kathleen Juviler+1 203-291-9121 Attachment GXO Introduces Enhanced GXO Direct Solution in the in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
