Latest news with #PES
Yahoo
12-06-2025
- Entertainment
- Yahoo
WTF: this channel swaps the highlights for PES footage 😭
How did no one notice? Has it ever happened to you that you wanted to watch a match summary on YouTube, only to stumble upon a video from some clever guy who's streaming FC 25 or PES gameplay instead? Well, you're not the only one it happens to. Advertisement Let's head to Serbia, where the national team hosted Andorra as part of the Nations League. After the Serbs' victory (3-0), the TV channel Happy wanted to show their viewers a summary of the White Eagles' win. But instead, what they got... were images from PES. A totally surreal scene that sparked laughter among many internet users. The only question now is whether it was a deliberate choice, or if the person in charge of the segment was fooled by the game footage. We can't wait to see FC 25 on the 8pm news. Also read: - De Bruyne has made his choice, his new club is known! (Official) - Ballon d'Or - The date for the nominees announcement is set! Advertisement - A top Italian coach arrives to train Ronaldo with a XXL paycheck This article was translated into English by Artificial Intelligence. You can read the original version in 🇫🇷 here. 📸 ADNAN BECI - AFP or licensors
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First Post
11-06-2025
- Business
- First Post
China is obessesing over Pakistan's donkeys. Here's how it is hurting the poor
Over the past three years, Pakistan has seen a steady rise in its donkey population, thanks to growing demand from its all-weather ally, China. The hides of the animals are used in the production of ejiao, a gelatin used in traditional Chinese medicine, But it is draining poor Pakistani of their livelihood read more Officials have shared that there are plans to export over 200,000 donkeys annually, and farms are now rearing special breeds, including American meant, for this meet China's demand. File image/Reuters The China–Pakistan friendship is often described as 'higher than mountains, deeper than the ocean, stronger than steel and sweeter than honey'. Now, even Pakistani donkeys seem to be playing a role in strengthening this bond. Over the past three years, Pakistan has seen a steady rise in its donkey population, thanks to growing demand from its all-weather ally, China. The humble farm animal is now turning into a valuable export for the cash-strapped nation. STORY CONTINUES BELOW THIS AD But as the demand rises, the profits aren't reaching everyone. Many local owners, who depend on the animal for their daily bread, are now finding it even harder to afford or replace them. For many, it's becoming a struggle to survive. So, what exactly is driving China's interest in Pakistani donkeys? And how is this booming trade creating problems for local communities? Here's a look at everything that's going on. The donkey boom in Pakistan Over the past five years, Pakistan's donkey population has seen a noticeable rise, and it continues to grow steadily. As per the Pakistan Economic Survey (PES) for 2023–24, the number of donkeys in the country has now crossed 6 million, up from 5.9 million the previous year. Earlier figures show a gradual climb — 5.5 million in 2019–2020, and 5.6 million in 2020–2021. Donkeys are, in fact, among the few animals in Pakistan whose numbers are on the rise. In contrast, populations of horses and mules have remained unchanged over the past five years, stuck at 0.4 million and 0.2 million, respectively. One key reason behind this growth is the rising demand from China and Pakistan's readiness to tap into this opportunity. To cater to this demand, dedicated donkey farms and slaughterhouses have been set up in areas such as Okara and Gwadar. In Gwadar, a $7 million facility was opened earlier this year specifically to process donkeys for export, mainly to China. STORY CONTINUES BELOW THIS AD Officials have shared that there are plans to export over 200,000 donkeys annually, and farms are now rearing special breeds, including American meant, for this growing market. Muhammad Hanif, 50, a labourer bathes his However, China earlier used to import its stock of donkeys from Niger and Burkina Faso, until the two West African countries banned their export. Since then, the country has become dependent on Pakistan for its supply. Dr Guo Jing Feng, who operates a medical centre in Karachi, highlighted that China's need for donkey hides is expected to rise further. 'This is now a global trade,' he was quoted as saying in a PTI report. 'And China's demand is much higher than its supply.' The Economic Survey also emphasised the government's focus on livestock as an economic driver. 'By implementing these measures, the government aims to stimulate growth in the livestock sector, generate employment opportunities, and contribute to the country's overall economic growth and food security,' the report stated. STORY CONTINUES BELOW THIS AD But why does China want Pakistan's donkeys? China is importing donkeys from Pakistan mainly to meet the rising demand for ejiao, a traditional medicine that's been used for over 3,000 years. Ejiao is made by boiling gelatin from donkey hides and mixing it with herbs and other ingredients. According to a 2019 report by The Guardian, it's believed to help with immunity, bleeding issues, sleep quality, and overall energy levels. To keep the ejiao industry running, an estimated 5.9 million donkey skins are needed — a demand that China's own shrinking donkey population can no longer meet. Pakistan, which has one of the largest donkey populations in the world, only behind Ethiopia and Sudan, has become a key supplier for China. Donkey traders say that Chinese buyers are so eager for hides that they're even purchasing weak or sick animals. In one such case, as reported by PTI, a group of buyers paid Rs 40,000 each for 14 unhealthy donkeys — just for their skins. STORY CONTINUES BELOW THIS AD China is importing donkeys from Pakistan mainly to meet the rising demand for ejiao, a traditional medicine made from donkey hides and has been in use for over 3,000 years. File image/ Reuters But it's not just the hides that interest China. In Hebei province, donkey meat is considered a delicacy. Dishes like donkey meat burgers, or lǘròu huǒshāo in Chinese, are popular street foods, especially in cities like Baoding and Hejian. On paper, a flourishing donkey trade looks like a win-win situation for cash-strapped Pakistan. But in reality, the boom in exports is having a painful impact back home. How China's craze for donkeys is crushing Pakistan's poor While the export of donkeys might seem like a good economic opportunity, it's creating serious problems for people in Pakistan who rely on these animals for their daily livelihood. In rural and low-income areas across the country, donkeys play a crucial role. They carry water, transport bricks, pull carts, and do other hard labour that machinery often can't manage. While the export of donkeys might seem like a good economic opportunity, it's creating serious problems for people in Pakistan who rely on these animals for their daily livelihood. File image/ Reuters A 2019 study by equine charity Brooke estimated that a single donkey transports up to 1,000 kilograms of non-recyclable waste and 100 kilograms of recyclable waste every day. Dr Sher Nawaz, regional manager of Brooke Pakistan (Sindh), told The Dawn that each donkey supports around six people, helping them earn between Rs 1,000 and Rs 1,500 a day. STORY CONTINUES BELOW THIS AD But with China's demand rising, so are prices, pushing donkeys out of reach for many workers who desperately need them. Just last week, Abdul Rasheed found himself in crisis after his donkey, Tiger — his only means of income — died in an accident. Now, without a cart, he has no way to earn a living. But buying a new donkey is simply too expensive. Prices have soared to Rs 2 lakh in cities like Karachi, far more than the Rs 30,000 Rasheed paid for Tiger eight years ago. Even at Lyari, Pakistan's biggest donkey market, the cost of a healthy donkey has skyrocketed. Rasheed says the cheapest one he could find was Rs 1.55 lakh. 'How can I afford that? Even if I somehow buy one, what if it dies before I recover my investment?' he asked. But with China's demand rising, so are prices, pushing donkeys out of reach for many workers who desperately need them. File image/ Reuters And Rasheed isn't alone. Across the country, many others who rely on donkeys for their day-to-day earnings are struggling with the same problem. STORY CONTINUES BELOW THIS AD Beyond the economic pressure, the growing export trade is also raising ethical and religious concerns. Saleem Reza, a senior official of the Karachi Chamber of Commerce and Industry, pointed out a key issue. 'The government has to ensure even if donkeys are in demand by China, they must be sent there without being slaughtered in Pakistan,' he told PTI. 'Donkey meat is haram for us, and there has to be a process to ensure it is not used commercially, unethically, or illegally. There is a need to establish designated factories for the slaughtering and processing of hides and meat to ensure it does not circulate in Pakistani markets,' he added. As the trade grows, so do the questions. For people like Rasheed, it's not just about donkeys. It's about dignity, survival, and the quiet struggle to keep moving forward. With input from agencies
Yahoo
20-05-2025
- Health
- Yahoo
Soleno Therapeutics Announces Data Presentation Showing that Resumption of Treatment with VYKAT(TM) XR after a Randomized Withdrawal Period was Associated with Significant Improvements in Hyperphagia and Behavioral Symptoms in Participants with Prader-Willi Syndrome
REDWOOD CITY, Calif., May 20, 2025 (GLOBE NEWSWIRE) -- Soleno Therapeutics, Inc. (NASDAQ: SLNO), a biopharmaceutical company developing novel therapeutics for the treatment of rare diseases, today announced data presented from its clinical development program of VYKAT™ XR (diazoxide choline) extended-release tablets, previously referred to as DCCR, at the Pediatric Endocrine Society (PES) Annual Meeting 2025, which was held May 15-18 in National Harbor, Maryland, USA. The presentation showed that resumption of VYKAT XR treatment in participants with PWS following a 16-week randomized withdrawal was associated with significant improvements in both hyperphagia and behavioral symptoms. 'We are pleased to share the results from our ongoing clinical development program for VYKAT XR,' said Anish Bhatnagar, M.D., Chairman and Chief Executive Officer of Soleno Therapeutics. 'These results support the effectiveness of VYKAT XR in managing the critical symptoms of PWS and highlight the importance of long-term, continuous treatment.' Data Presented at the 2025 Pediatric Endocrine Society (PES) Annual Meeting Following long-term open label treatment with VYKAT XR for approximately 3 years (C602-OLE) and 16 weeks of randomized withdrawal (C602-RWP), participants who were randomized to placebo and restarted VYKAT XR in the open-label Study C614 showed improvements in hyperphagia by 13 weeks, with continued benefit through one year. Specifically, these participants showed a 6.3-point reduction in the Hyperphagia Questionnaire for Clinical Trials (HQ-CT) total score at one year —returning to levels similar to their pre-withdrawal baseline. Behavioral improvements were also demonstrated through one year, with improvements across all six domains assessed. About PWSThe Prader-Willi Syndrome Association USA estimates that PWS occurs in one in every 15,000 live births. The hallmark symptom of this disorder is hyperphagia, a chronic and life-threatening condition characterized by feelings of intense, persistent hunger, food pre-occupation, and an extreme drive to seek and consume food, which can severely diminish the quality of life for individuals with PWS and their families. Additional characteristics of PWS include behavioral problems, cognitive disabilities, low muscle tone, short stature (when not treated with growth hormone), the accumulation of excess body fat, developmental delays, and incomplete sexual development. Hyperphagia can lead to significant mortality (e.g., stomach rupture, choking, accidental death due to food seeking behavior) and longer term, co-morbidities such as diabetes, obesity, and cardiovascular disease. About VYKAT XR VYKAT XR was approved by the U.S. Food and Drug Administration (FDA) on March 26, 2025, and is now commercially available to U.S. patients. VYKAT XR is indicated for the treatment of hyperphagia in adults and pediatric patients 4 years of age and older with Prader-Willi syndrome (PWS). IMPORTANT SAFETY INFORMATION ContraindicationsUse of VYKAT XR is contraindicated in patients who have a known hypersensitivity to diazoxide, other components of VYKAT XR, or to thiazides. Warnings and Precautions HyperglycemiaHyperglycemia, including diabetic ketoacidosis, has been reported. Before initiating VYKAT XR, test fasting plasma glucose (FPG) and HbA1c; optimize blood glucose in patients who have hyperglycemia. During treatment, regularly monitor fasting glucose (FPG or fasting blood glucose) and HbA1c. Monitor fasting glucose more frequently during the first few weeks of treatment in patients with risk factors for hyperglycemia. Risk of Fluid OverloadEdema, including severe reactions associated with fluid overload, has been reported. Monitor for signs or symptoms of edema or fluid overload. VYKAT XR has not been studied in patients with compromised cardiac reserve and should be used with caution in these patients. Adverse ReactionsThe most common adverse reactions (incidence ≥10% and at least 2% greater than placebo) included hypertrichosis, edema, hyperglycemia, and rash. Please see the full Prescribing Information, including Medication Guide. About Soleno Therapeutics, is focused on the development and commercialization of novel therapeutics for the treatment of rare diseases. The company's first commercial product, VYKAT XR (diazoxide choline) extended-release tablets, formerly known as DCCR, is a once-daily oral treatment for hyperphagia in adults and children 4 years of age and older with Prader-Willi syndrome. For more information, please visit Forward-Looking StatementsThis press release contains forward-looking statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended. All statements other than statements of historical facts contained in this press release are forward-looking statements. In some cases, you can identify forward-looking statements by terms such as "may," "will," "should," "expect," "plan," "anticipate," "could," "intend," "target," "project," "contemplates," "believes," "estimates," "predicts," "potential" or "continue" or the negative of these terms or other similar expressions. These forward-looking statements speak only as of the date of this press release and are subject to a number of risks, uncertainties and assumptions, including those described in the company's prior press releases and in the periodic reports it files with the SEC. The events and circumstances reflected in the company's forward-looking statements may not be achieved or occur and actual results could differ materially from those projected in the forward-looking statements. Except as required by applicable law, the company does not plan to publicly update or revise any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances or otherwise. Corporate Contact:Brian RitchieLifeSci Advisors, LLC212-915-2578 Media Contact:Soleno Therapeuticsmedia@ #2Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Time of India
10-05-2025
- General
- Time of India
Meghalaya embraces Miyawaki method for promoting afforestation
1 2 Shillong: Meghalaya is taking a step forward in protecting the environment by using the Miyawaki Forest method — a fast and effective way of growing dense, native forests .This method was developed in Japan by botanist Akira Miyawaki and is now being used across the state as part of an afforestation project led by the state soil and water conservation Conrad K Sangma played a key role in pushing for environmental conservation and raised serious concerns about deforestation across the state and has been working to restore green cover through various programmes."To support this effort, the state has initiated different interventions including 'Green Meghalaya' and has partnered with different organisations to promote conservation and afforestation programme. The state govt is also providing financial incentives through the Payment for Ecosystem Services (PES) for conservation of forest cover," an official statement Thursday, the CM visited a Miyawaki forest site at Mawsharoh, Ummir, in East Khasi Hills district, where the method is being used to grow a forest on a 1.5-hectare area. Operation Sindoor Pak drones enter Indian airspace, explosions heard just hours after truce deal Sirens, explosions in border districts after Pak breaks deal: What we know so far 'What happened to ceasefire?' J&K CM after explosions heard across Srinagar Currently, similar projects are being implemented on a total of 25,000 hectares throughout from the soil and water conservation department shared how the Miyawaki method is helping to restore the ecosystem. "The method involves planting native trees close together in layers, which leads to rapid growth of dense, self-sustaining forests. These forests grow faster than traditional plantations and require less maintenance over time," the official statement project is being carried out with strong support from local communities, who are actively involved in the planting and caring of these forests. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Click Here - This Might Save You From Losing Money Expertinspector Click Here Undo The first Miyawaki forest plantation in Meghalaya began three years ago in Garo Hills as a pilot project."The project will be expanded across the state as one of our main afforestation drives," the CM said."The Miyawaki method not only helps restore greenery but also brings many other benefits. These mini-forests help absorb carbon dioxide, fight climate change, improve air quality, reduce noise pollution, and provide shelter for wildlife. Meghalaya's rich soil and unique climate make it ideal for growing these forests," the official statement said.
New Indian Express
05-05-2025
- Politics
- New Indian Express
Why the Census isn't an answer to all questions
The Union government has announced that caste enumeration would be a part of the next nationwide census. Population enumeration by castes has not been published after 1931. The reason being that caste was a colonial invention that tried to replace varna and jati, and later amended with ethnographic surveys, occupation and social hierarchies. This attempt made caste a fluid identity, making it inconvenient to fit into the diverse social systems in India. However, caste debates based on the censuses from 1881 to 1931 continue till today. A list of castes can be enforced by law, while social identities continue to be more varied—the consequent problems should be tackled. Another real problem may crop up about estimating the socio-economic characteristics of each caste to design reservation policies and deliver welfare schemes. This can be captured only when a full-fledged census that includes a large number of socio-economic variables and caste information is conducted under the purview of the Census Act. Even after enumeration, a better validation of the census data is always required, as it is also prone to errors. It is to be noted that the net omission rate, measured as the ratio of the number of omitted persons per 1,000 persons enumerated in the census after adjusting for duplication, was nearly 20 percent on average in the last four decennial exercises. A general practice of a census operation is that it is followed by a Post-Enumeration Survey (PES), which involves carrying out an independent survey for a sample of the population to ascertain the accuracy of the information. The PES helps in identifying under-enumeration or over-enumeration across coverage areas. India has conducted a PES after every decennial census, but has not published the data gathered or the error corrections. This only increases our apprehension about the quality of enumeration and estimation from the census.
