Latest news with #MerckKGaA
Globe and Mail
2 days ago
- Business
- Globe and Mail
Peptide Synthesis Market to Hit USD 1.41 Billion by 2029 with 11.7% CAGR
"Thermo Fisher Scientific Inc. is one of the dominant players in the peptide synthesis market. The company's leading position is attributable to its diversified product portfolio, strong geographic presence, and adoption of various growth strategies." The market for peptide synthesis market is competitive, with key players strategizing to capture the majority market share. Prominent players in the peptide synthesis market are Thermo Fisher Scientific, Inc. (US), Merck KGaA (Germany), Agilent Technologies Inc. (US), Kaneka Corporation (Japan), GenScript (China) The Peptide Synthesis market valued at US$ 0.78 Billion in 2023, is forecasted to grow at a robust CAGR of 11.7%, reaching US$ 0.81 Billion in 2024 and an impressive US$ 1.41 Billion by 2029. The peptide synthesis market is driven by the growing demand for therapeutic peptides in treating chronic diseases, including cancer, diabetes, and cardiovascular disorders. Advancements in solid-phase peptide synthesis (SPPS) and hybrid approaches have significantly improved efficiency, yield, and cost-effectiveness, fueling adoption in pharmaceutical R&D. The rise of personalized medicine has further expanded the need for custom peptide synthesis, supporting applications in targeted therapies and biomarker research. Emerging trends such as the integration of automation and AI-driven platforms among the instruments is further likely to fuel the market growth in coming years. Browse in-depth TOC on " Peptide Synthesis Market" 513 - Tables 55 - Figures 460 - Pages Based on offerings, the market is segmented into products and services. By-products market is further divided into consumables and instruments. Among these consumables dominated the peptide synthesis market. The consumables segment is further bifurcated into reagents and other consumables. The reagents market is further divided into resins, amino acids, coupling reagents, dyes & fluorescent labeling reagents, deprotection agents, cleavage reagents, and other reagents. In 2023, the resins segment accounted for the largest share of the peptide synthesis market. Resins play an important role in solid-phase peptide synthesis (SPPS), the most widely used method for peptide production. For instance, polystyrene-based and PEG-based resins are extensively used due to their high stability and scalability. The instruments segment is further divided into peptide synthesizers, chromatography equipment, lyophilizers, and others. The peptide synthesizer segment is further divided into automated and manual peptide synthesizers. Peptide synthesizers dominated the instruments market due to their ability to automate and streamline peptide production, making them essential for research and industrial applications. The growing demand for custom peptides in drug discovery, diagnostic research, and therapeutic applications has further boosted the adoption of advanced synthesizers. The services segment is further divided into peptide library synthesis, peptide synthesis, peptide purification services, and peptide analysis services. The peptide synthesis segment dominated the services segment. The increasing adoption of peptides in emerging fields such as personalized medicine, vaccine development, and epigenetics drives demand for custom synthesis solutions, fostering growth in the segment. Based on technique, the peptide synthesis market is segmented into chemical and biological. The chemical segment is further divided into solid-phase peptide synthesis, solution-phase peptide synthesis, and others. The biological segment is divided into recombinant DNA technology and enzymes. The chemical segment dominated the market in 2023. The solid-phase peptide synthesis (SPPS) segment dominates the peptide synthesis market due to its efficiency, scalability, and widespread adoption in research and commercial applications. The dominance of SPPS is further driven by advancements in automation and reagent technologies, which have significantly reduced synthesis time and enhanced yield. Based on application, the market is divided into therapeutics, diagnostics, and research & development. Therapeutics by indication is further divided into cancer, diabetes, obesity, autoimmune disease, and other disease indications. Therapeutics by molecules is further segmented into peptide-based vaccines, peptide-drug conjugates (PDCs), peptide inhibitors, and other molecules. Therapeutic applications dominated the peptide synthesis market due to the growing demand for peptide-based drugs, which offer targeted and effective treatments with fewer side effects compared to traditional small molecules. The peptide synthesis market is segmented by end users into pharmaceutical and biotechnology companies, CDMOS & CROS, academic and research institutes, medical device companies, and hospitals and diagnostic centers. The pharmaceutical and biotechnology companies segment held the largest market share in 2023. The rise of peptide-based drugs and biologics has led to increased investments by pharmaceutical and biotech firms in peptide synthesis technologies, particularly in the production of therapeutic peptides for diseases such as cancer, diabetes, and autoimmune disorders. These factors are fueling the growth of the segment. The market is segmented by region into North America, Europe, Asia Pacific, Latin America, Middle East and Africa. North America dominated the peptide synthesis market in 2023, and the Asia Pacific region is likely to grow at a significant CAGR during the forecast period. US-dominated North American peptide synthesis market owing to the presence of strong pharmaceutical and biotechnology companies in the country, advanced research infrastructure, and significant investments in drug discovery and development. The Asia Pacific region is anticipated to grow at a significant CAGR due to growing focus on personalized medicine and peptide-based therapeutics in the region fuels the demand for advanced peptide synthesis technologies. The market for peptide synthesis market is competitive, with key players strategizing to capture the majority market share. Prominent players in the peptide synthesis market are Thermo Fisher Scientific, Inc. (US), Merck KGaA (Germany), Agilent Technologies Inc. (US), Kaneka Corporation (Japan), GenScript (China), and Bachem Holding AG (Switzerland), among others. The market players have adopted various organic and inorganic growth strategies, such as the development of advanced products, partnerships, agreements, expansions, and acquisitions to strengthen their position in the peptide synthesis market. Thermo Fisher Scientific Inc. is one of the dominant players in the peptide synthesis market. The company's leading position is attributable to its diversified product portfolio, strong geographic presence, and adoption of various growth strategies. The company offers a wide range of peptide synthesis products and services. The company has adopted different growth strategies, such as deals that include agreements, and acquisitions, to maintain its leading position in the peptide synthesis market. The company's strong customer support and extensive distribution network further solidify the company's leadership position in the market. Merck KGaA is a key player in the peptide synthesis market, leveraging its expertise in life sciences and advanced chemical technologies. The company's Novabiochem product line offers a broad range of high-quality reagents, resins, and building blocks essential for efficient and reliable peptide synthesis. Merck KGaA focuses on innovation supporting advanced techniques such as microwave-assisted synthesis, which significantly improves reaction efficiency and yield. The company's strategic partnerships and increased investments in biopharmaceutical R&D further enhance its competitive edge in the market. Merck's strong geographic presence and adoption of growth strategies further contribute to its dominance in the market. For more information, Inquire Now!
Business Wire
2 days ago
- Business
- Business Wire
MilliporeSigma Announces Neoclease as Winner of 2025 North American Advance Biotech Grant
BURLINGTON, Mass.--(BUSINESS WIRE)--MilliporeSigma, the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced Neoclease as the winner of the 2025 North American Advance Biotech Grant. The Boston-based biotech startup develops AI-designed gene editing therapies for Parkinson's disease. 'We're committed to empowering biotech innovators who are advancing transformative modalities like gene editing,' said Sebastián Arana, Head of Process Solutions, Life Science business of Merck KGaA, Darmstadt, Germany. 'By combining Neoclease's AI-designed gene-editing platform with our technologies, regulatory expertise, and process support, we aim to help accelerate new treatments that minimize side effects and maximize effectiveness for patients.' Neoclease's platform combines generative AI and synthetic biology to develop next-generation, precision gene-editing therapies. Neoclease's lead candidate, NCX-L2, is designed to slow or halt the progression of Parkinson's disease – a condition that currently has no disease-modifying treatments. More broadly, Neoclease's approach has the potential to address more than 6,000 monogenic diseases by targeting the root causes of illness rather than only managing symptoms. As part of the grant, Neoclease will receive access to MilliporeSigma's products, technologies, and contract testing services, as well as expert consultation and training through the M Lab™ Collaboration Center and Emprove ® program. M Lab™ Collaboration Centers offer hands-on technical solutions and process optimization, while the Emprove ® Program simplifies risk management and regulatory compliance through quality products, detailed documentation, and dedicated support. These resources will support Neoclease in scaling its processes, optimizing manufacturing, and navigating regulatory requirements. The Advance Biotech Grant Program, launched in 2014, reflects the ongoing commitment of the life science business of Merck KGaA, Darmstadt, Germany to supporting early-stage biotech companies developing innovative therapies for patients. To date, more than 40 companies worldwide have received grants and technical support across a wide range of therapeutic areas including cancer, neurological diseases, and cardiovascular disorders. The company will continue this global effort with upcoming grant awards in Asia-Pacific (October) and Europe, the Middle East, and Africa (November). About the Life Science business of Merck KGaA, Darmstadt, Germany The Life Science business of Merck KGaA, Darmstadt, Germany, which operates as MilliporeSigma in the U.S. and Canada, has more than 26,000 employees and more than 55 total manufacturing and testing sites worldwide, with a portfolio of more than 300,000 products focused on scientific discovery, biomanufacturing and testing services. Merck KGaA, Darmstadt, Germany, a leading science and technology company, operates across healthcare, life science and electronics. Around 62,000 employees work to make a positive difference to millions of people's lives every day by creating more joyful and sustainable ways to live. From providing products and services that accelerate drug development and manufacturing as well as discovering unique ways to treat the most challenging diseases to enabling the intelligence of devices – the company is everywhere. In 2024, Merck KGaA, Darmstadt, Germany, generated sales of € 21.2 billion in 65 countries. The company holds the global rights to the name and trademark 'Merck' internationally. The only exceptions are the United States and Canada, where the business sectors of Merck KGaA, Darmstadt, Germany, operate as MilliporeSigma in life science, EMD Serono in healthcare and EMD Electronics in electronics. Since its founding in 1668, scientific exploration and responsible entrepreneurship have been key to the company's technological and scientific advances. To this day, the founding family remains the majority owner of the publicly listed company. For more information about Merck KGaA, Darmstadt, Germany, visit to register again for your online subscription of this service as our newly introduced geo-targeting requires new links in the email. You may later change your selection or discontinue this service.
Bloomberg
3 days ago
- Business
- Bloomberg
Goldman, JPMorgan See Germany Leading Deals Revival in Europe
German dealmaking activity is poised to see the strongest revival in Europe thanks to a new €500 billion ($576 billion) government fund for infrastructure and climate projects, according to Goldman Sachs Group Inc. and JPMorgan Chase & Co. Deals involving German companies amount to about $79 billion so far this year, an about 50% increase from the same period in 2024, according to data compiled by Bloomberg. Outbound investments by German companies are leading the chart, including Siemens AG's proposed $5.1 billion takeover of R&D software maker Dotmatics and Merck KGaA 's deal for Springworks Therapeutics Inc. in the US.
Globe and Mail
4 days ago
- Business
- Globe and Mail
Microcarriers Market to Hit USD 3.05 Billion by 2029 with 8.0% CAGR
"Key players in the microcarriers market include Thermo Fisher Scientific Inc. (US), Danaher Corporation (US), Merck KGaA (Germany), Sartorius AG (Germany), Corning Incorporated (US), FUJIFILM Holdings Corporation (Japan), BD (US), Eppendorf SE (Germany), Lonza (Switzerland)" Browse 761 market data Tables and 57 Figures spread through 557 Pages and in-depth TOC on "Microcarriers Market by Product (Equipment (Single Use Bioreactor, SSB, Cell Counter, Filtration), Consumables (Media, Reagent), Beads (Natural (Collagen), Synthetic (Polystyrene)), Application (Vaccine, CGT, Stem Cells) - Global Forecast to 2029 The global Microcarriers market, valued at US$2.03 billion in 2023, is forecasted to grow at a robust CAGR of 8.0%, reaching US$2.08 billion in 2024 and an impressive US$3.05 billion by 2029. Market growth is attributed to rising investments in cell & gene therapy research, growing preference for single-use technologies, and increasing R&D spending for biopharmaceutical production. However, the high cost of cell biology research and limitations in high-density cell culture production are expected to hinder the market growth over the forecast period. Download PDF Brochure: Browse in-depth TOC on " Microcarriers Market" 761 - Tables 57 - Figures 557 - Pages Based on product, the microcarriers market is segmented into consumables and equipment. The consumables segment accounted for the largest share of the microcarriers market. The large share of the consumables segment is attributed to the repeated purchase and requirement in bulk quantities of sera, media, and reagents for various microcarrier cell culture applications. Additionally, increasing production and development of advanced biopharmaceuticals is driving the growth of the segment in microcarriers market. Among application segment, the microcarriers market is segmented into tissue engineering and regenerative medicine, biopharmaceutical production, and other applications. The biopharmaceutical production segment accounted for the largest share of the microcarriers market. The large share of the biopharmaceutical production segment can be attributed to the commercial expansion of major pharmaceutical companies, growing regulatory approvals for cell culture-based vaccines, and increasing demand for monoclonal antibodies (mAbs). Among end user segment, the microcarriers market is segmented into pharmaceutical & biotechnology companies, academic and research institutes, contract research organizations & contract manufacturing organizations, and cell banks. The pharmaceutical & biotechnology companies segment accounted for the largest share of the microcarriers market. Rising awareness about the benefits of cell-based vaccines, growing regulatory approvals for cell-based vaccines, and a focus on commercial expansion are the major factors driving the growth of this segment. The microcarriers market is segmented by region into six key areas, namely North America, Europe, Asia Pacific, Latin America, the Middle East, and Africa. In 2023, North America dominated the market followed by Europe at second position and Asia Pacific was at third position. The majority share of the market in North America. The key factors driving the growth of the market in North America include increasing demand for cell-based therapies, strong government support for stem cell research, and the presence of a well-established pharmaceutical industry that is likely to drive the growth of the market. The market in Canada is likely to grow in the coming years due to several government initiatives and the intensification of genomics R&D through the Genomic Applications Partnership Program (GAPP) in the country. In addition, the US accounted for the largest market share in the North American microcarriers market. Major share of the country is determined by factors like well-established pharmaceutical and biotechnology sector, cell therapy and biologics, and regulatory vaccine approvals. Increasing incidences of diseases like cancer along with high funding for the life sciences research are also contributing to the major share of the country. For example, According to the National Cancer Institute, there were nearly 2 million people who were suffering from US Cancer cases in 2023. The current treatment options will cater to the unmet demands if cell-based therapies are employed. Since microcarrier culture technology is used in the R&D and production of vaccines and antibiotics, it is likely that these factors will create a large number of opportunities for the growth of the microcarriers market. Europe is the second largest market after North America. The availability of government funding, growth in the biotechnology and pharmaceutical sectors, and the rise in the number of conferences, symposia, seminars, trade fairs, annual events, and workshops being organized in Europe that focus on creating awareness about microcarriers are expected to drive the growth of the market in the region. These factors help increase awareness about current technological advancements and aid in the discussion of various challenges and opportunities prevailing in the industry. Such events also offer market players the opportunity to showcase their products and communicate with stakeholders while helping scientists and researchers to exchange experiences. According to the Alliance for Regenerative Medicine (ARM), a global advocate for regenerative and advanced therapies, out of 843 regenerative medicine companies globally, Europe houses 234. Moreover, In 2023, the Asia Pacific is third largest market for microcarriers. This surge in the regional market is attributed to various factors such as government backing for cell-based vaccine production and therapies, expansion initiatives by key market players in emerging Asian economies, heightened vaccine manufacturing capacities of major companies, increased research and development investments by biotechnology and pharmaceutical firms, collaborative ventures in bioprocessing, a growing elderly population, amplified focus on regenerative medicine research, and the upsurge in preclinical/clinical research particularly in China and India. Thermo Fisher Scientific Inc. (US), Merck KGaA (Germany), and Danaher Corporation (US) holding the significant global market share and the global microcarriers market is highly cosolidated. Thermo Fisher Scientific Inc. (US) Thermo Fisher Scientific (US) is a leading player in the microcarriers market. The company has strong brand image, robust product portfolio, and product development focus. The company offers its products through well-established brands such as Gibco, Nunc, Countess, Dynabeads, and HyPerforma. The company focuses on product launches, expansion, and acquisition to strengthen the position in the market. For example, in September 2023, the company introduced Gibco CTS Detachable Dynabeads, a groundbreaking platform with an innovative active-release mechanism designed for clinical and commercial cell therapy manufacturing. Merck KGaA (Germany) Merck KGaA is a leading science and technology company with a strong global presence in more than 120 countries. The company has a portfolio of more than 300,000 life science products that support a broad customer base. Merck has been a prominent player in the life sciences industry, offering various products and services to support researchers and biomanufacturers. The company has a comprehensive portfolio that includes cell culture media, reagents, and other essential tools for bioprocessing. Merck majorly focuses on expansions in key geographies to increase its customer base. In June 2023, Merck KGaA expanded its reagent manufacturing facility in Nantong, China with an investment of about USD 76.5 million. Danaher Corporation (US) Danaher Corporation is one of the leading companies in the microcarriers market, attributed to a strong product portfolio, recent acquisitions, and partnerships. Danaher Corporation (Cytiva) (US) offers a wide range of products, including microcarriers, bioreactors, media, and reagents, which greatly expanded Danaher's position and offerings in the microcarriers market. The Pall Corporation subsidiary is also active in this market and offers single-use and stainless-steel bioreactors and filtration equipment. In May 2023, Cytiva and the life sciences business of Pall Corporation completed their integration and are now united as one business under the Cytiva brand. In October 2023, Cytiva opened a new manufacturing facility in Pune, India, which will double its manufacturing capacity in the country. The facility will produce bioprocessing equipment, including tangential flow, virus filtration, and inactivation systems, to support the Indian biopharmaceutical industry. For more information, Inquire Now!
Yahoo
12-06-2025
- Health
- Yahoo
EMD Serono Presents Results on Efficacy and Safety of Enpatoran in Systemic Lupus Erythematosus (SLE) at EULAR 2025
Cohort B of the Phase 2 study indicates all doses of enpatoran were associated with higher BICLA response rates compared with placebo, though the primary endpoint of BICLA dose-response relationship at Week 24 was not met Data show encouraging efficacy in a large subgroup of SLE patients with active cutaneous manifestations at baseline, including improved response rates in key disease activity measurements There is a substantial unmet treatment need for the estimated 70-80% of SLE patients who experience active cutaneous manifestations, which can profoundly impact quality of life1 BOSTON, June 12, 2025--(BUSINESS WIRE)--Not intended for media outside the U.S. or Canada EMD Serono, the Healthcare business of Merck KGaA, Darmstadt, Germany, in the U.S. and Canada, a leading science and technology company, today announced the presentation of detailed results from Cohort B of the global Phase 2 WILLOW study (NCT05162586) evaluating enpatoran, an investigational, oral, novel TLR7/8 inhibitor in systemic lupus erythematosus (SLE). Although it did not meet the primary endpoint of dose-response relationship, when compared to placebo, enpatoran demonstrated improvements in measures of both systemic and cutaneous disease activity in prespecified SLE subpopulations despite standard of care (SoC), including those with active cutaneous manifestations at baseline [(CLASI-A) ≥8], and was overall well tolerated. These findings will be presented in a late-breaking oral presentation at the 2025 European Congress of Rheumatology (EULAR) in Barcelona (Abstract # LB0004). "Analyses of Cohort B contribute to our understanding of enpatoran's potential to address the critical unmet needs for patients living with lupus, including those experiencing significant skin manifestations. These manifestations are often part of the systemic activity or flare, which can be painful and have a considerable impact on quality of life," said principal investigator Prof. Eric Morand, from Monash University and Monash Health. "The improvements observed in key disease measures represent a meaningful advancement in our ongoing investigation of the TLR7/8 inhibition approach for patients insufficiently managed by current therapies." WILLOW is a global, multicenter, randomized, placebo-controlled Phase 2 study evaluating three doses of oral enpatoran taken twice daily (25 mg, 50 mg and 100 mg) versus placebo plus SoC over 24 weeks. The study features a unique design across two lupus cohorts, including both patients with active SLE and cutaneous lupus erythematosus (CLE). Cohort B of the study was designed to evaluate the dose-response relationship of enpatoran in reducing disease activity, based on the British Isles Lupus Assessment Group (BILAG)-based Composite Lupus Assessment (BICLA) response rate at Week 24 and enrolled SLE patients who had moderate or severe active disease despite SoC. Cohort B showed positive results in secondary and exploratory endpoints and within prespecified patient subpopulations. In patients with active skin disease (CLASI-A ≥8), BICLA response rates were up to 58.6% while placebo response rates were 31.7%, and up to 60.5% of patients receiving enpatoran showed a CLASI-70 response, compared with 26.8% for placebo, at Week 24. In addition, the subgroups of patients with high corticosteroid (prednisone-equivalent ≥10 mg/day) use and those with high interferon gene signature (IFN-GS) at baseline also showed higher and relevant BICLA response rates for enpatoran compared to placebo. As presented earlier this year at LUPUS 2025, Cohort A analyses from the WILLOW study showed clinically meaningful improvement in disease activity in patients with CLE and mild SLE with active lupus rash at Weeks 16 and 24. Overall, for skin-related signs and symptoms, comparable improvements were observed in Cohort B relative to Cohort A, reinforcing the potential efficacy of enpatoran in patients with cutaneous manifestations of lupus erythematosus with or without systemic disease. "The efficacy and tolerability results from Cohort B, particularly among those with active skin involvement—a manifestation that affects most lupus patients—are consistent with our observations from Cohort A. The lupus rash is not only a visible symptom but is also closely linked to the underlying systemic activity of lupus," said Jan Klatt, Head of Development Unit Neurology & Immunology for the Healthcare business of Merck KGaA, Darmstadt, Germany. "We are set to initiate regulatory discussions with key health authorities to determine the most effective pathway for bringing enpatoran to patients." Enpatoran was well-tolerated and exhibited a manageable safety profile consistent with previous studies, with no new safety signals identified. Rates of treatment-emergent adverse events (TEAEs) were comparable between all enpatoran arms and placebo, ranging from 60.6% to 64.2%, and the most frequently reported TEAEs were infections and infestations. These results further support the anticipated favorable safety profile of enpatoran. About Enpatoran Enpatoran is a selective Toll-like receptor (TLR)7/8 inhibitor under investigation for the treatment of systemic lupus erythematosus (SLE) and cutaneous lupus erythematosus (CLE). By inhibiting TLR7/8 activation, enpatoran may help reduce pro-inflammatory cytokines and autoantibody production, potentially addressing underlying mechanisms of chronic inflammation and disease progression in lupus. With its novel proposed mechanism of action and oral administration, enpatoran has the potential to be a first-in-class treatment for patients across lupus conditions. Enpatoran is currently under clinical investigation and is not approved for any use anywhere in the world. About the Phase 2 WILLOW Clinical Study WILLOW (NCT05162586) is a randomized, double-blind, placebo-controlled Phase 2 proof of concept and dose-finding study designed to evaluate the efficacy and safety of enpatoran in patients with systemic lupus erythematosus (SLE) and cutaneous lupus erythematosus (CLE). The study incorporates a basket design, including two cohorts – Cohort A including patients with CLE or SLE with active lupus rash and Cohort B including patients with active SLE. The WILLOW study aims to advance the understanding of enpatoran's therapeutic potential and to help address significant unmet needs in lupus treatment. About Lupus Erythematosus Lupus erythematosus is a chronic autoimmune disease that can affect various parts of the body, including the skin, joints, kidneys and other organs. It occurs when the immune system mistakenly attacks healthy tissues, leading to inflammation, pain and potential organ damage. There are multiple types of lupus, with systemic lupus erythematosus (SLE) and cutaneous lupus erythematosus (CLE) being two primary forms. Symptoms can range from mild to life-threatening, often including fatigue, joint pain, rashes and organ involvement. Lupus disproportionately impacts women and people of color, and despite available treatments, many patients experience unmet needs due to limited efficacy or side effects. EMD Serono in Neurology and Immunology EMD Serono has a long-standing legacy in neurology and immunology, with significant R&D and commercial experience in multiple sclerosis (MS). The company's current MS portfolio includes two products for the treatment of relapsing MS – Rebif® (interferon beta-1a) and MAVENCLAD® (cladribine) tablets. EMD Serono aims to improve the lives of patients by addressing areas of unmet medical needs. In addition to EMD Serono's commitment to MS, the company also has a pipeline focusing on discovering new therapies that have potential in other neuroinflammatory and immune-mediated diseases, including systemic lupus erythematosus (SLE), cutaneous lupus erythematosus (CLE) and generalized myasthenia gravis (gMG). About EMD Serono, Inc. EMD Serono - the healthcare business of Merck KGaA, Darmstadt, Germany in the U.S. and Canada - aspires to create, improve and prolong life for people living with difficult-to-treat conditions like infertility, multiple sclerosis and cancer. The business is imagining the future of healthcare by working to translate the discovery of molecules into potentially meaningful outcomes for people with serious unmet medical needs. EMD Serono's global roots go back more than 350 years with Merck KGaA, Darmstadt, Germany. Today, the business has approximately 1,050 employees around the country with commercial, clinical and research operations in Massachusetts. About Merck KGaA, Darmstadt, Germany Merck KGaA, Darmstadt, Germany, a leading science and technology company, operates across life science, healthcare and electronics. More than 62,000 employees work to make a positive difference to millions of people's lives every day by creating more joyful and sustainable ways to live. From providing products and services that accelerate drug development and manufacturing as well as discovering unique ways to treat the most challenging diseases to enabling the intelligence of devices – the company is everywhere. In 2024, Merck KGaA, Darmstadt, Germany, generated sales of € 21.2 billion in 65 countries. The company holds the global rights to the name and trademark "Merck" internationally. The only exceptions are the United States and Canada, where the business sectors of Merck KGaA, Darmstadt, Germany, operate as MilliporeSigma in life science, EMD Serono in healthcare and EMD Electronics in electronics. Since its founding in 1668, scientific exploration and responsible entrepreneurship have been key to the company's technological and scientific advances. To this day, the founding family remains the majority owner of the publicly listed company. 1 Cojocaru M, Cojocaru IM, Silosi I, Vrabie CD. Manifestations of systemic lupus erythematosus. Maedica (Bucur). 2011 Oct;6(4):330-6. PMID: 22879850; PMCID: PMC3391953. View source version on Contacts Media Relations Phone: +1 781 427 1892 Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
