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New York Post
11-06-2025
- Health
- New York Post
Rare cancer diagnoses surge dramatically among millennials, Gen X
A rare type of cancer is growing among millennials and members of Generation X, new research shows. Diagnoses of appendix cancer have tripled in the US for people born between 1976 and 1984 — and it has quadrupled for those born between 1981 and 1989. Advertisement The study was published on Monday in the Annals of Internal Medicine. Researchers from the Vanderbilt University Medical Center analyzed data from the National Cancer Institute's Surveillance, Epidemiology and End Results (SEER) Program to arrive at these findings. 'When you take these alarming rates that we are seeing for appendiceal cancer across generations, together with the fact that one in every three patients diagnosed with appendiceal cancer is diagnosed under the age of 50, these point to a timely need for everyone to be aware of the signs and symptoms of appendix cancer,' said lead author Andreana Holowatyj, PhD, assistant professor of Medicine at Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, in a press release from the university. Cancer of the appendix is rare, affecting only about one or two people per million each year in the US, according to the National Cancer Institute (NCI). Even so, doctors emphasize the importance of seeking medical attention if symptoms emerge. Advertisement 3 Appendix cancer has been rising among members of Generation X and millennials. Chinnapong – 'Ruling out the possibility of an appendix cancer diagnosis, or diagnosing it early, is important for this cancer as we continue to learn what factors may be contributing to this worrisome trend,' Holowatyj said. Appendiceal cancer forms in the appendix, which is a small organ located in the lower right abdomen. There are two main types: epithelial appendiceal cancer, which involves the cells of the lining of the appendix, and neuroendocrine appendiceal cancer, which results from the growth of neuroendocrine (carcinoid) tumors of the appendix, the NCI states. Advertisement In early stages of the disease, most people do not notice symptoms. 3 The rates have tripled in the US among people born between 1976 and 1984 — while quadrupling for those born between 1981 and 1989. Peakstock – As the cancer progresses, common symptoms include pain, a bloated feeling, a mass in the abdomen, nausea and vomiting, and sudden feelings of fullness while eating, according to the above source. Common treatments for this type of cancer include surgery to remove the appendix and any other affected organs, as well as chemotherapy to kill any metastasized cancer cells. Advertisement Based on the study findings, the researchers are calling for increased awareness among both the public and the medical community. 'As incidence rates in younger generations are often indicative of future disease burden, these results support the need for histology-specific investigations of appendiceal adenocarcinoma, as well as increased education and awareness of appendiceal adenocarcinomas among healthcare providers and the public,' the study stated. 3 Annals of Internal Medicine published the study on Monday, as researchers from Vanderbilt University Medical Center analyzed data from the National Cancer Institute's Surveillance Epidemiology and End Results (SEER) Program. charnsitr – There are no standard screening guidelines or risk factors for appendix cancer, which means up to half of diagnoses occur after the disease has already spread, according to the researchers. Five-year survival rates for appendix cancer range from 10% to 63%. The new study received funding from the Appendix Cancer Pseudomyxoma Peritonei (ACPMP) Research Foundation and the National Institutes of Health.
Yahoo
11-06-2025
- Health
- Yahoo
Rare cancer diagnoses surge dramatically among millennials and Gen X
A rare type of cancer is growing among millennials and members of Generation X, new research shows. Diagnoses of appendix cancer have tripled in the U.S. for people born between 1976 and 1984 — and it has quadrupled for those born between 1981 and 1989. The study was published on Monday in the Annals of Internal Medicine. Common Menopause Medication Might Prevent Breast Cancer While Treating Hot Flashes Researchers from the Vanderbilt University Medical Center analyzed data from the National Cancer Institute's Surveillance, Epidemiology and End Results (SEER) Program to arrive at these findings. "When you take these alarming rates that we are seeing for appendiceal cancer across generations, together with the fact that one in every three patients diagnosed with appendiceal cancer is diagnosed under the age of 50, these point to a timely need for everyone to be aware of the signs and symptoms of appendix cancer," said lead author Andreana Holowatyj, PhD, assistant professor of Medicine at Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, in a press release from the university. Read On The Fox News App Fda Approves First Ai Tool To Predict Breast Cancer Risk Cancer of the appendix is rare, affecting only about one or two people per million each year in the U.S., according to the National Cancer Institute (NCI). Even so, doctors emphasize the importance of seeking medical attention if symptoms emerge. "Ruling out the possibility of an appendix cancer diagnosis, or diagnosing it early, is important for this cancer as we continue to learn what factors may be contributing to this worrisome trend," Holowatyj said. Appendiceal cancer forms in the appendix, which is a small organ located in the lower right abdomen. There are two main types: epithelial appendiceal cancer, which involves the cells of the lining of the appendix, and neuroendocrine appendiceal cancer, which results from the growth of neuroendocrine (carcinoid) tumors of the appendix, the NCI states. In early stages of the disease, most people do not notice symptoms. As the cancer progresses, common symptoms include pain, a bloated feeling, a mass in the abdomen, nausea and vomiting, and sudden feelings of fullness while eating, according to the above source. Common treatments for this type of cancer include surgery to remove the appendix and any other affected organs, as well as chemotherapy to kill any metastasized cancer cells. Based on the study findings, the researchers are calling for increased awareness among both the public and the medical community. Click Here To Sign Up For Our Health Newsletter "As incidence rates in younger generations are often indicative of future disease burden, these results support the need for histology-specific investigations of appendiceal adenocarcinoma, as well as increased education and awareness of appendiceal adenocarcinomas among healthcare providers and the public," the study stated. There are no standard screening guidelines or risk factors for appendix cancer, which means up to half of diagnoses occur after the disease has already spread, according to the researchers. Five-year survival rates for appendix cancer range from 10% to 63%. For more Health articles, visit The new study received funding from the Appendix Cancer Pseudomyxoma Peritonei (ACPMP) Research Foundation and the National Institutes of article source: Rare cancer diagnoses surge dramatically among millennials and Gen X
NDTV
10-06-2025
- Health
- NDTV
Rare Appendix Cancer On Rise Among Millennials And Gen X: Study
A rare appendix cancer is rapidly increasing among Generation X and millennials, a new study has revealed. When compared to previous generations, the incidence has tripled or quadrupled, it added. According to a paper published Monday in the Annals of Internal Medicine, appendiceal adenocarcinoma (AA) rates have tripled among Gen X and quadrupled among millennials compared to previous generations, based on an analysis of a National Cancer Institute database. The incidence of appendiceal adenocarcinoma is increasing in all age groups in the United States. Although they have not yet been studied, birth cohort patterns of AA can offer new etiologic hints on the rising prevalence. Vanderbilt University Medical Centre researchers examined data from the Surveillance, Epidemiology and End Results (SEER) program of the National Cancer Institute, which tracked incidents between 1975 and 2019. According to their data, the incidence of appendix cancer has quadrupled for those born in 1985 and tripled for those born in 1980 when compared to those born in 1945. Although appendix cancer is very rare - roughly 3,000 new cases are diagnosed each year in the US, a small portion of the more than 150,000 instances of colorectal cancer - there is a noticeable generational trend. A total of 4,858 cases of appendix cancer were reported between 1975 and 2019. The increase in appendix cancer rates, according to experts, is similar to trends in other gastrointestinal cancers, like colorectal and stomach cancers. They are also on the rise among those under 50. Increased use of ultra-processed foods, particularly processed meats and sugary beverages, as well as increased rates of obesity and metabolic syndrome, are possible causes of appendiceal adenocarcinoma (AA) among younger generations. Dr Andreana Holowatyji, the study's principal author, stressed the rise was not the result of more appendectomies because surgery rates remained constant over time. It indicates more significant lifestyle changes and environmental risk factors. "There is a disproportionate burden of appendix cancer among young individuals," Dr Andreana Holowatyji told NBC News. Early detection of appendix cancer can be difficult since its symptoms - bloating, changes in bowel habits, and appetite loss - can be ambiguous. The exact causes remain unidentified, and scientists emphasise the importance of more research into environmental exposures and molecular alterations that could contribute to appendix cancers.
Economic Times
09-06-2025
- Health
- Economic Times
Appendix cancer rates quadruple among millennials, raising alarms for younger generations
IANS Appendix cancer rates quadruple among millennials A new study published in the Annals of Internal Medicine has revealed a sharp and troubling rise in appendix cancer rates among younger generations, particularly millennials and Generation X. Researchers at Vanderbilt University Medical Center analyzed data from the National Cancer Institute's Surveillance, Epidemiology and End Results (SEER) program, tracking cases from 1975 to 2019. Their findings show that the incidence of appendix cancer has tripled among those born in 1980 and quadrupled for individuals born in 1985, compared to people born in 1945. Although appendix cancer remains rare—about 3,000 new cases are diagnosed annually in the United States, a fraction of the more than 150,000 cases of colorectal cancer—the generational trend is significant. The study's lead author, Dr. Andreana Holowatyji, emphasized that the rise is not due to increased appendectomies, as surgical rates have remained stable over the increase points to broader shifts in environmental and lifestyle risk factors. Experts suggest that the surge in appendix cancer rates mirrors patterns seen in other gastrointestinal cancers, such as colorectal and stomach cancers, which are also rising among people under 50. Potential contributors include higher rates of obesity, metabolic syndrome, and increased consumption of ultraprocessed foods, especially processed meats and sugary beverages. However, the precise causes remain unclear, and researchers stress the need for further investigation into environmental exposures and molecular changes that may drive of appendix cancer can be vague—such as bloating, changes in bowel habits, and loss of appetite—making early diagnosis challenging. The study underscores the importance of greater awareness among both healthcare professionals and the public, as early detection remains critical for better appendix cancer incidence rising sharply in younger adults, the findings highlight an urgent need for continued research and public health vigilance to address this emerging cancer trend.
Time of India
09-06-2025
- Health
- Time of India
Appendix cancer rates quadruple among millennials, raising alarms for younger generations
Live Events (You can now subscribe to our (You can now subscribe to our Economic Times WhatsApp channel A new study published in the Annals of Internal Medicine has revealed a sharp and troubling rise in appendix cancer rates among younger generations, particularly millennials and Generation X. Researchers at Vanderbilt University Medical Center analyzed data from the National Cancer Institute 's Surveillance, Epidemiology and End Results (SEER) program, tracking cases from 1975 to 2019. Their findings show that the incidence of appendix cancer has tripled among those born in 1980 and quadrupled for individuals born in 1985, compared to people born in appendix cancer remains rare—about 3,000 new cases are diagnosed annually in the United States , a fraction of the more than 150,000 cases of colorectal cancer—the generational trend is significant. The study's lead author, Dr. Andreana Holowatyji, emphasized that the rise is not due to increased appendectomies, as surgical rates have remained stable over the increase points to broader shifts in environmental and lifestyle risk suggest that the surge in appendix cancer rates mirrors patterns seen in other gastrointestinal cancers, such as colorectal and stomach cancers, which are also rising among people under 50. Potential contributors include higher rates of obesity, metabolic syndrome, and increased consumption of ultraprocessed foods, especially processed meats and sugary beverages. However, the precise causes remain unclear, and researchers stress the need for further investigation into environmental exposures and molecular changes that may drive of appendix cancer can be vague—such as bloating, changes in bowel habits, and loss of appetite—making early diagnosis challenging. The study underscores the importance of greater awareness among both healthcare professionals and the public, as early detection remains critical for better appendix cancer incidence rising sharply in younger adults, the findings highlight an urgent need for continued research and public health vigilance to address this emerging cancer trend.
