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Children's Hospital of Philadelphia Researchers Spotlight Adults with Hypoplastic Left Heart Syndrome (HLHS) Thriving Without Transplants
Children's Hospital of Philadelphia Researchers Spotlight Adults with Hypoplastic Left Heart Syndrome (HLHS) Thriving Without Transplants

Yahoo

time4 days ago

  • Health
  • Yahoo

Children's Hospital of Philadelphia Researchers Spotlight Adults with Hypoplastic Left Heart Syndrome (HLHS) Thriving Without Transplants

Study Highlights Largest Single-Center Cohort of Adults with HLHS with Longest Follow-up PHILADELPHIA, June 17, 2025 /PRNewswire/ -- Researchers at Children's Hospital of Philadelphia (CHOP) reported long-term clinical outcomes for the largest single center cohort of individuals who underwent complex reconstructive surgery for hypoplastic left heart syndrome as newborns. In this cohort, more than 30% survived without a transplant to at least 35 years of age. Among these individuals, there was a significant group of adults who reported good to excellent clinical outcomes and quality-of-life (QOL), consistent with a "high-performing" Fontan phenotype. The findings were published today in the Journal of the American College of Cardiology. Prior to this study, limited data existed concerning longer-term outcomes for patients with HLHS. To bridge this gap, researchers examined long-term survival and the impact of patient factors on survival for newborns with HLHS, as well as functional and health outcomes, including QOL in adulthood. "Our study highlights the impact of CHOP's pioneering surgical approaches to pediatric heart disease," said J. William Gaynor, MD, a lead study author and surgeon in the Cardiac Center at Children's Hospital of Philadelphia. "While more research is needed, our findings offer hope for a future where high-functioning adult patients with CHD are the norm." In this retrospective study, researchers analyzed patients with HLHS and associated variants who underwent complex open-heart surgeries between January 1984 and December 2023. The authors noted that while survival has plateaued over the past two decades, they are encouraged by the adult individuals reporting good to excellent health and few Fontan-related complications without a transplant. The study findings also underscore the importance of maintaining cardiac care for adults with congenital heart disease. CHOP's Philadelphia Adult Congenital Heart Disease Center and Fontan Rehabilitation, Wellness, Activity and Resilience Development program (FORWARD) are designed to provide specialized care, evaluation and ongoing monitoring of individuals with single ventricle heart defects and Fontan circulation. In the past, research has primarily focused on identifying "risk factors" associated with worse survival and outcomes for patients with HLHS. However, in the future, CHOP's innovative programs addressing adults with CHD will be instrumental in helping researchers better understand what is driving patient success. "Moving forward, based on these study findings, we plan to focus more research on adults with CHD, looking at why they are doing well without a transplant," said Jack Rychik, MD, Director of the FORWARD program at Children's Hospital of Philadelphia. "For us, success is seeing our patients thrive as adults. We are committed to finding new, personalized ways to help them heal, grow stronger and live their best lives." Dr. Gaynor said they will continue to follow the cohort of adult individuals to better understand their lives in greater depth, including health and wellness, approach to exercise, emotional and cognitive abilities, as well as careers and relationships. This study was funded by a grant from Big Hearts to Little Hearts, an organization aimed at improving the lives of children and adults with CHD through research, programs, and advocacy. Additional funding includes the Mortimer J. Buckley Jr. M.D. Endowed Chair in Cardiac Surgery, the Thomas L. Spray, MD Endowed Chair in Pediatric Cardiothoracic Surgery and the Daniel M. Tabas Endowed Chair in Pediatric Cardiothoracic Surgery at CHOP. Gaynor et al. "Long-term Survival and Patient Reported Outcomes after Staged Reconstructive Surgery for Hypoplastic Left Heart Syndrome." JACC. Online June 16, 2025. DOI: 10.1016/ About Children's Hospital of Philadelphia:A non-profit, charitable organization, Children's Hospital of Philadelphia was founded in 1855 as the nation's first pediatric hospital. Through its long-standing commitment to providing exceptional patient care, training new generations of pediatric healthcare professionals, and pioneering major research initiatives, the hospital has fostered many discoveries that have benefited children worldwide. Its pediatric research program is among the largest in the country. The institution has a well-established history of providing advanced pediatric care close to home through its CHOP Care Network, which includes more than 50 primary care practices, specialty care and surgical centers, urgent care centers, and community hospital alliances throughout Pennsylvania and New Jersey. CHOP also operates the Middleman Family Pavilion and its dedicated pediatric emergency department in King of Prussia, the Behavioral Health and Crisis Center (including a 24/7 Crisis Response Center) and the Center for Advanced Behavioral Healthcare, a mental health outpatient facility. Its unique family-centered care and public service programs have brought Children's Hospital of Philadelphia recognition as a leading advocate for children and adolescents. For more information, visit Contact: Natalie SolimeoChildren's Hospital of Philadelphia267-426-6246solimeon@ View original content to download multimedia: SOURCE Children's Hospital of Philadelphia Sign in to access your portfolio

Conneaut health department studying mosquitos
Conneaut health department studying mosquitos

Yahoo

time06-06-2025

  • Health
  • Yahoo

Conneaut health department studying mosquitos

CONNEAUT — The Conneaut Health Department will start studying the city's mosquito population next week. Conneaut Health Commissioner Nichele Blood said the health department wants to catch mosquitos around the city. 'We set a trap up and it will catch mosquitos for us,' she said. The mosquitos will then be taken to the health department office and frozen for a day, before being sent to an Ohio Department of Health lab for study. Blood said they are primarily interested in learning what species of mosquitos reside in the Conneaut area, and if they carry West Nile Virus. Blood said there have not been any recorded cases of the disease in northeast Ohio recently. According to the ODH website, there have been no cases of the disease in people or mosquitos surveilled across the state so far this year. Blood said the Conneaut Health Department is also monitoring for other mosquito-borne illnesses, including Eastern Equine Encephalitis, St. Louis Encephalitis, La Crosse virus, malaria, zika and yellow fever. 'Most are not common,' she said. The program is being paid for by part of a $8,150 grant the health department received from the Ohio Environmental Protection Agency. The CHD used $5,600 to fund a tire collection at the Conneaut Spring Clean-Up last weekend. Blood said the rest of the grant money is going toward funding the mosquito surveillance and promoting mosquito awareness in Conneaut. Blood said mosquitos thrive in areas where there is standing water, especially unused tires. Blood recommended people take care of items that contain standing water on their properties, including tires, bird baths and toys left outside. People should also make sure to fix screen doors so mosquitos do not get indoors, and make sure to wear mosquito repellent. The CHD will be providing mosquito spray to the public and sending out flyers spreading awareness, Blood said.

Mississippi offers walk-in immunization clinics for students
Mississippi offers walk-in immunization clinics for students

Yahoo

time04-06-2025

  • General
  • Yahoo

Mississippi offers walk-in immunization clinics for students

JACKSON, Miss. (WJTV) – Several County Health Departments (CHD) in Mississippi will hold special walk-in immunization clinics for school registration this summer. The walk-in clinics are for incoming kindergarten and 7th grade students, both of whom have required vaccinations before starting school in the fall. Parents must provide the school with a Certificate of Immunization Compliance (Form 121) prior to school entry. College students can also receive vaccinations during the clinics. Doctors urge Mississippians to brace for Sahara dust effects Clinic hours are 8:00 a.m. to 11:30 a.m. and 1:00 p.m. to 4:30 p.m. on designated days. For a complete list of CHDs holding walk-in clinics and the dates, click here. There is a $10 administration fee per shot if a child does not have insurance; the cost is $20 for college students. Parents should bring a copy of their child's immunization record. Form 121 can be obtained from your child's immunization provider, but the Mississippi State Department of Health (MSDH) now offers MyIR Mobile to check your child's immunizations record online. Only immunization records of Mississippi residents are accessible through the portal. Childhood vaccinations are available at any CHD by appointment. If your child is not up to date on vaccinations, call (855) 767-0170 to schedule an appointment. If you would like to request a medical or religious exemption, review the MSDH process online. Close Thanks for signing up! Watch for us in your inbox. Subscribe Now Copyright 2025 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.

This consumer products giant is a buy after a recent pullback, RBC says
This consumer products giant is a buy after a recent pullback, RBC says

CNBC

time02-06-2025

  • Business
  • CNBC

This consumer products giant is a buy after a recent pullback, RBC says

RBC Capital Markets thinks shares of Church & Dwight could see a rebound as tariff and consumer woes appear to have eased in recent weeks. The company also has a new growth engine with its recent acquisition, according to the firm. Analyst Nik Modi upgraded the consumer products company to outperform from sector perform and lifted his price target by $14 to $114. His new target suggests that the stock can jump about 16% from its latest close. Church & Dwight, which owns brands including Arm & Hammer and Nair, declined 7% on May 1 after the company issued lackluster second-quarter earnings guidance. Year to date, shares have lost 6%. But Modi believes the stock is now trading at a "good entry point" after this pullback, given it has also underperformed the Consumer Staples Select Sector SPDR Fund (XLP) in 2025. "CHD shares have underperformed following a soft Q1 print impacted by destocking, slower category growth, and the impact of tariffs," Modi said. But "after spending time with Church & Dwight management (CEO/ new CFO), we have renewed confidence that the current guide adequately reflects the challenges of the current environment." The analyst is also confident that Church & Dwight will continue to gain market share across most of its portfolio for the rest of the year, highlighting that the company's year-over-year volume share in laundry detergent, mouthwash and skin care has increased year to date. CHD 1Y mountain Church & Dwight stock performance over the past year. Additionally, Modi is optimistic that Church & Dwight's acquisition of hand sanitizer brand Touchland will usher in greater distribution opportunities as well as potential opportunity to drive greater revenue synergy with Sephora. "We are also bullish on the acquisition of Touchland given its product efficacy, differentiation, distribution opportunities and loyal consumer base," he said in a note to clients. "We see this acquisition as more akin to recent acquisitions Hero and TheraBreath and less like acquisitions like Flawless or Vitafusion." Analysts in general aren't fully on board with Church & Dwight. Of the 24 analysts that cover the name, only eight rate it a strong buy or buy, while 11 have a hold rating. Another five rate it as underperform or sell, per LSEG.

Community rallies in Peoria for 2025 Heart of Illinois Congenital Heart Defect Walk
Community rallies in Peoria for 2025 Heart of Illinois Congenital Heart Defect Walk

Yahoo

time01-06-2025

  • General
  • Yahoo

Community rallies in Peoria for 2025 Heart of Illinois Congenital Heart Defect Walk

PEORIA, Ill. (WMBD) — The 2025 Heart of Illinois Congenital Heart Defect Walk brought together families, friends, and supporters this weekend at the Peoria Riverfront. People in attendance shared one common goal: to raise awareness and funding for CHD, a life-threatening condition that affects thousands of children and adults across the country. Pam McMahon, co-chair of the event, emphasized the importance of coming together to support one another and raise awareness. 'We want everybody to come down, enjoy the interaction and the camaraderie with others, and just enjoy a day that is not in the hospital or in the clinic or worrying about what you're going through,' McMahon said. Held along the scenic Peoria Riverfront, the event attracted 28 teams who participated in the one-mile walk and collectively raised more than $40,000 to support CHD research and advocacy efforts. She added that the walk provides an important opportunity for connection. 'It gives families a chance to interact with other families that are going through the same thing that they are. We have a lot of our physicians and providers here today, and they get to see them outside of the office, so they get to interact on a more personal level,' she said. Before the walk kicked off, the riverfront was filled with energy and emotion as dozens gathered to take part in family-friendly activities and listen to heartfelt testimonies from families living with congenital heart defects. Many shared their personal stories of struggle, resilience and hope, creating a strong sense of community and purpose. Although the walk has ended, fundraising efforts continue. Donations will be accepted throughout the month of June to further support CHD research and patient support programs. For more information or to contribute, visit the Heart of Illinois Congenital Heart Walk's website. Copyright 2025 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.

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