Latest news with #Allay


Sharjah 24
a day ago
- Sport
- Sharjah 24
Khorfakkan Club for the Disabled concludes season with 104 medals
Celebrating the team's success and efforts His Excellency Abdullah Saleh Al Naqbi, Chairman of the Club's Board of Directors, congratulated the club's athletes for their impressive accomplishments and exceptional performance throughout the season. He also extended his appreciation to the technical, administrative, and medical teams for their integral roles in reaching these milestones and for their perseverance under pressure. Al Naqbi emphasised that these victories are the result of strong teamwork, continuous training, and unwavering dedication. He commended the players' discipline and cooperation, highlighting their commitment during both training sessions and competitive events. He also encouraged ongoing skill development and urged the athletes to preserve their achievements while continuing to supply national teams with promising talents from the club's youth. Acknowledging the support behind the success Louay Saeed Allay, Vice Chairman of the Club's Board of Directors, credited the club's achievements to the unwavering support of His Highness Sheikh Dr Sultan bin Mohammed Al Qasimi, Supreme Council Member and Ruler of Sharjah. He stressed the Board's ongoing commitment to establishing the club as a pioneering sports institution with a lasting social impact. Allay also highlighted the vital contributions of the Sharjah Sports Council, led by His Excellency Issa Hilal Al Hazami, noting that its continued backing remains a cornerstone of the club's sustained excellence. Early preparations and great ambitions for the next season Looking ahead, Allay reassured the club's fans and supporters that the Board of Directors is fully committed to thorough preparation for the upcoming season. This includes optimal utilization of financial resources, strict adherence to approved budgets, and strategic planning to maintain the club's momentum and build on current successes. Abdul Aziz Al Hammadi: Results reflect long-term planning Abdul Aziz Al Hammadi, Chairman of the Technical Affairs and Talent Care Committee, highlighted that the club's recent achievements stem from long-term strategic planning and targeted training programs. The medal tally reflects the club's continuous investment in both individual and team performance development. He reported that the club had secured 58 local gold medals, along with 15 gold, 16 silver, and 15 bronze in international championships—further solidifying Khorfakkan Club's position as a leader in Paralympic sports with a strong ability to compete at the highest levels. Local dominance and global qualification Khorfakkan Club maintained its dominance on the national stage by winning the Paralympic Committee Athletics Cup for the third consecutive season, in addition to clinching the Powerlifting Cup. The goalball team for the visually impaired achieved second place in only their second local appearance, while the wheelchair basketball team currently tops both the league and cup competitions. Al Hammadi proudly noted that seven players from the club have qualified for the World Athletics Championships, and four athletes have earned spots in the World Powerlifting Championships. He concluded by affirming that these accomplishments are a clear sign that the club is on the right path to producing world-class athletes who will proudly represent the UAE on international platforms.
Yahoo
05-06-2025
- Business
- Yahoo
Allay Therapeutics Announces $57.5M Series D Financing and Venture Debt Line to Advance ATX101 and its Ultra-Sustained Pain Platform for Post-Surgical Pain Management
Series D led by Lightstone Ventures and ClavystBio, supported by leading global syndicate of new and existing investors; Additional venture debt funding led by HSBC Funds to advance ATX101 Phase 2b registration trial of post-surgical pain management in total knee replacement patients, data anticipated in Q4 2025 Joe Zakrzewski joins as Chairman of Allay Board of Directors Maruishi Pharmaceutical, Allay's partner in Japan, expands license territory to S. Korea and Taiwan SAN JOSE, Calif., June 05, 2025--(BUSINESS WIRE)--Allay Therapeutics, a clinical-stage biotechnology company pioneering ultra-sustained analgesic products to transform post-surgical pain management and recuperation, today announced the completion of a $57.5M Series D financing round with leading global investors. Lightstone Ventures and ClavystBio co-led the Series D financing with participation by existing investors NEA, Arboretum Ventures, Vertex Growth, Vertex Ventures Healthcare, and Brandon Capital. New investors joining the round were IPD Capital, EDBI and SGInnovate, and HSBC Innovation Banking also provided additional venture debt financing to the Company. Allay also announced that Joe Zakrzewski, an experienced pharmaceutical executive, has been appointed Chairman of the Board of Directors, and Anselm Tan of ClavystBio will also join Allay's board, associated with the financing. Allay Therapeutics' Japanese partner Maruishi Pharmaceutical has expanded the territory of its license agreement to include South Korea and Taiwan, in addition to Japan. As part of the amendment to the license, Maruishi has also made an additional investment in Allay as part of the Series D financing. Maruishi is currently conducting a Phase I/II multi-center open-label safety study of ATX101 in Japan. Proceeds from the financing supports the Company's Phase 2b registration trial evaluating ATX101 for the treatment of post-surgical pain following total knee replacement (TKA) surgery and advances Allay's ultra-sustained platform of products for other unmet needs after painful surgeries. ATX101 is a novel investigational analgesic designed to provide extended pain relief after surgery, reducing the need for opioids and improving patient recovery. "Lightstone Ventures is pleased to be joined by a strong syndicate of biotechnology and medical device investors in the U.S. and Asia to support Allay with this fundraise to advance the Company's platform of products into pivotal clinical development. The Company is enrolling its Phase 2b registration trial ATX101 in the US for TKA surgeries and are expecting early completion of this trial in the coming months," stated Mike Carusi, Managing Partner at Lightstone Ventures. "It is rewarding to see Allay, which Lightstone Singapore helped to incubate alongside our partners at the Foundry, continue to grow and prosper." "With our recent breakthrough therapy designation (BTD) by FDA and constructive Type B meeting discussions held in March 2025, we have a clear roadmap to complete the ATX101 development program in TKA and are looking at additional indications and unmet needs in orthopedics, plastic surgery, anesthesiology and other soft tissue surgeries," stated Adam Gridley, President & CEO of Allay Therapeutics. "We believe the ATX platform of products driven by our teams in Singapore and the U.S. can help improve patient outcomes, reduce opioid use and improve function more rapidly than currently available therapies." "We are proud to support Allay as they advance best-in-class non-opioid solutions for patients suffering from pain and poor recovery outcomes after surgery. Allay exemplifies ClavystBio's mission to accelerate life sciences technologies from Singapore to the world," said Anselm Tan, Digital Health & MedTech Lead, ClavystBio. "ATX101 is one of several offerings in a pipeline driven by Singapore's R&D excellence, a strong collaboration among international teams, and a global syndicate of investors." Allay's Phase 2b registration trial of 200 participants undergoing total knee arthroplasty (replacement, or TKA surgery) is being conducted at multiple U.S. sites. The trial was initiated in February 2025 and is a three-arm, randomized, controlled study evaluating treatment with ATX101 1,500 mg versus placebo and a bupivacaine active comparator. A prior dose-ranging Phase 2b trial achieved clinically meaningful durable treatment effects with ATX101 versus standard-of-care bupivacaine based on pain intensity out to four weeks, with less use of opioids and meaningful improvement in functional activities up to 60 days following surgery. Based on those prior results, Allay's ATX101 product has received Breakthrough Therapy designation from the FDA. Results from the registration trial will be available in the fourth quarter of 2025 and a Phase 3 trial is planned for 2026. About Joe Zakrzewski:Mr. Zakrzewski has over 30 years of leadership experience in the biotechnology and pharmaceutical industry and has founded a number of biotechnology companies and been an inventor on numerous patents. He currently serves on the Board of Directors of multiple public & privately held companies. During his operating career he was Chairman and CEO of Amarin Pharmaceuticals, a Venture Partner with Orbimed, Chairman, President & Chief Executive Officer of Xcellerex, a privately held company sold to GE Healthcare, and COO of Reliant Pharmaceuticals, a privately held company sold to GSK plc. Prior to this, Mr. Zakrzewski served in various executive roles including global leadership for Business Development at Eli Lilly & Company. He received a BS in Chemical Engineering and an MS in Biochemical Engineering from Drexel University, and an MBA in Finance from Indiana University. About Lightstone VenturesLightstone Ventures is a global venture capital firm investing in biotech and medtech companies pioneering big ideas poised to transform patient outcomes. We were founded in 2012 to empower visionary entrepreneurs with the resources and operational guidance necessary to bring their innovative therapeutics and technologies to the patients who need them most. Our investment team has led deals resulting in 19 acquisitions and 20 initial public offerings over the last two decades. The firm has offices in Boston, Mass., Portola Valley, Calif., and Dublin, Ireland. For more information, please visit About ClavystBioClavystBio is a life sciences investor and venture builder established by Temasek to accelerate the commercialization of breakthrough ideas into health impact. We invest and partner with innovators, entrepreneurs and founders to launch and grow global companies from Singapore. Our focus spans therapeutics, digital health and medtech, with an emphasis on first-in-class science and technology. Our collaborative space, Node 1, provides plug-and-play spaces for ventures that have graduated from incubators to progress to their next milestones. By bringing startups together, we foster a vibrant and supportive community. Since our inception in 2022, ClavystBio has committed over US $220 million in investments in the life sciences sector. For more information, please visit About ATX101ATX101 is a novel investigational configuration of an approved, well-characterized, validated intracellular sodium ion channel blocker, bupivacaine, and a biopolymer that has been designed to provide weeks of pain relief following total knee arthroplasty (TKA, or replacement), a common orthopedic surgery. ATX101 has a high density of drug within its small footprint to allow for ultra-sustained analgesia. It is placed in minutes at the end of standard surgery to deliver its analgesic effect over weeks before eventually dissolving into water and carbon dioxide. The simple procedure does not require specialized training and is intended to replace the existing complex mix of analgesic products used for shorter-term pain management in the post-surgical setting. ATX101 is an investigational product that has not been approved by the U.S. Food and Drug Administration. About Allay TherapeuticsAllay Therapeutics is pioneering ultra-sustained analgesic products to transform post-surgical pain management and recuperation for patients and physicians. Our proprietary technology platform combines validated non-opioid analgesics and biopolymers to create dissolvable candidates to deliver pain relief within a targeted site over weeks: an order of magnitude greater than the longest-lasting pain treatments currently available. Our platform and vision were shaped by The Foundry incubator and Lightstone Venture's Singapore Fund. Allay unites a dynamic, global team of entrepreneurs, scientists, clinicians and innovators in the San Francisco Bay Area and Singapore. Learn more at View source version on Contacts For further details, please contact:InvestorsAdam Mediaallay@ Sign in to access your portfolio


Sharjah 24
18-05-2025
- Entertainment
- Sharjah 24
SGCA calls on global innovators in 'Soft Power'
Organised by the Sharjah Government Media Bureau (SGMB), the award reaffirms its focus on the 'Soft Power' category to recognise innovative communication strategies that use culture, arts, sports, technology, music, and drama to strengthen communication between governments and societies, while shaping global perceptions. This category reflects a modern yet comprehensive approach to human interaction and engagement. The 'Soft Power' category aims to redefine communication by embracing the latest technological advances and creative methods. The award is currently accepting nominations until July 24, 2025. It features 23 categories across five main sectors: Government and international organisations, private sector, individual awards, partner awards, and jury awards. Those interested in participating in the 2025 edition, with winners set to be honoured this September. His Excellency Tariq Saeed Allay, Director General of SGMB, noted that the award highlights the UAE's and Sharjah's efforts to establish an international presence. 'Incorporating soft power into communication helps build global partnerships, attract investment, and encourage cultural and scientific exchange, all of which contribute to long-term social and economic stability,' Allay emphasised. The SGCA promotes the use of tools such as music, film, arts, drama, and sports as effective mediums for public communication. These forms of expression play an important role in overcoming language and cultural barriers, raising public awareness, reinforcing national identity, and promoting shared human values. This year's judging panel, made up of communication and media experts, will evaluate entries in the 'Best Investment in Soft Power to Support Communication Programs' category based on objective criteria. Evaluation will include the originality and clarity of the message, its alignment with a soft power medium, and its global reach. Judges will also assess the message's ability to challenge stereotypes or convey universal human values, along with measuring public engagement. Special emphasis is placed on innovation in communicating the message and its potential to make a lasting impact. Last year, the 'Soft Power' category was awarded to the United Nations Climate Change Conference (COP28), hosted by the UAE. The event earned recognition for its use of creative communication and cultural diplomacy to raise awareness about climate change, while showcasing opportunities for sustainable investment. It was widely considered a standout example of how storytelling can turn a policy message into a global call to action.


Sharjah 24
26-02-2025
- Entertainment
- Sharjah 24
Xposure concluded its 9th edition with over 30000 visitors
Allay confirmed the successful conclusion of the 9th edition of the Xposure International Photography Festival, which saw a wide attendance exceeding 30,000 visitors. This was the first edition held in Aljada area of Sharjah, establishing the festival as a leading global platform in the world of photography and visual arts. In exclusive statements to "Sharjah 24," Allay emphasised that the festival attracted a select group of international and local photographers, offering interactive workshops, panel discussions, and specialised art exhibitions. This made it an exceptional event for photography enthusiasts and those interested in the visual arts. The large turnout highlights the festival's importance in enriching the artistic and educational landscape in photography and enhancing Sharjah's role as a global center for visual creativity. He expressed gratitude and appreciation to the participating photographers, workshop presenters, and everyone involved in the festival, commending the efforts of the organising teams that contributed to providing an exceptional experience for visitors and participants. He affirmed that 'Xposure' will continue to evolve and expand in future editions, remaining a primary destination for photographers and artists from around the world.


Jordan Times
22-02-2025
- Entertainment
- Jordan Times
Xposure 2025 kicks off in Sharjah: Global celebration of photography, storytelling
SHARJAH, UAE — The 9th edition of the Xposure International Photography Festival opened with grandeur as Deputy Ruler of Sharjah and Chairman of the Sharjah Media Council Sheikh Sultan bin Ahmed Al Qasimi inaugurated the event at Aljada, Sharjah. The festival, reaffirming the irreplaceable power of human vision and artistry, extends through February 26, thereby marking the outset of a seven-day global convergence of photography, filmmaking and visual storytelling. Spanning 49,000 square metres, Xposure 2025 brings together 420 renowned photographers, filmmakers and industry experts from 48 countries. Through a dynamic programme composed of solo and group exhibitions, panel discussions and workshops, the festival cements Sharjah's reputation as a global centre for cultural and artistic exchange. In his opening address, Director General of SGMB Tariq Saeed Allay emphasised photography's powerful ability to capture reality and evoke deep human emotion. 'When the first photograph was taken in 1826, the process was far from the simple click of a button we know today. It was a painstaking endeavour requiring hours of preparation and patience," Allay said. "At the time, capturing just 50 images was considered a scientific and artistic achievement, akin to uncovering the secrets of an unseen world. In 2024 alone, nearly two trillion images were taken globally, an undeniable testament to humanity's innate desire to document, express, and preserve memories,' he noted. Contrasting AI-generated renditions of iconic images like the Afghan Monalisa with authentic photography, he posed a pivotal question: 'What gives an image its true power?' The answer, he argued, lies not in algorithms but in the raw, unfiltered vision of photographers who brave the world's harshest landscapes, take risks, and wait for the defining moment — immersing themselves in the lives of others to capture images that resonate, move, and inspire. Allay added that while AI has carved a role for itself in research, analysis, and innovation, no machine can replicate the instinct of the human eye, the depth of human emotion, or the irreplaceable power of lived experience. Reaffirming Xposure's founding purpose, he reiterated the festival's commitment and dedication to honouring and celebrating photographers whose work goes beyond mere technical expertise, through redefining storytelling through patience, dedication, and an unrelenting pursuit of truth. 'And what better place to celebrate such vision than Sharjah?' he said, reinforcing the unshaken Emirati standing as a distinguished global beacon and hub of cultural excellence, literature, and the arts. The festival's global stature was reinforced by a keynote speech by Glen Gainor, who is Head of Production at Amazon Original Films. During the inaugural ceremony, Gainor lauded Sharjah's commitment to education and cultural excellence under the leadership of Supreme Council Member and Ruler of Sharjah Sheikh Sultan bin Mohammed Al Qasimi. He highlighted that beyond words, pointing that photography serves as a universal language, one capable of transcending borders and shaping global narratives. 'Xposure is not just a festival; it is a platform where cultures converge, where ideas take form, and where the world's most pressing issues, from climate change to social justice, find visual representation,' Gainor said. He also noted the transformation of storytelling in the digital arena, where platforms like YouTube and AI-generated images have revolutionised how people consume and generate visual content, warning that 'technology may enhance storytelling, but it can never replace the authenticity, patience, and depth that human photographers bring to their craft.' Moving forward, among Xposure's most compelling discussions delved into the evolving relationship between artificial intelligence and photography. As AI-generated images increasingly blur the boundaries between truth and illusion, Xposure 2025 posed a pivotal question: What ultimately determines an image's authenticity? The festival's opening film explored this theme in depth, drawing a striking visual comparison between pixels in an image and cells in a living organism, each an essential component of a larger whole. Enhanced by a live performance blending poetry and music, the screening reinforced photography's profound ability to shape human awareness and foster global connections. More than just an exhibition, this year's Xposure serves as a call to action. From documenting humanitarian crises to exposing environmental devastation, the festival highlights the critical responsibility of photographers to capture truth in its most unfiltered form. An Immersive Platform for Photography Enthusiasts Xposure 2025 presents a dynamic and engaging experience for both professionals and aspiring photographers. Attendees can take part in specialized workshops, panel discussions, film screenings, portfolio reviews, and guided tours. Also, the fourth edition of the Conservation Summit will spotlight photography's crucial role in capturing environmental challenges and amplifying global awareness. The opening ceremony welcomed a distinguished gathering of guests, including Chairman of the Sharjah Ruler's Office Sheikh Salem bin Abdulrahman Al Qasimi, Director General of the Sharjah Digital Department Sheikh Saud bin Sultan bin Mohammed Al Qasimi, Director General of the Rubu' Qarn Foundation for Creating Leaders and Innovators Sheikha Jawaher bint Abdullah Al Qasimi, and First Lady of Zanzibar Mariam Mwinyi.