Astros at Athletics Prediction: Odds, expert picks, starting pitchers, betting trends, and stats for June 17
It's Tuesday, June 17, and the Astros (41-31) take on the Athletics (30-44). Jason Alexander is slated to take the mound for Houston against JP Sears for the Athletics.
The Athletics picked up the win in game one of the series. Mitch Spence only gave up one run in 5.0 innings.
Let's dive into the matchup and find a sweat or two.
We've got all the info and analysis you need to know ahead of the game, including the latest info on how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Astros at Athletics
Date: Tuesday, June 17, 2025
Time: 10:05PM EST
Network/Streaming: NBCSCA, Space City Home Network
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the Astros at the Athletics
The latest odds as of Tuesday:
Moneyline: Astros (-120), Athletics (+100)
Spread: Astros -1.5
Total: 11.0 runs
Probable starting pitchers for Astros at Athletics
Pitching matchup for June 17, 2025: Jason Alexander vs. JP Sears
Astros: Jason Alexander, (0-0, 18.00 ERA)
Last outing (Los Angeles Dodgers, 5/15): 2.1 Innings Pitched, 9 Earned Runs Allowed, 7 Hits Allowed, 4 Walks, and 1 StrikeoutsAthletics: JP Sears, (5-5, 5.08 ERA)
Last outing (Los Angeles, 6/11): 5.1 Innings Pitched, 2 Earned Runs Allowed, 4 Hits Allowed, 0 Walks, and Strikeouts
Astros: Jason Alexander, (0-0, 18.00 ERA)
Last outing (Los Angeles Dodgers, 5/15): 2.1 Innings Pitched, 9 Earned Runs Allowed, 7 Hits Allowed, 4 Walks, and 1 Strikeouts
Athletics: JP Sears, (5-5, 5.08 ERA)
Last outing (Los Angeles, 6/11): 5.1 Innings Pitched, 2 Earned Runs Allowed, 4 Hits Allowed, 0 Walks, and Strikeouts
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Top betting trends & insights to know ahead of Astros at Athletics
On the road the Astros have won 10 of their last 15 games they have played following a defeat
The Over is 8-5-1 (57%) in the Athletics' games this season with JP Sears as starting pitcher
Betting the Athletics on the Run Line with JP Sears starting would have returned a 0.95-unit profit in 2025
If you're looking for more key trends and stats around the spread, moneyline, and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for tonight's game between the Astros and the Athletics
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Tuesday's game between the Astros and the Athletics:
Moneyline: NBC Sports Bet is recommending a play on the Houston Astros on the Moneyline.
Spread: NBC Sports Bet is leaning towards a play ATS on the Athletics at +1.5.
Total: NBC Sports Bet is recommending a play on the under on the Game Total of 11.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC
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Jay Croucher (@croucherJD)
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Brad Thomas (@MrBradThomas)

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