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IntelliShift Partners with Netradyne to Enhance Overall Safety and Optimize Performance

IntelliShift Partners with Netradyne to Enhance Overall Safety and Optimize Performance

Business Wire28-04-2025

BUSINESS WIRE)--IntelliShift, the connected fleet intelligence platform for safety and operations teams, today announced a strategic partnership with Netradyne, the top provider of AI-powered camera technology, offering fleets 360° visibility across HD cameras for unmatched safety insight and full-scope coverage during all driving operations.
Announced during National Distracted Driving Awareness Month, Netradyne's Driver•i solution integrates directly into IntelliShift's existing advanced data suite, allowing users to make better-informed decisions with real-time data-driven insights.
"The future of fleet operations requires intelligent integrations, and having access to quality data in a single platform is essential to successfully managing asset costs and operator safety,' said Greg Mattes, Chief Product and Technology officer at IntelliShift. 'The partnership with Netradyne will provide fleets access to the IntelliShift award winning platform along with NetraDyne's Driver•i AI dash camera system that offers advanced features to capture and monitor good and bad driving behaviors, in one centralized system that optimizes efficiency and improves safety.'
Being one of the most underreported causes of death in the U.S., distracted driving remains the number one cause of vehicle accidents. This partnership offers a modern solution that identifies and tracks distracted driving habits like rapid acceleration, harsh braking and drifting between lanes, to analyze, evaluate and classify risk on a platform that enables managers to make meaningful changes with actionable insights.
"As fleets continue to leverage more tools, many of them are point solutions and focus on just one department's needs,' continued Mattes. 'IntelliShift is focused on helping fleet operations unify their tools. We are excited to bring the highest standard in AI-powered video safety into the IntelliShift platform and solution offering.'
In 2025, tech stack optimization continues to be a priority for organizations seeking to maximize safety, reduce costs and streamline operations. IntelliShift's new partnership represents the company's commitment to support fleets in optimizing efficiency, ensuring a culture of safety and to continue their mission of zero at-fault accidents.
IntelliShift focuses on more than just providing a single technology platform, with the IntelliShift Services division also providing on-site vehicle upfitting and installation services to truly unify fleet operations and ensure safety. For more information, visit www.intellishift.com.
About IntelliShift
IntelliShift is next-gen fleet intelligence made simple. Designed to solve safety and operational challenges, it is the solution that enables businesses with fleets of vehicles and heavy equipment to easily access all fleet operations data in a single platform. Leveraging 20+ years of expertise in business and hundreds of years collectively as fleet experts, IntelliShift delivers deep fleet data insights to drive better business outcomes. As a trusted partner to mobile and field operations spanning construction, field services, utilities, and last-mile delivery markets, our client-centric approach ensures a seamless deployment, easy integration with existing solutions, and immediate returns through increased productivity, improved safety metrics, and demonstrable reduction in costs per asset. We are proud to work with leading brands, including AmeriGas, PSEG, and OnTrac.

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INVESTOR ALERT: Robbins Geller Rudman & Dowd LLP Announces that Apple Inc. Investors with Substantial Losses Have Opportunity to Lead Class Action Lawsuit
INVESTOR ALERT: Robbins Geller Rudman & Dowd LLP Announces that Apple Inc. Investors with Substantial Losses Have Opportunity to Lead Class Action Lawsuit

Business Wire

time33 minutes ago

  • Business Wire

INVESTOR ALERT: Robbins Geller Rudman & Dowd LLP Announces that Apple Inc. Investors with Substantial Losses Have Opportunity to Lead Class Action Lawsuit

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The filmmaker behind the AI-generated Kalshi ad built an AI studio. It didn't kick off until Veo 3 launched.
The filmmaker behind the AI-generated Kalshi ad built an AI studio. It didn't kick off until Veo 3 launched.

Business Insider

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  • Business Insider

The filmmaker behind the AI-generated Kalshi ad built an AI studio. It didn't kick off until Veo 3 launched.

PJ Accetturo was at a conference in San Francisco about half a mile from Google's I/O keynote address in May when he heard about the tech giant's new tool, Veo 3. "That was the big aha moment I had," Accetturo told Business Insider in an interview. A few months prior, Accetturo launched an AI film studio hoping to capitalize on an untapped opportunity in the filmmaking industry, where he had built his career as a commercial director. While his videos generated thousands of views, he was struggling to find a way to monetize the content. Accetturo said Veo 3 was the perfect format for "making fun of commercials." The Google filmmaking tool has expanded AI cinematography capabilities, making video and audio integration more seamless. Why Accetturo decided to try using Veo 3 While some have expressed concern about AI use in filmmaking for multiple reasons, including its potential to displace workers, Accetturo said he didn't "have a ton of reputation to lose" by being among the first to try. He viewed the challenge of making AI film content as a way to differentiate himself, though, saying that he thought the first person who made a viral commercial ad with Veo 3 would "win." "I'm a perfectly mediocre director," Accetturo said, adding that if he made it as the first big AI director in the space, he'd be a "really big fish in a small pond." For his first project with Veo 3, Accetturo decided to release a parody pharmaceutical commercial called "Puppramin," in which puppies cured depression. He said he stayed up until 3 a.m. making the video with Veo 3. Accetturo said he had finally found the right medium to attract companies. The next day, he said betting company Kalshi reached out and asked him to do a commercial for the NBA finals. How the $2,000 Kalshi ad came together The commercial featured absurd scenes, including a farmer floating in a pool of eggs and an alien chugging beer. A Kalshi spokesperson previously told BI that the video went from idea to live ad in three days and hit around 18 million impressions across mediums in the first 48 hours after it launched. Accetturo said he's currently in discussions with other brands about similar collaborations but isn't ready to name them until the deals are finalized. He added that roughly 400 people have applied to join his studio in the past week. Prior to the ad's release, he had brought on just a few contractors. "It's just kind of been this explosion, pipe bomb in my hand," Accetturo said. Accetturo said he's charging businesses five-figure fees, while his production costs cap at around $2,000 per video. Meanwhile, he said traditional commercial shoots can involve crews of 20 to 100 people and cost companies hundreds of thousands. Accetturo said companies are exploring the possibility of commercial ad campaigns on social media, or ads that could run weekly or daily. For Accetturo, the opportunity could be a game changer. Instead of spending weeks working before and after the shoot, he can spend a couple of days in his underwear creating the entire ad, he said. How AI speeds up his work Accetturo has used — and continues to use — plenty of other AI tools in his production work, like ChatGPT, Gemini, and Midjourney. He said AI chatbots help him write jokes and organize scripts into shot lists. They also assist in building prompt structures with elements like time of day, lighting, characters, and dialogue. Then it fills in the details and generates about 10 prompts he can plug into Veo 3. While he said he typically has to run the process 20 to 30 times to fine-tune the nuances, he said the advantage of Veo 3 is that it renders everything in "one shot," allowing him to meet tight production deadlines. "I just type in text and I get the voices, the sound effects, like everything," Accetturo said. Accetturo said this type of format will likely turn any roles that are "ancillary to the creative core," which he considers to include writing and directing positions, increasingly unnecessary. He said lighting, catering, sound mixers — and even actors to some degree — will no longer be needed. For a TV show he's developing, for instance, Accetturo said he hired one actor and used AI to transform that voice into multiple characters. When asked about whether AI will eventually replace the creative roles as well, Accetturo said he doesn't think AI will surpass human taste in creativity in the near future, but it's a possibility in the next five to 10 years. Right now, people seem to be drawn to the "unhinged Grand Theft Auto-style" of commercials that Veo 3 can generate. However, Accetturo said the approach might not work forever — and if that's the case, he says he'll find the next thing that does.

Ono Pharmaceutical and Vertex Announce Strategic Agreement to Develop and Commercialize Povetacicept in Japan and South Korea
Ono Pharmaceutical and Vertex Announce Strategic Agreement to Develop and Commercialize Povetacicept in Japan and South Korea

Business Wire

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  • Business Wire

Ono Pharmaceutical and Vertex Announce Strategic Agreement to Develop and Commercialize Povetacicept in Japan and South Korea

OSAKA, Japan & BOSTON--(BUSINESS WIRE)--Ono Pharmaceutical Co., Ltd. (Headquarters: Osaka, Japan; President and COO: Toichi Takino; 'Ono') and Vertex Pharmaceuticals Incorporated (Headquarters: Boston, MA, U.S.; CEO: Reshma Kewalramani, M.D.; 'Vertex') today announced an exclusive collaboration and license agreement for the development and commercialization of Vertex's povetacicept in Japan and South Korea. Povetacicept is a recombinant fusion protein therapeutic and dual antagonist of the BAFF (B cell activating factor) and APRIL (a proliferation inducing ligand) cytokines with best-in-class potential being studied for the treatment of immunoglobulin A nephropathy (IgAN), primary membranous nephropathy (pMN) and other serious B cell-mediated diseases. Under the terms of the agreement, Ono will pay Vertex an upfront payment, as well as certain regulatory and commercial milestone payments and tiered royalties. Ono will utilize its extensive development expertise to help advance Vertex's clinical trials for povetacicept and will be responsible for obtaining marketing authorizations in Japan and South Korea. Following approval, Ono will be solely responsible for commercializing povetacicept in these regions. The agreement includes povetacicept for both IgAN and pMN, with the potential to add other indications. 'Vertex has a strong track record of developing innovative therapies for serious diseases. Through this strategic partnership, we can strengthen our late-stage pipeline in the immunology field, which is a key focus area for Ono,' said Toichi Takino, Representative Director, President and Chief Operating Officer of Ono. 'We look forward to collaborating with Vertex to provide this new therapeutic option for patients with IgAN and other autoimmune diseases in Japan and South Korea, and to maximize the value of this treatment.' 'Ono is a proven leader in Japan and South Korea, bringing established local relationships, infrastructure, and nephrology expertise that make them a perfect partner for Vertex as we look to deliver povetacicept to the thousands of potential patients in these countries,' said Reshma Kewalramani, M.D., Chief Executive Officer and President of Vertex. 'We are very pleased to partner with Ono and look forward to close collaboration as we continue to advance this potentially best-in-class treatment for IgAN, pMN and other serious B cell-mediated diseases.' About Povetacicept Povetacicept is a recombinant fusion protein therapeutic and a dual antagonist of the BAFF (B cell activating factor) and APRIL (a proliferation inducing ligand) cytokines, which play key roles in pathogenesis of multiple autoimmune diseases via their roles in the activation, differentiation, and/or survival of B cells, T cells, and innate immune cells. Based upon an engineered TACI (transmembrane activator and calcium modulator ligand interactor) domain, povetacicept has higher binding affinity and greater potency in preclinical studies versus other inhibitors of BAFF and/or APRIL alone and has demonstrated potential best-in-class efficacy in a clinical trial in patients with IgA nephropathy and primary membranous nephropathy. Povetacicept is also in development for multiple serious B cell-mediated diseases including other autoimmune kidney diseases and autoimmune cytopenias. About IgA Nephropathy (IgAN) IgAN is a serious, progressive, life-threatening, B cell-mediated chronic kidney disease that is the most common cause of primary (idiopathic) glomerulonephritis, affecting approximately 300,000 people in the United States and Europe. It is estimated that there are approximately 33,000 diagnosed patients in Japan. IgAN results from deposition of circulating immune complexes consisting of immunoglobulins and galactose-deficient immunoglobulin A (Gd-IgA1) in the renal glomerular mesangium, triggering kidney injury and fibrosis. Up to 72% of adult IgAN patients progress to end-stage renal disease within 20 years. There are no approved therapies that specifically target the underlying cause of IgAN. About Primary Membranous Nephropathy (pMN) Primary membranous nephropathy is a serious, progressive, life-threatening B cell-mediated chronic kidney disease affecting people worldwide, with approximately 150,000 people diagnosed in the U.S. and Europe. It is estimated that there are approximately 6,000 diagnosed patients with pMN in Japan. pMN is a rare glomerular disease that occurs when the body generates an abnormal immune response, including autoantibodies, against proteins that are part of the kidney. Autoantibodies trigger damage and inflammation, especially within the glomeruli (the parts of the kidney that filter blood), impairing the kidneys' ability to properly filter waste and fluid, eventually causing progressive loss of kidney function. There are no approved therapies that specifically target the underlying cause of pMN. About RAINIER RAINIER is a global Phase 3 pivotal trial of povetacicept 80 mg vs. placebo on top of standard of care in approximately 480 people with IgAN. The study is designed to have a pre-planned interim analysis evaluating urine protein to creatinine ratio (UPCR) for the povetacicept arm versus placebo after a certain number of patients reach 36 weeks of treatment. If positive, the interim analysis may serve as the basis for Vertex to seek accelerated approval in the U.S. Final analysis will occur at two years of treatment, with a primary endpoint of total eGFR slope through Week 104. The Phase 3 clinical trial is underway in multiple regions, including the U.S., EU and Asia. Specifically, Japanese and South Korean regulatory authorities have approved the Clinical Trial Application (CTA) for RAINIER, where the Phase 3 trial is underway. About RUBY-3 RUBY-3 is an ongoing, multiple ascending dose, multi-cohort, open label, Phase 1/2 basket study of povetacicept in autoimmune glomerulonephritis, including IgAN, primary membranous nephropathy, lupus nephritis, and ANCA-associated vasculitis with glomerulonephritis where povetacicept is being administered subcutaneously for up to 104 weeks. About Ono Pharmaceutical Co., Ltd Ono Pharmaceutical Co., Ltd. delivers innovative therapies for patients worldwide. Upholding its philosophy of 'Dedicated to the Fight against Disease and Pain,' Ono targets areas with unmet medical needs including oncology, immunology, and neurology, and fosters partnerships with academic and biotech organizations to accelerate drug discovery. Through its affiliate, Deciphera Pharmaceuticals, Ono is accelerating clinical development and commercial operations in the US and Europe to drive global business expansion and further its commitment to patient care. For more information, please visit the company's website at About Vertex Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases and conditions. The company has approved therapies for cystic fibrosis, sickle cell disease, transfusion-dependent beta thalassemia and acute pain, and it continues to advance clinical and research programs in these areas. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including neuropathic pain, APOL1-mediated kidney disease, IgA nephropathy, primary membranous nephropathy, autosomal dominant polycystic kidney disease, type 1 diabetes and myotonic dystrophy type 1. Vertex was founded in 1989 and has its global headquarters in Boston, with international headquarters in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 15 consecutive years on Science magazine's Top Employers list and one of Fortune's 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit or follow us on LinkedIn, Facebook, Instagram, YouTube and X. Ono Forward-Looking Statements In this press release, statements made with respect to current plans, estimates, strategies and beliefs, and other statements that are not historical facts are forward-looking statements about the future performance of the company. These statements are based on current assumptions and beliefs in light of the information currently available and involve known and unknown risks and uncertainties. A number of factors could cause actual results to differ materially from those discussed in the forward-looking statements. Such factors include, but are not limited to: (i) changes in the business environment in the pharmaceutical market and amendments to relevant laws and regulations, (ii) disruptions to product supply due to stagnation or delays in production caused by natural disasters, fires, etc., (iii) the possibility that sales activities for new and existing products may not achieve the expected results, (iv) the emergence of new side effects in post-marketing drugs, and (v) infringements of intellectual property rights by third parties. Information about pharmaceutical products included in this press release is not intended to constitute an advertisement or medical advice. Vertex Forward-Looking Statements This press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, as amended, including, without limitation, statements by Reshma Kewalramani M.D., and Toichi Takino, in this press release, and statements about the terms of and expectations for Vertex's collaboration with Ono, statements about potential benefits and results that may be achieved through the collaboration, statements regarding the future activities of the parties pursuant to the collaboration, including Ono's help to advance clinical trials and Ono's responsibility to obtain marketing authorizations in Japan and South Korea and to commercialize povetacicept in the regions, statements regarding upfront and milestone payments, and potential royalties on future products, and statements about Vertex's plans and expectations for the RAINIER and RUBY-3 clinical trials and potential plans to seek accelerated approval in the U.S. based on interim analysis from the RAINIER trial. While Vertex believes the forward-looking statements contained in this press release are accurate, these forward-looking statements represent the company's beliefs only as of the date of this press release and there are a number of risks and uncertainties that could cause actual events or results to differ materially from those expressed or implied by such forward-looking statements. Those risks and uncertainties include, among other things, that the anticipated benefits and potential of the collaboration between Vertex and Ono may not be achieved on the anticipated timeline, or at all, that data may not support further development of the therapies subject to the collaboration due to safety, efficacy, or other reasons, and other risks listed under the heading 'Risk Factors' in Vertex's annual report filed with the Securities and Exchange Commission (SEC) and available through Vertex's website at and on the SEC's website at You should not place undue reliance on these statements. Vertex disclaims any obligation to update the information contained in this press release as new information becomes available.

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