
Scientists are dropping live mosquitoes out of drones in Hawaii. Here's why.
is an environmental correspondent at Vox, covering biodiversity loss and climate change. Before joining Vox, he was a senior energy reporter at Business Insider. Benji previously worked as a wildlife researcher.
It sounds like something out of a nightmare: a giant drone flying through the sky and dropping containers full of live, buzzing mosquitoes, one of the world's most hated insects.
But in Hawaii, this scenario is very much real. A remotely operated aircraft, about 8 feet long, is flying over remote forests in Maui and releasing cup-shaped capsules full of mosquitoes.
As scary as it might sound, the project is a clever solution to a problem that has long plagued the Hawaiian islands.
Hawaii faces an extinction crisis: It has lost hundreds of animals in the last two centuries, including dozens of land snails and birds, largely due to the spread of non-native species like stray cats and feral pigs. Many native animals found nowhere else on Earth are now gone for good. And several of the creatures that remain are heading in the same direction. Scientists on the islands are quite literally racing to save what wildlife remains.
For the state's avian species — its iconic forest birds, significant, too, to Indigenous Hawaiian culture — the main force of extinction is malaria, a mosquito-borne disease. Mosquitoes, a nonnative pest, were introduced accidentally in the early 1800s by a whaling ship. The blood-suckers proliferated across the islands and later began spreading avian malaria, a blood-borne pathogen they transmit through their bites.
A species of honeycreeper from Kauai called the 'akikiki is now considered functionally extinct in the wild. Robby Kohley/American Bird Conservancy
The kiwikiu, or Maui parrotbill, is another endangered species of honeycreeper. It lives on Maui. Robby Kohley
The disease, which can be fatal, utterly devastated the state's forest birds, and especially a group of species in the finch family known as honeycreepers. There were once more than 50 species of these colorful songbirds across Hawaii, and today all but 17 are extinct. As I've observed firsthand, the forests here have grown silent.
The few honeycreeper species that persist today have been able to evade malaria largely because they live in higher elevations that are too cold for mosquitoes. But now, climate change is warming the islands, allowing the insects to march uphill into the remaining avian strongholds. Some experts describe this as an 'extinction conveyor belt.'
Saving these birds is quite literally a race against the clock. That's where the drone comes in.
Related Welcome to the extinction capital of the world
Fighting mosquitoes with mosquitoes
For more than a year now, a group of environmental organizations have been dropping biodegradable containers of mosquitoes into honeycreeper habitats on Maui and Kauai from helicopters. Now they're starting to do it with giant drones. The containers fall to the ground without a top, and when they land the insects escape into the forest.
Critically, these are not your typical mosquitoes. They're all males, which don't bite, that have been reared in a lab. More importantly, they contain a strain of bacteria called wolbachia that interferes with reproduction: When those males mate with females in the area, their eggs fail to hatch. (That's thanks to a bit of biology magic, referred to as the incompatible insect technique, or IIT.)
Researchers test out aerial mosquito releases using a drone. Adam Knox/American Bird Conservancy
The idea is to continually release these special males into honeycreeper habitat where malaria is spreading as a way to erode the population of biting mosquitoes — and thus suppress the spread of disease. The approach has little ecological downside, said Chris Farmer, Hawaii program director at American Bird Conservancy, a conservation group that's leading the drone effort. Mosquitoes are not native, so local ecosystems and species don't rely on them.
'What this does is it erects an invisible barrier so that these mosquitoes can't get up to the forests where these birds remain,' Farmer told Vox.
Since late 2023, a coalition of organizations known as Birds, Not Mosquitoes has unleashed more than 40 million male mosquitoes across Maui and Kauai. Nearly all of those were in containers tossed out of helicopters, which allow scientists to deliver the insects to remote forest regions where the birds remain.
The group is now testing drones as an alternative. While the helicopters can carry more mosquitoes than drones in one flight — around 250,000, compared to about 23,000 — drones are safer because they're unmanned. They're also easier to fly on demand, says Adam Knox, the drone pilot and project manager for aerial deployment of mosquitoes at American Bird Conservancy.
Dropping mosquitoes out of drones and choppers may sound unreal, but it's the best idea out there to help Hawaii's honeycreepers, said Marm Kilpatrick, an avian malaria expert at the University of California Santa Cruz. Kilpatrick is not affiliated with the mosquito-release project. 'The reason that it's worth doing is that so far, we haven't discovered anything else that can possibly do this better,' Kilpatrick told Vox.
Scientists don't yet know if unleashing reproductively challenged mosquitoes is working and causing the resident mosquito population to crash. It's too soon to tell and the research is still underway, according to Christa Seidl, the mosquito research and control coordinator at Maui Forest Bird Recovery Project, a group leading avian conservation on the island.
But the same approach has worked elsewhere — to stem mosquitoes that spread diseases among humans. Global health advocates have released mosquitoes with wolbachia strains that disrupt reproduction in other parts of the world and seen a massive decline in the incidence of, for example, dengue fever.
'It sounds weird to say, but we're standing on the shoulders of human disease,' Farmer said. 'The IIT we're using for conservation was first developed for human health.'
Endgame for mosquitoes?
Ultimately, the goal is not total elimination of mosquitoes that carry avian malaria in Hawaii. That's likely impossible, Kilpatrick said, unless scientists could release millions or even billions of lab-grown insects all at once.
For the time being, the plan is to regularly — and indefinitely — release the mosquitoes into forests with some of the most endangered birds, such as the kiwikiu, 'ākohekohe, and ʻakekeʻe. Barring any regulatory or technical problems, drone deployments will soon be a regular part of that effort.
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Standard clinical measurements like a person's weight, blood pressure, or cholesterol readings are a useful proxy for potential health issues. Then there are the increasingly popular "biological age" tests available to consumers at home. Most of those look at "epigenetic changes" — how environmental factors affect our gene expression. Proteomics does something different and new. It measures the product that our bodies make based on all those genetic and environmental inputs: proteins. It offers a live assessment of how your body is running, not just how it's programmed. If validated in the next few years, these tests could become key in early disease detection and prevention. They could help influence all kinds of medical decisions, from big ones like "What drugs should I take?" to little ones like "How does my body respond to caffeine or alcohol?" Some high-end longevity clinics are already forging ahead using proteomics to guide clinical recommendations, albeit cautiously. 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"It's really discovery at this moment in time, and at the edge of being clinically meaningful." "Once we have that validated tool, we will just add it to our routine testing and we can just tick the box and say, 'I also want to know if this person is a cardiac ager, or a brain ager, or a muscle ager' because now we have a sensitive parameter — protein — which can be added," Maier said. The two big-name proteomics tests are Olink and SOMAscan. For now, their high-end screening costs around $400-$800 per patient. "I'm losing lots of money at the moment because of proteomics for clinical research!" Maier said. Top aging researchers at Stanford and Harvard are pushing the field forward, racing to publish more novel insights about the human proteome. The latest findings from Harvard aging researcher Vadim Gladyshev's lab, published earlier this year, suggest that as we age, each person may even stand to benefit from a slightly different antiaging grocery list. To research this idea, Gladyshev looked at proteins in the blood of more than 50,000 people in the UK, all participants in the UK Biobank who are being regularly tested and studied to learn more about their long-term health. He tracked their daily habits and self-reported routines like diet, occupation, and prescriptions, comparing those details to how each patient's organs were aging. He discovered some surprising connections. Yogurt eating, generally speaking, tended to be associated with better intestinal aging but had relatively no benefit to the arteries. White wine drinking, on the other hand, seemed to potentially confer some small benefit to the arteries while wreaking havoc on the gut. "The main point is that people age in different ways in different organs, and therefore we need to find personalized interventions that would fit that particular person," Gladyshev told BI. "Through measuring proteins, you assess the age of different organs and you say, 'OK, this person is old in this artery.'" For now, there's too much noise in the data to do more. Dr. Pal Pacher, a senior investigator at the National Institute on Alcohol Abuse and Alcoholism who studies organ aging and injuries, told BI that proteomics is simply not ready for clinical use yet. There's just too much noise in the data. But he imagines a future where a more sophisticated protein clock could help link up which people may be most vulnerable to diseases like early cancer, kidney disease, and more. (A California-based proteomics company called Seer announced last weekend that it is partnering with Korea University to study whether proteomics can help more quickly diagnose cancer in young people in their 20s and 30s.) "How beautiful could it be in the future?" Maier said. "Instead of three hours of clinical investigation, I would have a tool which guides me much, much better, with more validity towards interventions." Read the original article on Business Insider